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1.
1 Introduction AmatrixA∈Cn×missaidtobecentrohermitianifA =Jn AJm,andskewcentrohermitianifA =-Jn AJm,where Adenotetheconjugateofthema trixAandJlisthepermutationmatrixoforderlwithonesonthecrossdiagonal(bottomlefttotopright)andzeroselsewhere .ThehermitianToeplitzmatricesformanimportantsubclassofcentrohermi tianmatriceswhichoccurnaturallyindigitalsignalprocessingandotherareas ,seeforinstance[1] andreferencetherein .Thecentrohermitianandrelatedmatricesrecentlyplayanimportantroleinthesolu…  相似文献   

2.
As an easy application of the intermediate value theorem, one can show that for any continuous function f: [0, 1] → ? with f (0) = f (1), there are points a, a + 1/2 both in [0, 1] such that f (a) = f (a + 1/2). In this note, we show that this property holds with 1/2 replaced by any number of the form 1/n for a positive integer n. More interestingly, we show that this is false for every number not of the form 1/n.  相似文献   

3.
This empirically driven paper is about workplace learning with specific focus on the ‘work’ of consuming practices. By consuming we refer to the eating, and the drinking, and (at times) to the smoking that workers, in most organisations, do on a daily basis. Indeed, it is the quotidian nature of consuming, coupled with its absence from workplace learning research that make them noteworthy practices to explore. In using the term practice we draw on the recent tranche of practice based theorisations: notably Schatzki (1996, Organization Studies, 26(3), 465-484, 2005, Organization Studies, 27(12), 1863-1873, 2006) and Gherardi (Human Relations, 54(1), 131-139, 2001, 2006, Learning Organization, 16(5), 352-359, 2009). The paper frames consuming practices as ‘dispersed’ (general) practices and, illustrated through empirical data from multiple projects, we progressively outline how these contribute to the learning of ‘integrative’ (specialized work) practices. Our overall aim is to (re)position consuming practices from prosaic, to having much relevance for research on workplace learning.  相似文献   

4.

Objective

Salmonella enterica remains a major cause of food-borne disease in humans, and Salmonella Typhimurium (ST) contamination of poultry products is a worldwide problem. Since macrophages play an essential role in controlling Salmonella infection, the aim of this study was to evaluate the effect of glycyrrhizic acid (GA) on immune function of chicken HD11 macrophages.

Methods

Chicken HD11 macrophages were treated with GA (0, 12.5, 25, 50, 100, 200, 400, or 800 μg/ml) and lipopolysaccharide (LPS, 500 ng/ml) for 3, 6, 12, 24, or 48 h. Evaluated responses included phagocytosis, bacteria-killing, gene expression of cell surface molecules (cluster of differentiation 40 (CD40), CD80, CD83, and CD197) and antimicrobial effectors (inducible nitric oxide synthase (iNOS), NADPH oxidase-1 (NOX-1), interferon-γ (IFN-γ), LPS-induced tumor necrosis factor (TNF)-α factor (LITAF), interleukin-6 (IL-6), and IL-10), and production of nitric oxide (NO) and hydrogen peroxide (H2O2).

Results

GA increased the internalization of both fluorescein isothiocyanate (FITC)-dextran and ST by HD11 cells and markedly decreased the intracellular survival of ST. We found that the messenger RNA (mRNA) expression of cell surface molecules (CD40, CD80, CD83, and CD197) and cytokines (IFN-γ, IL-6, and IL-10) of HD11 cells was up-regulated following GA exposure. The expression of iNOS and NOX-1 was induced by GA and thereby the productions of NO and H2O2 in HD11 cells were enhanced. Notably, it was verified that nuclear factor-κB (NF-κB) and c-Jun N-terminal kinase (JNK) pathways were responsible for GA-induced synthesis of NO and IFN-γ gene expression.

Conclusions

Taken together, these results suggested that GA exhibits a potent immune regulatory effect to activate chicken macrophages and enhances Salmonella-killing capacity.
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5.
Pore pressure dissipation during piezocone testing provides a unique tool for estimating the hydraulic properties of in-situ backfills in soil-bentonite (SB) slurry trench cutoff walls. Six tests were performed in an SB slurry trench cutoff wall located in Jiangsu Province, China. The pore pressure dissipation curves obtained are non-monotonic, which, as far as the authors are aware, is reported for the first time in SB cutoff walls. The non-monotonic dissipation curves are attributed to the redistribution of excess pore pressures between the base soil clods and the rest of the backfill around the cone. Four existing interpretation methods are adopted to analyze the measured non-monotonic piezocone dissipation curves. The horizontal coefficients of consolidation (ch) of the backfills obtained by three methods are close to each other and in agreement with the results of fixed-ring consolidometer tests, while the other method gives a high overestimate. The hydraulic conductivities (kh) of the backfills are also estimated by four methods, three based on dissipation test results and one based on piezocone penetration data. kh estimated by consolidation theory are close to the results of flexible wall permeameter tests. Two empirical expressions for dissipation tests give relatively low kh, but the method based on penetration gives kh much larger than the laboratory test results.  相似文献   

6.
In this study, we used a simple impregnation method to prepare Fe–Ce–O x catalysts and tested them regarding their low-temperature (200–300 °C) selective catalytic reduction (SCR) of NO using NH3. We investigated the effects of Fe/Ce molar ratio, the gas hourly space velocity (GHSV), the stability and SO2/H2O resistance of the catalysts. The results showed that the FeCe(1:6)O x (Ce/Fe molar ratio is 1:6) catalyst, which has some ordered parallel channels, exhibited good SCR performance. The FeCe(1:6)O x catalyst had the highest NO conversion with an activity of 94–99% at temperatures between 200 and 300 °C at a space velocity of 28,800 h?1. The NO conversion for the FeCe(1:6)O x catalyst also reached 80–98% between 200 and 300 °C at a space velocity of 204,000 h?1. In addition, the FeCe(1:6)O x catalyst demonstrated good stability in a 10-h SCR reaction at 200–300 °C. Even in the presence of SO2 and H2O, the FeCe(1:6)O x catalyst exhibited good SCR performance.  相似文献   

7.
In this paper we will first prove that the nontrivial L p solutions of the vector refinement e-quation exist if and only if the corresponding subdivision scheme with a suitable initial function converges in L p without assumption of the stability of the solutions. Then we obtain a characterization of the convergence of the subdivision scheme in terms of the mask. This gives a complete answer to the existence of L p solutions of the refinement equation and the convergence of the corresponding subdivision schemes.  相似文献   

8.
In plants, lipoxygenases (LOXs) play a crucial role in biotic and abiotic stresses. In our previous study, five 13-LOX genes of oriental melon were regulated by abiotic stress but it is unclear whether the 9-LOX is involved in biotic and abiotic stresses. The promoter analysis revealed that CmLOX09 (type of 9-LOX) has hormone elements, signal substances, and stress elements. We analyzed the expression of CmLOX09 and its downstream genes—CmHPL and CmAOS—in the leaves of four-leaf stage seedlings of the oriental melon cultivar “Yumeiren” under wound, hormone, and signal substances. CmLOX09, CmHPL, and CmAOS were all induced by wounding. CmLOX09 was induced by auxin (indole acetic acid, IAA) and gibberellins (GA3); however, CmHPL and CmAOS showed differential responses to IAA and GA3. CmLOX09, CmHPL, and CmAOS were all induced by hydrogen peroxide (H2O2) and methyl jasmonate (MeJA), while being inhibited by abscisic acid (ABA) and salicylic acid (SA). CmLOX09, CmHPL, and CmAOS were all induced by the powdery mildew pathogen Podosphaera xanthii. The content of 2-hexynol and 2-hexenal in leaves after MeJA treatment was significantly higher than that in the control. After infection with P. xanthii, the diseased leaves of the oriental melon were divided into four levels—levels 1, 2, 3, and 4. The content of jasmonic acid (JA) in the leaves of levels 1 and 3 was significantly higher than that in the level 0 leaves. In summary, the results suggested that CmLOX09 might play a positive role in the response to MeJA through the hydroperoxide lyase (HPL) pathway to produce C6 alcohols and aldehydes, and in the response to P. xanthii through the allene oxide synthase (AOS) pathway to form JA.  相似文献   

9.
A circular jet has broad and important applications in practical engineering. Most research in this area has focused on a free jet, a wall jet or a vertical jet in a bounded domain. In this study, the mean velocities of circular offset jets were studied for four jet exit Froude numbers (Fr), three offset heights (S) (S/d=1, 2, 3) and three submergence ratios (ht/S) (surface jet, mixed jet, and submerged jet) in a bounded basin. Based on the results, we propose a velocity decay formula for a circular jet. The lateral velocity spread was more consistent with Gaussian and Cauchy–Lorentz distributions than the vertical velocity. Moreover, Fr had little effect on the decay of the mean velocity for a circular jet when Re>1×104. The lateral and vertical spreads showed a quadratic relationship with the streamwise distance for different values of Fr at X/d<10. The positions of maximum mean velocity decay were independent of Fr and S/d when X/d<10. The spread rate was more uniform in the lateral direction than that in the vertical direction in a certain region for different S/d and ht/S. Therefore, the decay, spread, and maximum velocity position of the mean velocity for a circular offset jet can remain stable under different values of Fr, offset height, and submergence ratio.  相似文献   

10.

Objective

To investigate a possible association between common variations of the P2RY12 and the residual clopidogrel on-treatment platelet reactivity after adjusting for the influence of CYP2C19 tested by thromboelastography (TEG).

Methods

One hundred and eighty patients with acute coronary syndrome (ACS) treated with clopidogrel and aspirin were included and platelet function was assessed by TEG. Five selected P2RY12 single nucleotide polymorphisms (SNPs; rs6798347, rs6787801, rs6801273, rs6785930, and rs2046934), which cover the common variations in the P2RY12 gene and its regulatory regions, and three CYP2C19 SNPs (*2,*3,*17) were genotyped and possible haplotypes were analyzed.

Results

The high on-treatment platelet reactivity (HTPR) prevalence defined by a platelet inhibition rate <30% by TEG in adenosine diphosphate (ADP)-channel was 69 (38.33%). Six common haplotypes were inferred from four of the selected P2RY12 SNPs (denoted H0 to H5) according to the linkage disequilibrium R square (except for rs2046934). Haplotype H1 showed a significantly lower incidence of HTPR than the reference haplotype (H0) in the total study population while haplotypes H1 and H2 showed significantly lower incidences of HTPR than H0 in the nonsmoker subgroup after adjusting for CYP2C19 effects and demographic characteristics. rs2046934 (T744C) did not show any significant association with HTPR.

Conclusions

The combination of common P2RY12 variations including regulatory regions rather than rs2046934 (T744C) that related to pharmacodynamics of clopidogrel in patients with ACS was independently associated with residual on-clopidogrel platelet reactivity. This is apart from the established association of the CYP2C19. This association seemed more important in the subgroup defined by smoking.
  相似文献   

11.

Objectives

To evaluate the possible photoprotection mechanisms of cyclic and linear electron flux (CEF and LEF) under specific high temperature and high light (HH) stress.

Methods

Six-leaf-stage tomato seedlings (“Liaoyuanduoli”, n=160) were divided into four parts: Part 1, served as control under 25 °C, 500 μmol/(m2·s); Part 2, spayed with distilled water (H2O) under 35 °C, 1000 μmol/(m2·s) (HH); Part 3, spayed with 100 μmol/L diuron (DCMU, CEF inhibitor) under HH; Part 4, spayed with 60 μmol/L methyl viologen (MV, LEF inhibitor) under HH. Energy conversion, photosystem I (PSI), and PSII activity, and trans-thylakoid membrane proton motive force were monitored during the treatment of 5 d and of the recovering 10 d.

Results

HH decreased photochemical reaction dissipation (P) and the maximal photochemical efficiency of PSII (F v/F m), and increased the excitation energy distribution coefficient of PSII (β); DCMU and MV aggravated the partition imbalance of the excitation energy (γ) and the photoinhibition degree. With prolonged DCMU treatment time, electron transport rate and quantum efficiency of PSI (ETRI and Y I) significantly decreased whereas acceptor and donor side limitation of PSI (Y NA and Y ND) increased. MV led to a significant decline and accession of yield of regulated and non-regulated energy Y NPQ and Y NO, respectively. Membrane integrity and ATPase activity were reduced by HH stress, and DCMU and MV enhanced inhibitory actions.

Conclusion

The protective effects of CEF and LEF were mediated to a certain degree by meliorations in energy absorption and distribution as well as by maintenance of thylakoid membrane integrity and ATPase activity.
  相似文献   

12.
This paper presents the matrix representation for the hyperbolic polynomial B-spline basis and the algebraic hyperbolic Bézier basis in a recursive way, which are both generated over the space Θn = span {sinht, cosht, tn?3, …, t, 1} in which n is an arbitrary integer larger than or equal to 3. The conversion matrix from the hyperbolic polynomial B-spline basis of arbitrary order to the algebraic hyperbolic Bézier basis of the same order is also given by a recursive approach. As examples, the specific expressions of the matrix representation for the hyperbolic polynomial B-spline basis of order 4 and the algebraic hyperbolic Bézier basis of order 4 are given, and we also construct the conversion matrix between the two bases of order 4 by the method proposed in the paper. The results in this paper are useful for the evaluation and conversion of the curves and surfaces constructed by the two bases.  相似文献   

13.
Alloying is an effective way to manipulate the composition and physico-chemical properties of functional materials. We demonstrated the syntheses of alloyed Co x Ni1?x O nanocrystals using a nonaqueous approach, with x continuously tuned from 0 to 1 by varying the molar ratios of the cobalt precursor in the reagents. The morphological, structural, and compositional properties of the alloyed Co x Ni1?x O nanocrystals were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), inductively coupled plasma atomic emission spectroscopy (ICP-AES), and energy dispersive X-ray spectroscopy (EDS). The results showed that the cobalt and nickel atoms were homogeneously distributed in the alloyed nanocrystals. The as-prepared Co x Ni1?x O nanocrystals can be applied as the hole-transporting layers in polymer light emitting diodes (PLEDs). Our study provides a good example for the syntheses of alloyed oxide nanocrystals with continuously tunable composition.  相似文献   

14.
An extracellular β-glucosidase produced by Aspergillus terreus was identified, purified, characterized and was tested for the hydrolysis of soybean isoflavone. Matrix-assisted laser desorption/ionization with tandem time-of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF MS) revealed the protein to be a member of the glycosyl hydrolase family 3 with an apparent molecular mass of about 120 kDa. The purified β-glucosidase showed optimal activity at pH 5.0 and 65 °C and was very stable at 50 °C. Moreover, the enzyme exhibited good stability over pH 3.0–8.0 and possessed high tolerance towards pepsin and trypsin. The kinetic parameters Km (apparent Michaelis-Menten constant) and Vmax (maximal reaction velocity) for p-nitrophenyl-β-d-glucopyranoside (pNPG) were 1.73 mmol/L and 42.37 U/mg, respectively. The Km and Vmax for cellobiose were 4.11 mmol/L and 5.7 U/mg, respectively. The enzyme efficiently converted isoflavone glycosides to aglycones, with a hydrolysis rate of 95.8% for daidzin, 86.7% for genistin, and 72.1% for glycitin. Meanwhile, the productivities were 1.14 mmol/(L·h) for daidzein, 0.72 mmol/(L·h) for genistein, and 0.19 mmol/(L·h) for glycitein. This is the first report on the application of A. terreus β-glucosidase for converting isoflavone glycosides to their aglycones in soybean products.  相似文献   

15.
To address the need for effective, efficient ways to apply active learning in undergraduate biology courses, in this paper, we propose a problem-centered approach that utilizes supplemental web-based instructional materials based on principles of active learning. We compared two supplementary web-based modules using active learning strategies: the first used Merrill’s First Principles of Instruction as a framework for organizing multiple active learning strategies; the second used a traditional web-based approach. Results indicated that (a) the First Principles group gained significantly from pretest to posttest at the Remember level (t(40) = ?1.432, p = 0.08, ES = 0.4) and at the Problem Solving level (U = 142.5, N1 = 21, N2 = 21, p = .02, ES = 0.7) and (b) the Traditional group gained significantly from pretest to posttest at the Remember level (t(36) = 1.762, p = 0.043, ES = 0.6). Those in the First Principles group were significantly more likely than the traditional group to be confident in their ability to solve problems in the future (χ2 (2, N = 40) = 3.585, p = 0.09).  相似文献   

16.
Starting with an elementary problem that appeared in the Putnam mathematics competition, we proceed to discuss some techniques of transcendental number theory and prove the following result. If p, q, r are distinct primes and if c is a real number with the property that pc, qc, rc are integers, then c must be a non-negative integer. The tools used are some linear algebra and complex analysis. The zero-density estimate method discussed here was used by Alan Baker to prove his celebrated theorem on linear forms in logarithms. The question as to whether we can replace three primes by two primes is an open question.  相似文献   

17.
In three experiments, we compared the effectiveness of rainbow writing and retrieval practice, two common methods of spelling instruction. In experiment 1 (n?=?14), second graders completed 2 days of spelling practice, followed by spelling tests 1 day and 5 weeks later. A repeated measures analysis of variance demonstrated that spelling accuracy for words trained with retrieval practice was higher than for words trained with rainbow writing on both tests (η p 2 ?=?.49). In experiments 2 (second graders, n?=?16) and 3 (first graders, n?=?12), students completed 2 days of spelling practice followed by a spelling test 1 day later. Results replicated experiment 1; spelling accuracy was higher for words trained with retrieval practice compared with rainbow writing (η p 2 ?=?.42 and .64, respectively). Furthermore, students endorsed both liking and learning from retrieval practice at least as much as (and sometimes more than) rainbow writing. Results demonstrate that retrieval practice is a more useful (and as engaging) training method than is rainbow writing and extend the well-established testing effect to beginning spellers.  相似文献   

18.
Considering the great importance of the elastic shear modulus G0 of unsaturated soils to the serviceability of many geo-structures in geo-energy and geo-environmental engineering, some semi-empirical models have been reported for the G0 of unsaturated soils. Existing models require at least three parameters and the calibration of the model parameters requires extensive time-consuming unsaturated soil tests. In this study, a simple semi-empirical model is proposed for the hysteretic G0 of unsaturated soils, requiring only two parameters. The constitutive variables of the mean Bishop’s stress and a bonding variable are adopted for considering the average stress between soil particles and the additional normal forces between soil particles provided by water menisci. The derived equation is applied to simulate the G0 of unsaturated silts and sands. Comparisons between the measured and calculated results demonstrate that the proposed equation is able to describe the influences of various factors on G0, including mean net stress, suction, wetting-drying, and void ratio.  相似文献   

19.
20.
Measuring gifted and talented (GT) students’ perceptions of their GT label might seem to be a relatively straightforward affair. Most of this research uses survey methods that ask GT students to complete Likert scale or open-ended response questionnaires about their perceptions of the label and then presents results in clear and quantifiable terms, such as “X % of students hold positive perceptions of the GT label.” However, our qualitative study of GT students in two middle school social studies classrooms presents findings that not only trouble, but prompt questions about simple proclamations regarding GT students’ perceptions of the GT label. What we found was that given the opportunity to share their thoughts at length, this group of GT students expressed a range of often contradictory perceptions about their GT label. Students expressed multiple interpretations and perceptions of the GT label, as well as both embraced the label and rejected the label.  相似文献   

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