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41.
Myokines may play a role in the health benefits of regular physical activity. Secreted protein acidic rich in cysteine (SPARC) is a pleiotropic myokine that has been shown to be released into the bloodstream by skeletal muscle in response to aerobic exercise. As there is evidence suggesting that SPARC release may be linked to glycogen breakdown and activation of 5’ adenosine monophosphate-activated protein kinase, we hypothesised that brief supramaximal exercise may also be associated with increased serum SPARC levels. In the present study, 10 participants (3 women; mean?±?SD age: 21?±?3 y, body mass index (BMI): 22?±?3?kg?m?2, and V˙O2max: 39?±?6?mL?kg?1?min?1) performed an acute bout of supramaximal cycle exercise (20-s Wingate sprint against 7.5% of body mass, with a 1-min warm-up and a 3-min cool-down consisting of unloaded cycling). Serum SPARC levels were determined pre-exercise as well as 0, 15, and 60?min post-exercise and corrected for plasma volume change. To determine whether regular exercise affected the acute SPARC response, participants repeated the acute exercise protocol three times per week for four weeks, and serum SPARC response to supramaximal exercise was reassessed after this period. Acute supramaximal exercise significantly decreased plasma volume (?10%; p?<?.001), but was not associated with a significant change in serum SPARC levels at either the pre-training or post-training testing sessions. In conclusion, in contrast to aerobic exercise, a single brief supramaximal cycle sprint is not associated with an increase in serum SPARC levels, suggesting that SPARC release is not related to skeletal muscle glycogen breakdown.  相似文献   
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Sedentary behaviour (SB) has recently emerged as an independent risk factor for different health outcomes. Older adults accumulate long time in SB. Understanding the role that SB plays on health is crucial for a successful aging. This short systematic review summarizes the current evidence related to the effects of objectively measured SB on frailty, physical performance and mortality in adults ≥60?years old. The literature search produced 271 records for physical performance (n?=?119), frailty (n?=?31), and mortality (n?=?121). Finally, only 13 articles fulfilled the inclusion criteria and were included in this review. All articles but one included in the physical performance section (n?=?9) showed a negative association between longer time spent in SB and physical performance. A significant association of SB with higher odds of frailty was found, however this association disappeared after adjusting for cognitive status. Lastly, two of the three included studies showed positive associations between SB and mortality, but this effect decreased or even disappeared in the more adjusted models. In conclusion, there is consistency that SB is negatively associated with physical performance. However, the relationship between objectively measured SB and frailty incidence and mortality rates remains unclear and deserves further research. The use of homogenous criteria to assess SB and the inclusion of more robust research designs will help clarifying the independent effects that SB could have on physical performance, frailty, and mortality. This will ultimately help designing more efficient and comprehensive physical activity guidelines for older adults.  相似文献   
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In the paper some case studies of damaged towers in Italy are presented: the Tower Masserano of Palace Ferrero - La Marmora at Biella, the bell tower of the Collegiata of San Vittore at Arcisate, and three medieval towers in Alba. A methodology is put forward for combining laboratory and nondestructive testing methods with monitoring systems in order to reach the goal of evaluating the state of conservation of historic towers and its evolution in time.  相似文献   
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The increasing awareness of some local and international authorities has promoted the appearance of new legislation and the rising of research works focused in the prevention of damage to the cultural heritage in karstic caves. Nevertheless, karstic areas usually imply complex studies, and a universal methodology is very difficult to establish. This work exposes the basic methodology for the geological risk assessment in archaeological site and/or rock art bearing karstic caves getting a strategy that provides flexibility to adjust specific methods according to the conditions of different cases. The integrated use of basic geological (mapping, petrology, stratigraphy…) and geotechnical (rock mass quality analytical methods and indexes) techniques used in engineering geology is proposed. Those techniques permit the geological characterization of the rock mass, the hazard identification and the analysis and the geological risk assessment of the research area. Obtained geological risk areas could be included in protection areas that could be used as the basis for the selection of the areas where further investigations and the application of prevention/mitigation measures would have a better cost/benefit ratio. The geological risk should be considered together with other type risk evaluations in order to define effective protection areas.  相似文献   
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English-Spanish cognates are an important subset of words in both the English and Spanish languages. Cognates are words that possess identical or nearly identical spellings and meanings in both languages as a result of being derived from Latin and Greek. Of major importance is the fact that many of the more than 20,000 cognates in English are academic vocabulary words, terms essential for comprehending school texts.

?The Pura Belpré Children's Book Award has been given since 1996 to outstanding children's and young adult literature that represents, affirms, and celebrates the Latino cultural experience. The books are judged for their literary and artistic quality.

?There are many English-Spanish cognates in each of the Pura Belpré picture books. The purpose of this article is to introduce the Pura Belpré Cognate Database, which lists all of the English-Spanish cognates for each of the children's picture books that have won the award or have been designated as honor books. Ideas for vocabulary, spelling, and morphology lessons or mini-lessons are also presented.  相似文献   
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RESUMEN

Para afirmarse como sujeto el niño debe ser capaz de percibirse como objeto. El reconocimiento del otro precede a la identificación de sí mismo. La imagen de sí mismo en el espejo se identifica antes de que el niño se reconozca en foto o en filme. Hacia los 2,5 años se produce este reconocimiento en foto o en filme sin ambigüedad, mientras que la identificación de la imagen especular continúa siendo “frágil”, posiblemente debido a la perplejidad o incertidumbre que suscita. A partir de la observación de las reacciones de niños ante un espejo y en un video de sí mismos, se investiga cómo y cuándo el niño construye su propia imagen. Hasta el tercer año de vida, la reacción del niño ante la imagen especular es como si viera a otro niño, dándose intercambios sociales. La reacción de perplejidad desaparece cuando se consigue la plena apropiación de la imagen.  相似文献   
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