In defence of children     

Suman Verma 《International Journal of Early Years Education》1995,3(1):70-73

The Convention on the rights of the child has not made much of a difference to the existing conditions of children in India. Moral energy and a socio‐political vision is required by not only the government, but all concerned to improve the status of the child in India. There is a need to focus on child rights issues related to creating public awareness, attitudinal change, political commitment, mass sensitisation and reaching the unreached. An appropriate action strategy is suggested for the restoration of the rights of children in India.  相似文献   

An IAD type framework for Blockchain enabled smart tourism ecosystem     

Janardan Krishna Yadav  Deepika Chandra Verma  Srinivas Jangirala  Shashi Kant Srivastava 《The Journal of High Technology Management Research》2021,32(1):100404

The concept of smart tourism remains fuzzy when it comes to practice because of the lack of clarity on the roles and responsibilities of stakeholders in addition to complex institutional ecosystem that exist within the tourism industry. Further, trust and safety of the data generated due to the advancement of smart tourism in varied institutional arrangements pose huge challenges. Extant literature proposes that the application of decentralized ledger promises possible solutions to most of these problems due to the inherent features of the Blockchain technology. This suggestion raises two practical questions. First, does the sophisticated additional layer adds complexity to its practical application? Second, will the suggested solutions really lead to a win-win for all the stakeholders involved? In this study, we use Ostrom's action arena to examine the exchanges (information, contractual and monetary) between various stakeholders in a BCT enabled smart tourism of a Blockchain enabled tourism industry to answer these two questions.  相似文献   

Combined Analysis of Anti SARS-CoV-2 IgG and IgM Responses in COVID19 Patients in India     

Mohana Kumari Chidananda  Deepy Zohmangaihi  Sant Ram  Shiv Lal Soni  Vikas Suri  Pankaj Malhotra  Ravjit Singh Jassal  Jyotdeep Kaur  Indu Verma  Sadhna Sharma 《Indian journal of clinical biochemistry : IJCB》2021,36(4):485

Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global health problem, India being the second most affected country. The kinetics of antibody response to SARS-CoV-2 in Indian population is not studied yet. To understand serological response in relation to age, gender, time period and severity of disease, Roche Elecsys anti-SARS-CoV-2 test was used which analysed both IgM and IgG. One hundred and three COVID-19 patients were enrolled. Seropositivity was seen in 64% of patients, with 33% at ≤ 7 days, 62% between 8 and 15 days and 81% at ≥ 16 days from the time of admission. Men (65%) showed higher antibody response than women (59%), whereas no difference was observed in seropositivity with respect to age of the patients. Dynamics of antibody responses revealed individual variations. Patients in ICU had higher antibody reactivity with 67% positivity as compared to 60% positivity in non-ICU patients. Kinetics of antibody response during COVID-19 disease varied in relation to gender, age, time period and severity and these factors might play an important role in treatment and control of COVID-19.  相似文献   

PCT as a Prognostic Marker in Cardiac Patients with Neutropenic Sepsis: Two Case Reports     

Neelima Verma  Shaloo Kapoor  Deepa Rao  Siddhartha Sharma  Anita Arora 《Indian journal of clinical biochemistry : IJCB》2014,29(1):107-111

Procalcitonin (PCT) is an innovative and highly specific marker for diagnosis of clinically relevant bacterial infection and sepsis. PCT supports early diagnosis and Clinical decision making. A retrospective study of two classical cases of neutropenic sepsis with elevated PCT levels in cardiac ICU was done. PCT was analyzed using Elecsys Brahms PCT kit. Serum PCT levels <0.5 ng/ml and ANC <1,000/mm³ was taken as cutoff. The first patient had initial high levels of PCT 100 ng/ml, TLC 13,600/mm³ and ANC 12,250/mm³. It was followed by drop with subsequent rise in PCT levels and drop in TLC 1,000/mm³ and ANC 70/mm³. The second patient had normal PCT 0.116 ng/ml, TLC 5,600/mm³ and ANC 4,420/mm³ levels followed with sharp increase in all the values with subsequent drop in TLC 2,000/mm³ and ANC 880 cells/mm³. Both the patients died of neutropenic sepsis with multiorgan failure. The case reports showed the correlation of PCT with TLC and ANC levels in predicting the mortality of patients with neutropenic sepsis in cardiac ICU.  相似文献   

Pedagogical responses to the changing position of girls and young women. Edited By Carrie Paechter,Rosalyn George and Angela McRobbie     

Geeta Ludhra 《British Journal of Educational Studies》2017,65(2):268-269

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Does LDL-C Estimation Using Anandaraja’s Formula Give a Better Agreement with Direct LDL-C Estimation than the Friedewald’s Formula?     

Shalini Gupta  Minni Verma  Kamaljit Singh 《Indian journal of clinical biochemistry : IJCB》2012,27(2):127-133

Estimation of low density lipoprotein cholesterol (LDL-C) is crucial in management of coronary artery disease patients. Though a number of homogenous assays are available for estimation of LDL-C, use of calculated LDL-C by Friedewald’s formula (FF) is common in Indian laboratories for logistic reasons. Recently Anandaraja and colleagues have derived a new formula for calculating LDL-C. This formula needs to be evaluated before it is extensively applied in diagnosis. We measured LDL-C by homogenous method (D-LDL-C) in 515 fasting samples. Friedewald’s and Anandaraja’s formulas were used for calculation of LDL-C (F-LDL-C and A-LDL-C, respectively). The mean LDL-C levels were 123.3 ± 53.2, 112.4 ± 50.2 and 109.2 ± 49.8 mg/dl for D-LDL-C, F-LDL-C and A-LDL-C, respectively. There was a statistically significant difference between the results (P > 0.001) obtained by calculation formulas compared to the measured LDL-C. There was underestimation of LDL-C by 10.8 and 14 mg/dl by Friedewald’s and Anandaraja’s formulas respectively. The Pearson’s correlation between F-LDL-C and D-LDL-C was 0.931 and that between A-LDL-C and D-LDL-C was 0.930. Bland–Altman graphs showed a definite agreement between mean and differences of the calculation formulas and direct LDL-C with 95% of values lying with in ±2 SD limits. The mean percentage difference (calculated as {(Calculated LDL-C)-(D-LDL-C)}/D-LDL-C × 100) for F-LDL-C was maximum (−11.6%) at HDL-C ≥ 60 mg/dl and TG levels of 200–300 mg/dl (−10.4%) compared to D-LDL-C. A-LDL-C results gave highest mean percentage difference at total cholesterol concentrations <100 mg/dl (−37.3%) and HDL-C < 40 mg/dl (−17.1%), respectively. The results of our study showed that FF is better in agreement with D-LDL-C than Anandaraja’s formula for estimation of LDL-C by calculation though both lead to its underestimation.  相似文献   

Conservatism and personality factors in a sample of adolescents     

Gajendra K. Verma 《Contemporary educational psychology》1978,3(1):51-56

Relationships between Cattell High School Personality Questionaire factors and the adolescent version of the Wilson-Patterson Conservatism Scale were examined in a sample of 492 teenagers. Conservatism was significantly related to a number of personality traits in both boys and girls. Results suggest the existence of a “conservative personality.”  相似文献   

Study of adenosine deaminase activity in pulmonary tuberculosis and other common respiratory diseases     

Meena Verma  Sanjeev Narang  Ashish Moonat  Akshra Verma 《Indian journal of clinical biochemistry : IJCB》2004,19(1):129-131

Tuberculosis has, in a short span of time, become a major health problem in the third world or developing countries like India. In view of this, a retrospective study was conducted to study Adenosine deaminase activity in serum and pleural fluid in patients affected with Pulmonary Tuberculosis and other common non-tubercular chronic respiratory diseases. The study was carried out on 100 patients suffering from various pulmonary disorders, between January 2002 and August 2002. Thirty-five normal healthy individuals were included as control subjects. ADA estimation was done by sensitive colorimetric method. The study revealed that the serum ADA activity was higher in patients of tuberculous pulmonary and pleural diseases and non-tuberculous pulmonary diseases than in control subjects. The mean serum ADA activity in the patients’ group was 35.5±6.93 u/l as compared to 16.20±2.85 u/l in control group, showing a highly significant (P≪0.001) difference. ADA activity was highest in tuberculous pleuropulmonary diseases. The pleural fluid ADA activity was higher in pyogenic pleural effusion than in tuberculous pleural effusion.  相似文献   

Comparing age-wise reference intervals for serum creatinine concentration in a “Reality check” of the recommended cut-off     

Mascha Verma  Rashmi Khadapkar  Priyadarshi Soumyaranjan Sahu  Bibhu Ranjan Das 《Indian journal of clinical biochemistry : IJCB》2006,21(2):90-94

An increase in the communication within the healthcare services, both nationally and internationally, has strengthened the need for harmonization of measurements and reference intervals in laboratory medicine. In the present report, the calculated reference interval for serum creatinine (sCr) levels of healthy normal individuals (n=1121) in different sex and age groups are compared with the established interval. The calculated reference interval for sCr level was 0.4–1.3 mg/dL and 0.6 to 1.3 mg/dL in the age groups of 21–40 and 41–60 years respectively. The difference between the mean sCr values in total males and total females (age range 21–60 years) was statistically significant (p<0.0001); When male and female subjects were analyzed age-group wise, the data showed a significant difference in mean sCr values (p<0.0001) in three age groups (21–30, 31–40 and 41–50 years) however, in older age group (51–60 years), the difference was non-significant (p=0.07). The reference ranges were 0.7–1.3 and 0.4–1.0 mg/dL for males and females respectively where the lower limit was 0.1–0.2 units less than that of standard limits. An increase in the mean value of sCr was observed particularly in females with an increase in age. Hence it is of interest to validate an age specific reference ranges for sCr in our population.  相似文献   

Antioxidants: Basis concepts in relation to the eye     

Pradeep Venkatesh  Garg Satpal  Lalit Verma  Tewari Hem Kumar  Sheena Garg 《Indian journal of clinical biochemistry : IJCB》2001,16(1):9-14

Antioxidants are a small group of substances that protect living cells from the destructive consequences of powerful oxidizing intermediates that can be formed from oxygen. Situations in which pro-oxidant mechanisms within the body are more active than the antioxidant mechanisms (oxidative stress) predispose and contribute to the pathogenesis of several ailments in various organs of the body. In the eye, pro-oxidant factors have been blamed for the causation of diseases such as age related macular degeneration and senile cataract. The role of pro-oxidants in the genesis of certain diseases is well established however, the effectivity of antioxidants provided to the body by dietary supplementation is inconclusive. In this article we provide a review on the basic concepts of antioxidant-pro-oxidant interaction in relation to its effects on the eye.  相似文献