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1.
In social networking services (SNSs), users’ unclear understanding of the large and invisible audience increases the chances of online turbulence, which is a key source of SNS-induced stress. This growing phenomenon has gained increasing attention in academia and industry due to the undesirable consequences for users and SNS platforms. In this study, we draw from the transactional model of stress to examine how audience management strategies impact online turbulence and lead to neglected unintended audience concern and lurking. We also investigate the role of self-monitoring as a stress inhibitor. We test our model with data collected from 301 SNS users. The results show that the four types of audience management strategies have different effects on online turbulence, which significantly impacts neglected unintended audience concern especially when users have high self-monitoring skills. We believe that this work contributes, both from scientific and practical standpoints, to the understanding of the interventions and stressful responses of online turbulence in SNSs. 相似文献
2.
R. B. Bhogade A. N. Suryakar N. G. Joshi R. Y. Patil 《Indian journal of clinical biochemistry : IJCB》2008,23(3):233-237
Hemodialysis represents a chronic stress status for its recipients. Many hypotheses state that this may be associated with
oxidative stress. Thus, there may be deficiency of antioxidants like erythrocytic superoxide dismutase, catalase, vitamin
E or increased generation of free radicals like superoxide anions. A study was carried out to investigate oxidant and antioxidant
status in chronic renal failure patients undergoing hemodialysis and effect of vitamin E supplementation on these two status.
Blood samples were collected from patients before and after hemodialysis and from controls. The samples were analyzed for
quantitation of MDA as index of lipid peroxide, nitric oxide, vitamin E, vitamin C and enzymatic antioxidants namely erythrocyte
SOD and catalase. As compared to controls, the levels of serum MDA were significantly increased and activities of erythrocyte
SOD and catalase, levels of serum nitric oxide, serum vitamin E and plasma vitamin C were significantly decreased both before
and after hemodialysis. The efficiency of vitamin E therapy in hemodialysis patients was assessed by re-evaluating oxidant
and antioxidant status of same patients after supplementation of vitamin E. Vitamin E supplementation caused decrease in serum
MDA and increase in levels of serum nitric oxide, vitamin E, vitamin C and activities of erythrocytic SOD and catalase. Our
results suggest the presence of oxidative stress and the possible preventive role of vitamin E therapy in hemodialysis patients. 相似文献
3.
Rebecca Soffe Sara Baratchi Shi-Yang Tang Arnan Mitchell Peter McIntyre Khashayar Khoshmanesh 《Biomicrofluidics》2016,10(2)
Microfluidic platforms enable a variety of physical or chemical stimulation of single or multiple cells to be examined and monitored in real-time. To date, intracellular calcium signalling research is, however, predominantly focused on observing the response of cells to a single mode of stimulation; consequently, the sensitising/desensitising of cell responses under concurrent stimuli is not well studied. In this paper, we provide an extended Discontinuous Dielectrophoresis procedure to investigate the sensitising of chemical stimulation, over an extensive range of shear stress, up to 63 dyn/cm2, which encompasses shear stresses experienced in the arterial and venus systems (10 to 60 dyn/cm2). Furthermore, the TRPV4-selective agonist GSK1016790A, a form of chemical stimulation, did not influence the ability of the cells'' to remain immobilised under high levels of shear stress; thus, enabling us to investigate shear stress stimulation on agonism. Our experiments revealed that shear stress sensitises GSK1016790A-evoked intracellular calcium signalling of cells in a shear-stimulus dependent manner, as observed through a reduction in the cellular response time and an increase in the pharmacological efficacy. Consequently, suggesting that the role of TRPV4 may be underestimated in endothelial cells—which experience high levels of shear stress. This study highlights the importance of conducting studies at high levels of shear stress. Additionally, our approach will be valuable for examining the effect of high levels of shear on different cell types under different conditions, as presented here for agonist activation. 相似文献
4.
S. D. Walwadkar A. N. Suryakar R. V. Katkam K. M. Kumbar R. D. Ankush 《Indian journal of clinical biochemistry : IJCB》2006,21(2):134-137
Generation of reactive oxygen species is an important factor in the development and maintenance of rheumatoid arthritis (RA)
in humans. This study was undertaken to investigate interplay among oxidants, antioxidants and pathogenesis of Rheumatoid
arthritis. Serum levels of lipid peroxides, nitric oxide, vitamin E and ratio of calcium/phosphorus in RA patients were determined
and compared with normal healthy controls. Significant increases in lipid peroxides (p<0.001) and nitric oxide (p<0.001) levels
were found in patients presenting with RA as compared to controls. Whereas significant decrease in vitamin E (P<0.001) and
calcium/phosphorus ratio (p<0.001) were found in Rheumatoid arthritis patients as compared to controls. Positive correlation
was found between lipid peroxides and nitric oxide as well as between vitamin E and calcium. While lipid peroxides and nitric
oxide were correlated negatively with vitamin E. whereas negative correlation was observed between MDA and Calcium/Phosphorus
ratio in patients with rheumatoid arthritis. Our findings suggest that there is a close association between bone loss and
oxidative threat in patients presenting with Rheumatoid arthritis. 相似文献
5.
鲁索(Ronald Rousseau)是世界著名的情报计量学家、数学家,并于2001年获得了信息计量学和科学计量学的最高奖——普赖斯奖。本文运用文献计量学、科学计量学、知识可视化的方法和技术,以WoS数据库论文数据为基础,对鲁索的学术论文及其成就影响进行定量分析,以期明确鲁索的主要学术领域及其与中国的学术交往。通过对其论文发表时间、期刊分布、被引频次、共词分析发现,鲁索的主要研究方向在情报计量学和h指数方面。通过对鲁索与中国的学术交往分析发现,鲁索与中国的科研机构及学者保持着长期密切的合作关系。 相似文献
6.
Enterprise Social Media Platforms (ESMPs) are arenas for self-presentation where employees construct, co-create, and maintain an online image among their colleagues. This study systemically evaluated the current literature to understand the potential of ESMPs in influencing employees’ impression management strategies from the affordance perspective. Drawing from a focused review of the literature on ESMPs’ affordances and impression management, this paper reclassified employees’ impression management strategies in the context of ESMPs. It proposes a conceptual framework that captures the complex relationship between ESMPs’ affordances and employees’ various impression management strategies. The framework highlights that ESMPs’ affordances affect employees’ impression management strategies, both positively and negatively, and proposes the contingent effects of individual motives and boundary management on the relationship between affordances and employees’ impression management strategies. Our literature review and proposed framework provide a useful basis for future studies on impression management on ESMPs. Our framework also helps employees manage impressions strategically and managers and ESMPs’ developers to fulfil ESMPs’ potential by understanding how affordance affects impression management strategies. 相似文献
7.
基于对528名知识员工的两阶段调查,探讨了角色压力对生活满意度的影响、家庭干涉工作的中介作用以及社会支持的调节作用。层次回归与调节路径分析结果表明:知识员工角色压力对其生活满意度不仅可以产生直接消极影响,而且当社会支持较低时,还会通过家庭干涉工作的完全中介作用产生间接消极影响;该作用机制具体表现为被调节的中介效应,即家庭干涉工作在角色压力与生活满意度之间的中介作用受到社会支持的负向调节,在较高社会支持水平下,家庭干涉工作对生活满意度的影响将不再显著,并且角色压力也不再通过家庭干涉工作的中介作用对生活满意度产生间接影响。 相似文献
8.
本文通过实证调研工作压力和社会支持对高校教师工作绩效的影响后发现:(1)高校教师的工作压力较高,特别是高工作要求低收入、工作量大工作时间长而产生的压力;教师获得的社会支持较多来源于家人和朋友,来自上级和组织的支持较少;社会支持形式多为情感支持,工具支持和信息支持较少。(2)五种压力源与压力症状具有显著正相关;工作量大时间长压力源与关系绩效显著负相关;高工作要求低收入、工作量大时间长与任务绩效显著负相关。(3)工作压力源、社会支持对压力症状具有一定的预测作用, 压力症状是工作压力源与社会支持作用于工作绩效的中介变量。(4)社会支持对关系绩效有显著直接影响,对任务绩效没显著直接影响。文章最后根据实证分析结果,从学校、主管领导、家人、朋友和自身等五个方面提出高校教师压力管理和社会支持对策建议。 相似文献
9.
Recent information and cybersecurity research have focused on improving individuals’ security compliance behavior. However, improved security performance remains a challenge since individuals often fail to comply with security best practices. In this study, we investigate a new individual cybersecurity compliance behavior model proposed by Donalds and Osei-Bryson (2017). Specifically, we investigate the influence of individual decision styles on their cybersecurity compliance behavior and other antecedents of such behavior. To empirically validate the hypotheses in the Donalds & Osei-Bryson model, we used data collected from 248 individuals and then use multiple regression to examine the assertions of the model. Our findings confirm that individual’s decision styles, specifically, dominant orientation and dominant decision style, influence their individual cybersecurity compliance behavior and other antecedents of such behavior. Our research offers new dimensions for investigating individual cybersecurity compliance behavior and new insights into factors that may influence individual’s cybersecurity compliance behavior. 相似文献
10.
The successful accomplishment of information systems development (ISD) activities is reliant on the efforts of developers, who are largely responsible for creating the required system artefacts. Developers encounter numerous obstacles in their efforts to successfully complete activities, such as the need to develop software within highly-complex broad-ranging projects. These problems increase levels of stress, which subsequently affect developers’ ability to self-regulate their feelings and understanding. However, only scant attention has been paid to their personal skills and competency in overcoming these issues. This study therefore aimed to bridge this gap by exploring the impact of developers’ emotional intelligence on stress, trust, and performance. Our empirical results show that emotional intelligence mitigates stress and fosters trust among software developers working on information system projects. Additionally, role ambiguity increases the effect of stress on performance. 相似文献
11.
Surekha Bhat Guruprasad Rao K. Dilip Murthy P. Gopalakrishna Bhat 《Indian journal of clinical biochemistry : IJCB》2008,23(2):191-194
High ambient temperature has been reported to increase oxidative stress by increasing lipid peroxidation and decreasing antioxidant
defence in transition dairy cows. It is also known to cause an increase in plasma cortisol levels in goats, European hedgehog
and human volunteers. High levels of glucocorticoids have been reported to decrease blood glutathione and erythrocyte superoxide
dismutase activity in rats. Although institutional animal houses in research laboratories of developed countries maintain
animals in air-conditioned rooms at constant temperature, the same is not true of animal houses in the developing countries
especially those belonging to smaller institutions and this could affect the results of the experiments being conducted on
these animals. The present research study was done to assess the effects of seasonal variations on the status of erythrocyte
oxidative damage, antioxidant defence and plasma cortisol levels in adult female Wistar rats. Rats were kept in their home
cages and were left in non-air-conditioned procedure rooms in two different seasons, Hot season (March-May) and Cool season
(June to September). Erythrocyte Thiobarbituric acid reactive substances and plasma cortisol levels were significantly increased
in rats exposed to high ambient temperature and humidity of the hot season as compared to the rats of the cool season. Erythrocyte
reduced glutathione levels, erythrocyte glutathione peroxidase and superoxide dismutase activities were significantly decreased
in the hot season group of rats. The results of our experiments showed that exposure of adult female Wistar rats to high ambient
temperature and humidity of the hot season increases neuroendocrine stress, oxidative stress and decreases antioxidant defence
in them. 相似文献
12.
Organizations increasingly implement processes-oriented setups like value stream production. Whereas this transition may bring many advantages on an organizational level, related studies show that shop floor workers feel less able to maintain close contact with others and exchange awareness cues. Their diminished social connectedness has consequences on the personal (e.g., reduced satisfaction) and organizational (reduced efficiency) level. The current wave of digitization brings ample opportunities for companies to bring their employees closer together again. In order to identify such opportunities, we have studied the shop floor production practices of an automotive OEM (original equipment manufacturer) for nearly two years. Following a scenario-based action design science approach, we have developed problem and activity scenarios as well as a prototype that helps the workers to improve their social connectedness in three different scenarios. Eight weeks of use demonstrated the prototype’s positive impact on the employees’ social connectedness by allowing for social appraisal and by improving their sense of sharing and involvement. Our results show which information technology (IT) design elements can contribute to social connectedness on the shop floor. 相似文献
13.
《Information processing & management》2022,59(5):103011
Nowadays, stress has become a growing problem for society due to its high impact on individuals but also on health care systems and companies. In order to overcome this problem, early detection of stress is a key factor. Previous studies have shown the effectiveness of text analysis in the detection of sentiment, emotion, and mental illness. However, existing solutions for stress detection from text are focused on a specific corpus. There is still a lack of well-validated methods that provide good results in different datasets. We aim to advance state of the art by proposing a method to detect stress in textual data and evaluating it using multiple public English datasets. The proposed approach combines lexicon-based features with distributional representations to enhance classification performance. To help organize features for stress detection in text, we propose a lexicon-based feature framework that exploits affective, syntactic, social, and topic-related features. Also, three different word embedding techniques are studied for exploiting distributional representation. Our approach has been implemented with three machine learning models that have been evaluated in terms of performance through several experiments. This evaluation has been conducted using three public English datasets and provides a baseline for other researchers. The obtained results identify the combination of FastText embeddings with a selection of lexicon-based features as the best-performing model, achieving F-scores above 80%. 相似文献
14.
Rizwan Ahmad Anil K. Tripathi Payal Tripathi Ranjana Singh Sushma Singh Raj K. Singh 《Indian journal of clinical biochemistry : IJCB》2008,23(4):328-333
Chronic myeloid leukemia is a myeloproliferative disorder with a unique rearrangement, the Philadelphia chromosome. Oxidative
stress, a pervasive condition of an increased number of reactive oxygen species, is now recognized to be prominent feature
of various diseases and their progression. Thus antioxidants, which control the oxidative stress state, represent a major
line of defense regulating overall true state of health. The relationship between antioxidants status and levels of well-known
markers of oxidative stress that are measured as lipid peroxides and oxidized proteins reflect better health indices and postures.
The aim of this study was to evaluate the role of oxidative stress in pathophysiology of Chronic myeloid leukemia by measuring
the circulating plasma lipid peroxide levels in terms of malonyldialdehyde, total lipid hydroperoxide and oxidized proteins
as protein carbonyl whereas antioxidant status were estimated in terms of reduced glutathione and total thiol in plasma of
Chronic myeloid leukemia patients. The present study included 47 Chronic myeloid leukemia patients and 20 age-and sex-matched
healthy subjects. Out of 47 Chronic myeloid leukemia patients, 31 were in chronic phase (CML-CP) and 16 in accelerated phase
(CML-AP). The median age of Chronic myeloid leukemia patients was 33 years and that of controls was 32 years. Oxidative stress
and antioxidant status in plasma were evaluated by spectrophotometric procedures. There was a significant increase (p<0.05)
in plasma malonyldialdehyde, total lipid hydroperoxide and protein carbonyl levels in Chronic myeloid leukemia patients as
compared to healthy subjects. Our results also showed that plasma malonyldialdehyde and protein carbonyl levels were markedly
elevated (p<0.05) in both chronic phase (CML-CP) and accelerated phase (CML-AP) as compared to healthy volunteers. Antioxidant
status was found to be significantly decreased (p<0.05) in Chronic myeloid leukemia patients and its phases as compared to
healthy participants. It could be concluded that oxidative stress may be associated with the pathophysiology of Chronic myeloid
leukemia. 相似文献
15.
P. Subash Prema Gurumurthy A. Sarasabharathi K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2010,25(2):127-132
Establishment of non-invasive urinary biomarker for the early prediction of essential hypertension (EH) is important. We evaluated
whether estimation of urinary DNA, serves as a marker to predict the extent of cellular oxidative stress in essential hypertension.
A total of 180 South Indian subjects aged 30–65 were recruited for the study. Of these hypertensive subjects investigated,
30 were newly diagnosed and were not on any antihypertensive drugs, but had systolic blood pressure 140–160 mmHg and diastolic
blood pressure 95–100 mmHg and 75 hypertensive patients who already on drug therapy for one year and 75 were South Indian
normotensive healthy controls with blood pressure ≤ 120/80 mmHg. The 8-OHdG level in urine was significantly increased in
hypertensive patients (both newly diagnosed and who already on drug therapy) compared with control group. The significant
increase in 8-OHdG was observed in newly diagnosed hypertensive patients compared with hypertensive patients who already on
drug therapy. There was a significant decrease in serum TAS value in essential hypertensive group when compared to control
group. The urinary 8-OHdG was independently correlated with serum TAS. Decreased TAS levels, which reflect to increased oxidative
stress, may be the reason of increased urinary 8-OHdG in South Indian hypertensive patients. Our preliminary data suggest
that the competitive ELISA for 8-OHdG appears to be a simple method for quantifying the extent of oxidative stress. 相似文献
16.
What drives scientists to start their own company?: An empirical investigation of Max Planck Society scientists 总被引：1，自引：0，他引：1
Studies on academic spin-off companies have shown that the researchers’ scientific potential, experience and established networks with other scientists or companies affect entrepreneurial activity. Most studies investigate official data such as patents and citations or qualitatively study a research group or spin-off formation. Only a few studies focus on the individual scientist. Our study fills this gap by analyzing survey interviews of 2604 scientists working for the Max Planck Society in Germany. Our empirical results indicate that the entrepreneurial activities of scientists heavily depend on patenting activity, entrepreneurial experience, and personal opinions about the benefits of commercializing research and close personal ties to industry. 相似文献
17.
This paper contributes to the debate on the energy efficiency paradox according to which consumers fail to adopt cost-effective, energy efficient technologies over less efficient technologies and therefore fail to reduce energy consumption. Both traditional and behavioural theories are used to investigate the decision-making process of residential consumers with empirical evidence based upon a specially designed quasi-experimental survey of 784 households on the decision to connect to a district-heating system, a more energy efficient alternative to individual heating systems. The results suggest an internal discount rate of around 36 per cent for homeowners, a signal that consumers undervalue future energy costs. We also find the household’s decision to be negatively affected by years of payback up to around 7–8 years. Our findings suggest that neglecting consumer inattention and heuristics can lead to biases which cast doubt on the existence of the energy efficiency paradox. We believe that these results help to explain why some consumers are unlikely to invest in energy efficient technology, particularly those on low incomes. 相似文献
18.
通过对珠江三角洲地区192位高校教师正式调查数据分析发现：高校教师压力来自人际寡助、制度阻力、教研任务、外部期望、课堂组织和职业发展六个方面。教师压力与创造力人格呈负相关关系,但其关系受到教师个人专业技术职务水平的影响。 相似文献
19.
《Research Policy》2019,48(9):103804
In this paper, we explore the impact of a firm's workers’ replacements on innovation performance by using rich matched employer–employee panel data for the Veneto region of Italy. We take the well-known resource-based theory of the firm as our departure point, and develop a set of hypotheses which we test empirically with negative binomial regressions. We find that workers’ replacements significantly dampen innovation performance, coherently with the idea that they generate losses in the tacit knowledge base of the firm. We also find that workers’ replacements are especially detrimental to large and young firms, possibly because large companies benefit comparatively less from ‘diaspora’ effects and because innovative capabilities in young firms are mostly dependent on specific human capital. Finally, our results show that firms’ location in industrial districts significantly mitigates the negative impact of workers’ replacements, and that a similar picture emerges when firms are more exposed to knowledge spillovers, particularly of related knowledge. 相似文献
20.
《Information processing & management》2023,60(3):103328
Stock movement forecasting is usually formalized as a sequence prediction task based on time series data. Recently, more and more deep learning models are used to fit the dynamic stock time series with good nonlinear mapping ability, but not much of them attempt to unveil a market system’s internal dynamics. For instance, the driving force (state) behind the stock rise may be the company’s good profitability or concept marketing, and it is helpful to judge the future trend of the stock. To address this issue, we regard the explored pattern as an organic component of the hidden mechanism. Considering the effective hidden state discovery ability of the Hidden Markov Model (HMM), we aim to integrate it into the training process of the deep learning model. Specifically, we propose a deep learning framework called Hidden Markov Model-Attentive LSTM (HMM-ALSTM) to model stock time series data, which guides the hidden state learning of deep learning methods via the market’s pattern (learned by HMM) that generates time series data. What is more, a large number of experiments on 6 real-world data sets and 13 stock prediction baselines for predicting stock movement and return rate are implemented. Our proposed HMM-ALSTM achieves an average 10% improvement on all data sets compared to the best baseline. 相似文献