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1.
In two experiments, we examined the conditions under which signaling an unconditioned stimulus (US) with a nominal conditioned stimulus (CS) interferes with the conditioning of situational cues in defensive freezing in the rat. Subjects received footshock USs that were (1) either signaled or unsignaled and (2) either varied or fixed in their temporal location within the conditioning session. Experiment 1, with only one trial per session, yielded no evidence that signaling affected pretrial freezing using either a fixed or variable interval between placement in the context and shock onset. In a test in which no CSs or footshocks were presented, groups that previously had received footshock at a fixed temporal location showed greatest freezing at around that same time. For groups that had received footshocks at various times, freezing declined across the test session. Experiment 2 showed overshadowing of pretrial freezing after more extensive conditioning with many trials per session, but only if the intershock intervals were variable rather than fixed. 相似文献
2.
In two experiments with rats, we examined the developmental emergence of conditioned freezing following trace and short-delay
conditioning and also included a long-delay comparison group. In the short-delay and trace groups, a 10-sec conditioned stimulus
(CS) was paired with shock; for the trace rats, a 10-sec trace interval followed CS termination. The long-delay groups received
a 20-sec CS paired with shock, to equate for the longer interstimulus interval (ISI) in the trace group. Trace conditioning
emerged later in development than did short-delay conditioning (see Moye & Rudy, 1987). Importantly, long-delay conditioning
emerged in parallel with trace conditioning, at a similar time, and with similar strength. These findings suggest a role for
the longer ISI, as opposed to the unfilled gap per se, in the late emergence of trace conditioning. The role of the hippocampus
in trace conditioning and the possibility that young rats encode the temporal relationship between CSs and unconditioned stimuli
are also considered. 相似文献
3.
One-trial context fear conditioning with immediate shock: The roles of transport and contextual cues
Rick A. Bevins Anthony S. Rauhut Janice E. Mcphee John J. B. Ayres 《Learning & behavior》2000,28(2):162-171
In three experiments, using a total of 120 albino rats, we assessed whether transportation cues might evoke some of the freezing
(i.e., defensive immobility) that we see in a context on a day following a footshock given immediately after placement in
that context. The results suggested that immediate shock could directly condition strong fear to both simulated and actual
transport cues. Although conditioning to transport cues explains some of the freezing that is seen on the test day, it does
not explain all of it. We also found evidence that some of the freezing is due to conditioning to permanent features of the
context in which the immediate shock is given. The results support a role for transport cues in theories of context conditioning
and argue against shock-processing accounts of the conditioning deficit that results from immediate shock. 相似文献
4.
Charles F. Levinthal Ross H. Tartell Carrie M. Margolin Howard Fishman 《Learning & behavior》1985,13(3):228-232
In Experiment 1, four values of conditioned stimulus-unconditioned stimulus interval, or interstimulus interval (ISI) (200, 500, 800, and 1,100 msec) were studied in one trial/day acquisition of the conditioned nictitating membrane response of the rabbit. The 1,100-msec ISI group was superior to the other groups, contrary to the usual findings of ISI studies in the conditioning literature. In Experiment 2, effective conditioning levels were attained with an ISI as long as 2,200 msec, when the intertriai interval was set at either 24 or 48 h. Results are interpreted in terms of the role of orienting responses in the conditioning process. 相似文献
5.
Three experiments with rat subjects sought to enhance one-trial excitatory simultaneous and backward fear conditioning by using a two-element compound conditioned stimulus (CS) instead of only a single element. During conditioning, experimental groups received a 4-sec CS either coextensively with a 1-mA grid-shock unconditioned stimulus (US) or immediately after US termination. In subsequent tests, CSs evoked more lick suppression and freezing in these groups than in various controls. Compound CSs evoked more lick suppression and freezing than did CS elements, but did so equally for experimental and control groups. Therefore, the use of compounds did not enhance conditioning. Unexpectedly, an explicitly unpaired control in which CS followed US termination by 3 min tended to show more CS-evoked suppression and freezing than did a control in which CS preceded US onset by 3 min. This result raises the possibility that associations between the CS and the training context might engender responding to backward-paired CSs. 相似文献
6.
Two strains of rats (albino Wistar and hooded PVG/c) were exposed to a conditioned defensive burying paradigm that consisted of placing rats in a test chamber with bedding material on the floor, shocking them with a shock prod, and recording the time each rat spent in burying responses toward the prod. Various behaviors other than burying (freezing, grooming/paw licking) were observed by a time-sampling procedure during the control, conditioning, and extinction sessions, each of which was 15 min in duration. Wistar rats generally showed behavioral inhibition, as evidenced by less burying, lower exploratory and ambulatory behavior, and higher freezing behavior. PVG/c rats spent significantly more time engaged in burying and accumulated more bedding material in the conditioning session than did the Wistar rats. No significant differences between the two strains of rats were observed during the extinction session in terms of these measurements. The results indicate that Wistar rats have a greater tendency to freeze when coping with the noxious stimulus in a conditioned defensive burying paradigm, whereas the dominant coping style for PVG/c rats is defensive burying. 相似文献
7.
The influence of test-trial delay of CS onset in obtaining response summation of an excitatory CS and an independently conditioned context was investigated. Water-deprived rats were given tone-shock and click-shock pairings in the training context and unsignaled footshocks in the test context. Durations of lick suppression in response to the tone (Test 1) and the click (Test 2) were then assessed in the test context. Licking was more suppressed when CS onset occurred early in the test session (e.g., 0 sec) than when it occurred later in the test session (e.g., 300 sec). The results from control groups that had received shock in an irrelevant context rather than the test context indicated that this effect was due to fear of the test context rather than diffuse, nonassociative fear. With onset of the clicks early in the test session on the second test day, response summation of the test context with the clicks was observed. This suggests that appreciable spontaneous recovery had occurred from any test-context extinction that took place on the first test day. We conclude that early onset of the CS on the test trial favors response summation of CSs and test context. 相似文献
8.
Douglas A. Williams 《Learning & behavior》1994,22(2):203-213
Extinction of rats’ conditioned defensive freezing responses in a context associated with two bouts of massed shock (3 sec) separated by a long unreinforced interbout interval was slower than that in a context associated with distributed shock (60 sec). Resistance to extinction following two bouts of massed shock depended on the rats’ remaining undisturbed in the conditioning context during the long unreinforced interbout interval. Slow extinction of freezing was attributed to either the summation of temporal conditioning at the early and late session times or the formation of an association between the early and late bouts of shock. Importantly, the effects of the two bouts of massed shock could not be explained by what is known about the reinforcing effectiveness of massed shock. 相似文献
9.
In three experiments using rats as subjects, we investigated the degree to which a conditioned flavor aversion transfers from one context to another. Experiment 1, using a one-trial conditioning procedure, found no effect of a change of context on a conditioned aversion. Experiment 2 employed a multitrial procedure and demonstrated that a conditioned aversion was extinguished more rapidly after a change of context. Experiment 3 showed that context change decreased the effectiveness with which a conditioned flavor could block acquisition of an aversion by a second flavor. It is argued that these data cannot be explained in associative terms, and that they constitute evidence of conditionality in a simple aversive conditioning procedure. 相似文献
10.
Twenty-eight male albino rats were given a single 4-sec 1-mA electric-grid-shock unconditioned stimulus (US). In the same session they received two 12-sec conditioned stimuli (CSs). One CS (explicitly unpaired) terminated 180 sec before the US began; the other (backward paired) began immediately after the US terminated. The CSs used were a 1000-Hz 85-dB tone and an 84-dB click; their roles were counterbalanced. Over the next 2 days, each CS was presented for 2 min while the rats drank from a water bottle. The backward-paired CS was found to suppress licking more than the explicitly unpaired CS. This suppression was accompanied by an increase in defensive behavior (freezing and freeze/nod) and by a decrease in other activity. The suppression did not seem to be due to a maintained or enhanced CS-orienting response reflex, nor could it be attributed to an adventitiously reinforced interfering operant. The results support the presumption made in previous reports that the lick suppression evoked by a backward CS reflected one-trial backward excitatory fear conditioning. 相似文献
11.
W. Ronald Salafia Frederick W. Mis W. Scott Terry Robert S. Bartosiak Anthony P. Daston 《Learning & behavior》1973,1(2):109-115
The study involved three experiments. The first, a parametric investigation of nictitating membrane conditioning with eight constant intertrial intervals (ITIs) between 5 and 120 sec, orthogonal to interstimulus intervals (ISIs) of 250 and 750 msec plus three temporal conditioning control groups, revealed that performance improved rapidly with increasing ITI but stabilized at relatively low ITI values. At 750-msec ISI, a decrement in performance was found at 60-sec ITI. Experiment II, using constant ITIs of 45–75 sec in 5-sec steps, at 750-msec ISI confirmed the trend toward a performance decrement around 60 sec, although the trend was weak and highly variable. Experiment III evaluated the differences in performance between constant and variable ITI, using three ITI values and three conditions of variation at each value. Findings were discussed in terms of differences in conditioning resulting from both length and degree of variation of ITI and some subtle effects which may emerge only when constant ITIs are used. 相似文献
12.
Conditioned lick suppression in rats was used to explore the role of timing in trace conditioning. In Experiment 1, two groups of rats were exposed to pairings of a CS (CS1) with a US, under conditions in which the interstimulus interval (ISI) that separated CS1 offset and US onset was either 0 or 5 sec. Two additional groups were also exposed to the same CS1→US pairings with either a 0 or a 5-sec ISI, and then received “backward” second-order conditioning in which CS1 was immediately followed by a novel CS2 (i.e., CS1→CS2). A trace conditioning deficit was observed in that the CS1 conditioned with the 5-sec gap supported less excitatory responding than the CS1 conditioned with the 0-sec gap. However, CS2 elicited more conditioned responding in the group trained with the 5-sec CS1-US gap than in the group trained with the 0-sec CS1-US gap. Thus, the CS1-US interval had inverse effects on first- and second-order conditioned responding. Experiment 2 was conducted as a sensory preconditioning analogue to Experiment 1. In Experiment 2, rats received the CS1?CS2 pairings prior to the CS1→US pairings (in which CS1 was again conditioned with either a 0 or a 5-sec ISI). Experiment 2 showed a dissociation between first- and second-order conditioned responding similar to that observed in Experiment 1. These outcomes are not compatible with the view that differences in responding to CSs conditioned with different ISIs are mediated exclusively by differences in associative value. The results are discussed in the framework of the temporal coding hypothesis, according to which temporal relationships between events are encoded in elementary associations. 相似文献
13.
Two studies used a one-trial-a-day aversive conditioning procedure with rats as subjects to investigate the effects of a noise versus a light CS on conditioned freezing. Experiment 1 demonstrated that less conditioned freezing was elicited by the light, although the two CSs led to similar levels of freezing to the contextual cues of the conditioning chamber. Experiment 2 replicated these outcomes and showed that the manipulation of CS intensity produced results similar to those of modality, with the more intense CSs eliciting less freezing. The second experiment also determined that freezing to contextual cues resulted from context conditioning. According to the Rescorla-Wagner model, CSs that condition poorly should generate little competition with context conditioning. Since neither the modality nor intensity factor reliably influenced context conditioning, as measured by context-evoked freezing, the studies provide no support for the view that the effects on CS-evoked freezing represent differences in the strength of conditioning to the various stimuli. This finding raises the possibility that all of the CSs conditioned well but varied in their abilities to elicit freezing because they differed in terms of the form of defensive behavior under their control. 相似文献
14.
Juárez-Maldonado CE Ortega-Saavedra G Huichan-Olivares F Gómez-Romero J Cruz-Morales SE Arriaga-Ramírez JC 《Learning & behavior》2006,34(4):374-378
The serial position effect in Long-Evans rats was evaluated in two experiments. In Experiment 1, the effect in a group for
which an interstimulus interval (ISI) was introduced between items in a list of demonstrators was compared with that in a
group without an ISI. With an ISI, a recency effect was produced. In Experiment 2, a serial position effect group was compared
with four groups in which either the distinctiveness or the context of the middle item was changed, relative to the items
on either side of it. A von Restorff effect was produced when a rat from a different strain was used as a demonstrator in
Position 2. The results for Experiment 1 are discussed in relation to interstimulus effects in monkeys and those for Experiment
2 with respect to changes in the physical properties of middle items. 相似文献
15.
Steinmetz AB Skosnik PD Edwards CR Bolbecker AR Steinmetz JE Hetrick WP 《Learning & behavior》2011,39(4):358-370
Delay eye-blink conditioning is an associative learning task that can be utilized to probe the functional integrity of the
cerebellum and related neural circuits. Typically, a single interstimulus interval (ISI) is utilized, and the amplitude of
the conditioned response (CR) is the primary dependent variable. To study the timing of the CR, an ISI shift can be introduced
(e.g., shifting the ISI from 350 to 850 ms). In each phase, a conditioned stimulus (e.g., a 400- or 900-ms tone) coterminates
with a 50-ms corneal air puff unconditioned stimulus. The ability of a subject to adjust the CR to the changing ISI constitutes
a critical timing shift. The feasibility of this procedure was examined in healthy human participants (N = 58) using a bidirectional ISI shift procedure while cortical event-related brain potentials were measured. CR acquisition
was faster and the responses better timed when a short ISI was used. After the ISI shift, additional training was necessary
to allow asymptotic responding at the new ISI. Interestingly, auditory event-related potentials to the CR were not associated
with conditioning measures at either ISI. 相似文献
16.
In three experiments in which rats were used as subjects, we developed an extinction procedure using a Morris pool. The animals were trained to find a hidden platform located at a fixed position and were then given extinction trials in which the platform was removed from the pool. When training and extinction were carried out in the same context and time was allowed to elapse between extinction and test, spontaneous recovery of learning was observed. On the other hand, those rats that received extinction in a context different from the one used for training failed to show spontaneous recovery of learning when tested in the extinction context after an interval of 96 h. However, they did show renewal of spatial learning when tested in the training context. These results show that extinction in the spatial domain behaves like extinction in standard conditioning preparations. 相似文献
17.
Lynn J. Hammond 《Learning & behavior》1995,23(3):349-356
Three experiments were conducted to demonstrate that the place where an organism has been, before the organism is moved to a place with aversive consequences, can also become aversive through classical conditioning. In Experiment 1, two groups of 8 mice were exposed to three different contexts in succession, with a single shock occurring in the third context. The distal context was a putative 3-min conditioned stimulus (CS) for freezing; the second context was a delay manipulation; and the unconditioned stimulus (US) occurred in the proximal context. The group delayed for 15 sec showed significantly more freezing to the distal CS context than did the group delayed for 3 h. In a second experiment, conditioning to the distal context was demonstrated with a discrimination procedure for 8 more mice by using two different distal contexts as CS+ and CS? for the proximal context with shock. On CS+ days, 3 min of exposure to the distal context was followed within 5 sec by placement in the proximal box where shock occurred, whereas on CS? days, exposure to a second distal context was followed immediately by return to the home cage. Very strong differences in freezing between the CS+ and CS? distal contexts were found in all 8 mice after 14 days of conditioning. In a third experiment, the discriminative procedure was repeated for 9 more mice, with two changes. More objective stabilometertype activity measures were substituted for observed freezing, and, in addition to the CS+ and CS? distal context trials, each mouse was also exposed to a third discriminative distal context, which was followed by 15 min in a delay chamber followed by shock in the proximal context. This discrimination procedure with the activity suppression measure again resulted in significant differences between the contexts. The CS+ context and the context followed by a 15-min delay did not differ, but both of them differed from the CS? context. 相似文献
18.
W. Ronald Salafia Richard W. Lambert Karen C. Host Nicolas L. Chiaia Julio J. Ramirez 《Learning & behavior》1980,8(1):85-91
In three experiments, the nictitating membrane response of rabbits was conditioned for 10 daily sessions at interstimulus intervals (ISIs) ranging from 48 to 125 msec, followed by a shift to 250 msec for 5 days. At tested ISIs shorter than 67 msec, there was no evidence of conditioning, and postshift performance revealed neither facilitation nor interference as a result of the first 10 conditioning sessions. Postshift performance of groups conditioned at preshift ISIs of 67 msec or longer revealed a gradient of increasing savings with increasing ISI. One of the groups in Experiment 1, initially conditioned at 250 msec ISI and then shifted to 48 msec, exhibited extinction of the previously well-conditioned response. Analysis of CR-onset latencies substantiated the absence of associative effects at very short ISIs. It was concluded that there is a temporal limit below which classical conditioning of the nictitating membrane response of rabbits employing forward CS-US pairing does not occur. 相似文献
19.
In four experiments, each using a single conditioning trial, rats avoided a light more than a saccharin solution after these stimuli had been paired with footshock, whereas saccharin was avoided more than the light after these stimuli had been paired with lithium injection. The use of a single conditioning trial precludes possible US-induced differential orientations from influencing which stimuli will be associated on the conditioning trial. This cue-consequence specificity effect was obtained even when subjects conditioned with lithium received a non-contingent footshock prior to the test session, and when subjects conditioned with footshock received a noncontingent lithium injection before testing (Experiments 2–4). Weak aversions to the light in rats given a light-lithium pairing and noncontingent footshock and to the saccharin in subjects that received a saccharin-footshock pairing and noncontingent lithium administration were obtained in Experiment 2. However, these weak aversions were not obtained when subjects were given three nonreinforced exposures to the test chamber before the test session (Experiments 3 and 4). These results indicate that US-induced differential orientations do not mediate the cue-consequence effect in aversion learning. 相似文献
20.
Mary Ann Balaz Sharon Capra Wesley J. Kasprow Ralph R. Miller 《Learning & behavior》1982,10(2):242-248
Previous research in our laboratory has found superior performance when classically conditioned responses are observed in the training context as opposed to outside it, even when direct context-US associations have been minimized by either the choice of conditioning parameters or extinction to the context. The present experiment used latent inhibition of the conditioning context as an alternative method of examining contextual cue effects in the absence of appreciable direct context-US associations. Water-deprived rats received tone-footshock pairings in one of two distinctly different apparatuses, but all were tested in a common apparatus. Animals conditioned in the test enclosure displayed more lick suppression than those conditioned outside the test enclosure. Other animals tested without the tone present also exhibited more suppression if conditioning had occurred in the test context rather than outside it, indicating that direct associations between the conditioning context and shock had been formed. However, when formation of direct associations to the conditioning context was attenuated in additional animals through extensive preexposure to the context prior to conditioning, more suppression to the tone was still seen when conditioning had occurred in the test context rather than outside it. These results add support to the position that the training context augments recall even when direct associations between the context and the US are attenuated. The phenomenon is discussed in terms of facilitated retrieval of nominal CS-US associations, configural retrieval cues, and conditional discriminations. 相似文献