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991.
Mauro Dorato 《Metascience》2016,25(2):173-181
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996.
Apurva Srivastava Neena Srivastava Balraj Mittal 《Indian journal of clinical biochemistry : IJCB》2016,31(4):361-371
Numerous classical genetic studies have proved that genes are contributory factors for obesity. Genes are directly responsible for obesity associated disorders such as Bardet–Biedl and Prader–Willi syndromes. However, both genes as well as environment are associated with obesity in the general population. Genetic epidemiological approaches, particularly genome-wide association studies, have unraveled many genes which play important roles in human obesity. Elucidation of their biological functions can be very useful for understanding pathobiology of obesity. In the near future, further exploration of obesity genetics may help to develop useful diagnostic and predictive tests for obesity treatment. 相似文献
997.
My avatar,my self: Virtual harm and attachment 总被引:1,自引:0,他引:1
Jessica Wolfendale 《Ethics and Information Technology》2007,9(2):111-119
Multi-user online environments involve millions of participants world-wide. In these online communities participants can use
their online personas – avatars – to chat, fight, make friends, have sex, kill monsters and even get married. Unfortunately
participants can also use their avatars to stalk, kill, sexually assault, steal from and torture each other. Despite attempts
to minimise the likelihood of interpersonal virtual harm, programmers cannot remove all possibility of online deviant behaviour.
Participants are often greatly distressed when their avatars are harmed by other participants’ malicious actions, yet there
is a tendency in the literature on this topic to dismiss such distress as evidence of too great an involvement in and identification
with the online character. In this paper I argue that this dismissal of virtual harm is based on a set of false assumptions
about the nature of avatar attachment and its relation to genuine moral harm. I argue that we cannot dismiss avatar attachment
as morally insignificant without being forced to also dismiss other, more acceptable, forms of attachment such as attachment
to possessions, people and cultural objects and communities. Arguments against according moral significance to virtual harm
fail because they do not reflect participants’ and programmers’ experiences and expectations of virtual communities and they
have the unintended consequence of failing to grant significance to attachments that we take for granted, morally speaking.
Avatar attachment is expressive of identity and self-conception and should therefore be accorded the moral significance we
give to real-life attachments that play a similar role.
A shorter version of this paper was presented at the Cyberspace 2005 Conference at Masaryk University, Brno, Czech Republic 相似文献
998.
R. K. Singh A. Bansal S. K. Bansal A. K. Upadhyay V. K. Singh 《Indian journal of clinical biochemistry : IJCB》1992,7(1):61-65
Nychthemeral rhythmicity of urinary copper (Cu) was studied in 40 clinically healthy volunteers and 35 renal stone formers.
A marked diurnal rhythm was noticed in urinary Cu levels in healthy subjects with maximum excretion at 0000 to 0600 hr followed
by a progressive fall during the rest of the period reaching minimum between 1200 to 1800 hr in males and 0600 to 1200 hr
in female volunteers. Similarly, all stone patients exhibited a definite rhythm in urinary Cu with significant amplitude and
acrophases at 2145 hr for males and 2141 hr for female stone formers. However, there was no difference in mean 24-hr Cu excretion
in male and female stone formers, whereas a significant change was observed in case of healthy subjects. Urinary Cu was found
to be significantly increased in renal stone formers in comparison to healthy controls of either sex attributing a significant
role of this overlooked trace mineral in the crystallization and/or activation of either of the process of stone formation
in the renal tubules. 相似文献
999.
Vandana Dixit Ashok V. Kurup A K Gupta O M Kataria G B K S Prasad 《Indian journal of clinical biochemistry : IJCB》1997,12(1):39-43
Lymphatic filariasis caused byWuchereria bancrofti is a major health problem next only to malaria. A study had been conducted to estimate the prevalence of microfilaraemia in a rural endemic community near Raipur. The incidence of microfilaramia in the community was found to be about 14% when studied by night finger prick method. The incidence appears to be more in males as compared to females. The infection rate in vector population i.e.,Culex quinquefasciatus was recorded at a rate of 10%. No relationship could be drawn between the rates of vector and human filarial infections or between the density of vector population and the rate of vector/human infection(s). Prior health education is essential before taking up control and preventive measures in given endemic zone. 相似文献
1000.
Seema Bhargava Meghaa Shanta Bhargava Eishaan Kamta Bhargava LM Srivastava 《Indian journal of clinical biochemistry : IJCB》2016,31(2):148-151
Hyperhomocysteinemia (HHCY) has been demonstrated to affect cochlear microvasculature as well as cochlear epithelial cells directly, with a resultant alteration of the expression of matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloproteinases (TIMPs). Hence, ascertaining the optimum concentration of MMPs and TIMPs in the cochlea could help to inhibit hearing loss due to HHCY by the administration of appropriate MMP inhibitors, Since infections/inflammations as well as ototoxic antibiotics have a similar mechanism of otic pathology, the cochlear damage they cause could also be similarly prevented. 相似文献