RNA polymerase II — The transcription machine
Nobel prize in chemistry 2006     

Jiyoti Verma  Aruna Naorem  Anand Kumar  Manimala Sen  Parag Sadhale 《Resonance》2007,12(3):47-53

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Role of the National Institute for the Visually Handicapped in the Dissemination of Information to Visually Impaired People     

Shilpi Verma  Mega Arora 《图书馆管理杂志》2013,53(3):285-294

ABSTRACT

‘Disability’; the ‘D’ word generally speaks its own meaning, as anyone who is different from others in terms of physical and mental impairment. There are various types of disabilities; broad categories such as physical and communication disability, mental illness and mental retardation, learning disabilities and so forth. In this article, an attempt has been made to describe the term ‘visual impairment’ which falls under the category of physical and communication disability. The next section of the article presents activities of the National Institute for the Visually Handicapped, Dehradun, India to make the visually impaired self-sufficient and to recognize the role played by the Institute in disseminating information to them.  相似文献   

Curative effect of <Emphasis Type="Italic">Cynodon dactylon</Emphasis> against STZ induced hepatic injury in diabetic rats     

Santosh Kumar Singh  Prashant Kumar Rai  Shikha Mehta  Rakesh Kumar Singh  Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2009,24(4):410-413

The aim of the study was to ascertain the role of ethanolic extract of Cynodon dactylon against hepatic complications in streptozotocin (STZ) induced type 2 diabetic models. Effect of the pre identified most effective dose of 500 mg/kg body weight was studied on hepatic injury caused by chemically induced diabetes by 55 mg/kg body weight i.p. injection of STZ in male Wistar rats. The dose of 500mg/kg body weight given once daily for 14 days reduced the levels of serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase, creatinine and urine sugar significantly (P<0.05) with increase in total protein, haemoglobin and body weight was increased. High LD₅₀ validates its high margin of safety.  相似文献   

Antidiabetic effect of Withania coagulans in experimental rats     

Dolly Jaiswal  Prashant Kumar Rai  Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2009,24(1):88-93

The present study defines the systematic evaluation and the role of minerals in glycemic potential of aqueous extract of Withania coagulans fruits in order to develop an effective and safe alternative treatment for diabetes mellitus. Laser Induced Breakdown Spectroscopy was used for glycemic element detection. The study is based on the results of lowering in blood glucose levels of normal, sub, mild and severely diabetic rats assessed during fasting blood glucose, glucose tolerance test and post prandial glucose studies. The dose of 1000mg/ kg was identified as the most effective dose, which reduces the Fasting Blood Glucose level maximum by 33.2% at 4h in normal rats during fasting blood glucose studies. Glucose tolerance test studies of normal, sub and mild diabetic rats showed the maximum reduction of 15.7, 28.9 and 37.8% at 3h respectively. Long-term study in case of severely diabetic rats showed reduction of 52.9 and 54.1% in Fasting Blood Glucose and Post Prandial Glucose levels respectively after 30 days of treatment. The present study, besides confirming hypoglycemic and antidiabetic activities of aqueous extract of W. coagulans, helps in identifying the role of trace minerals like Mg & Ca responsible for antidiabetic potential of this potent indigenous shrub.  相似文献   

Genetic Variation in <Emphasis Type="Italic">CD166</Emphasis> Gene and Its Association with Bladder Cancer Risk in North Indian Population     

Archana Verma  Rakesh Kapoor  Rama Devi Mittal 《Indian journal of clinical biochemistry : IJCB》2017,32(3):292-300

Adhesion molecules play a key role in cancer progression and tumorigenesis. Genetic polymorphism of adhesion molecules may alter the normal functioning thereby leading to bladder cancer susceptibility. Hence we aimed to evaluate three SNPs of CD166 gene (CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G) in bladder cancer patients and normal controls of North Indian population. A total of 270 healthy controls and 240 confirmed bladder cancer patients were recruited for this study. Three SNPs of CD166 gene viz. CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G were selected for this study. CD166rs6437585 C/T and CD166rs10511244 C/T were genotyped by Taqman allelic discrimination assay and CD166rs1157 A/G was genotyped by PCR–RFLP. The statistical analysis was done using the SPSS software, version 16.0 (SPSS, Chicago, IL), and p < 0.05 was considered statistically significant. Haplotypic analysis was done by using SNP analyzer version 1.2A. CD166rs6437585 C/T and CD166rs10511244 C/T showed significant association with reduced risk in bladder cancer while CD166rs1157 A/G showed significant high risk along with association at genotypic and allelic levels. Haplotypic analysis showed 1.8-folds risk in CCG combination, whereas CTA and TCG showed significant association with reduced risk. Further stratification on the basis of smoking, tumor grade/stage and BGC therapy revealed no association of these three polymorphic sites of CD166. Our study suggests that CD166rs6437585 C/T and CD166rs10511244 C/T are predictive for the reduced risk of bladder cancer, whereas CD166rs1157 A/G had shown significant association with high risk of bladder cancer in North Indians. This somehow suggests that CD166rs1157 A/G can be used as a marker for risk prediction of bladder cancer.  相似文献   

The influence of parents on undergraduate and graduate students’ entering the STEM disciplines and STEM careers     

Cheryl J. Craig  Rakesh Verma  Donna Stokes  Paige Evans  Bobby Abrol 《International Journal of Science Education》2018,40(6):621-643

This research examines the influence of parents on students’ studying the STEM disciplines and entering STEM careers. Cases of two graduate students (one female, one male) and one undergraduate student (male) are featured. The first two students in the convenience sample are biology and physics majors in a STEM teacher education programme; the third is enrolled in computer science. The narrative inquiry research method is used to elucidate the students’ academic trajectories. Incidents of circumstantial and planned parent curriculum making surfaced when the data was serially interpreted. Other themes included: (1) relationships between (student) learners and (teacher) parents, (2) invitations to inquiry, (3) modes of inquiry, (4) the improbability of certainty, and (5) changed narratives?=?changed lives. While policy briefs provide sweeping statements about parents’ positive effects on their children, narrative inquiries such as this one illuminate parents’ inquiry moves within home environments. These actions became retrospectively revealed in their adult children’s lived narratives. Nurtured by their mothers and/or fathers, students enter STEM disciplines and STEM-related careers through multiple pathways in addition to the anticipated pipeline.  相似文献   

Study of glycemic profile of Cajanus cajan leaves in experimental rats     

Dolly Jaiswal  Prashant Kumar Rai  Amit Kumar  Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2008,23(2):167-170

The present study deals with the evaluation of glycemic profile of aqueous extract of Cajanus cajan leaves in streptozotocin induced type 2 diabetic rats. Single oral administration of graded doses of aqueous extract of Cajanus cajan leaves showed significant increment of 14.3 % in fasting blood glucose levels of normal rats. The sub diabetic and mild diabetic models have also shown hyperglycemic effect from the same variable doses of the extract. The dose of 1000 mg/kg showed the maximum rise of 17.1, 71.2 and 50.7 % in Blood glucose levels of normal, sub and mild diabetic rats respectively during glucose tolerance test. The study of leaves was taken into consideration on the basis of earlier reported hypoglycemic activity of Cajanus cajan seeds. However the results observed were found just opposite and therefore it may be useful in controlling hypoglycemia, occasionally caused due to excess of insulin and other hypoglycemic drugs.  相似文献   

Early childhood care and education in India     

Amita Verma 《International Journal of Early Years Education》1994,2(2):31-42

A brief history of the development of Early Childhood Care and Education in pre and post Independent India has been given first. The current situation of ECCE, teacher training and research has been described and the Research — Policy — Program interface has been delineated.

Among the myriad issues confronting ECCE in the country a few have been selected for discussion.  相似文献   

Technology Readiness, Learning Goals, and eLearning: Searching for Synergy     

Bo van der Rhee  Rohit Verma  Gerhard R. Plaschka  Jill R. Kickul 《Decision Sciences Journal of Innovative Education》2007,5(1):127-149

More and more business schools are offering classes online or classes using a mix of face‐to‐face and online elements. In this article, we focus on how technology readiness and learning‐goal orientation influence students' preference toward these mixed classes. We conducted a large‐scale survey to determine whether students who are technology ready would place higher utility on enrolling in mixed classes and/or whether there exists a participation bias such that students with low learning‐goal orientation place higher utility on enrolling in mixed classes. We found that overall students who are more technology ready do place higher utility on enrolling in mixed classes, but that learning‐goal orientation does not influence this decision. We conclude with implications and recommendations for business schools that are interested in offering mixed classes.  相似文献   

Some observations by an Indian visitor to the united states     

Jyoti Verma 《Int J Intercult Relat》1987,11(4)

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