By constructing hierarchical linear model based on perspectives of Intangible Capital, the paper explored the effects of team-level and individual-level factors on knowledge sharing and creativity. The paper examined the effect of individual human capital and social ties on knowledge sharing and creativity, and the mediating role of knowledge sharing, while the study analyzed the cross-level moderating role of team learning from mistakes. Using the sample of 585 questionnaires from 151 R D teams, the study revealed that individual human capital and social ties had significantly positive influence on knowledge sharing and creativity, and knowledge sharing had a mediating effect between individual human capital, social ties and creativity. The study also found that team learning from mistakes moderated the relationship between human capital, social ties and creativity,and moderated the relationship between speci?c human capital, instrumental ties and knowledge sharing. However the results didn’t show that team learning from mistakes moderated the relationship between general human capital, expressive ties and knowledge sharing.