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1.
陈杜鹃  王青 《考试周刊》2015,(33):195-196
为了探讨肠易激综合征(IBS)及其亚型与幽门螺杆菌(HP)感染的关系,本研究随机选取120例IBS患者为实验组,120例健康体检者为对照组,通过14C尿素呼气试验及快速尿素酶法,分析肠易激综合征及各亚型患者的幽门螺杆菌感染情况并将HP阳性的IBS患者各亚型随机分为观察组与对照组,两组同时给予匹维溴铵、蒙脱石治疗4周,观察组加用HP药物治疗2周,观察其疗效。结果表明,实验组(IBS组)HP阳性率60.8%(73/120)高于对照组(健康体检者)45%(54/120),差异有统计学意义;IBS各亚型患者HP感染率分别为:便秘型47.3%(9/19)、腹泻型75%(12/16)、混合型75%(12/16)、未定型58%(40/69),差异有统计学意义;HP阳性IBS各亚型患者:腹泻型观察组治疗总有效率(83.3%),明显高于对照组(33.3%),差异有统计学意义(P<0.05),便秘型观察组治疗总有效率(50%),明显高于对照组(20%),差异有统计学意义(P<0.05),混合型观察组治疗总有效率(83.3%),明显高于对照组(33.3%),差异有统计学意义(P<0.05),未定型观察组治疗总有效率(80%),明显高于对照组(45%),差异有统计学意义(P<0.05)。这说明HP感染与肠易激综合征之间有一定关系,根除HP可能在IBS治疗中起一定作用。  相似文献   

2.
肠易激综合征是以腹部不适或腹痛,伴有排便次数或大便性质改变为特征的常见肠道病,是易反复发作的一组多因素引起的异质性的功能性肠病。根据临床表现的特点,可分为腹泻型、便秘型、腹泻便秘交替型等。因此,对不同的个体应遵循个体化原则进行分析。其发病的原因仍未完全明了,可能原因有:胃肠动力学障碍;内脏感知功能异常;精神焦虑、抑郁和睡眠障碍;肠道感染或肠道菌群失调;  相似文献   

3.
腹泻、便秘等"着急事儿",谁都可能遇上过,一般人常会误认为是吃得不对头了,吃点药对症治疗一下也就过去了。其实并非完全如此,专家指出,腹泻、便秘很可能和人的"心理因素"有关,有些人平时正常饮食,更没吃不干净的东西,但也不时发生腹痛、腹胀、腹泻或便秘,尤其是在情绪紧张和焦虑的时候,那就很可能是患上了一种名为"肠易激综合征"的疾病。  相似文献   

4.
研究目的:明确腹泻型肠易激综合征患者是否具有肠道和躯体高敏感、自主心血管功能紊乱以及肠道低浓度炎症。创新要点:发现腹泻型肠易激综合征患者具有自主心血管功能紊乱和肠道低浓度炎症(这两方面在之前研究中尚存争议)。此外,发现腹泻型肠易激综合征患者的肠道高敏感和躯体高敏感、肠道高敏感和自主心血管功能紊乱、躯体高敏感和自主心血管紊乱之间存在相关性,为患者的治疗提供参考。研究方法:2013年9月至2014年5月,62名腹泻型肠易激综合征患者和20名健康志愿者参与到了本研究。所有受试者接受并顺利完成了相关检查和问卷填写。利用恒压器(渐至极限法)检查我们发现腹泻型肠易激综合征患者具有肠道高敏感。同时,采用冷水刺激法和缺血刺激法探明腹泻型肠易激综合征患者具有躯体高敏感。重要结论:腹泻型肠易激综合征患者具有肠道和躯体高敏感、自主心血管功能紊乱以及肠道低浓度炎症。肠道高敏感和躯体高敏感、肠道高敏感和自主心血管功能紊乱、躯体高敏感和自主心血管紊乱之间存在相关性。  相似文献   

5.
肠易激综合征(IBS)属于胃肠道功能紊乱性疾病,是一组包括腹痛、腹胀伴排便习惯和大便性状异常、粘液便持续存在或间歇发作,而又缺乏形态学和生化指标异常的症候群。我们通过调查IBS患者各系统应激症状及性格取向,进一步探讨IBS发生机制,为临床治疗方案的制定提供一些依据。  相似文献   

6.
目的:总结痛泻要方加味治疗肠道易激综合征的临床疗效.方法:42例肠道易激综合征患者均为我院门诊病例;临床辨证均属肝郁脾虚型,采用痛泻要方为主方,并随症加减,服药1~3个疗程,并随访半年以上,以观察服药后的疗效.结果:42例患者经服用痛泻要方加味治疗后,其中显效病例为23例(54.7%),有效15例(35.7%),无效4例(9.5%),总有效率为90.5%.结论:肠道易激综合征患者经服用痛泻要方加味治疗后,能有效地控制临床症状,提高本病的治愈率.  相似文献   

7.
目的:总结痛泻要方加味治疗肠道易激综合征的临床疗效.方法:42例肠道易激综合征患者均为我院门诊病例;临床辨证均属肝郁脾虚型,采用痛泻要方为主方,并随症加减,服药1~3个疗程,并随访半年以上,以观察服药后的疗效.结果:42例患者经服用痛泻要方加味治疗后,其中显效病例为23例(54.7%),有效15例(35.7%),无效4例(9.5%),总有效率为90.5%.结论:肠道易激综合征患者经服用病泻要方加味治疗后,能有效地控制临床症状,提高本病的治愈率.  相似文献   

8.
目的:探讨生物反馈疗法对肠易激综合征(irritable bowel syndrome, IBS)的疗效.方法:将53例IBS患者随机分为试验组和对照组,两组均给予常规药物治疗,试验组在此基础上给予为期1个月的肌电生物反馈治疗.治疗前后分别对两组患者进行抑郁自评量表(Self-rating depression scale, SDS)、焦虑自评量表(self-rating anxiety scale, SAS)、胃肠道症状评定量表(gastrointestinal symptoms rating scale,GSRS)评分及内脏痛阈值测定.结果:治疗1个月后,与对照组相比,试验组患者的各项评分明显降低(P<0.05),内脏痛阈值明显升高(P<0.05).结论:生物反馈疗法治疗IBS可明显改善患者症状及心理状况.  相似文献   

9.
5-羟色胺及其与抑郁症和肠易激综合征的关系   总被引:1,自引:0,他引:1  
5-羟色胺是机体内一种重要的神经递质和自体活性物质。本文介绍了该物质在机体内的合成过程和生理功能,并概述了其与抑郁症和肠易激综合征的关系。  相似文献   

10.
[目的]:观察不同剂量的辛伐他汀对2型糖尿病的高血脂治疗疗效.[方法]:将104例根据临床症状、血糖及存在不同程度脂代谢紊乱患者随机分成辛伐他汀20 mg、40 mg及80 mg治疗组,于治疗24周复查血脂.[结果]:辛伐他汀常规剂量和强化治疗均能降低总胆固醇和低密度胆固醇作用,强化治疗效果更好.[结论]:辛伐他汀强化治疗剂量明显优于常用处方剂量.  相似文献   

11.
Objective: To assess the diagnostic efficiency of OMOM capsule endoscopy (CE) in a group of patients with different indications. Methods: Data from 89 consecutive patients (49 males, 40 females) with suspected small bowel disease who under- went OMOM CE (Jinshan Science and Technology Company, Chongqing, China) examination were obtained by retrospective review. The patients’ indications of the disease consisted of the following: obscure gastrointestinal bleeding (OGIB), abdominal pain or diarrhea, partial i...  相似文献   

12.
INTRODUCTION Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder. The typical symptoms are abdominal pain, flatulence, and irregular bowel movement. Prevalence rates are re- ported to be as high as 30% in the general population (Drossman et al., 1982), corresponding to about 25%~50% of all patients who need gastroenterolo- gist’s help (Everhart and Renault, 1991). Despite this high prevalence, the cause of IBS is unknown. Many factors are likely to …  相似文献   

13.
The pathophysiology of irritable bowel syndrome (IBS) is complex and not fully understood, so the aim of this study was to evaluate whether visceral and somatic hypersensitivity, autonomic cardiovascular dysfunction, and low-grade inflammation of the gut wall are associated with diarrhea-predominant IBS (D-IBS). Sixty-two patients with D-IBS and 20 control subjects participated in the study. Using the ascending method of limits (AML) protocol, we demonstrated that D-IBS patients had significantly lower sensory thresholds compared with healthy controls (P<0.001). Using diverse methods, especially the ischemic sensitivity test, for the first time in China, we confirmed that D-IBS patients have somatic hypersensitivity. They had a significantly higher systolic blood pressure and heart rate after a cold stimulus, indicative of autonomic cardiovascular dysfunction. Compared with the control group, D-IBS patients had a significantly higher level of calprotectin (P<0.001). We also found significant correlations between visceral and somatic hypersensitivity, visceral hypersensitivity and autonomic cardiovascular dysfunction, and somatic hypersensitivity and autonomic cardiovascular dysfunction. Our findings may provide valuable suggestions for the treatment of D-IBS.  相似文献   

14.
The prevalence of irritable bowel syndrome (IBS) and associated factors, especially psychological and lifestyle factors, in nurses in China have not been investigated previously. The aims of this study were to assess the prevalence of IBS in nurses, to evaluate whether factors, such as psychological disorders, are associated with IBS, and to determine whether psychological disorders can influence the severity of symptoms of IBS and quality of life (QOL). A cross-sectional study was conducted for Chinese nurses from November 2012 to February 2013. Participants were asked to complete questionnaires. The prevalence of IBS was 17.4%. The revised symptom checklist 90 (SCL-90-R) scores were significantly higher for nurses with IBS than for those without IBS (P<0.001), and no difference in scores between IBS subtypes was found (F=1.893, P=0.142). The scores of QOL for nurses with and without IBS were 77.18±21.93 and 88.44±11.89 (P<0.001), respectively. Psychological disorders did not show statistically significant correlations with severity of symptoms of IBS or QOL. Alcohol consumption, low level of exercise, and psychological disorders were risk factors for IBS. In summary, nurses in China show a high prevalence of IBS. Psychological disorders and some related lifestyle factors are probably responsible for the development of IBS in nurses.  相似文献   

15.
OBJECTIVE: During the past 10 years, researchers have documented how trauma--especially severe trauma--can alter the functioning of the brain. In some cases, these alterations create a state of chronic hyperarousal. The present review serves as an introduction to this research. FINDINGS: Persons who have experienced traumatic events are often "primed" to over-react to subsequent stressors, making them more vulnerable to these events. CONCLUSION: Chronic hyperarousal underlies three common and often co-occurring sequelae of childhood abuse: post-traumatic stress disorder (PTSD), depression, and irritable bowel syndrome. Knowledge of these physiological correlates can affect treatment decisions as well as our theories about the mechanisms underlying the development of symptoms.  相似文献   

16.
以早籼稻“嘉育948”为材料,研究了 Al~(3+)、ABA、Ca~(2+)对水稻生长的影响及三者之间的相互关系.结果表明,Al~(3+)能抑制水稻种子的萌发和幼苗的生长发育.且这种毒害效应随Al~(3+)浓度的增加而增强.外源 ABA 和 Ca~(2+) 能提高水稻幼苗在铝胁迫条件下的抗逆性,极低浓度的ABA和适量的Ca~(2+)还能完全逆转 AP~(3+)对植株生长的抑制作用.  相似文献   

17.
Extensive intestine resection may result in short bowel syndrome (SBS) which is difficult of manage. This study reports a rare SBS case in a 6-year-old boy following resection of total jujunoileum and right colon. Our experience in 4-years follow-up and literature reports on SBS is discussed. The purpose of this study was also to evaluate the nutritional absorptive capacity and intestinal adaptation. In the 15th postoperative month, barium x-ray study showed a significantly extended and enlarged duodenum and colon. The intestinal transit time was prolonged to 22 hours. The absorption rate of palmic acid, glycine and D-xylose had increased from 57%, 50% and 4% respectively in the 15th postoperative month, to 75%, 65% and 6% in the 2nd postoperative year. His absorptive capacity allowed him normal oral feeding and normal school life. Our data confirmed the reports of the colon as an energy-salvage organ, and suggested that it may have some capacity to absorb long-chain fatty acids and amino acids.  相似文献   

18.
氩离子凝固术治疗消化道息肉疗效观察   总被引:2,自引:0,他引:2  
[目的]探讨氩离子凝固术对消化道息肉的治疗作用.[方法]采用德国ERBE公司生产的APC300型内镜专用氩气刀对消化道息肉进行氩离子凝固术.[结果]121例息肉患者,其中食道息肉15例,胃息肉14例,十二指肠息肉10例,结肠息肉62例,直肠息肉15例,全部一次治愈,少数患者出现腹胀、腹部隐痛,无出血、穿孔等并发症出现.[结论]氩离子凝固术治疗消化道息肉疗效确切、安全.  相似文献   

19.
[目的]观察绿脓杆菌菌苗治疗复发性口腔溃疡的疗效.[方法]62例复发性口腔溃疡患者被分为菌苗组(32例)和胸腺肽对照组(30例),并对二组疗效进行比较.[结果]菌苗组的总有效率(93.75%)明显高于胸腺肽对照组(73.33%).二者有显著性差异(P<0.05).[结论]菌苗的良好效果是由于其免疫调节作用和微量元素、维生素的调节作用.  相似文献   

20.

Objective  

Inflammatory bowel diseases (IBDs) are idiopathic, chronic, and inflammatory intestinal disorders. The two main types, ulcerative colitis (UC) and Crohn’s disease (CD), sometimes mimic each other and are not readily distinguishable. The purpose of this study was to present a series of hospitalized cases, which could not initially be classified as a subtype of IBD, and to try to note roles of the terms indeterminate colitis (IC) and inflammatory bowel disease unclassified (IBDU) when such a dilemma arises.  相似文献   

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