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排序方式: 共有117条查询结果,搜索用时 15 毫秒
61.
Jens Frslev Christensen Michael Holm Olesen andJonas Sorth Kjr 《Research Policy》2005,34(10):1533-1549
This paper addresses how the Open Innovation concept, as recently coined by Henry Chesbrough, can be analyzed from an industrial dynamics perspective. The main proposition of the paper is that the specific modes in which different companies manage Open Innovation in regard to an emerging technology reflect their differential position within the innovation system in question, the nature and stage of maturity of the technological regime, and the particular value proposition pursued by companies. The proposition is analyzed through an in-depth study of the current transformation of sound amplification from linear solid state technology to switched or digital technology within the consumer electronics system of innovation. The analysis especially addresses the complex interplay between technology entrepreneurs and incumbents, and demonstrates that Open Innovation sometimes has to be conducted under conditions of high transaction costs. 相似文献
62.
63.
G Tenenbaum G Fogarty E Stewart N Calcagnini B Kirker G Thorne S Christensen 《Journal of sports sciences》1999,17(3):183-196
The aim of this study was to develop a discomfort questionnaire to elicit the feelings and thoughts of people engaged in running activities. Ten runners who completed a particularly demanding 9-km run were asked to express their feelings and thoughts during the run they had just completed. These responses were recorded and later used as the first pool of items (k = 36). The questionnaire was then given to 171 runners in different distance races throughout the 1995 competitive season. These responses were analysed using exploratory factor analytic techniques and Rasch probabilistic analysis, as well as traditional reliability and validity procedures. The final version of the questionnaire consisted of 32 items divided into eight correlated subscales: proprioceptive symptoms, leg symptoms, respiratory difficulties, disorientation, dryness and heat, task completion thoughts, mental toughness, and head or stomach symptoms. These eight categories can be collapsed into three global categories suggested by researchers of pain: sensory-discriminative, motivational-affective and cognitive-evaluative. Rasch analysis suggested that the motivational-affective and cognitive-evaluative dimensions (i.e. the psychological) are the most experienced (i.e. rated highest). The eight subscales have ecological validity and were found to alter with the demands of different running distances. 相似文献
64.
Thomas J. Kramer Paul Caldarella Lynnette Christensen Ryan H. Shatzer 《Early Childhood Education Journal》2010,37(4):303-309
There has been increasing interest in the promotion of social and emotional learning in schools, and research has shown positive outcomes. However, relatively few studies have been conducted in kindergarten classrooms or considered the feasibility of kindergarten implementation. This study examined the effects of Strong Start on the social and emotional competence of 67 kindergarten students, using a time-series design. Four kindergarten teachers taught the ten Strong Start lessons in their classrooms. Results indicated gains in students’ prosocial behaviors and decreases in internalizing behaviors, as rated by teachers and parents. Implementation integrity and teachers’ ratings of social validity were high, suggesting the program’s feasibility and potential effectiveness in natural classroom settings. Limitations and implications are discussed. 相似文献
65.
Thomas Collins Emily Pyne Martin Christensen Alexander Iles Nicole Pamme Isabel M. Pires 《Biomicrofluidics》2021,15(4)
The majority of cancer deaths are linked to tumor spread, or metastasis, but 3D in vitro metastasis models relevant to the tumor microenvironment (including interstitial fluid flow) remain an area of unmet need. Microfluidics allows us to introduce controlled flow to an in vitro cancer model to better understand the relationship between flow and metastasis. Here, we report new hybrid spheroid-on-chip in vitro models for the impact of interstitial fluid flow on cancer spread. We designed a series of reusable glass microfluidic devices to contain one spheroid in a microwell under continuous perfusion culture. Spheroids derived from established cancer cell lines were perfused with complete media at a flow rate relevant to tumor interstitial fluid flow. Spheroid viability and migratory/invasive capabilities were maintained on-chip when compared to off-chip static conditions. Importantly, using flow conditions modeled in vitro, we are the first to report flow-induced secretion of pro-metastatic factors, in this case cytokines vascular endothelial growth factor and interleukin 6. In summary, we have developed a new, streamlined spheroid-on-chip in vitro model that represents a feasible in vitro alternative to conventional murine in vivo metastasis assays, including complex tumor environmental factors, such as interstitial fluid flow, extracellular matrices, and using 3D models to model nutrient and oxygen gradients. Our device, therefore, constitutes a robust alternative to in vivo early-metastasis models for determination of novel metastasis biomarkers as well as evaluation of therapeutically relevant molecular targets not possible in in vivo murine models. 相似文献
66.
Measuring visitor statistics is a core activity for any website provider. However, the analytical methods have so far been quite limited, difficult, expensive, or cumbersome. Google Analytics (GA) offers a free tool for measuring and analysing visitor statistics. GA was tested on three food composition websites (Denmark, Finland, and Switzerland). All the websites had a considerable number of visitors, which seemed to increase with the maturity of the website. The results also suggested that there were a considerable number of potential unreached users in Denmark and particularly in Switzerland, thus suggesting that promotion be increased and search engines be taken into account more during website design. About 15–20% of users visited the website more than nine times and about 20% spent there more than 10 min on the site. Following traffic from referring websites showed that most of the visitors could not be categorised as food or nutrition professionals. Our experience showed that GA was quite easy to use and gave useful and versatile information that can be used to compare different websites and improve the website design. Finally, we would like to encourage other food composition website providers to utilise either GA or another of the similar tools available. 相似文献
67.
Carrie Ann Christensen 《Teaching Artist Journal》2015,13(1):14-27
“Community engagement” provides a framework for curriculum development in environmental design residencies with elementary students. 相似文献
68.
Gerd Christensen 《International journal of qualitative studies in education》2016,29(6):763-776
The aim of this paper was to demonstrate how genealogy can be used as a method for critical education research. As Foucault emphasized, genealogy is a method for identifying the way in which the individuals are subjectified through discourse. The genealogical analysis in the article defines two mayor tendencies in contemporary Danish pedagogy: individualization and structuralizing. The analyses also show an example of how the two tendencies are intermingled in the Danish law of learning plans in day care institutions. 相似文献
69.
Using Ecological Momentary Assessment, we explored predictors of adolescents' television (TV) multitasking behaviors. We investigated whether demographic characteristics (age, gender, race/ethnicity, and maternal education) predict adolescents' likelihood of multitasking with TV. We also explored whether characteristics of the TV-multitasking moment (affect, TV genre, attention to people, and media multitasking) predict adolescents' likelihood of paying primary versus secondary attention to TV. Demographic characteristics do not predict TV multitasking. In TV-multitasking moments, primary attention to TV was more likely if adolescents experienced negative affect, watched a drama, or attended to people; it was less likely if they used computers or video games. 相似文献
70.