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991.
Andrew W.M. Fry 《Child abuse & neglect》1981,5(2):159-165
During the course of the Special Unit's operation it became apparent that in many cases there was a demonstrable need for assessment; for a period of involvement with the family by one worker who could not only explore the background information, from parents and agencies alike, but also engage the whole family in an interventive schedule which explores their positive development by the use of a number of treatment modalities, the effectiveness of which could be evaluated in operation. Time-tabled case conferences on a weekly basis with a standing membership at the core reflecting the membership of the policy-making Area Review Committee, supplemented by other workers also involved in each case, provide the regular and consistent forum from which assessment cases are referred and for which assessment reports are prepared. The assessment process is the beginning of a long-term interventive schedule in which the clients and workers both participate. The system is, in essence and practise, a simple one but its effects have been felt not only in terms of ongoing casework with families but also at the level of policy-making in reappraisal of our traditional agency attitudes to child abuse. 相似文献
992.
993.
994.
Nicholas D Williams P Smith A Longbottom P 《Health information and libraries journal》2005,22(1):35-43
AIMS/OBJECTIVES: To undertake an information-needs analysis of operating theatre staff in order to inform the development of a specialist library of the National Electronic Library of Health (NeLH). SETTING: Three hospitals in an NHS Trust in a rural county in the north of England. METHODS: In-depth interviews, during which staff were questioned in regard to their job roles and information needs, information-seeking behaviour, access to computers, use and perceptions of the NeLH, and what they would like from a specialist library. RESULTS: Information needs were found to concern direct care, professional and academic development, medical devices knowledge and administration. Currency and speed of delivery were the key information requirements. Poor communication appeared to be a major problem for many staff and inhibited efficient information exchange. When using the Web, both clinical and non-clinical staff searched in a similar fashion to health consumers generally, despite their need for highly specialist information. Most respondents reacted warmly to the idea of the proposed National Electronic Library for Theatre Staff (NeLTS) and made several practical suggestions for suitable material. However, access was problematic for nurses and might prove to be an obstacle to take-up of the Specialist Library. CONCLUSIONS: Communication difficulties, the fragmentation of data in the field and the consequent difficulties of finding information point to the need for an NeLTS. However, for this library to embrace and succeed with all the various groups that constitute the operating theatre staff, issues of access and digital literacy need to be addressed. 相似文献
995.
996.
Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted
with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion,
the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and
an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior
and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive
responses to the same stimulus. 相似文献
997.
998.
Hogan AJ 《Endeavour》2012,36(2):77-84
What does it look like to be the carrier of a genetic disease? Carrier status may be determined through the visual analysis of both genotypic and phenotypic evidence. Over the past 70 years, clinical geneticists have depended upon multiple strategies for identifying disease carriers within a family. This has included pedigree analysis, which was based upon clinical observations of individual family members and, in recent decades, cytogenetic and molecular methods. Newer techniques have offered novel opportunities to actually see the suspected etiological markers of certain genetic diseases, such as Fragile X syndrome. The visualization of these markers has both clarified and confused previously observed inheritance patterns, in some cases leading to the development of newly distinct diagnostic categories. As a result, what it means to be affected by, or the carrier of, a genetic disease has continuously evolved. 相似文献
999.
Kavita Shalia Sudha Savant Vijaya A. Haldankar Tulip Nandu Poonam Pawar Siddhi Divekar V. K. Shah Purvi Bhatt 《Indian journal of clinical biochemistry : IJCB》2012,27(1):74-82
To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism
of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32
patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number
of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried
out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and
their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation
with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low
risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event. 相似文献
1000.
Meera S. Ghadge Purva P. Naik Bijaynath P. Tiwari Ruprekha M. Hegde Tanaji J. Matale 《Indian journal of clinical biochemistry : IJCB》2012,27(1):97-99
Breast cancer is one of the most frequent malignancies in the world. Available staging procedures to detect breast cancer
are bone scan, chest X-ray, liver ultrasonography, computerized tomography, estimation of tumor markers like carbohydrate
antigen (CA15-3) and carcino embryonic antigen. These procedures are expensive and may not be required in all cases. Out of
70 patients studied, 55 had normal CA15-3 and 15 had elevated levels of Ca15-3. Eight (14.5%) of the 55 patients with normal
CA15-3 had abnormal bone scan. Fifteen patients had CA15-3 levels above the normal range and among these 9 (60%) had abnormal
bone scan. While prime facie it would appear that a high level of CA15-3 correlate with abnormal bone scan, it is also true
that the numbers are small at present and conclusions about the validity of CA15-3 as marker of bone metastasis may be premature. 相似文献