| p73 基因与p53 抑癌基因的比较 |
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| 引用本文： | 吴小明.p73 基因与p53 抑癌基因的比较[J].惠州学院学报,2003,23(6):56-62. |
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| 作者姓名： | 吴小明 |
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| 作者单位： | 惠州学院理学系,广东,惠州,516015 |
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| 摘 要： | p53 是一种肿瘤抑制基因,它的突变与50 %的人类肿瘤发生有关。p73 基因编码的蛋白质,无论在结构上,还是在功能及调节上均与p53 蛋白相似,且与肿瘤的发生密切相关,本文对此方面的研究结果进行了比较,并对p73 能否作为候选抑癌基因进行了讨论.
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| 关 键 词： | p73 p53 肿瘤 抑癌基因 比较 |
| 文章编号： | 1671-5934(2003)06-0056-07 |
| 修稿时间： | 2003年10月9日 |
A Comparison Between p73 Gene With p53 Tumor Suppressor Gene |
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| WU Xiao-ming.A Comparison Between p73 Gene With p53 Tumor Suppressor Gene[J].Journal of Huizhou University,2003,23(6):56-62. |
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| Authors: | WU Xiao-ming |
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| Abstract: | The occurrence of 50% human tumors is related to mutation of p53 gene.The protein coded by p73 cloned gene is similar to p53 protein not only in structure,but also in functions,and is closely related to the occurrence of tumor.This paper makes a comparison between the research of the two genes and goes further to discuss weather the p73 gene functions as a candidate tumor suppressor gene. |
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| Keywords: | p73 p53 tumor tumor suppressor gene comparison |
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