Diagnostic efficiency of amylase and type IV collagen in predicting chronic pancreatitis     

Subir Kumar Das  Sowmya Varadhan  L. Dhanya  Sukhes Mukherjee  S. Mohana  V. Balakrishnan  D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2009,24(1):60-64

Chronic pancreatitis, an irreversible inflammatory disease of the pancreas, is associated with the replacement of the destroyed parenchyma by extended development of fibrosis. Despite marked progress in diagnostic tools, no consensus has been reached in diagnosis of chronic pancreatitis. In this study we examined the hematological and biochemical parameters among 40 chronic pancreatitis patients within 18 to 67 yrs. ESR level and ALP activity was elevated in 40% cases. Serum amylase activity increased in 32 patients and it showed significant correlation with ALP (r=0.458, p=0.003), CA-19.9 (r=0.556, p<0.001), and calcium level (r=−0.472, p=0.002). Type IV collagen level in chronic pancreatitis also elevated (164.4 ± 55.5 ng/ml) and showed negative significant correlation with calcium level (r= −0.505, p=0.001). However, no significant correlation was observed between amylase activity and type IV collagen (r=0.289, p= 0.07).  相似文献   

Effect of varying durations of pyramid exposure — an indication towards a possibility of overexposure     

Surekha Bhat  Guruprasad Rao  K. Dilip Murthy  P. Gopalakrishna Bhat 《Indian journal of clinical biochemistry : IJCB》2009,24(4):430-432

Miniature replicas modeled after the Great Pyramid of Giza are believed to concentrate geoelectromagnetic energy within their cavities and hence act as antistressors in humans and animals. Although there are not many reports of adverse effects of ‘overexposure’ in the pyramid, subjects have claimed to feel uneasy after certain duration of staying in the pyramid. The present study was aimed to analyze the effects of prolonged pyramid exposure on plasma cortisol level, markers of oxidative damage and antioxidant defense in erythrocytes of adult female Wistar rats. Rats were divided into three groups, normal controls (NC, n=6) that were maintained under standard laboratory conditions in their home cages, pyramid exposed group-2 (PE-2, n=6) & pyramid exposed group-4 (PE-4, n=6) where the rats were housed under the pyramid for 6 hours/day for 2 weeks and 4 weeks respectively. Plasma cortisol and erythrocyte TBARS levels were significantly lower in both PE-2 and PE-4 rats and erythrocyte GSH levels and GSH-Px activity were significantly higher in them as compared to the NC rats. There was no significant difference in the results for these parameters between the PE-2 and PE-4 rats except for erythrocyte GSH-Px activity which was significantly more in the PE-2 rats than in the PE-4 rats. Although these results don’t confirm any adverse effects of prolonged exposure in pyramids, they indicate a possibility of such adverse effects.  相似文献   

The future of Indian universities: comparative and international perspectives     

Dilip S. Mutum  Bang Nguyen 《Journal of Marketing for HIGHER EDUCATION》2018,28(1):153-154

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Reading different orthographies: an fMRI study of phrase reading in Hindi–English bilinguals     

Uttam Kumar  Tanusree Das  Raju S. Bapi  Prakash Padakannaya  R. Malatesha Joshi  Nandini C. Singh 《Reading and writing》2010,23(2):239-255

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Plane curves of some geometrical significance and associated differential equations     

Jyoti Das 《Resonance》2010,15(6):573-580

Loci of points in the Euclidean plane are determined from prescribed relations of the points with given points, and/or, lines. The dependence of these relations on parameters lead to the diffrential equations representing the family of loci under concern. Incidentally most of the diffrential equations thus obtained are nonlinear ordinary diffrential equations.  相似文献   

Attitudes of secondary school teachers towards inclusive education in New Delhi,India     

Nisha Bhatnagar  Ajay Das 《Journal of Research in Special Educational Needs》2014,14(4):255-263

This study was undertaken to determine the attitudes of secondary regular schoolteachers towards the inclusion of students with disabilities in New Delhi. A total of 470 teachers, working in schools managed by a private organisation in Delhi, returned the completed survey. A two‐part questionnaire was used in this study. Part one gathered information relating to personal and professional characteristics of the teachers. Part two was a 16‐item Likert scale titled, Attitudes towards Inclusive Education Scale. The major finding of the study was that the teachers in Delhi had positive attitudes towards the inclusion of students with special needs. This study also indicated that the teachers who were more positive about inclusive education were male, younger teachers (less than 40 years of age), less experienced (less than 10 years) and had postgraduate qualifications. In addition, the teachers who had a contact with a person with a disability and those who did not have a focus on disability during their preservice teacher education programmes were more positive towards inclusive education.  相似文献   

Classroom     

Santanu Das  N. Kumar 《Resonance》2014,19(8):764-774

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Microscale experiments in chemistry — The need of the new millenium     

Shriniwas L. Kelkar  Dilip D. Dhavale  Prabodh G. Pol 《Resonance》2001,6(2):14-22

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Microscale experiments in chemistry — The need of the new millenium     

Shriniwas L. Kelkar  Dilip D. Dhavale 《Resonance》2000,5(12):6-11

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Validation Protocol: First Step of a Lean-Total Quality Management Principle in a New Laboratory Set-up in a Tertiary Care Hospital in India     

Das B 《Indian journal of clinical biochemistry : IJCB》2011,26(3):235-243

Method validation is pursued as the first step in establishing Lean-Total Quality Management in a new clinical laboratory, in order to eliminate error in test results. Validation of all the new tests were done (with particular reference to alkaline phosphatase) by verifying reference intervals, analytical accuracy and precision, inter-assay and intra-assay variations, analytical sensitivity, limit of detection, linearity and reportable range, i.e. (i) Analytical measurement range (AMR) and (ii) Clinically reportable range (CRR). Our obtained reference range was within that of the manufacturer’s and showed high degree of analytical accuracy between two laboratories (r ² = 0.99). Precision was comparable with the manufacturer’s claim with inter-assay variation CV 1.04% and intra-assay variation CV 1.54%. Lowest limit of detection was 1.0324 ± 0.007 with CV 0.34%. AMR was also verified with CV 1.26 and 0.69%, for level 1 and level 2 control sera, respectively. The assay was linear with different dilutions. Lean concept was also verified with high recovery percentage. Validation ensures that accurate and precise results are reported in a clinically relevant turn around time.  相似文献