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1.
The aim of the present study was to examine the effect of ingesting 75?g of glucose 45?min before the start of a graded exercise test to exhaustion on the determination of the intensity that elicits maximal fat oxidation (Fatmax). Eleven moderately trained individuals ( V?O2max: 58.9±1.0?ml?·?kg?1?·?min?1; mean±sx¯ ), who had fasted overnight, performed two graded exercise tests to exhaustion, one 45?min after ingesting a placebo drink and one 45?min after ingesting 75?g of carbohydrate in the form of glucose. The tests started at 95?W and the workload was increased by 35?W every 3?min. Gas exchange measures and heart rate were recorded throughout exercise. Fat oxidation rates were calculated using stoichiometric equations. Blood samples were collected at rest and at the end of each stage of the test. Maximal fat oxidation rates decreased from 0.46±0.06 to 0.33±0.06?g?·?min?1 when carbohydrate was ingested before the start of exercise (P?<0.01). There was also a decrease in the intensity which elicited maximal fat oxidation (60.1±1.9% vs 52.0±3.4% V?O2max) after carbohydrate ingestion (P?<0.05). Maximal power output was higher in the carbohydrate than in the placebo trial (346±12 vs 332±12?W) (P?<0.05). In conclusion, the ingestion of 75?g of carbohydrate 45?min before the onset of exercise decreased Fatmax by 14%, while the maximal rate of fat oxidation decreased by 28%.  相似文献   

2.
The aim of this study was to determine the effects of caffeine ingestion on a ‘preloaded’ protocol that involved cycling for 2?min at a constant rate of 100% maximal power output immediately followed by a 1-min ‘all-out’ effort. Eleven male cyclists completed a ramp test to measure maximal power output. On two other occasions, the participants ingested caffeine (5?mg?·?kg?1) or placebo in a randomized, double-blind procedure. All tests were conducted on the participants' own bicycles using a Kingcycle? test rig. Ratings of perceived exertion (RPE; 6–20 Borg scale) were lower in the caffeine trial by approximately 1 RPE point at 30, 60 and 120?s during the constant rate phase of the preloaded test (P?<0.05). The mean power output during the all-out effort was increased following caffeine ingestion compared with placebo (794±164 vs 750±163?W; P?=?0.05). Blood lactate concentration 4, 5 and 6?min after exercise was also significantly higher by approximately 1?mmol?·?l?1 in the caffeine trial (P?<0.05). These results suggest that high-intensity cycling performance can be increased following moderate caffeine ingestion and that this improvement may be related to a reduction in RPE and an elevation in blood lactate concentration.  相似文献   

3.
The purpose of this study was to examine the influence of a carbohydrate-rich meal on post-prandial metabolic responses and skeletal muscle glycogen concentration. After an overnight fast, eight male recreational/club endurance runners ingested a carbohydrate (CHO) meal (2.5 g CHO?·?kg?1 body mass) and biopsies were obtained from the vastus lateralis muscle before and 3 h after the meal. Ingestion of the meal resulted in a 10.6?±?2.5% (P?<?0.05) increase in muscle glycogen concentration (pre-meal vs post-meal: 314.0?±?33.9 vs 347.3?±?31.3 mmol?·?kg?1 dry weight). Three hours after ingestion, mean serum insulin concentrations had not returned to pre-feeding values (0 min vs 180 min: 45?±?4 vs 143?±?21 pmol?·?l?1). On a separate occasion, six similar individuals ingested the meal or fasted for a further 3 h during which time expired air samples were collected to estimate the amount of carbohydrate oxidized over the 3 h post-prandial period. It was estimated that about 20% of the carbohydrate consumed was converted into muscle glycogen, and about 12 % was oxidized. We conclude that a meal providing 2.5 g CHO?·?kg?1 body mass can increase muscle glycogen stores 3 h after ingestion. However, an estimated 67% of the carbohydrate ingested was unaccounted for and this may have been stored as liver glycogen and/or still be in the gastrointestinal tract.  相似文献   

4.
Abstract

The aim of this study was to investigate the effect of ingesting a carbohydrate-electrolyte solution, during the 90-min Loughborough Intermittent Shuttle Test, on soccer skill performance. Seventeen male soccer players ingested either a 6.4% carbohydrate-electrolyte solution or placebo solution equivalent to 8 ml · kg?1 body mass before exercise and 3 ml · kg?1 body mass after every 15 min of exercise, in a double-blind randomized cross-over design, with the trials separated by 7 days. The evening before the main trial, the participants performed glycogen-reducing exercise on a cycle ergometer (80 min at 70%[Vdot]O2max) and were then fed a low-carbohydrate meal. After a 12-h overnight fast, they performed The Loughborough Soccer Passing Test before and after every 15 min of exercise. Analysis of the combined skill test data showed a significant time effect (P = 0.001) with differences between 0–45 and 75–90 min (P < 0.05). There was a 3% reduction in skill performance from before to after exercise in the carbohydrate-electrolyte trial, whereas in the placebo trial the decrease was 14% (P = 0.07). In conclusion, skill performance during the simulated soccer activity appeared to deteriorate in the last 15–30 min of exercise. However, providing 52 g · h?1 carbohydrate during exercise showed a tendency to better maintain soccer skill performance than a taste-matched placebo.  相似文献   

5.
Abstract

This study investigated the influence of dehydration during soccer-type intermittent exercise on isokinetic and isometric muscle function. Eight soccer players performed two 90-min high-intensity intermittent shuttle-running trials without (NF) or with (FL) fluid ingestion (5 ml · kg?1 before and 2 ml · kg?1 every 15 min). Isokinetic and isometric strength and muscular power of knee flexors and knee extensors were measured pre-exercise, at half-time and post-exercise using isokinetic dynamometry. Sprint performance was monitored throughout the simulated-soccer exercise. Isokinetic knee strength was reduced at faster (3.13 rad · s?1; P = 0.009) but not slower (1.05 rad · s?1; P = 0.063) contraction speeds with exercise; however, there was no difference between FL and NF. Peak isometric strength of the knee extensors (P = 0.002) but not the knee flexors (P = 0.065) was significantly reduced with exercise with no difference between FL and NF. Average muscular power was reduced over time at both 1.05 rad · s?1 (P = 0.01) and 3.14 rad · s?1 (P = 0.033) but was not different between FL and NF. Mean 15-m sprint time increased with duration of exercise (P = 0.005) but was not different between FL and NF. In summary, fluid ingestion during 90 min of soccer-type exercise was unable to offset the reduction in isokinetic and isometric strength and muscular power of the knee extensors and flexors.  相似文献   

6.
Nine male student games players consumed either flavoured water (0.1 g carbohydrate, Na+ 6 mmol · l?1), a solution containing 6.5% carbohydrate-electrolytes (6.5 g carbohydrate, Na+ 21 mmol · l?1) or a taste placebo (Na+ 2 mmol · l?1) during an intermittent shuttle test performed on three separate occasions at an ambient temperature of 30°C (dry bulb). The test involved five 15-min sets of repeated cycles of walking and variable speed running, each separated by a 4-min rest (part A of the test), followed by 60 s run/60 s rest until exhaustion (part B of the test). The participants drank 6.5 ml · kg?1 of fluid as a bolus just before exercise and thereafter 4.5 ml · kg?1 during every exercise set and rest period (19 min). There was a trial order effect. The total distance completed by the participants was greater in trial 3 (8441 ± 873 m) than in trial 1 (6839 ± 512, P < 0.05). This represented a 19% improvement in exercise capacity. However, the trials were performed in a random counterbalanced order and the participants completed 8634 ± 653 m, 7786 ± 741 m and 7099 ± 647 m in the flavoured water (FW), placebo (P) and carbohydrate-electrolyte (CE) trials, respectively (P = 0.08). Sprint performance was not different between the trials but was impaired over time (FW vs P vs CE: set 1, 2.41 ± 0.02 vs 2.39 ± 0.03 vs 2.39 ± 0.03 s; end set, 2.46 ± 0.03 vs 2.47 ± 0.03 vs 2.47 ± 0.02 s; main

effect time, P < 0.01). The rate of rise in rectal temperature was greater in the carbohydrate-electrolyte trial (rise in rectal temperature/duration of trial, °C · h?1; FW vs CE, P < 0.05; P vs CE, N.S.). Blood glucose concentrations were higher in the carbohydrate-electrolyte than in the other two trials (FW vs P vs CE: rest, 4.4 ± 0.1 vs 4.3 ± 0.1 vs 4.2 ± 0.1 mmol · l?1; end of exercise, 5.4 ± 0.3 vs 6.4 ± 0.6 vs 7.2 ± 0.5 mmol · l?1; main effect trial, P < 0.05; main effect time, P < 0.01). Plasma free fatty acid concentrations at the end of exercise were lower in the carbohydrate-electrolyte trial than in the other two trials (FW vs P vs CE: 0.57 ± 0.08 vs 0.53 ± 0.11 vs 0.29 ± 0.04 mmol · l?1; interaction, P < 0.01). The correlation between the rate of rise in rectal temperature (°C · h?1) and the distance completed was ?0.91, ?0.92 and ?0.96 in the flavoured water, placebo and carbohydrate-electrolyte conditions, respectively (P < 0.01). Heart rate, blood pressure, plasma ammonia, blood lactate, plasma volume and rate of perceived exertion were not different between the three fluid trials. Although drinking the carbohydrate-electrolyte solution induced greater metabolic changes than the flavoured water and placebo solutions, it is unlikely that in these unacclimated males carbohydrate availability was a limiting factor in the performance of intermittent running in hot environmental conditions.  相似文献   

7.
This study examined the effects of different work?–?rest durations during 40?min intermittent treadmill exercise and subsequent running performance. Eight males (mean?±?s: age 24.3?±?2.0 years, body mass 79.4?±?7.0?kg, height 1.77?±?0.05?m) undertook intermittent exercise involving repeated sprints at 120% of the speed at which maximal oxygen uptake (v-[Vdot]O2max) was attained with passive recovery between each one. The work?–?rest ratio was constant at 1:1.5 with trials involving short (6:9?s), medium (12:18?s) or long (24:36?s) work?–?rest durations. Each trial was followed by a performance run to volitional exhaustion at 150% v-[Vdot]O2max. After 40?min, mean exercise intensity was greater during the long (68.4?±?9.3%) than the short work?–?rest trial (54.9?±?8.1% [Vdot]O2max; P?<?0.05). Blood lactate concentration at 10?min was higher in the long and medium than in the short work?–?rest trial (6.1?±?0.8, 5.2?±?0.9, 4.5?±?1.3?mmol?·?l?1, respectively; P?<?0.05). The respiratory exchange ratio was consistently higher during the long than during the medium and short work?–?rest trials (P <?0.05). Plasma glucose concentration was higher in the long and medium than in the short work?–?rest trial after 40?min of exercise (5.6?±?0.1, 6.6?±?0.2 and 5.3?±?0.5?mmol?·?l?1, respectively; P?<?0.05). No differences were observed between trials for performance time (72.7?±?14.9, 63.2?±?13.2, 57.6?±?13.5?s for the short, medium and long work?–?rest trial, respectively; P = 0.17), although a relationship between performance time and 40?min plasma glucose was observed (P?<?0.05). The results show that 40?min of intermittent exercise involving long and medium work?–?rest durations elicits greater physiological strain and carbohydrate utilization than the same amount of intermittent exercise undertaken with a short work?–?rest duration.  相似文献   

8.
Abstract

The aim of this study was to assess the effect of caffeine ingestion on 8 km run performance using an ecologically valid test protocol. A randomized double-blind crossover study was conducted involving eight male distance runners. The participants ran an 8 km race 1 h after ingesting a placebo capsule, a caffeine capsule (3 mg · kg?1 body mass) or no supplement. Heart rate was recorded at 5 s intervals throughout the race. Blood lactate concentration and ratings of perceived exertion were recorded after exercise. A repeated-measures analysis of variance (ANOVA) identified a significant treatment effect for 8 km performance time (P < 0.05); caffeine resulted in a mean improvement of 23.8 s (95% confidence interval [CI] = 13.1 to 34.5 s) in 8 km performance time (1.2% improvement, 95% CI = 0.7 to 1.8%). In addition, a two-way (time × condition) repeated-measures ANOVA identified a significantly higher blood lactate concentration 3 min after exercise during the caffeine trial (P < 0.05). We conclude that ingestion of 3 mg · kg?1 body mass of caffeine can improve absolute 8 km run performance in an ecologically valid race setting.  相似文献   

9.
High Intensity Interval Training (HIIT) can be performed with different effort to rest time-configurations, and this can largely influence training responses. The purpose of the study was to compare the acute physiological responses of two HIIT and one moderate intensity continuous training (MICT) protocol in young men. A randomised cross-over study with 10 men [age, 28.3?±?5.5years; weight, 77.3?±?9.3?kg; height, 1.8?±?0.1?m; peak oxygen consumption (VO2peak), 44?±?11?mL.kg?1.min?1]. Participants performed a cardiorespiratory test on a treadmill to assess VO2peak, velocity associated with VO2peak (vVO2peak), peak heart rate (HRpeak) and perceived exertion (RPE). Then participants performed three protocols equated by distance: Short HIIT (29 bouts of 30s at vVO2peak, interspersed by 30s of passive recovery, 29?min in total), Long HIIT (3 bouts of 4?min at 90% of vVO2peak, interspersed by 3?min of recovery at 60% of vVO2peak, 21?min in total) and MICT (21?min at 70% of vVO2peak). The protocols were performed in a randomised order with ≥48 h between them. VO2, HRpeak and RPE were compared. VO2peak in Long HIIT was significantly higher than Short HIIT and MICT (43?±?11 vs 32?±?8 and 37?±?8?mL.kg?1.min?1, respectively, P?P?P?2, HR and RPE than Short HIIT and MICT, suggesting a higher demand on the cardiorespiratory system. Short HIIT and MICT presented similar physiologic and perceptual responses, despite Short HIIT being performed at higher velocities.  相似文献   

10.
Abstract

The current study examined the effect of acute caffeine ingestion on mean and peak power production, fatigue index and rating of perceived exertion (RPE) during upper body and lower body Wingate anaerobic test (WANT) performance. Using a double-blind design, 22 males undertook one upper body and one lower body WANT, 60?min following ingestion of caffeine (5?mg*kg?1) and one upper body and one lower body WANT following ingestion of placebo (5?mg*kg?1 Dextrose). Peak power was significantly higher (P?=?.001) following caffeine ingestion in both upper and lower body WANT. Peak power and mean power was also significantly higher during lower body, compared to upper body WANTs irrespective of substance ingested. However, caffeine ingestion did not enhance mean power neither in upper nor lower-body WANT. There were no significant differences in mean fatigue index as a consequence of substance ingested or mode of exercise (all P?>?0.05). For RPE there was also a significant substance ingested X mode interaction (P?=?.001) where there were no differences in RPE between caffeine and placebo conditions in lower body WANTs but significantly lower RPE during upper body WANT in the presence of caffeine compared to placebo (P?=?.014). This is the first study to compare the effects of caffeine ingestion on upper and lower body 30-second WANT performance and suggests that caffeine ingestion in the dose of 5?mg*kg?1 ingested 60?min prior to exercise significantly enhances peak power when data from upper and lower body WANTs are combined.  相似文献   

11.
This study examined the separate and combined effects of heat acclimation and hand cooling on post-exercise cooling rates following bouts of exercise in the heat. Seventeen non-heat acclimated (NHA) males (mean ± SE; age, 23 ± 1 y; mass, 75.30 ± 2.27 kg; maximal oxygen consumption [VO2 max], 54.1 ± 1.3 ml·kg?1·min?1) completed 2 heat stress tests (HST) when NHA, then 10 days of heat acclimation, then 2 HST once heat acclimated (HA) in an environmental chamber (40°C; 40%RH). HSTs were 2 60-min bouts of treadmill exercise (45% VO2 max; 2% grade) each followed by 10 min of hand cooling (C) or no cooling (NC). Heat acclimation sessions were 90–240 min of treadmill or stationary bike exercise (60–80% VO2 max). Repeated measures ANOVA with Fishers LSD post hoc (α < 0.05) identified differences. When NHA, C (0.020 ± 0.003°C·min?1) had a greater cooling rate than NC (0.013 ± 0.003°C·min?1) (mean difference [95%CI]; 0.007°C [0.001,0.013], P = 0.035). Once HA, C (0.021 ± 0.002°C·min?1) was similar to NC (0.025 ± 0.002°C·min?1) (0.004°C [?0.003,0.011], P = 0.216). Hand cooling when HA (0.021 ± 0.002°C·min?1) was similar to when NHA (0.020 ± 0.003°C·min?1) (P = 0.77). In conclusion, when NHA, C provided greater cooling rates than NC. Once HA, C and NC provided similar cooling rates.  相似文献   

12.
Nine well-trained, unacclimatized female hockey players performed the Loughborough Intermittent Shuttle Test (LIST) interspersed with three field hockey skill tests in hot (30°C, 38% relative humidity) and moderate (19°C, 51% relative humidity) environmental conditions. Field hockey skill performance declined in both the hot and moderate conditions following 30 and 60?min of the LIST compared with pre-LIST values (P <?0.01). This decrement in performance was compounded in the hot environment with a 6% poorer performance in the heat recorded for the second skill test at 30?min (P <?0.05, hot 101.7?±?3.6 vs moderate 95.7?±?2.9?s; mean ±?s x). However, no difference was found in the decision-making element of the skill test. Fifteen-metre sprint times were slower in the hot condition (P <?0.01). In the hot environment, rectal temperature (P?<?0.01), perceived exertion (P?<?0.05), perceived thirst (P?<?0.01), blood glucose concentration (P?<?0.05) and serum aldosterone concentration (P?<?0.01) were higher. Estimated mean (?±?s x) sweat rate was higher in the hot trial (1.27?±?0.10?l?·?h?1) than in the moderate trial (1.05?±?0.12?l?·?h?1) (P?<?0.05). Body mass was well maintained in both trials. No differences in serum cortisol, blood lactate, plasma volume or plasma ammonia concentrations were found. These results demonstrate that field hockey skill performance is decreased following intermittent high-intensity shuttle running and that this decrease is greater in hot environmental conditions. The exact mechanism for this decrement in performance remains to be elucidated, but is unlikely to be due to low glycogen concentration or dehydration.  相似文献   

13.
Abstract

Ten healthy, non-cycling trained males (age: 21.2 ± 2.2 years, body mass: 75.9 ± 13.4 kg, height: 178 ± 6 cm, [Vdot]O2PEAK: 46 ± 10 ml · kg?1 · min?1) performed a graded incremental exercise test, two familiarisation trials and six experimental trials. Experimental trials consisted of cycling to volitional exhaustion at 100%, 110% and 120% WPEAK, 60 min after ingesting either 0.3 g · kg?1 body mass sodium bicarbonate (NaHCO3) or 0.1 g · kg?1 body mass sodium chloride (placebo). NaHCO3 ingestion increased cycling capacity by 17% at 100% WPEAK (327 vs. 383 s; P = 0.02) although not at 110% WPEAK (249 vs. 254 s; P = 0.66) or 120% WPEAK (170 vs. 175 s; P = 0.60; placebo and NaHCO3 respectively). Heart rate (P = 0.02), blood lactate (P = 0.001), pH (P < 0.001), [HCO3 ?], (P < 0.001), and base excess (P < 0.001) were greater in all NaHCO3 trials. NaHCO3 attenuated localised ratings of perceived exertion (RPEL) to a greater extent than placebo only at 100% WPEAK (P < 0.02). Ratings of abdominal discomfort and gut fullness were mild but higher for NaHCO3. NaHCO3 ingestion significantly improves continuous constant load cycling at 100% WPEAK due to, in part, attenuation of RPEL.  相似文献   

14.
The purpose of this study was to evaluate two practical interval training protocols on cardiorespiratory fitness, lipids and body composition in overweight/obese women. Thirty women (mean ± SD; weight: 88.1 ± 15.9 kg; BMI: 32.0 ± 6.0 kg · m2) were randomly assigned to ten 1-min high-intensity intervals (90%VO2 peak, 1 min recovery) or five 2-min high-intensity intervals (80–100% VO2 peak, 1 min recovery) or control. Peak oxygen uptake (VO2 peak), peak power output (PPO), body composition and fasting blood lipids were evaluated before and after 3 weeks of training, completed 3 days per week. Results from ANCOVA analyses demonstrated no significant training group differences for any primary variables (P > 0.05). When training groups were collapsed, 1MIN and 2MIN resulted in a significant increase in PPO (?18.9 ± 8.5 watts; P = 0.014) and time to exhaustion (?55.1 ± 16.4 s; P = 0.001); non-significant increase in VO2 peak (?2.36 ± 1.34 ml · kg?1 · min?1; P = 0.185); and a significant decrease in fat mass (FM) (??1.96 ± 0.99 kg; P = 0.011). Short-term interval exercise training may be effective for decreasing FM and improving exercise tolerance in overweight and obese women.  相似文献   

15.
Abstract

This study examined the effects of combined glucose and sodium bicarbonate ingestion prior to intermittent exercise. Ninemales (mean ± s age 25.4 ± 6.6 years, body mass 78.8 ± 12.0 kg, maximal oxygen uptake ([Vdot]O2max) 47.0 ± 7ml · kg · min?1) undertook 4 × 45 min intermittent cycling trials including 15 × 10 s sprints one hour after ingesting placebo (PLA), glucose (CHO), sodium bicarbonate (NaHCO3) or a combined CHO and NaHCO3 solution (COMB). Post ingestion blood pH (7.45 ± 0.03, 7.46 ± 0.03, 7.32 ± 0.05, 7.32 ± 0.01) and bicarbonate (30.3 ± 2.1, 30.7 ± 1.8, 24.2 ± 1.2, 24.0 ± 1.8 mmol · l?1) were greater for NaHCO3 and COMB when compared to PLA and CHO, remaining elevated throughout exercise (main effect for trial; P < 0.05). Blood lactate concentration was greatest throughout exercise for NaHCO3 and COMB (main effect for trial; P < 0.05). Blood glucose concentration was greatest 15 min post-ingestion for CHO followed by COMB, NaHCO3 and PLA (7.13 ± 0.60, 5.58 ± 0.75, 4.51 ± 0.56, 4.46 ± 0.59 mmol · l?1, respectively; P < 0.05). Gastrointestinal distress was lower during COMB compared to NaHCO3 at 15 min post-ingestion (P < 0.05). No differences were observed for sprint performance between trials (P = 1.00). The results of this study suggest that a combined CHO and NaHCO3 beverage reduced gastrointestinal distress and CHO availability but did not improve performance. Although there was no effect on performance an investigation of the effects in more highly trained individuals may be warranted.  相似文献   

16.
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17.
Abstract

The purpose of this study was to compare the effects of two practical precooling techniques (skin cooling vs. skin + core cooling) on cycling time trial performance in warm conditions. Six trained cyclists completed one maximal graded exercise test ([Vdot]O2peak 71.4 ± 3.2 ml · kg?1 · min?1) and four ～40 min laboratory cycling time trials in a heat chamber (34.3°C ± 1.1°C; 41.2% ± 3.0% rh) using a fixed-power/variable-power format. Cyclists prepared for the time trial using three techniques administered in a randomised order prior to the warm-up: (1) no cooling (control), (2) cooling jacket for 40 min (jacket) or (3) 30-min water immersion followed by a cooling jacket application for 40 min (combined). Rectal temperature prior to the time trial was 37.8°C ± 0.1°C in control, similar in jacket (37.8°C ± 0.3°C) and lower in combined (37.1°C ± 0.2°C, P < 0.01). Compared with the control trial, time trial performance was not different for jacket precooling (?16 ± 36 s, ?0.7%; P = 0.35) but was faster for combined precooling (?42 ± 25 s, ?1.8%; P = 0.009). In conclusion, a practical combined precooling strategy that involves immersion in cool water followed by the use of a cooling jacket can produce decrease in rectal temperature that persist throughout a warm-up and improve laboratory cycling time trial performance in warm conditions.  相似文献   

18.
The purpose of this study was to develop a multiple linear regression model to predict treadmill VO2max scores using both exercise and non-exercise data. One hundred five college-aged participants (53 male, 52 female) successfully completed a submaximal cycle ergometer test and a maximal graded exercise test on a motorized treadmill. The submaximal cycle protocol required participants to achieve a steady-state heart rate equal to at least 70% of age-predicted maximum heart rate (220-age), while the maximal treadmill graded exercise test required participants to exercise to volitional fatigue. Relevant submaximal cycle ergometer test data included a mean (±SD) ending steady-state heart rate and ending workrate equal to 164.2 ± 13.0 bpm and 115.3 ± 27.0 watts, respectively. Relevant non-exercise data included a mean (±SD) body mass (kg), perceived functional ability score, and physical activity rating score of 74.2 ± 15.1, 15.7 ± 4.3, and 4.7 ± 2.1, respectively. Multiple linear regression was used to generate the following prediction of (R = .91, standard error of estimates (SEE) = 3.36 ml·kg?1·min?1): VO2max = 54.513 + 9.752 (gender, 1 = male, 0 = female) – .297 (body mass, kg) + .739 (perceived functional ability, 2–26) + .077 (work rate, watts) – .072 (steady-state heart rate). Each predictor variable was statistically significant (p < .05) with beta weights for gender, body mass, perceived functional ability, exercise workrate, and steady-state heart rate equal to .594, –.544, .388, .305, and –.116, respectively. The predicted residual sums of squares (PRESS) statistics reflected minimal shrinkage (RPRESS = .90, SEEPRESS = 3.56 ml·kg?1·min?1) for the multiple linear regression model. In summary, the submaximal cycle ergometer protocol and accompanying prediction model yield relatively accurate VO2max estimates in healthy college-aged participants using both exercise and non-exercise data.  相似文献   

19.
Strenuous physical exercise of the limb muscles commonly results in damage, especially when that exercise is intense, prolonged and includes eccentric contractions. Many factors contribute to exercise-induced muscle injury and the mechanism is likely to differ with the type of exercise. Competitive sports players are highly susceptible to this type of injury. AM3 is an orally administered immunomodulator that reduces the synthesis of proinflammatory cytokines and normalizes defective cellular immune fractions. The ability of AM3 to prevent chronic muscle injury following strenuous exercise characterized by eccentric muscle contraction was evaluated in a double-blind and randomized pilot study. Fourteen professional male volleyball players from the First Division of the Spanish Volleyball League volunteered to take part. The participants were randomized to receive either placebo (n?=?7) or AM3 (n?=?7). The physical characteristics (mean±s) of the placebo group were as follows: age 25.7±2.1 years, body mass 87.2±4.1?kg, height 1.89±0.07?m, maximal oxygen uptake 65.3±4.2?ml?·?kg?1?·?min?1. Those of the AM3 group were as follows: age 26.1±1.9 years, body mass 85.8±6.1?kg, height 1.91±0.07?m, maximal oxygen uptake 64.6±4.5?ml?·?kg?1?·?min?1. All participants were evaluated for biochemical indices of muscle damage, including concentrations of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatine kinase (CK) and its MB fraction (CK-MB), myoglobin, lactate dehydrogenase, urea, creatinine and γ-glutamyltranspeptidase, both before and 30 days after treatment (over the peak of the competitive season). In the placebo group, competitive exercise (i.e. volleyball) was accompanied by significant increases in creatine kinase (494±51 to 560±53?IU?·?l?1, P?<?0.05) and myoglobin (76.8±2.9 to 83.9±3.1?μg?·?l?1, P?<?0.05); aspartate aminotransferase (30.8±3.0 to 31.1±2.9?IU?·?l?1) and lactate dehydrogenase (380±31 to 376±29?IU?·?l?1) were relatively unchanged after the 30 days maximum effort. AM3 not only inhibited these changes, it led to a decrease from baseline serum concentrations of creatine kinase (503±49 to 316±37?IU?·?l?1, P?<?0.05) and myoglobin (80.1±3.2 to 44.1±2.6?IU?·?l?1, P?<?0.05), as well as aspartate aminotransferase (31.1±3.3 to 26.1±2.7?IU?·?l?1, P?<?0.05) and lactate dehydrogenase (368±34 to 310±3?IU?·?l?1, P?<?0.05). The concentration of CK-MB was also significantly decreased from baseline with AM3 treatment (11.6±1.2 to 5.0±0.7?IU?·?l?1, P?<?0.05), but not with placebo (11.4±1.1 to 10.8±1.4?IU?·?l?1). In conclusion, the use of immunomodulators, such as AM3, by elite sportspersons during competition significantly reduces serum concentrations of proteins associated with muscle damage.  相似文献   

20.
Carbohydrate (CHO) availability during endurance exercise seems to attenuate exercise-induced perturbations of cellular homeostasis and might consequently diminish the stimulus for training adaptation. Therefore, a negative effect of CHO intake on endurance training efficacy seems plausible. This study aimed to test the influence of carbohydrate intake on the efficacy of an endurance training program on previously untrained healthy adults. A randomized cross-over trial (8-week wash-out period) was conducted in 23 men and women with two 8-week training periods (with vs. without intake of 50g glucose before each training bout). Training intervention consisted of 4x45 min running/walking sessions/week at 70% of heart rate reserve. Exhaustive, ramp-shaped exercise tests with gas exchange measurements were conducted before and after each training period. Outcome measures were maximum oxygen uptake (VO2max) and ventilatory anaerobic threshold (VT). VO2max and VT increased after training regardless of CHO intake (VO2max: Non-CHO 2.6 ± 3.0 ml*min?1*kg?1 p = 0.004; CHO 1.4 ± 2.5 ml*min?1*kg?1 p = 0.049; VT: Non-CHO 4.2 ± 4.2 ml*min?1*kg?1 p < 0.001; CHO 3.0 ± 4.2 ml*min?1*kg?1 p = 0.003). The 95% confidence interval (CI) for the difference between conditions was between +0.1 and +2.1 ml*min?1*kg?1 for VO2max and between ?1.2 and +3.1 for VT. It is concluded that carbohydrate intake could potentially impair the efficacy of an endurance training program.  相似文献   

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