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21.
The circadian periodicity of plasma lipid peroxide levels and activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were studied in 50 clinically, bacteriologically and radiologically proven fresh cases of pulmonary tuberculosis (age: 21–45 years) and 60 age-matched healthy volunteers with diurnal activity from 06∶00 to about 22∶00 and nocturnal rest. A marked circadian variation in plasma lipid peroxide level was recorded in healthy subjects and pulmonary tuberculosis patients with significant amplitude and acrophase around 16∶21 and 17∶12 respectively. The acrophase tended to be delayed in tuberculosis patients. Furthermore, a statistically significant circadian rhythm was found in SOD, CAT and GPx activities in normal volunteers and pulmonary tuberculopsis patients. SOD and CAT enzyme activity was noted to be maximum at 06∶00 and minimum at 00∶00 in tuberculosis patients. The circadian acrophase for GPx activity was recorded at 16∶15 in normals and around 22∶45 in patients. Moreover, the activity was found to be decreased at all sampling hours during 24-hours sleep-awake period in patients in comparison to healthy counterparts. The MESOR and circadian amplitude also decreased markedly. The decreased activity of measured antioxidant enzymes in pulmonary tuberculosis patients could probably be associated with oxidative stress and/or decreased anti-oxidant defensive mechanism in such patients.  相似文献   
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A suitable simple optical cryostat for optical, magneto-optical, electrical and thermo-electrical measurements was designed. It is suitable for use in a magnetic pool gap as narrow as less than 1 cm. Throughout a long period of time, the heat diffusion process of the cryostat can be easily operated at slow increase in sample temperature in a range 1.25 K/min at 200 K that will be reduced gradually to 0.66 K at room temperature. Liquid nitrogen was used to cool down the temperature. During the operation, the change in the measured energy gap of a semiconductor sample and other physical parameters resulting from the change of temperature can be corrected through the temperature coefficient of that parameter at the corresponding temperature. The cryostat was successfully used for all experiments mentioned above to measure the properties of a single crystal of GaP (Gallium Phosphate) semiconductor.  相似文献   
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Systems designed to ensure that teaching and student learning are of a suitable quality are a feature of universities globally. Quality assurance systems are central to attempts to internationalise higher education, motivated in part by a concern for greater global equality. Yet, if such systems incorporate comparisons, the tendency is to reflect and reproduce inequalities in higher education. Highlighting the European context, we argue that, if higher education is to play a part in tackling social inequalities, we must seek alternative methods to explore pedagogic quality in institutional settings. The sociologist Basil Bernstein’s concepts of classification and framing provide an illustration of the potential of sociologically informed, qualitative approaches for exploring and improving higher education pedagogy and also for addressing social justice issues: these two concepts are used to analyse documentation about undergraduate sociology in two universities that have quite different reputations within the English and Northern Irish higher education system.  相似文献   
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This article is a theoretical and empirical study of the ways in which different South Asian groups, Bangladeshi, Indian, and Pakistani, achieve entry into the selective education system, taking into consideration the factors of social class, ethnicity and culture. In‐depth interviews with 42 South Asian school pupils from three single‐sex selective schools (one independent and two grammar), 47 South Asian school pupils from three secondary modern schools, and 25 South Asian parents are used to interpret perceptions, attitudes towards, and experiences of selective school entry. It is found that that certain working‐class South Asian parents possess strong middle‐class attitudes towards selective education, irrespective of their ability to facilitate it as a function of their financial, cultural, or social capital. Middle‐class South Asians were not only highly motivated but also possessed the economic, social and cultural capital to ensure successful selective school entry. In general, social class status was the strongest factor in the likelihood of gaining entry into selective schools. This research contributes to the literature on selective education as well as on the intricacies of the British South Asian educational experience.  相似文献   
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Microfluidic technology provides precise, controlled-environment, cost-effective, compact, integrated, and high-throughput microsystems that are promising substitutes for conventional biological laboratory methods. In recent years, microfluidic cell culture devices have been used for applications such as tissue engineering, diagnostics, drug screening, immunology, cancer studies, stem cell proliferation and differentiation, and neurite guidance. Microfluidic technology allows dynamic cell culture in microperfusion systems to deliver continuous nutrient supplies for long term cell culture. It offers many opportunities to mimic the cell-cell and cell-extracellular matrix interactions of tissues by creating gradient concentrations of biochemical signals such as growth factors, chemokines, and hormones. Other applications of cell cultivation in microfluidic systems include high resolution cell patterning on a modified substrate with adhesive patterns and the reconstruction of complicated tissue architectures. In this review, recent advances in microfluidic platforms for cell culturing and proliferation, for both simple monolayer (2D) cell seeding processes and 3D configurations as accurate models of in vivo conditions, are examined.  相似文献   
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This article reports some of the results of interviews with 120 Israeli Druze, 60 middle-aged adults and 60 young adults, regarding values, views of the Druze community, and personal identity. All participants expressed commitment to and love for traditional Druze values of familial respect, respect for others, modesty in dress and behavior, and commitment to Druze beliefs about one, all-powerful God and the reincarnation of Druze souls within the Druze community. Because the Druze religion is secret, open for study only to those Druze who live according to the letter of the religious law, most Druze today are not religious, defining themselves as traditional. Education in Druze values, mostly in the family, is the extent of their religious education. Most participants expressed a need for there to be some religious concessions made by the sheiks who set and enforce religious policy, in order that more people may pursue higher education and work outside the village and also study the inner secrets of their religion. Without this the Druze religion may be in danger. Connection is drawn between the Druze and other traditional religious societies.  相似文献   
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The Specialised Vocational Training Institutions (IMPro) in France have recently entered into a difficult, but important period of time. During the past few years, IMPro have faced increasing demand from the public and government to provide quality service to adolescents with intellectual disabilities. IMPro have been also faced with the challenge of being accountable for the low employment rate of adolescents with intellectual disability and their failure to obtain and/or maintain jobs due to lack of technical and social skills. The purpose of the present work was to respond to the increasing and urgent needs in IMPro by designing and developing a training system to enhance organisational productivity, increase employment rate, and eliminate the problems faced by workers with intellectual disabilities. This article describes the process of organisational changes in IMPro using systems thinking. It discusses the model, methods, tools, and techniques used in designing, developing, implementing, and evaluating the new system of training in IMPro in an attempt to improve the quality, effectiveness, and efficiency of their training programs.  相似文献   
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Quality of diagnostic data depends on accurate coding. The purpose of this study was to assess the accuracy of principal diagnosis coding and its effective factors. To achieve this aim, three hundred and seventy medical records were randomly selected and recoded blindly (as gold standard). The effects of possible factors on accuracy of coding which was gathered through observation method were analyzed by Chi-square (χ2), Fisher exact test, odds ratio (OR), and confidence interval 95% for OR.  相似文献   
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