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1.
Shibba Takkar Chhabra Shivani Mehta Sandeep Chhabra Manikant Singla Naved Aslam Bishav Mohan Gurpreet Singh Wander 《Indian journal of clinical biochemistry : IJCB》2018,33(2):235-238
Torsades de pointes with prolonged QTc interval is a form of ventricular tachycardia. Many predisposing factors have been identified and hypocalcemia is among the rare ones. Our case illustrates that though rare, hypocalcemia might manifest as torsades de pointes with prolongation of QTc interval. Early diagnosis and management of dyselectrolytemia can prevent these patients from catastrophic torsades de pointes. 相似文献
2.
Chhabra Meenakshi Ribeiro Marcelo Afonso Rossier Jérôme 《International Journal for Educational and Vocational Guidance》2022,22(3):577-579
International Journal for Educational and Vocational Guidance - 相似文献
3.
The context of the study presented in this paper is a sixth-semester undergraduate course on “Relational database management system” that was held in session 2009–2010. The course is part of the bachelor’s degree curriculum of Computer Science and Engineering branch at Punjab Technical University, Punjab, India. It consists of a lecture course and a concurrent lab course. The common approach has been to divide the course into lectures, tutorials, and practicals. To conduct practical sessions, lab plan is prepared beforehand by the faculty. The course duration is 14–16 weeks. Here the lab course was conducted in a blended learning mode, starting with syllabus related tasks, then subject specific projects, and presenting team project results. Problem based learning (PBL) and Blogging have been introduced for practical sessions. This paper describes this novel approach in which problems are designed to cover the syllabus topics, and blogging is used to bridge the communication gap. A significant difference was seen between performance and attitude of the treatment group (PBL with blogging) and control group (only PBL) for Lab sessions. Additionally teamwork and communication skills were also significantly improved in the case of PBL with blogging class. 相似文献
4.
Kalpana Luthra Suman Vasisht Shivani Chhabra K. R. Raju D. P. Agarwal S. C. Manchanda L. M. Srivastava 《Indian journal of clinical biochemistry : IJCB》1998,13(1):12-19
Lipoprotein Lp(a) excess has been identified as a powerful predictor of premature atherosclerotic vascular diseases. To evaluate
this in a North-Indian population, 130 CAD patients and 130 controls were analyzed. The size of the apo(a) phenotypic isoforms
was inversely proportional to Lp(a) concentrations. The mean concentration of Lp(a) in the CAD patients was 42±34 mg/dl whereas
in the normal subjects it was much lower, 27±27 mg/dl. 157 subjects out of the total 260 subjects showed plasma levels of
>20mg/dl. The frequency of high Lp(a) levels was much higher in patients(73%) than controls (43%). These data suggest (1)
that there is heterogeneity of the Lp(a) polymorphism, (2) Higher Lp(a) levels were found in patients than in the controls,
(3) Patients showed 1.5 fold increase in Lp(a) levels as compared to the controls. We conclude that low molecular weight apo(a)
isoforms are significantly associated with increased risk of CAD in the North-Indian population. 相似文献
5.
Narotam Sharma Veena Sharma Tariq Masood Satish Chandra Nautiyal Shivani Sailwal Rajesh K. Singh Rajeev K. Kushwaha R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(2):189-192
Ankylosing spondylitis is a chronic inflammatory disease that has been linked to the human leukocyte antigen class I allele HLA-B27. More than 90 % of patients with ankylosing spondylitis possess the HLA-B27 allele, but only 1 % of people with HLA-B27 develop the disease. Ankylosing spondylitis predominately affects young males. The present study was planned to find out the involvement of HLA-B27 specific allele in relation to age and sex in symptomatic suspected patients of ankylosing spondylitis using conventional PCR technology. Forty symptomatic patients of ankylosing spondylitis were included in the present study. SSP–PCR technique was used to detect the HLA-B27 specific allele. This study showed (out of 40 symptomatic suspected cases of ankylosing spondylitis only 12 patients were detected positive with HLA-B27 allele, while remaining 28 were negative) that the positivity rate for ankylosing spondylitis with HLA-B27 allele is low. Furthermore, it was observed that the males above 50 years are more prone to develop AS with HLA-B27 specific allele. It could be concluded that the conventional PCR technology is a rapid, sensitive, and confirmatory method for the diagnosis of ankylosing spondylitis. 相似文献
6.
A. P. S. Narang H. S. Bains Shivani Kansal D. Singh 《Indian journal of clinical biochemistry : IJCB》2006,21(1):89-94
Human milk samples were collected from 86 mothers induced in the study on days 3, 7, 14 and 28 of lactation. The mothers were
divided into three groups on the basis of gestation viz. group 1: 37–41 weeks (n=41), group II: 33–36 (n=23) and group III:
<33 weeks gestation (n=22). All the samples were analysed for the estimation of fat, lactose and protein. The results obtained
from the investigations were statistically analysed. The analysis of the results revealed a lower amount of fat and lactose
in preterm milk as compared to term milk (p<0.01). These were found to increase in amount with increasing postnatal age (p<0.05).
The protein levels were observed to be significantly higher in preterm than term milk (p<0.01). These were observed to decrease
significantly with increase in postnatal age (p<0.01). 相似文献
7.
Pratima Tripathi M. K. Misra Shivani Pandey 《Indian journal of clinical biochemistry : IJCB》2012,27(3):296-299
Oxidative stress conditions associated with atherosclerosis leads to oxidative modification of low-density lipoprotein (LDL). The body’s capabilities to inhibit LDL oxidation and to remove or neutralize the atherogenic oxidized LDL (ox-LDL) are limited. When the LDL cholesterol level increases in the blood, it leads to dangerous consequences like atherosclerosis, leading to myocardial infarction. The major effect of an antioxidant in the LDL environment is to prevent the formation of ox-LDL (during atherogenesis. Strategies to reduce LDL oxidation and prevent atherogenesis can involve the enrichment of arterial cells with potent antioxidants that can prevent oxidative damage to the arterial wall. The objective of this study is to evaluate the effect of l-arginine on serum lipid and cholesterol levels in the patients of acute myocardial infarction (AMI). The study consisted of 70 AMI patients and 60 healthy individuals (serving as control) age 55–65 years. Serum levels of total cholesterol, high density lipoprotein (HDL), LDL and Triglycerides were determined on day 1 and day 15 of l-arginine administration (oral dose 3 g/day). The total cholesterol/HDL and the LDL/HDL ratio were calculated and compared. As per the observations, l-arginine administration was found to improve the lipid profile of the subjects. Hence it could be used as an adjuvant therapy for AMI and as a preventive measure for the onset of the disease in the healthy elderly also. 相似文献
8.
S. Chhabra D. P. Agarwal S. Vasisht K. Luthra R. Narang S. C. Manchanda L. M. Srivastava N. Das 《Indian journal of clinical biochemistry : IJCB》2003,18(2):34-38
Several studies including a small case-control (hypertriglyceridemic/normotriglyceridemic individuals) study by us revealed
close association between rare S2 allele ofAPOC3 Sstl polymorphism and hypertriglyceridemia. With the understanding that Asian Indians are highly vulnerable to the adverse
effects of hypertriglyceridemia, we extended the investigation and studied the frequency distribution of this polymorphism
in 216 healthy volunteers from Northern plains of India. We found that more than 50% of the study population had one or two
S2 allele. This may suggest that a larger fraction of this population is genetically predisposed to hypertriglyceridemia. 相似文献
9.
In this article, we describe our experiences of conducting a series of workshops titled ‘It’s a MATERIALS world!’ to popularize Materials Science among school children in India. Some of the hands-on activities that can be performed with easily available ingredients/equipment in a classroom are described for the benefit of educators. 相似文献
10.
Arun Kumar Singh Sunita Tiwari Abhishek Gupta Kamla Kant Shukla Kumar Gaurav Chhabra Achileshwar Pandey Aditya Bhushan Pant 《Indian journal of clinical biochemistry : IJCB》2015,30(3):255-262
Metabolic syndrome (MetS) is a cluster of interrelated common clinical disorders. The role of resistin in insulin sensitivity and MetS is controversial till date. So, the aim of the present study was to investigate the relationship of plasma resistin levels with markers of the MetS in Indian subjects. In a case control study, total 528 subjects were selected for the study. 265 (194 male and 71 female) were cases (with MetS) and 263 (164 male and 99 female) were controls (without MetS). Required anthropometric measurements and calculations were carried out accordingly. All the Biochemical estimations were carried out according to standard protocol. Resistin level was measured by the standard protocol (By ELISA i.e. enzyme linked immunosorbent assay) as illustrated in the kit. Insulin level was also measured by the standard protocol as illustrated in the kit and insulin resistance was calculated by the standard procedures. Plasma resistin levels were significantly higher in cases compared with controls (male = 13.05 ± 4.31 vs. 7.04 ± 2.09 ng/ml; p ≤ 0.001 and female = 13.53 ± 4.14 vs. 7.42 ± 2.30 ng/ml; p ≤ 0.001). Plasma resistin levels were well correlated with waist circumference, glucose, triglycerides, waist/hip ratio, systolic and diastolic blood pressure, high density lipoprotein, total cholesterol, serum low density lipoprotein, serum very low density lipoprotein, insulin and insulin resistance. Plasma resistin levels were elevated in presence of the MetS and were associated with increased metabolic risk factors. 相似文献