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41.
Kaushik Kar Anindya Dasgupta M. Vijaya Bhaskar K. Sudhakar 《Indian journal of clinical biochemistry : IJCB》2014,29(2):232-237
Decompensation followed by death is the most serious outcome in patients suffering from cirrhosis of the liver. Alteration of trace elements may play a vital role in the process of decompensation. To examine the change in status of trace elements during the decompensation process, we analysed the zinc, copper, iron, magnesium, bilirubin and albumin levels in the serum of compensated (n = 34) and decompensated (n = 31) liver cirrhosis patients and compared them with healthy control group (n = 36) by post hoc ANOVA. We observed significant alteration in the selected micronutrients in the diseased group relative to healthy controls (P < 0.05). Moreover, mean serum zinc and iron levels were significantly lower with a higher level of serum copper in decompensated cirrhosis group than in compensated group (P < 0.05). However, no significant decrease of serum magnesium was found between the two diseased groups. Our findings imply that the trace elements like zinc, copper and iron might exert important contributory roles in decompensation process in liver cirrhosis and hence, may be utilized as important biomarkers for these patients. Furthermore, we propose that replacements of those micronutrients at an early stage can delay or prevent the severe outcomes like hepatic encephalopathy, gastrointestinal bleeding, severe jaundice or ascites in these patients. 相似文献
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This paper examines the perceptions of three Somali mothers on science, science topics taught in urban US schools and the challenges that they encountered in dealing with science and their own social and cultural practices. The article focuses on Somali mothers, who were highly interested in articulating how science and science professions could be a path to both the personal and community successes and how science could positively affect Somali girls in the areas of women’s health. As an exploratory case study research, we used grounded theory approach to understand Somali mothers’ perceptions of science. We interviewed the mothers over a year and analyzed data as an iterative and systematic process. The findings of the study show that the Somali mothers perceived science from everyday usefulness points of view rather than science knowledge alone, thus home-science connections were critical to them as Somali mothers. They perceived science as an empowering tool for girls so they could make important decisions about women’s reproductive health issues. A broader implication of this study could be for urban science teachers and educators to modify their science instructional and curricular decisions so science learning is connected to Somali students’ culture and empowers girls. 相似文献
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Karan Rangarajan Khalil Begg Bhaskar Somani 《The American journal of distance education》2019,33(2):142-150
There has been considerable growth in the uptake of digital clinical education (DCE) over the last few years. This growth has coincided with similar growth in social media platforms available to both educators and learners. In this article, we describe a novel, innovative video-based medical education project using YouTube for teaching, training, and learning. We created a series of short ‘System based’ clinical scenario videos and uploaded it to YouTube. Using the analytics function provided by Google and YouTube, end-user data including viewer engagement, uptake, and comments were then analyzed. To date, the channel has garnered more than 5.5 million views over five years between July 2012-July 2017.
With the increase in the use of video-based learning and the popularity of social media platforms, the uptake of DCE is set to increase. YouTube offers a novel approach to streaming medical education for training purposes. A quality assessed, structured and sustainable educational online platform is likely to meet the future requirements of a new generation of learners. 相似文献
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Cultural Studies of Science Education - In this conceptual paper, we argue that social justice, morality, and healing must be at the core of an equity agenda for science education. When we view... 相似文献
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Pazhanivel Mohan Varun Sundar Emmanuel Bhaskar Syluvai Anthony 《Indian journal of clinical biochemistry : IJCB》2017,32(3):337-342
Alanine aminotransferase (ALT) is the most common and cost effective screening test for asymptomatic liver disease. There is paucity of data on normal ALT among healthy individuals in India. An observational cross sectional study was conducted from January to July 2013 to estimate the upper limit of normal for ALT in healthy south Indian population. Adults undergoing voluntary or pre-employment health screening were included. Those with current and past alcoholism or smoking, acute illness or hospitalization during preceding 12 months, non-steroidal anti-inflammatory or over the counter medication use within a month, current or past intake of herbal medications, any chronic medical illness, abnormal body mass index (BMI), fatty liver in ultrasound, abnormality in haemoglobin, platelet count, blood sugar, creatinine, lipid profile and thyroid function test and positive serology (Hepatitis B, C or HIV) were excluded. A total of 2600 subjects were screened. 344 were included for analysis. Mean age was 35 years in men and 34.83 years in women, with a mean BMI of 22.2 kg/m2 in men and 21.8 kg/m2 in women. The mean ALT in men and women were 21.87 ± 2.9 (97.5th percentile 28 U/L) and 19.35 ± 3.3 (97.5th percentile 24 U/L) respectively. In conclusion, mean and upper limit of ALT (97.5th percentile) in south Indian men was 21.87 and 28 IU/L and women were 19.35 and 24 IU/L respectively. There is a need to re-consider ALT levels in our population for better detection of individuals at risk for liver disease. 相似文献
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K. S. S. Saibaba M. Vijaya Bhaskar P. V. L. N. Srinivasa Rao G. V. Ramana K. V. Dakshinamurty 《Indian journal of clinical biochemistry : IJCB》1998,13(2):55-62
Analyses of body fluids in clinical chemistry laboratory are subject to a number of interferences that affect the analytical
accuracy. The interferents arise from exogenous sources like drugs and additives as well as such endogenous sources like lipemia,
hemolysis and icteria. Our studies demonstrate matrix interference in the form of analytical blas between serum and aqueous
matrix calibrators. The clinical chemist should constantly be aware of this factor. Correction of interferences is recommended
as an integral part of the quality assurance program. 相似文献
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Bhaskar S Veena Sharmila Upadhya Satish Kumar Adiga Kumar N Pratap 《Indian journal of clinical biochemistry : IJCB》2008,23(2):186-190
The objective of the study was to estimate the serum concentrations of oxidative stress markers-lipid hydroperoxide (MDA-Malondialdehyde),
lactate dehydrogenase (LDH), nitrite; and ferric reducing antioxidant power (FRAP) — a measure of total antioxidant capacity
in serum. Serum nitrite levels were high in fertile women than in infertile women (p<0.001), whereas MDA was high in infertile
women than in fertile group (p<0.018). On classifying the entire group of women with infertility based on the etiology, serum
MDA and LDH levels were higher in women with infertility due to unexplained factor than in women with other causes contributing
to infertility compared to controls (p<0.001, p<0.02). A positive correlation among serum prolactin and nitrite suggested
that hyperprolactinemia could contribute to infertility by inducing oxidative damage. Serum FRAP levels showed no significant
difference in the groups studied. Lipid peroxidation was high in women with unexplained infertility which may be due to hyperprolactinemia. 相似文献
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Catherine Milne Laurie Rubel Alberto J. Rodriguez Christopher Emdin Maria Rivera Maulucci Donyagay Locke Edna Tan Neil Clairmont Bhaskar Upadhyay 《Cultural Studies of Science Education》2009,4(2):399-407
This metalogue addresses the ways Sreyashi Jhumki Basu mediated our practices in science education and life. We focus on Basu’s
uses of critical science agency, democratic science classrooms, and critical feminist ethnography to transform the possibilities
for all participants in her research and educational practices. We also examine her use of cases and pedagogical strategies
to support youth set practice goals based on conceptions of self and preferred learning trajectories. These strategies allow
youth to develop power through the use of disciplinary knowledge and modes of inquiry to support their understanding of themselves
as powerful, able to change their position in the world, and make the world more socially just. This (Key Contributors) article
acknowledges a life cut short through disease, reflects our personal loss of a friend and colleague, and expresses determination
to ensure that her contributions to science education are sustained and continued.
相似文献
Catherine MilneEmail: Email: |