共查询到18条相似文献，搜索用时 109 毫秒
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心脏重塑主要表现为心肌细胞肥大、细胞外间质重塑。细胞因子、基质金属蛋白酶家族对心肌间质重塑发挥较大的作用,参与了运动性心脏重塑的生理病理发展过程。近年来许多研究致力于阐明运动性心肌间质和血管重塑之间的关系。 相似文献
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采用文献资料法,对降钙素基因相关肽(CGRP)及其与运动心脏重塑的研究进行回顾和总结。结果表明:心脏中存在CGRP阳性神经纤维及CGRP受体,这些神经纤维主要来自脊髓背根神经节细胞。通过对运动心脏重塑的机制、运动与CGRP的关系、CGRP的生理作用、CGRP的信号传导途径、细胞培养、分子生物学等方面的研究总结,认为CGRP是维持机体血流动力学稳定的重要代偿因子,是运动心脏重塑的重要介质。 相似文献
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肾上腺髓质素在运动心脏重塑中的作用 总被引：1，自引：0，他引：1
采用文献综述法，对肾上腺髓质素及其与运动心脏重塑的关系进行探讨，分析了肾上腺髓质素在运动心脏重塑中的作用。通过对运动心脏重塑的机制、运动与肾上腺髓质素的关系、肾上腺髓质素的生理作用、肾上腺髓质素的信号传导、分子生物学等方面的研究，认为肾上腺髓质素是维护机体血液动力学稳定的重要因素，是运动心脏重塑的重要介质。 相似文献
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过度训练症候群与细胞因子学说 总被引：4，自引：0，他引：4
本文对现今的关于OTS的主要学说作了简要的概话,其中包括神经内分泌学说、谷酰胺学说、氨基酸色氨酸减少学说、糖原学说、训练单调学说、细胞因子学说等.并且详细的阐述了OTS与细胞因子的关系. 相似文献
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白细胞介素31(IL-31)是白介素6细胞因子家族新成员,IL-31R是由 IL-31Rα与制瘤素M受体β组成的异源二聚体,IL-31-IL-31R主要通过STAT1、2、3,JAK1、2,P13K/AKT途径和MPAK通路来进行信号转导发挥重要的生物学效应。最近的研究证实IL-31在哮喘的发病机制发挥了重要作用,它有望成为哮喘治疗的潜在靶点。 相似文献
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C1q/肿瘤坏死因子相关蛋白3(C1 q/tumornecrosis factor related protein3,CTRP3)是C1q肿瘤坏死因子相关蛋白家族中的一员,与脂联素具有结构同源性的脂肪因子.近年来发现,CTRP3在心脏保护、促血管生成作用方面发挥着重要的作用,因此,对CTRP3的来源、结构、分布状况及其在心肌梗死、心肌线粒体、主动脉狭窄等心肌保护方面的作用,和血管生成中的生物学功能;以及在运动干预条件下,CTRP3在心脏保护和血管新生作用方面的效应,及其相关作用信号通路进行综述. 相似文献
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心肌营养素-1(CT-1)是新近发现的促心肌肥大因子,除了有利于心脏发育并对心脏起一定的保护作用外,最主要的功能是通过作用于心肌细胞及促成纤维细胞生长和胶原合成来参与和调节心肌肥大。本文从其结构功能及引起心肌肥大的信号转导等方面对其导致的心肌肥大的生物学机制作以综述。 相似文献
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心脏局部RAS与运动心脏重塑之关系 总被引：3，自引：0，他引：3
采用文献综述研究方法,分析了心脏局部RAS与运动心脏重塑之关系,探讨了心脏局部RAS调节运动心脏重塑的机制。提出了心脏局部RAS在运动心脏重塑中有待研究的问题。 相似文献
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一剑倾心家族
一剑倾心家族2007年11月成立。从最初的40多人发展到近600人。现已发展成一剑倾心家族联盟，在QQ游戏中国象棋旧区有华山、泰山、嵩山三个分族，在中国象棋新区有楚水缘、聚义堂两个分族。 相似文献
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Heart rate variability estimates cardiac autonomic modulation, but the relationship between habitual physical activity and heart rate variability remains unclear. The aims of this study were to compare RR-interval and heart rate variability indices in individuals of different habitual physical activity levels, and examine the relationship between habitual physical activity and heart rate variability. Ninety-two healthy volunteers (47 men, 45 women; mean age 23.1 years, s = 2.1) were divided into tertiles according to the Baecke Questionnaire score. Standard heart rate variability indices were derived from 5-min resting RR-interval recordings with paced respiration (0.25 Hz). Between-group differences and the relationship between habitual physical activity and heart rate variability were assessed. More active participants (tertiles 2-3) had longer RR-intervals than those in tertile 1 (P < 0.05). Participants in tertile 2 had higher root mean squared differences of successive normal RR-intervals than those in tertile 1 and a higher standard deviation of normal RR-intervals than those in tertiles 1 and 3. There was a positive linear relationship between habitual activity and RR-interval. Differing RR-interval lengths were found in subgroups of young individuals according to level of habitual physical activity. More active individuals showed resting bradycardia without evidence of enhanced cardiac parasympathetic modulation. The mechanism linking habitual physical activity and RR-interval length appears to be independent of physiological mechanisms that can be measured by heart rate variability. 相似文献
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竞技运动异化论逻辑起点商榷 总被引：7，自引：1，他引：6
黄璐 《天津体育学院学报》2008,23(3):239-242
收集相关文献资料,理论与实证相结合,质疑当前学界日益高涨的竞技运动异化论,对重塑竞技运动异化论逻辑起点进行商榷,商榷观点为:谨慎考察事物的本性,遵循事物由"善"起源(具有阶段性特点)向"恶"发展过程中单一的思维判断理路. 相似文献
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Conconi et al. (1982) reported that an observed deviation from linearity in the heart rate-running velocity relationship determined during a field test in runners coincided with the ‘lactate threshold’. The aim of this study was to assess the validity of the original Conconi test using conventional incremental and constant-load laboratory protocols. Fourteen trained male distance runners (mean ± s : age 22.6 ±3.4 years; body mass 67.6±4.8 kg; peak [Vdot] O 2 66.3 ± 4.7 ml kg -1 min -1) performed a standard multi-stage test for determination of lactate turnpoint and a Conconi test on a motorized treadmill. A deviation from linearity in heart rate was observed in nine subjects. Significant differences were found to exist between running velocity at the lactate turnpoint (4.39 ± 0.20 ms -1) and at deviation from linear heart rate (5.08 ± 0.25 ms -1) (P < 0.01), and between heart rate at the lactate turnpoint (172 ± 10 beats min -1) and at deviation from linearity (186 ± 9 beats min -1) (P < 0.01). When deviation of heart rate from linearity was evident, it occurred at a systematically higher intensity than the lactate turnpoint and at approximately 95% of maximum heart rate. These results were confirmed by the physiological responses of seven subjects, who performed two constant-velocity treadmill runs at 0.14 ms -1 below the running velocity at the lactate turnpoint and that at which the heart rate deviated from linearity. For the lactate turnpoint trial, the prescribed 30 min exercise period was completed by all runners (terminal blood lactate concentration of 2.4 ± 0.5 mM ), while the duration attained in the trial for which heart rate deviated from linearity was 15.9 ± 6.7 min (terminal blood lactate concentration of 8.1 ± 1.8 mM). We concluded that the Conconi test is invalid for the non-invasive determination of the lactate turnpoint and that the deviation of heart rate from linearity represents the start of the plateau at maximal heart rate, the expression of which is dependent upon the specifics of the Conconi test protocol. 相似文献
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中华武术与诗歌作为中国传统文化之载体,在它们的发展进程中,有其同源性。文章在查阅大量文献的基础上,对诗歌中所蕴涵的鏖战豪情、尚武爱国等军事武术文化意境进行研究,旨在丰富中华武术文化,使中华武术真正成为重塑中华民族精神的工具,成为联系中外文化的桥梁。 相似文献
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Keytel LR Goedecke JH Noakes TD Hiiloskorpi H Laukkanen R van der Merwe L Lambert EV 《Journal of sports sciences》2005,23(3):289-297
The aims of this study were to quantify the effects of factors such as mode of exercise, body composition and training on the relationship between heart rate and physical activity energy expenditure (measured in kJ x min(-1)) and to develop prediction equations for energy expenditure from heart rate. Regularly exercising individuals (n = 115; age 18-45 years, body mass 47-120 kg) underwent a test for maximal oxygen uptake (VO2max test), using incremental protocols on either a cycle ergometer or treadmill; VO2max ranged from 27 to 81 ml x kg(-1) x min(-1). The participants then completed three steady-state exercise stages on either the treadmill (10 min) or the cycle ergometer (15 min) at 35%, 62% and 80% of VO2max, corresponding to 57%, 77% and 90% of maximal heart rate. Heart rate and respiratory exchange ratio data were collected during each stage. A mixed-model analysis identified gender, heart rate, weight, V2max and age as factors that best predicted the relationship between heart rate and energy expenditure. The model (with the highest likelihood ratio) was used to estimate energy expenditure. The correlation coefficient (r) between the measured and estimated energy expenditure was 0.913. The model therefore accounted for 83.3% (R2) of the variance in energy expenditure in this sample. Because a measure of fitness, such as VO2max, is not always available, a model without VO2max included was also fitted. The correlation coefficient between the measured energy expenditure and estimates from the mixed model without VO2max was 0.857. It follows that the model without a fitness measure accounted for 73.4% of the variance in energy expenditure in this sample. Based on these results, we conclude that it is possible to estimate physical activity energy expenditure from heart rate in a group of individuals with a great deal of accuracy, after adjusting for age, gender, body mass and fitness. 相似文献
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李可言 《哈尔滨体育学院学报》2000,(2)
通过心率的控制和血乳酸的判定来了解自行车运动员进行一般身体素质训练和专项训练时心率和乳酸的关系,大的负荷阻力对乳酸的产生起重要作用,而心血管能力对供能以及乳酸的清除有着很重要的作用。 相似文献
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采用RPE评分、运动成绩测试、心肺功能测试及心脏内分泌激素放射免疫法检测等方法对运动员心脏功能进行跟踪观察。结果表明：(1)穴位离子导入能明显改善运动员的主观感觉，提高专项成绩，改善心肺功能，降低无氧闲心率，提高有氧耐力，推迟心源性运动性疲劳的发生；(2)穴位离子导入可改善运动员心脏神经肽ET和CGRP的分泌，使之向更有利于适应运动负荷的方向发展。结论是：(1)心源性运动性疲劳的发生与多因素相关；(2)穴位离子导入能多环节、多层面地保护心肌和改善心脏功能，从而延缓疲劳产生和促进疲劳消除。 相似文献