共查询到17条相似文献，搜索用时 239 毫秒
1.
目的:应用彩色多普勒超声诊断仪对已婚女性不孕症患者,开展月经中前期双侧卵巢卵泡发育情况的监测,排除子宫、卵巢病变因素,从而达到提高受孕率的目的。方法:患者适度充盈膀胱,从月经周期的第11天开始监测双侧卵巢卵泡发育情况,在子宫、卵巢位置作纵、横、斜等切面扫查。结果:卵泡直径在20mm以上者为优势卵泡,可发生排卵现象。<16mm为劣势卵泡,不发生排卵。结论:当卵泡达到≥20mm时,可指导不孕症患者进行受孕准备。 相似文献
2.
哺乳动物卵泡的生长和发育过程中,大多数卵泡发生闭锁,只有少数卵泡能发育成熟并排卵,卵泡颗粒细胞的凋亡将诱发卵泡闭锁.FoxO3a是调控细胞生长和凋亡的重要转录因子之一,在猪卵巢颗粒细胞中特异性表达.该试验用机械法分离卵泡,按直径大小分为:小卵泡(1.5—3mm)、中卵泡(3—5 mm)和大卵泡(≧5 mm)3组,分别统计健康卵泡和闭锁卵泡所占比率,分离颗粒细胞(pGC).用AnnexinⅤ-FITC/PI双染法流式细胞术检测pGC存活率,Western blot检测pGC内FoxO3a表达水平.结果表明:随卵泡直径的增大,闭锁卵泡的比率逐渐降低(P<0.05),健康卵泡的比率增加(P<0.05);pGC存活率升高(P<0.05);pGC内FoxO3a表达水平逐渐升高(P<0.05).可见:FoxO3a转录因子可能通过抑制卵泡颗粒细胞的凋亡,从而调节猪卵泡的生长和闭锁. 相似文献
3.
目的：探讨超声监测不孕症患者卵泡演变及其临床意义.方法：采用ALKOAα6及ALKOA-3500彩色多普勒超声诊断仪,应用阴道和腹部及会阴超声联合应用的探测方法,对82例不孕症患者卵泡实施动态监测一个月经周期内卵泡的数量、大小、回声表现等变化,及时提供临床排卵信息并指导临床治疗和生殖辅助;随访3个月,了解受孕情况.结果：82例患者中,57例在月经周期的10-36d有排卵、14例无优势卵泡发育、6例卵泡成熟后未排逐渐变小、3例卵泡囊肿（其中1例黄素化）及2例仅做1次无结果.有排卵患者中8例成功受孕,其中4例合并子宫肌瘤、4例合并卵巢囊肿;不孕患者中有5例合并双侧或一侧输卵管不通,8例有盆腔炎及附件炎病史,余例为其他原因引起的不孕;无卵泡发育及卵泡发育缓慢患者中6例患者通过药物治疗后成功受孕.结论：超声监测不孕症患者卵泡演变可及时提供临床排卵信息,对临床有效治疗不孕症具有重要指导价值. 相似文献
4.
徐苓 《新课程学习(社会综合)》2014,(3):51-51
女性为何经历更年期
要从容面对更年期,先就要了解它。女人走过这一生,发育后有了月经,也会经历最后一次经期,然后绝经。通常我们把绝经前后这一段时期叫做更年期。绝经取决于女性的性腺——卵巢,卵巢里有很多卵泡,一方面要排卵,负责生育,另一方面要分泌性激素。女孩在妈妈肚子里时,卵泡最多,有700多万个,出生后就花去好几百万,第一次来月经时还剩30万～40万,往后每次月经就会排一次卵。卵泡不会再生,只会越来越少,卵泡耗竭,卵巢的寿命也就基本结束了,女人就会绝经。可以说绝经早晚决定于你有多少卵泡和你消耗卵泡的速度。 相似文献
5.
范伟荣 《金华职业技术学院学报》2013,(6):74-77
目的：探讨不同止血方法对腹腔镜卵巢囊肿剔除术后年轻患者卵巢储备功能的影响。方法：将2009年12月至2011年12月因单侧良性卵巢囊肿且年龄≤35岁的住院患者83例随机分为缝合组与电凝组．两组分别于术前、术后,1、6个月后第一次月经的第2-5天检测血清雌二醇（E：）、卵泡刺激素（FSH）及黄体生成素（LH）水平;阴道彩超检测窦卵泡数（AFC）和卵巢间质动脉血流的收缩期峰值（PSV）;以两者结合判定卵巢储备功能。结果：术前激素水平两组间差异无统计学意义（P〉0．05）;术后1、6个月E2、FSH水平与术前比较,缝合组无差异（P〉0．05）、电凝组有差异（P〈0．05）、两组间比较有统计学意义（P〈0．05）,LH水平差异无统计学意义（P〉0．05）;术后1、6个月AFC、PSV水平差异与术前比较,缝合组组内、组间均无统计学意义（P〉0．05）,电凝组组内、组间均有统计学意义;术后共发生卵巢储备功能下降者缝合组10．8％,电凝组15.2％。结论：腹腔镜下卵巢囊肿剔除术两种止血方法对卵巢储备功能均有影响,电凝止血法较单纯缝合止血法所致卵巢储备功能下降更加明显。 相似文献
6.
张海玲 《中小学实验与装备》2009,19(5):15-15
1小制作的好处
1．1小制作能培养学生注意力集中
一个人注意力高度集中,才能提高办事效率。在进行小制作的过程中,学生容易把与制作内容无关的事情都抛开,做到心无杂念,并把手、脑、眼协调起来,共同工作。这些器官在不知不觉中得到的锻炼。动手和思维能力也能得到有效培养。同时注意力高度集中的品质也得到充分锻炼。例如学生在制作通电螺线管时。要让直径只有1mm的铜芯线紧密排绕在5mm的铁丝上,就要求学生得注意力集中,否则容易出现排绕不紧密的现象。 相似文献
7.
张海玲 《中小学实验与装备》2009,(5):15-15
1小制作的好处
1．1小制作能培养学生注意力集中
一个人注意力高度集中,才能提高办事效率。在进行小制作的过程中,学生容易把与制作内容无关的事情都抛开,做到心无杂念,并把手、脑、眼协调起来,共同工作。这些器官在不知不觉中得到的锻炼。动手和思维能力也能得到有效培养。同时注意力高度集中的品质也得到充分锻炼。例如学生在制作通电螺线管时。要让直径只有1mm的铜芯线紧密排绕在5mm的铁丝上,就要求学生得注意力集中,否则容易出现排绕不紧密的现象。 相似文献
8.
黄笠逍 《河北北方学院学报(医学版)》2000,(3)
自70年代以来,异位妊娠发病明显增加。输卵管切除会对生育带来严影响。异位妊娠保守治疗始于1953年的输卵管切开术。保守治疗的关键是早期诊断,目前主要诊断方法有:HCG检测的数值和倍增时间低于正常妊娠;B超显示未孕子宫、附件包块及异位妊娠破裂时的盆腔游离液体;孕酮(P4)测定多数浓度<15ng/ml;腹腔镜可以直观观察病变位置、大小、是否破裂、出血等。异位妊娠保守治疗的目的在于完全破坏绒毛组织,终止异位妊娠,减小机体损伤,最大限度地保留生育功能。与发病程度、病变部位及保守治疗方法有关。如希望保留生育功能,妊娠输卵管未破裂,血液动力学稳定。血HCG<2,500mIU,附件包块<3cm可以保守治疗。具体方法有:1、输卵管切开术:即切开输卵管,取出妊娠组织,开放输卵管切口二期愈合。2、输卵管切开缝合术:与上相似,但缝合输卵管切口。3、节段切除术:用于峡部妊娠,及已破裂但病情稳定者。把包含妊娠组织在内的输卵管段连同系膜切除。4、伞端挤出术。5、腹腔镜:可诊断、手术及局部药物注射,如氨甲喋呤、KCL、高渗糖、前列醇等。6、氨甲喋呤(MTX)是当前首选的保守治疗方法之一。全身用药有以下几种方案:(1)15mg/d,肌注,5d为一疗程,两疗程问可停药48h;(2)1mg/kg/d,肌注,隔日一次,共4次;每次注射MTX后20h给leucovorin 15mg口服解救;(3)疗程的1,3,5,7日肌注MTX1.0mg/kg,2,4,6,8日肌注Citrovorum因子(CF)0.1mg/kg。还可直接向妊娠囊内注药。7.前列腺素:在腹腔镜的引导下,经腹穿刺进入妊娠输卵管壁及卵巢,注入PGF2a,可同时肌注合成PGF2a,前列腺素治疗有心血管副作用,不宜卵巢内用药。8.高渗糖:经腹穿刺,向妊娠输卵管内注入50％的葡萄糖10～20ml,高渗糖治疗安全有效,未见副作用报道。除了维持输卵管的通透性外,还能够保持其拾卵、运卵功能。9.氯化钾:经腹穿刺,向妊娠输卵管内注入15％～20％的氯化钾0.5ml～5ml。10.RU486是终止早孕的药物,也可用于异位妊娠。异位妊娠保守治疗监测与评估包括B-hCG、B超、临床表现及生育功能。如HCG持续不降或升高,B超显示盆腔大量积液,腹痛加剧等提示病情恶化,应及时开腹手术。 相似文献
9.
Objective: We dynamically measured serum inhibin B and estradiol in the early stage of hormonal stimulation to predict the ovarian response in in vitro fertilization (IVF) treatment. Methods: A total of 57 patients (<40 years of age) who un-derwent the first cycle of long protocol IVF or introcytoplasmic sperm injection (ICSI) treatment were included. Serum inhibin B, estradioi, follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels were measured four times: (i) on Day 3 of the menstrual cycle (basal); (2) on the day before the first administration of gonadotrophin (Gn) (Day 0); (3) on Day 1 of Gn therapy; and (4) on Day 5 of Gn therapy. Comparisons of these measurements with ovarian responses and pregnancy outcomes were made and analyzed statistically. Results: (1) On Day 1 and Day 5 of recombinant FSH (rFSH) stimulation, ovarian response, i.e., numbers of follicles, oocytes, fertilized oocytes, and embryos, had a positive correlation (rS=0.46～0.61, P=0.000) with raised inhibin B and estradiol concentrations, but a negative correlation (rS=-0.67～-0.38, P=0.000 or P<0.01) with total rFSH dose and total days ofrFSH stimulation. (2) No significant variation (P>0.05) between the pregnant and non-pregnant groups on the basis of mean age or on all hormone concentrations at four times of the IVF cycle was observed. However, all the seven patients aged >35 years did not reach pregnancy. Conclusions: (1) Serum inhibin B and estradiol concentrations obtained shortly after Gn therapy may offer an accurate and early prediction of ovarian response; (2) Low levels of serum inhibin B and estradiol obtained shortly after Gn stimulation indicate the need for a longer period of Gn treatment and a higher daily dosage; (3) No obvious pregnancy difference among patients of age <35 years was found; however, IVF pregnancy outcome is significantly lower in women of age >35 years. 相似文献
10.
本文利用微量自动泵给恒河猴卵巢黄体连续注射催产素（Oxytocin，10miu／h）的局部在体实验，对催产素（OT）的溶黄体作用及机理进行了初步的研究．结果显示，OT注射后第2天其外周血的孕酮激素水平开始下降，而雌二醇（E2）则在处理后第总天开始下降（P＜0．05）同时．OT的局部注射还能引起恒河猴月经周期黄体期明显缩短，使下一月经周期提前开始（P＜0．01）．实验表明，催产素（OT）在卵巢溶黄体过程中起着重要的作用，卵巢溶黄体作用的发生是通过其自身的分泌机制调节实现． 相似文献
11.
The development of ovarian follicular cells is controlled by multiple circulating and local hormones and factors, including
follicle-stimulating hormone (FSH) and epidermal growth factor (EGF). In this study, the stage-specific effect of EGF on FSH-induced
proliferation of granulosa cells was evaluated in the ovarian follicles of egg-laying chickens. Results showed that EGF and its receptor (EGFR) mRNAs displayed a high expression in granulosa cells from the prehierarchical follicles, including the large white follicle
(LWF) and small yellow follicle (SYF), and thereafter the expression decreased markedly to the stage of the largest preovulatory
follicle. SYF represents a turning point of EGF/EGFR mRNA expression during follicle selection. Subsequently the granulosa cells from SYF were cultured to reveal the mediation
of EGF in FSH action. Cell proliferation was remarkably increased by treatment with either EGF or FSH (0.1–100 ng/ml). This
result was confirmed by elevated proliferating cell nuclear antigen (PCNA) expression and decreased cell apoptosis. Furthermore,
EGF-induced cell proliferation was accompanied by increased mRNA expressions of EGFR, FSH receptor, and the cell cycle-regulating
genes (cyclins D1 and E1, cyclin-dependent kinases 2 and 6) as well as decreased expression of luteinizing hormone receptor
mRNA. However, the EGF or FSH-elicited effect was reversed by simultaneous treatment with an EGFR inhibitor AG1478. In conclusion,
EGF and EGFR expressions manifested stage-specific changes during follicular development and EGF mediated FSH-induced cell
proliferation and retarded cell differentiation in the prehierarchical follicles. These expressions thus stimulated follicular
growth before selection in the egg-laying chicken. 相似文献
12.
通过分析影响人工授精的各种因素寻求提高临床妊娠率的方法.方法:对行IUI治疗的不孕症夫妇148例共242个周期,分析患者的年龄、促排卵方案、HCG注射日子宫内膜厚度及类型、每周期内IUI次数、IUI周期数、处理后前向运动精子总数对IUI妊娠率的影响.结果:女方年龄、助孕周期数、HCG注射日子宫内膜厚度及类型、精液处理后的前向运动精子总数与IUI妊娠率有关.结论:女方年龄、助孕周期数、HCG注射日子宫内膜厚度及类型、精液处理后的前向运动精子总数影响IUI妊娠率,一周期内双次IUI、促排卵药物使用无法提高IUI妊娠率. 相似文献
13.
银杏叶愈伤组织增殖过程中生理生化特性的研究 总被引：2，自引：0，他引：2
本文系统研究了银杏叶愈伤组织培养细胞的生长周期,并对培养过程中细胞内的可溶性蛋白的含量,过氧化物酶、苯丙氨酸解氨酶活性的变化以及银杏总黄酮的含量进行了测定,以期为银杏细胞的大规模培养积累数据。 相似文献
14.
Stephen H. Davidoff 《科学教学研究杂志》1969,6(4):349-357
Sixth grade children representing each of the eight Philadelphia Public School Districts attended morning sessions at the Franklin Institute one day a week for a seven-week cycle. Each weekday, a different pair of schools participated, thereby, involving the same 10 schools each week for the cycle. The two program cycles involved 700 children and 20 teachers from 20 different schools. The first cycle was used as a “tooling-up period.” During this time instruments were developed. During the second cycle measurements of science information and student interactions were made. 相似文献
15.
恒河猴头骨非测量性状指标观察 总被引：1，自引：0，他引：1
观察了24例实验恒河猴(Macaca mulatta)完整头骨的近100项非测量性状.结果表明,颅形以楔形为主(41.67%),其次为盾形(29.17%);眶形多为圆形(58.33%);枕骨大孔形状较多,以五角形(29.17%)和菱形(20.83%)多见;翼区缝结构绝大多数为额颞型(79.17%).枕外隆凸显著(41.67%).＞12岁时颅顶缝趋向愈合,＜12岁猴矢状缝各段以深波形和锯齿形居多,冠状缝和人字缝各段主要为微波形.颧颞孔一般左右各一个(83.33%),颧面孔一般左右各一个(45.83%),两侧俱缺的较常见(33.33%),眶下孔以左右各3个最常见(41.67%). 相似文献
16.
We examined the ontogeny of the infant rhesus monkey's defensive behaviors and the ability to modulate them in response to specific environmental cues. Rhesus infants in 4 age groups (N = 8 per group) were briefly separated from their mothers and tested under 3 conditions: alone, in the presence of a human who averted his gaze, and in the presence of a human staring at them. Infants as young as 0 to 2 weeks displayed defensive behaviors but did not selectively respond to the human's presence or direction of gaze. By 9 to 12 weeks of age, infants modulated their responses in relation to the parameters of the threat. At this age, infant rhesus monkeys undergo cognitive and emotional changes associated with brain development similar to those in human infants 7 to 12 months old. This also is the time when human infants engage in complex emotional and behavioral responses to threatening situations. Understanding the development and expression of defensive behaviors in infant monkeys should be applicable to similar issues in emotional development of human infants. 相似文献
17.
通过观察恒河猴血传急性感染猪尾猴疟原虫的过程发现,对宿主切脾后,原虫血症迅速升高而达到一个血症高峰。随着幼稚红细胞的出现,虫血症急剧下降而出现危象期,外周血T淋巴细胞数量急剧增加;红细胞免疫功能升高,接种后宿主疟疾抗体出现较晚,切脾可使IFA抗体滴度暂时下降,在危象期前一天和危象期中TFA抗体滴度急剧升高。 相似文献