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1.
The aims of this study were to determine the distribution of the AMPD1 genotype among groups of high-level Polish power-oriented athletes, and to investigate potential associations between genetic polymorphism in exon 2 of the AMPD1 gene and power-oriented athlete status. Altogether, 158 male Polish power-oriented athletes were genotyped by PCR-RFLP. The genetic control group comprised 160 unrelated male volunteers. We observed significant differences in genotype distribution when all 158 athletes (89.25% CC, 10.75% CT, 0.00% TT; P = 0.0025) were compared with controls (75.00% CC, 23.75% CT, 1.25% TT). A significant deficiency of the T allele was noted in all subgroups (short-distance runners: 5.21%, P = 0.032; short-distance swimmers: 5.56%, P = 0.031; weightlifters: 5.36%, P = 0.024) compared with controls (13.13%), while this trend was even stronger when the frequency of the T allele was compared between controls and all 158 athletes (5.38%, P = 0.0007). Our results indicate a lower frequency of the AMPD1 exon 2 T34 allele in elite Polish power-oriented athletes. Our data suggest that the C allele may help athletes to attain elite status in power-oriented sports.  相似文献   

2.
Abstract

Environmental and genetic factors influence muscle function, resulting in large variations in phenotype between individuals. Multiple genetic variants (polygenic in nature) are thought to influence exercise-related phenotypes, yet how the relevant polymorphisms combine to influence muscular strength in individuals and populations is unclear. In this analysis, 22 genetic polymorphisms were identified in the literature that have been associated with muscular strength and power phenotypes. Using typical genotype frequencies, the probability of any given individual possessing an “optimal” polygenic profile was calculated as 0.0003% for the world population. Future identification of additional polymorphisms associated with muscular strength phenotypes would most likely reduce that probability even further. To examine the genetic potential for muscular strength within a human population, a “total genotype score” was generated for each individual within a hypothetical population of one million. The population expressed high similarity in polygenic profile with no individual differing by more than seven genotypes from a typical profile. Therefore, skeletal muscle strength potential within humans appears to be limited by polygenic profile similarity. Future research should aim to replicate more genotype–phenotype associations for muscular strength, because only five common genetic polymorphisms identified to date have positive replicated findings.  相似文献   

3.
The objective of this study was to test the association of the rs1049305 (G > C) variant within the 3?-untranslated region of the aquaporin 1 gene, AQP1, with changes in body weight, post-race serum sodium concentration and performance in Ironman triathletes. Five hundred and four male Ironman triathletes were genotyped for the rs1049305 variant within the AQP1 gene. Change in pre- and post-race body weight was calculated for 470 triathletes and used as a proxy for changes in body fluid during the race, as well as to divide triathletes into biologically relevant weight-loss groups (0–3%, 3–5% and >5%). There were no rs1049305 genotype effects on post-race serum sodium concentrations (P = 0.647), pre-race weight (P = 0.610) nor relative weight change during the Ironman Triathlons (P = 0.705). In addition, there were no significant differences in genotype (P = 0.640) nor allele (P = 0.643) distributions between the weight loss groups. However, triathletes who carry a C-allele were found to complete the 42.2-km run stage faster (mean 286, s = 49 min) than triathletes with a GG genotype (mean 296, s = 47 min; P = 0.032). The AQP1 rs1049305 variant is associated with running performance, but not relative body weight change, during the 2000, 2001 and 2006 South African Ironman Triathlons.  相似文献   

4.
Abstract

The adenosine monophosphate deaminase (AMPD1) gene seems to be an important regulator of skeletal muscle energy metabolism during exercise. A nonsense C34T mutation in the AMPD1 gene results in a premature stop codon, thus stopping protein synthesis. The aim of this study was to determine the AMPD1 C34T mutation frequency distribution among 155 Israeli athletes (endurance athletes, n=74; sprinters, n=81) and 142 healthy controls. Genotyping of the AMPD1 C34T (rs5810761) mutation was performed using polymerase chain reaction (PCR). Results showed that the genotype subtype did not differ by gender in the athletes (P=0.18) or the controls (P=0.79). The AMPD1 C34T genotype distribution was in line with Hardy-Weinberg equilibrium within all groups (P>0.05). The genotype distribution and allele frequencies were similar in the groups of endurance athletes, sprinters, and controls (P=0.455). Similarly, no significant differences were observed between the subgroups of elite endurance athletes and national endurance athletes (P=0.78), or between elite and national sprinters (P=0.46). In conclusion, the AMPD1 C34T mutation is not associated with endurance athletes’ status, at least in the present group of Israeli athletes. This suggests that elite athletic status can be achieved despite a partial deficiency in AMPD1, as marked by the AMPD1 CT genotype.  相似文献   

5.
Environmental and genetic factors influence muscle function, resulting in large variations in phenotype between individuals. Multiple genetic variants (polygenic in nature) are thought to influence exercise-related phenotypes, yet how the relevant polymorphisms combine to influence muscular strength in individuals and populations is unclear. In this analysis, 22 genetic polymorphisms were identified in the literature that have been associated with muscular strength and power phenotypes. Using typical genotype frequencies, the probability of any given individual possessing an "optimal" polygenic profile was calculated as 0.0003% for the world population. Future identification of additional polymorphisms associated with muscular strength phenotypes would most likely reduce that probability even further. To examine the genetic potential for muscular strength within a human population, a "total genotype score" was generated for each individual within a hypothetical population of one million. The population expressed high similarity in polygenic profile with no individual differing by more than seven genotypes from a typical profile. Therefore, skeletal muscle strength potential within humans appears to be limited by polygenic profile similarity. Future research should aim to replicate more genotype-phenotype associations for muscular strength, because only five common genetic polymorphisms identified to date have positive replicated findings.  相似文献   

6.
ABSTRACT

The aim was to investigate how measurements of the lipidome differ according to the level and intensity of physical activity in a population at high risk of type 2 diabetes (T2DM). A targeted metabolomics platform provided quantitative molecular data on lipid species. Linear regression examined the associations between plasma lipid concentrations, particle size and time spent in objectively measured physical activity intensity domains, in increments of 500 counts per minute (cpm) (up to >4500 cpm (~>5.6METs)). Results are presented as % difference in the concentration (lower/higher) or particle size (smaller/larger) per 10 min of activity within each intensity. Five hundred and nine participants were included. Time spent in the lowest physical activity intensity domain (<500 cpm) was unfavourably associated with VLDL (2%), HDL (?2%) and Apolipoprotein A-1 particle concentrations (?2%) and HDL diameter (?2%). Conversely, time spent in intensities ≥1000 cpm were favourably associated with HDL subclass concentrations; with stronger associations seen at moderate intensities (2000-3999 cpm (~4.5METs)). For Apolipoprotein-B concentration and VLDL particle concentration and size, a negative association was consistently observed at the highest physical activity intensity only. If these associations are causal, HDL subclasses appear sensitive to light-intensities whereas only the high category of physical activity intensity was consistently associated with VLDL subclasses.  相似文献   

7.
Several genetic loci have been associated with risk of Achilles tendon pathology (ATP) within South African and Australian populations. The aim of this study was, therefore, to evaluate eight previously implicated genetic variants in an independent British population. A total of 130 asymptomatic controls (CON) and 112 participants clinically diagnosed with ATP comprising 87 individuals with chronic Achilles tendinopathy (TEN) and 25 with Achilles tendon ruptures (RUP) were included. All participants were genotyped for variants within the COL5A1, MIR608, IL-1β, IL-6 and CASP8 genes. Primary findings implicated COL5A1 and CASP8. Three inferred allele combinations constructed from COL5A1 rs12722, rs3196378 and rs71746744 were identified as risk modifiers. The T–C–D combination was associated with increased risk of ATP (P = 0.023) and RUP (P < 0.001), the C–A–I combination was associated with increased risk of ATP (P = 0.011), TEN (P = 0.011) and RUP (P = 0.011) and the C–C–D combination was associated with decreased risk of ATP (P = 0.011) and RUP (P = 0.004). The CASP8 rs3834129 DD genotype was associated with decreased risk of TEN (P = 0.020, odds ratio: 0.45, 95% confidence interval: 0.22–0.90) and the CASP8 I–G (rs3834129–rs1045485) inferred allele combination was associated with increased risk of TEN (P = 0.031). This study further highlights the importance of polymorphisms within COL5A1 and CASP8 in the aetiology of ATP.  相似文献   

8.
对广州市近郊农业人口体质进行了测试与评价，发现近郊农业人口的体质总体优于远郊农业人口，这种差异现象在男子组尤为明显。近郊农业人口与远郊农业人口的体质在壮年后期逐步出现分化，远郊农业人口的各项体质指标下降的速度比近郊农业人口快。  相似文献   

9.
The purposes of this study were to describe and compare the specific physical activity choices and sedentary pursuits of African American and Caucasian American girls. Participants were 1,124 African American and 1,068 Caucasian American eighth-grade students from 31 middle schools. The 3-Day Physical Activity Recall (3DPAR) was used to measure participation in physical activities and sedentary pursuits. The most frequently reported physical activities were walking, basketball, jogging or running, bicycling, and social dancing. Differences between groups were found in 11 physical activities and 3 sedentary pursuits. Participation rates were higher in African American girls (p < or = .001) for social dancing, basketball, watching television, and church attendance but lower in calisthenics, ballet and other dance, jogging or running, rollerblading, soccer, softball or baseball, using an exercise machine, swimming, and homework. Cultural differences of groups should be considered when planning interventions to promote physical activity.  相似文献   

10.
Time-to-exhaustion (TTE) trials are used in a laboratory setting to measure endurance performance. However, there is some concern with their ecological validity compared with time-trials (TT). Consequently, we aimed to compare cycling performance in TTE and TT where the duration of the trials was matched. Seventeen trained male cyclists completed three TTE trials at 80, 100 and 105% of maximal aerobic power (MAP). On a subsequent visit they performed three TT over the same duration as the TTE. Participants were blinded to elapsed time, power output, cadence and heart rate (HR). Average TTE was 865 ± 345 s, 165 ± 98 s and 117 ± 45 s for the 80, 100 and 105% trials respectively. Average power output was higher for TTE (294 ± 44 W) compared to TT (282 ± 43 W) at 80% MAP (P < 0.01), but not at 100 and 105% MAP (P > 0.05). There was no difference in cadence, HR, or RPE for any trial (P > 0.05). Critical power (CP) was also higher when derived from TTE compared to TT (P < 0.01). It is concluded that TTE results in a higher average power output compared to TT at 80% MAP. When determining CP, TTE rather than TT protocols appear superior.  相似文献   

11.
A 30-s 'all-out' power protocol was studied in four groups of racing cyclists including internationals (n = 8), Category 1 (n = 10), Category 2 (n = 15) and Category 3 (n = 11). Following warm-up each subject completed five trials interspersed by 3 min of low intensity exercise on an ergowheel racing cycle ergometry system at a power output of 15 W kg-1 body weight, generated at 130 rev min-1. Temporal indices of performance included delay time (DT) to achieve the power criterion, total time (TT) of the maintenance of the power criterion and the ratio of TT/DT. 'Explosive' leg strength was assessed from a vertical jump. The results indicated that international and Category 1 cyclists had lower DT (2.2 +/- 0.1 s and 2.1 +/- 0.0 s, respectively; P less than 0.05), higher TT (28.1 +/- 0.7 s and 27.0 +/- 0.7 s, respectively; P less than 0.05) and elevated TT/DT (12.8 and 12.9, respectively; P less than 0.01). 'Explosive' leg strength was also higher (P less than 0.05) in the internationals than in the other groups of cyclists. The protocol provides a sport-related method for the assessment of short term endurance performance ability in racing cyclists which may be of value in identifying the anaerobic capability of individual cyclists.  相似文献   

12.
目的：研究黑龙江汉族速滑运动员优秀耐力能力与肌型肌酸激酶基因（CKMM）A/G多态的关联性。方法：应用PCR-RFLP法测定120名黑龙江籍汉族健康大学生及25名黑龙江汉族耐力型速滑运动员CKMM基因A/G位点的基因型和等位基因的频率分布。结果：大学生等位基因频率为A=87%,G=13%,基因型频率为A/A=76%,A/G=22%,G/G=2%;速滑运动员等位基因频率为A=84%,G=16%,基因型频率为A/A=68%,A/G=32%,经卡方检验符合Hardy-Weinberg遗传平衡定律,两组的基因型频率和等位基因频率在男女间无显著性差异,与欧美人群相比有显著性差异,与我国北方汉族人及韩国人相比差异不具有显著性。两组间基因型频率和等位基因频率无显著性差异。结论：黑龙江汉族耐力型速滑运动员的优秀耐力素质与CKMM基因N coⅠ多态性无关,该位点不能作为其耐力素质选材的遗传学标记。  相似文献   

13.
Abstract

High-level physical performance in rhythmic gymnastics is influenced by numerous skills and anthropometric factors. In order to understand if genetic predisposition could play a role to define the elite rhythmic gymnast phenotype, we analysed the frequency of common polymorphisms linked to genes correlated with body mass (ADRB2 and FTO), explosive strength (ACTN3 and ACE), and joint mobility (COL5A1), in 42 gymnasts involved in National and International events, and in 42 control girls. Our results demonstrated that high-level rhythmic gymnasts constituted a genetically selected population showing higher frequency of: (a) ADRB2 and FTO alleles linked to low body mass index and low fat mass; (b) COL5A1 CT genotype linked to high joint mobility and to the occurrence of genu recurvatum, but also to a higher incidence of injuries. ACTN3 and ACE polymorphisms did not appear to be connected with the phenotype of high-level rhythmic gymnast. Based on these data, it can be assumed that these polymorphisms could positively affect the phenotype and performance of gymnasts.  相似文献   

14.
This study investigated the effects on neuromuscular performance of a 6-week Optimal Load Training (OLT) and a novel modified Complex Training (MCT) (complex pairs: the same exercise using a moderate and an OL) in basketball players, in-season. Eighteen male athletes were randomly assigned to one of the protocols. Anthropometric measurements were taken to evaluate body composition. Lower- and upper-body maximum dynamic strength, countermovement jump (CMJ), standing long jump (SLJ), 10-m sprint and change of direction (COD) were also assessed. Moderate-to-large strength gains (presented as percentage change ± 90% confidence limits) were obtained for half-squat (OLT: 10.8 ± 5.3%; MCT: 17.2 ± 11.6%) and hip thrust (OLT: 23.5 ± 17.7%; MCT: 28.2 ± 19.0%). OLT athletes achieved likely small improvements in sprint (1.6 ± 1.6%) and COD (3.0 ± 3.2%). Players in the MCT attained likely moderate improvements in COD (3.0 ± 2.0%) and possibly small in SLJ (2.5 ± 4.6%). No protocol relevantly affected CMJ or body composition. An ANCOVA test revealed unclear between-group differences. In conclusion, both protocols increased basketball players’ strength without the use of heavy loads (> 85% 1RM) and without impairing sprint, CMJ and SLJ performance. These findings suggest that basketball strength and conditioning professionals may use either method to counteract strength losses during the season.  相似文献   

15.
This essay explores the growth of boxing among the African populations on the Witwatersrand region of South Africa between 1924 and 1959. It details how the sport's jump in popularity with Africans paralleled migration to Johannesburg. Africans increasingly saw boxing as an activity and skill conducive with survival in this new environment, and thus the sport grew in popularity, stature, and skill-level amongst this emergent urban population. The essay further explores the various ways that the sport was disseminated and popularized during the era, thus detailing how the sport reached both the African masses and petit-bourgeois educated elite. As their presence in Johannesburg became more and more permanent, boxing came to encompass various meanings and ideals, such as notions of discipline, independence and civility, to these urban populations.  相似文献   

16.
就2010年第19届世界杯足球决赛阶段64场比赛的145个失球,对当今世界各大洲最高水平足球队在比赛防守中所暴露出各种现象进行分析和研究。结果表明：四大洲球队其失球的主要因素均以盯人不紧所占比例居首位;欧洲和美洲球队在比赛中的防守能力总体要好于亚洲和非洲球队;前四名球队因身体素质和技战术水平的差异,在失球的防守中各有不同特征表现。  相似文献   

17.
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18.
ABSTRACT

Perceptions of physical self-concept are critical to physical activity participation. In line with the reciprocal effects model of causal ordering (REM), higher perceptions of physical self-concept can function as a facilitator to physical activity, and can arise as a result of engaging in physical activity. While this relationship has been predominantly tested in physical activity contexts, directional tests between physical self-concept and sport specific outcomes are limited. The current study aimed to evaluate the generalizability of the REM to sport commitment and physical self-concept in youth athletes. Over 24 months, adolescent females (N = 215) completed self-report questionnaires at Time 1 (T1) and two years later (Time 2; T2). Using structural equation modeling, the reciprocal effects model demonstrated that the path leading from T1 physical self-concept to T2 sport commitment was significant (p = .02), whereas the path leading from T1 sport commitment to T2 physical self-concept was not significant (p = .23). The results suggest a unidirectional relationship and may underscore the importance of focusing on the physical self-concept in the development of strategies geared towards improving adolescent female’s sport participation.  相似文献   

19.
A 30‐s ‘all‐out’ power protocol was studied in four groups of racing cyclists including internationals (n = 8), Category 1 (n = 10), Category 2 (n = 15) and Category 3 (n = 11). Following warm‐up each subject completed five trials interspersed by 3 min of low intensity exercise on an ergowheel racing cycle ergometry system at a power output of 15 W kg–1 body weight, generated at 130 rev min–1. Temporal indices of performance included delay time (DT) to achieve the power criterion, total time (TT) of the maintenance of the power criterion and the ratio of TT/DT. ‘Explosive’ leg strength was assessed from a vertical jump. The results indicated that international and Category 1 cyclists had lower DT (2.2 ± 0.1s and 2.1 +0.0s, respectively; P<0.05), higher TT (28.1 ±0.7s and 27.0+0.7s, respectively; P<0.05) and elevated TT/DT (12.8 and 12.9, respectively; P<0.01). ‘Explosive’ leg strength was also higher (P<0.05) in the internationals than in the other groups of cyclists. The protocol provides a sport‐related method for the assessment of short term endurance performance ability in racing cyclists which may be of value in identifying the anaerobic capability of individual cyclists.  相似文献   

20.
Abstract

Quiet eye training (QET) may be a more effective method for teaching children to catch than traditional training (TT) methods, but it is unclear if the benefits accrued persist in the long term. Thirty children were randomly allocated into a QET or TT group and, while wearing a mobile eye tracker, underwent baseline testing, training and two retention tests over a period of eight weeks, using a validated throw and catch task. During training, movement-related information was provided to both groups, while the QET group received additional instruction to increase the duration of their targeting fixation (QE1) on the wall prior to the throw, and pursuit tracking (QE2) period on the ball prior to catching. In both immediate (R1) and delayed (R2, six weeks later) retention tests, the QET group had a significantly longer QE1 duration and an earlier and longer QE2 duration, compared to the TT group, who revealed no improvements. A performance advantage was also found for the QET compared to the TT group at both R1 and R2, revealing the relatively robust nature of the visuomotor alterations. Regression analyses suggested that only the duration of QE1 predicted variance in catch success post-training, pointing to the importance of a pre-programming visuomotor strategy for successful throw and catch performance.  相似文献   

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