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1.
Attenuated performance during intense exercise with limited endogenous carbohydrate (CHO) is well documented. Therefore, this study examined whether caffeine (CAF) mouth rinsing would augment performance during repeated sprint cycling in participants with reduced endogenous CHO. Eight recreationally active males (aged 23?±?2?yr, body mass 84?±?4?kg, stature 178?±?7?cm) participated in this randomized, single-blind, repeated-measures crossover investigation. Following familiarization, participants attended two separate evening glycogen depletion sessions. The following morning, participants completed five, 6?s sprints on a cycle ergometer (separated by 24?s active recovery), with mouth rinsing either (1) a placebo solution or (2) a 2% CAF solution. During a fifth visit, participants completed the sprints without prior glycogen depletion. Repeated-measures ANOVA identified significant main effect of condition (CAF, placebo, and control [P?P?P?P?P?P?相似文献   

2.
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3.
Aims: Exercise combined with adipose tissue lipolytic inhibition augments intramuscular lipid and glycogen use in type 2 diabetes patients. The present study investigates the impact of adipose tissue lipolytic inhibition during exercise on subsequent postprandial glycemic control in type 2 diabetes patients.

Methods: Fourteen male type 2 diabetes patients (age 65?±?2 years, HbA1c 6.7?±?0.1% (50?±?2?mmol/mol)) participated in a double-blind placebo-controlled randomized cross-over study in which subjects performed endurance-type exercise after being administered 250?mg of a nicotinic acid analogue (acipimox; ACP) or a placebo (PLA). A control experiment was included in which no exercise was performed (CON).

Results: Sixty minutes of endurance-type exercise (at 45% Wpeak) did not significantly lower circulating plasma glucose and insulin excursions in PLA when compared with CON (P?=?.300). Acipimox administration strongly reduced circulating plasma FFA concentrations during exercise (P?i.e. postprandial) in ACP when compared with either CON (P?=?.041 and P?=?.002, respectively) or PLA (P?=?.009 and P?=?.001, respectively).

Conclusions: Collectively, exercise with adipose tissue lipolytic inhibition reduces postprandial blood glucose and insulin excursions and, as such, further improves glycemic control in male type 2 diabetes patients.  相似文献   

4.
VO2 fluctuations are argued to be an important mechanism underpinning chronic adaptations following interval training. We compared the effect of exercise modality, continuous vs. intermittent realized at a same intensity, on electrical muscular activity, muscular oxygenation and on whole body oxygen uptake. Twelve participants (24?±?5 years; VO2peak: 43?±?6?mL·?min?1·kg?1) performed (i) an incremental test to exhaustion to determine peak work rate (WRpeak); two randomized isocaloric exercises at 70%WRpeak; (ii) 1 bout of 30 min; (iii) 30 bouts of 1?min work intercepted with 1?min passive recovery. For electromyography, only the CON exercise showed change for the vastus lateralis root-mean-square (+6.4?±?5.1%, P?P?vs. 2.32?±?1.21?mM, respectively, for the CON and INT, P?vs. 356?±?301?sec, respectively, for the CON and INT, P?相似文献   

5.
The effectiveness of a nap as a recovery strategy for endurance exercise is unknown and therefore the present study investigated the effect of napping on endurance exercise performance. Eleven trained male runners completed this randomised crossover study. On two occasions, runners completed treadmill running for 30?min at 75% ?O2max in the morning, returning that evening to run for 20?min at 60% ?O2max, and then to exhaustion at 90% ?O2max. On one trial, runners had an afternoon nap approximately 90?min before the evening exercise (NAP) whilst on the other, runners did not (CON). All runners napped (20?±?10?min), but time to exhaustion (TTE) was not improved in all runners (NAP 596?±?148?s vs. CON 589?±?216?s, P?=?.83). Runners that improved TTE after the nap slept less at night than those that did not improve TTE (night-time sleep 6.4?±?0.7?h vs. 7.5?±?0.4?h, P?r2 ? =??0.76, P?=?.001). In runners that improved TTE, ratings of perceived exertion (RPE) were lower during the TTE on NAP than CON compared to runners that did not improve (?0.4?±?0.6 vs. 0?±?0, P?=?.05). Reduced exercising sense of effort (RPE) may account for the improved TTE after the nap. In conclusion, a short afternoon nap improves endurance performance in runners that obtain less than 7?h night-time sleep.  相似文献   

6.
Load carriage (LC) exercise in physically demanding occupations is typically characterised by periods of low-intensity steady-state exercise and short duration, high-intensity exercise while carrying an external mass in a backpack; this form of exercise is also known as LC exercise. This induces inspiratory muscle fatigue and reduces whole-body performance. Accordingly we investigated the effect of inspiratory muscle training (IMT, 50% maximal inspiratory muscle pressure (PImax) twice daily for six week) upon running time-trial performance with thoracic LC. Nineteen healthy males formed a pressure threshold IMT (n?=?10) or placebo control group (PLA; n?=?9) and performed 60?min LC exercise (6.5?km?h–1) followed by a 2.4?km running time trial (LCTT) either side of a double-blind six week intervention. Prior to the intervention, PImax was reduced relative to baseline, post-LC and post-LCTT in both groups (pooled data: 13?±?7% and 16?±?8%, respectively, p?PImax increased +31% (p?TT (+18%, p?PImax at each time point was unchanged (13?±?11% and 17?±?9%, respectively, p?>?.05). In IMT only, heart rate and perceptual responses were reduced post-LC (p?p?相似文献   

7.
This study compared heart rate recovery (HRR) after incremental maximal exercise performed at the same external power output (Pext) on dry land ergocycle (DE) vs. immersible ergocycle (IE). Fifteen young healthy participants (30?±?7 years, 13 men and 2 women) performed incremental maximal exercise tests on DE and on IE. The initial Pext on DE was 25?W and was increased by 25?W/min at a pedalling cadence between 60 and 80?rpm, while during IE immersion at chest level in thermoneutral water (30°C), the initial Pext deployment was at a cadence of 40?rpm which was increased by 10?rpm until 70?rpm and thereafter by 5?rpm until exhaustion. Gas exchange and heart rate (HR) were measured continuously during exercise and recovery for 5?min. Maximal HR (DE: 176?±?15 vs. IE 169?±?12?bpm) reached by the subjects in the two conditions did not differ (P?>?.05). Parasympathetic reactivation parameters (ΔHR from 10 to 300?s) were compared during the DE and IE HR recovery recordings. During the IE recovery, parasympathetic reactivation in the early phase was more predominant (HRR at Δ10–Δ60?s, P?<?.05), but similar in the late phase (HRR at Δ120–Δ300?s, P?>?.05) when compared to the DE condition. In conclusion, incremental maximal IE exercise at chest level immersion in thermoneutral water accelerates the early phase parasympathetic reactivation compared to DE in healthy young participants.  相似文献   

8.
Physical inactivity is a major contributor to low-grade systemic inflammation. Most of the studies characterizing interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) release from exercising legs have been done in young, healthy men, but studies on inactivity in older people are lacking. The impact of 14 days of one-leg immobilization (IM) on IL-6 and TNF-α release during exercise in comparison to the contralateral control (CON) leg was investigated. Fifteen healthy men (age 68.1?±?1.1?year (mean?±?SEM); BMI 27.0?±?0.4 kg·m2; VO2max 33.3?±?1.6 ml·kg?1·min?1) performed 45?min of two-leg dynamic knee extensor exercise at 19.5?±?0.9 W. Arterial and femoral venous blood samples from the CON and the IM legs were collected every 15?min during exercise, and thigh blood flow was measured with ultrasound Doppler. Arterial plasma IL-6 concentration increased with exercise (rest vs. 45?min, main effect p?p?p?=?.085, effect size 0.28) higher in the IM leg compared to the CON leg (288 (95% CI: 213–373) vs. 220 (95% CI: 152–299) pg·min?1, respectively). There was no release of TNF-α in either leg and arterial concentrations remained unchanged during exercise (p?>?.05). In conclusion, exercise induces more pronounced IL-6 secretion in healthy older men. Two weeks of unilateral immobilization on the other hand had only a minor influence on IL-6 release. Neither immobilization nor exercise had an effect on TNF-α release across the working legs in older men.  相似文献   

9.
We tested the hypothesis that backward downhill walking (eccentric component) impairs both voluntary activation and muscle contractile properties in the plantar flexors and delays recovery as compared to a gradient and distance-matched uphill walk. Fourteen males performed two 30-min walking exercises (velocity: 1?m/?s; grade: 25%; load: 12% of body weight), one downhill (DW) and one uphill (UP), in a counterbalanced order, separated by 6?weeks. Neuromuscular test sessions were performed before, after, 24-, 48- and 72-h post-exercise, including motor nerve stimulations during brief (5?s) and sustained (1?min) maximal isometric voluntary contractions of the plantar flexors. DW (?18.1?±?11.1%, P?P?=.15), decreased torque production during brief contractions for at least three days post-exercise (P?P?P?=?.024) and DW (?25.6?±?10.3%, P?P?=?.001) was lower in DW than UP. Peak twitch torque and maximum rates of torque development and relaxation were equally reduced after UP and DW (P?P?P?>?.05). Using a direct comparison, the capacity to drive the plantar flexors during sustained contractions remains sub-optimal during the three-day recovery period in response to non-exhaustive, downhill backward walking in reference to an uphill exercise matched for distance covered.  相似文献   

10.
Many physically active individuals have undertaken intermittent fasting to reduce their daily caloric intake. However, abstaining from meals for a specific length of time may lead to the acute disturbance of highly carbohydrate-dependent exercise performance. The purpose of this study was to observe the effect of 10 days of intermittent fasting on high-intensity type exercises, Wingate anaerobic (WT) and prolonged high-intensity time-to-exhaustion (HIT) cycling test. Twenty participants were randomised into an intermittent fasting (FAS) and a control group (CON). One day after baseline data collection on Day-0 where participants consumed their recommended daily caloric intake (FAS?=?2500?±?143?kcal?day?1; CON?=?2492?±?20?kcal?day?1) served over a course of five meals, the FAS group consumed only four meals where 40% was restricted by the omission of lunch (FAS?=?1500?±?55?kcal?day?1). This diet was then continued for 10 days. Data on exercise performance and other dependent variables were collected on Day-2, -4, -6, -8 and -10. A reduction in WT power in the FAS group was observed on Day-2 (821.74?±?66.07?W) compared to Day-0 (847.63?±?95.94?W) with a moderate effect size (p?p?p?相似文献   

11.
The objective of this study was to identify the effects of mouth rinsing with a 6% and 16% carbohydrate solution (CHO) on time trial performance when compared to a 0% control (PLA) when in a fed state. Twelve recreationally active males underwent three trials by which they had to complete a set workload (600?±?65?W) in a fed state. Throughout each trial, participants rinsed their mouths with a 25?ml bolus of a 0% PLA, 6% or 16% CHO (maltodextrin) for every 12.5% of work completed. Rating of perceived exertion (RPE) and heart rate were recorded every 12.5% of total work. Performance times and power output improved significantly when using the 6% and 16% CHO versus the PLA trial (6% versus PLA, p?=?.002 and 16% versus PLA, p?=?.001). When comparing the performance times of the 6% to 16% CHO, no significance was observed (p?=?.244). There was no significant difference between heart rate levels or RPE values across the three trials. In conclusion, mouth rinsing with a 6% or 16% CHO solution has a positive effect on a cycling time trial performance undertaken in a fed state.  相似文献   

12.
The purpose of our study was to examine the physiological, perceptual, and performance effects of wearing a phase change cooling garment (CG) during an interval exercise routine in the heat. Sixteen male participants (age 23?±?3 years, ht 1.76?±?0.11?m; wt 78.5?±?11.2?kg; body fat 15.2?±?5.8%) completed two trials (one with phase change inserts, CG, and one control without inserts) consisting of two submaximal exercise portions separated by 5-minute seated rest, and a final maximal effort performance bout. Each submaximal bout involved 30?seconds or 1?minute of muscular endurance and agility exercises and 5?minutes of treadmill jogging and step-ups. The performance bout included 30?seconds or 1?minute of muscular endurance and agility exercises, with participants completing as many repetitions as possible, followed by a 15-minute recovery (active and passive). Rectal temperature (Tre) and heart rate were not different between trials, however change in Tre from baseline was improved during 10 and 15 minutes of recovery with the CG (P?<?.05). Mean skin temperature was lower using the CG vs control throughout the trial (P?<?.05). Thermal sensation was lower when using the CG compared to control (P?<?.001). There were no differences in any outcomes of the performance exercises (P?>?.05). These findings indicate that the continuous use of a CG during an interval style workout in the heat provides improvements in thermal sensation, however, only minimal thermophysiological benefits, and no performance augmentation.  相似文献   

13.
This study investigated the impact that mouth rinsing carbohydrate solution has on skill-specific performance and reaction time following a fatigue-inducing bout of fencing in epee fencers. Nine healthy, national-level epee fencers visited a laboratory on two occasions, separated by a minimum of five days, to complete a 1-minute lunge test and Stroop test pre- and post-fatigue. Heart rate and ratings of perceived exertion (RPE) were recorded during completion of the fatiguing protocol. Between fights the participant’s mouth rinsed for 10?seconds, either 25?ml of 6.7% maltodextrin solution (MALT) or water (PLAC). Blood lactate and glucose were recorded at baseline, pre- and post-testing. Results showed an increase in heart rate and overall RPE over time in both conditions. There were no differences in blood glucose (F(1,8)?=?.63, P?=?.4, ηp?=?.07) or blood lactate levels (F(1,8)?=?.12, P?=?.70, ηp?=?.01) between conditions as a function of time. There was a significant improvement in lunge test accuracy during the MALT trial (F(1,8)?=?5.21, P?=?.05, ηp?=?.40) with an increase from pre (81.2?±?8.3%) to post (87.6?±?9.4%), whereas there was no significant change during the placebo (pre 82.1?±?8.8%, post 78.8?±?6.4%). There were no recorded differences between conditions in response time to congruent (F(1,8)?=?.33, P?=?.58, ηp?=?.04) or incongruent stimuli (F(1,8)?=?.19, P?=?.68, ηp?=?.02). The study indicates that when fatigued mouth rinsing MALT significantly improves accuracy of skill-specific fencing performance but no corresponding influence on reaction time was observed.  相似文献   

14.
Parkour is a modern physical activity that consists of using the environment, mostly urban, as a playground of obstacles. The aims of this study were (i) to investigate age, anthropometric and training characteristics of Parkour practitioners, called ‘traceurs’ and (ii) to assess jump performances and muscular characteristics of traceurs, compared to those of gymnasts and power athletes. The mean age of the population of traceurs studied (n?=?130) was 19.4?±?4.3 years, women represented 12.4% of the total field and mean training volume was 8.1?±?0.5?hours/week. Vertical and long jump performances were analysed on smaller samples of participants (four groups, n?=?15 per group); and eccentric (?90°?s?1, ?30°?s?1), concentric (30°?s?1, 90°?s?1) and isometric knee extensors torques were evaluated by means of an isokinetic dynamometer. Traceurs showed greater (P?P?P?P?相似文献   

15.
This study aimed to describe the body composition and physiological changes which take place during the in-season and recovery periods of a group of natural bodybuilders. Natural male bodybuilders (n?=?9) were assessed 16 (PRE16), 8 (PRE8), and 1 (PRE1) week(s) before, and 4 (POST4) weeks after a bodybuilding competition. Assessments included body composition, resting metabolic rate (RMR), serum hormones, and 7-day weighed food and training diaries. Change in parameters was assessed using repeated-measures analysis of variance. Dietary protein intake remained high throughout the study period (2.8–3.1?g?kg?1?d?1). Fat mass (FM) was significantly reduced from PRE16 to PRE1 (8.8?±?3.1 vs. 5.3?±?2.4?kg, P?.01). There was a small decrease in lean mass (LM) from PRE8 to PRE1 (71.8?±?9.1 vs. 70.9?±?9.1?kg, P?P?>?.05). Large reductions in total and free testosterone (16.4?±?4.4 vs. 10.1?±?3.6?nmol?L?1, P?. 116.8?±?76.9?pmol?L?1, P?. 19.9?±?7.6?nmol?L?1, P?. 72.5?±?8.5?kg, P?. 25.4?±?9.3?nmol?L?1, P?相似文献   

16.
Abstract

This study investigated the effects of acute caffeine ingestion following short-term creatine supplementation on an incremental cycling to exhaustion task. Twelve active males performed the task under three conditions: baseline condition (BASE, no ergogenic aid), creatine plus caffeine condition (CRE + CAF), and creatine with placebo condition (CRE + PLA). Following the establishment of BASE condition, participants were administered CRE + CAF (0.3 g·kg?1·day?1 of creatine for 5 days followed by 6 mg·kg?1 of caffeine 1 h prior to testing) and CRE + PLA (0.3 g·kg?1·day?1 of creatine for 5 days followed by 6 mg·kg?1 of placebo 1 h prior to testing) in a double-blind, randomized crossover and counterbalancing protocol. No significant differences were observed in relative maximal oxygen consumption ([Vdot]O2max) (51.7±5.5, 52.8±4.9 and 51.3±5.6 ml·kg?1·min?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05) and absolute [Vdot]O2max (3.6±0.4, 3.7±0.4 and 3.5±0.5 l·min?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05). Blood samples indicated significantly higher blood lactate and glucose concentrations in the CRE + CAF among those in the BASE or CRE + PLA condition during the test (P<0.05). The time to exhaustion on a cycling ergometer was significantly longer for CRE + CAF (1087.2±123.9 s) compared with BASE (1009.2±86.0 s) or CRE + PLA (1040.3±96.1 s). This study indicated that a single dose of caffeine following short-term creatine supplementation did not hinder the creatine–caffeine interaction. In fact, it lengthened the time to exhaustion during an incremental maximum exercise test. However, this regime might lead to the accumulation of lactate in the blood.  相似文献   

17.
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18.
This study (1) compared the physiological responses and performance during a high-intensity interval training (HIIT) session incorporating externally regulated (ER) and self-selected (SS) recovery periods and (2) examined the psychophysiological cues underpinning SS recovery durations. Following an incremental maximal exercise test to determine maximal aerobic speed (MAS), 14 recreationally active males completed 2 HIIT sessions on a non-motorised treadmill. Participants performed 12?×?30?s running intervals at a target intensity of 105% MAS interspersed with 30?s (ER) or SS recovery periods. During SS, participants were instructed to provide themselves with sufficient recovery to complete all 12 efforts at the required intensity. A semi-structured interview was undertaken following the completion of SS. Mean recovery duration was longer during SS (51?±?15?s) compared to ER (30?±?0?s; p?d?=?1.46?±?0.46). Between-interval heart rate recovery was higher (SS: 19?±?9?b?min?1; ER: 8?±?5?b?min?1; p?d?=?1.43?±?0.43) and absolute time ≥90% maximal heart rate (HRmax) was lower (SS: 335?±?193?s; ER: 433?±?147?s; p?=?.075; d?=?0.52?±?0.39) during SS compared to ER. Relative time ≥105% MAS was greater during SS (90?±?6%) compared to ER (74?±?20%; p?d?=?0.87?±?0.40). Different sources of afferent information underpinned decision-making during SS. The extended durations of recovery during SS resulted in a reduced time ≥90% HRmax but enhanced time ≥105% MAS, compared with ER exercise. Differences in the afferent cue utilisation of participants likely explain the large levels of inter-individual variability observed.  相似文献   

19.
Purpose: The purpose of this study was to investigate whether loads carried in a backpack, with a load mass ranging from 0 to 20?kg, causes respiratory muscle fatigue. Methods: Eight males performed four randomised load carriage (LC) trials comprising 60?min walking at 6.5?km?h?1 wearing a backpack of either 0 (LC0), 10 (LC10), 15 (LC15) or 20?kg (LC20). Inspiratory (PImax) and expiratory (PEmax) mouth pressures were assessed prior to and immediately following each trial. Pulmonary gas exchange, heart rate (HR), blood lactate and glucose concentration and perceptual responses were recorded during the first and final 60?s of each trial. Results: Group mean PImax and PEmax were unchanged following 60-min load carriage in all conditions (p?>?.05). There was an increase over time in pulmonary gas exchange, HR and perceptions of effort relative to baseline measures during each trial (p?p?>?.05). Conclusions: These findings indicate that sub-maximal walking with no load or carrying 10, 15 or 20?kg in a backpack for up to 60?min does not cause respiratory muscle fatigue despite causing an increase in physiological, metabolic and perceptual parameters.  相似文献   

20.
Background: High-intensity interval training (HIIT) has been shown to improve cardiometabolic health during supervised lab-based studies but adherence, enjoyment, and health benefits of HIIT performed independently are yet to be understood. We compared adherence, enjoyment, and cardiometabolic outcomes after 8 weeks of HIIT or moderate-intensity continuous training (MICT), matched for energy expenditure, in overweight and obese young adults. Methods: 17 adults were randomized to HIIT or MICT. After completing 12 sessions of supervised training over 3 weeks, participants were asked to independently perform HIIT or MICT for 30 min, 4 times/week for 5 weeks. Cardiometabolic outcomes included cardiorespiratory fitness (VO2 peak), lipids, and inflammatory markers. Exercise enjoyment was measured by the validated Physical Activity Enjoyment Scale. Results: Exercise adherence (93.4?±?3.1% vs. 93.1?±?3.7%, respectively) and mean enjoyment across the intervention (100.1?±?4.3 vs. 100.3?±?4.4, respectively) were high, with no differences between HIIT and MICT (p?>?.05). Similarly, enjoyment levels did not change over time in either group (p?>?.05). After training, HIIT exhibited a greater decrease in low-density lipoprotein cholesterol than MICT (?0.66?mmol?L?1 vs. ?0.03?mmol?L?1, respectively) and a greater increase in VO2 peak than MICT (p?<?.05, +2.6?mL?kg?min?1 vs. +0.4?mL?kg?min?1, respectively). Interleukin-6 and C-reactive protein increased in HIIT (+0.5?pg?mL?1 and +?31.4?nmol?L?1, respectively) and decreased in MICT (?0.6?pg?mL?1 and ?6.7?nmol?L?1, respectively, p?<?.05). Conclusions: Our novel findings suggest that HIIT is enjoyable and has high unsupervised adherence rates in overweight and obese adults. However, HIIT may be associated with an increase in inflammation with short-term exercise in this population.  相似文献   

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