Prostate specific antigen in patients of benign prostate hypertrophy and carcinoma prostate     

T. Malati  G. Rajani Kumari  P. V. L. N. Murthy  Ch. Ram Reddy  B. Surya Prakash 《Indian journal of clinical biochemistry : IJCB》2006,21(1):34-40

Prostate Specific Antigen (PSA) has emerged as the most applicable and important tumor marker for carcinoma prostate. In the present study PSA was determined in serum of healthy subjects, patients of benign prostate hypertrophy (BPH) and Carcinoma Prostate (Ca−P) to evaluate its diagnostic efficiency in day to day management of prostate cancer patients and in differentiating patients of early prostate cancer from those with BPH. Receiver operating characteristic curve (ROC) revealed 2 ng/ml and 10 ng/ml cut off serum PSA level for BPH and untreated carcinoma prostate patients (Ca−P). An extremely significant increase (P<0.0001) was observed in mean PSA concentration in BPH patients and adenocarcinoma prostate patients when compared to healthy males. Clinical relevance of PSA was highlighted by a case study of cancer patient prior to any therapy till death.  相似文献   

Infant joint attention, temperament, and social competence in preschool children   总被引：2，自引：0，他引：2  

Vaughan Van Hecke A  Mundy PC  Acra CF  Block JJ  Delgado CE  Parlade MV  Meyer JA  Neal AR  Pomares YB 《Child development》2007,78(1):53-69

Infant joint attention has been observed to be related to social-emotional outcomes in at-risk children. To address whether this relation is also evident in typically developing children, 52 children were tested at 12, 15, 24, and 30 months to examine associations between infant joint attention and social outcomes. Twelve-month initiating and responding to joint attention were related to 30-month social competence and externalizing behavior, even when accounting for 15-month temperament ratings, 24-month cognition and language, and demographic variables. These results suggest that, in addition to associations with language and cognition, infant joint attention reflects robust aspects of development that are related to individual differences in the emergence of social and behavioral competence in childhood.  相似文献   

ISM-CMAP-Combine (ICMC) for hierarchical knowledge scenario in quality engineering education     

R. K. Upadhyay  S. K. Gaur  V. P. Agrawal  K. C. Arora 《European Journal of Engineering Education》2007,32(1):21-33

Quality assurance in engineering education is a multifaceted problem further augmented by the stakeholders of engineering education. Students, parents and employers are rightfully questioning the quality of the curriculum, the instructional delivery, the learning environment, accessibility to learning technologies and equipment, employability as well as the possibilities of lifelong learning and the improvement of knowledge (Karapetrovic 2002 Karapetrovic, S. 2002. Why and how to develop a meaningful quality assurance system in engineering schools. Int. J. Engg. Educ, 18(3): 285–294. [Web of Science ®] [Google Scholar]). The purpose of the study is, therefore, to identify the parameters that influence the quality of an engineering education system and develop an integrated model of hierarchical structuring and a concept map for pre-identified concept elements through a process of iterative-interactive consensus-driven methodology, as advocated by second-generation system design paradigm for evolving knowledge scenario of concepts related to quality engineering education.  相似文献   

University press publishing and the ecology of disciplinary fluidity: General observations     

Jean-Pierre V. M. Hérubel 《Learned Publishing》2023,36(2):164-170

Academic book and journal publishing constitutes the majority focus of university presses. Besides commercial scholarly publishers, academic scholars and researchers view the opportunities provided by university presses as important venues for the dissemination of their research. This discussion focuses on the disciplinary imperative to publish scholarship that is ever more fluid and specialized as academic disciplines continue to become further nuanced in their response to the increasing knowledge produced by humanities and social science inquiry. The focus is on university presses and not commercial scholarly presses, although constitute a significant locus of scholarly publishing. What are the general characteristics of academic specialization and university press publishing? Further, how is disciplinary fluidity, especially evolving specialization, reflected in university press book publishing nomenclature and how scholarship is tied to the intellectual preoccupations of academic specialization? Multi- and inter-disciplinarities further articulate disciplinary publishing, accelerating disciplinary fluidity. Examples from disciplinary and emerging configurations of disciplinary nomenclature utilized by university presses offers insight into specialization and publishing. Academic history publishing is used to illustrate newly emerging fluid disciplinary configurations.  相似文献   

Literacy,languages and development in Africa: a policy perspective     

Robinson  Clinton  Vũ  Tú Anh Thị 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》2019,65(3):443-470

International Review of Education - In the multilingual environments of Africa, national literacy policies vary in terms of the attention they give to the roles and purposes of local, national and...  相似文献   

Genomics of adaptation and acclimation: from field to lab and back     

Scott V Edwards 《国家科学评论(英文版)》2020,7(1):128

  相似文献   

跨文化研究在线学习教育学——反思和比较中英高校在线学习合作项目的经验     

刘邦祥  D.麦康奈尔  V.拉利  S.班克 《开放教育研究》2006,12(4):46-50

本文旨在研究如何实现有效的跨文化协作,比较中英两国如何理解和组织在线学习。研究者依据现象解释学设计研究方法,对比和反思了参加跨文化合作开发在线学习课程的经历和体验,讨论了这一基于项目的协作交流如何促进了对在线学习的理解。最后,本文总结了一些可供开展后续相关探索活动的尝试性结论。  相似文献   

Item wording and internal consistency of a measure of cohesion: the group environment questionnaire     

Eys MA  Carron AV  Bray SR  Brawley LR 《运动与训练心理学杂志》2007,29(3):395-402

A common practice for counteracting response acquiescence in psychological measures has been to employ both negatively and positively worded items. However, previous research has highlighted that the reliability of measures can be affected by this practice (Spector, 1992). The purpose of the present study was to examine the effect that the presence of negatively worded items has on the internal reliability of the Group Environment Questionnaire (GEQ). Two samples (N = 276) were utilized, and participants were asked to complete the GEQ (original and revised) on separate occasions. Results demonstrated that the revised questionnaire (containing all positively worded items) had significantly higher Cronbach alpha values for three of the four dimensions of the GEQ. Implications, alternatives, and future directions are discussed.  相似文献   

Optimized versus corrected peak power during friction-braked cycle ergometry in males and females     

James DV  Wood DM  Maberly TC  De Ste Croix M 《Journal of sports sciences》2007,25(8):859-867

The aim of this study was to compare optimization and correction procedures for the determination of peak power output during friction-loaded cycle ergometry. Ten male and 10 female sports students each performed five 10-s sprints from a stationary start on a Monark 864 basket-loaded ergometer. Resistive loads of 5.0, 6.5, 8.0, 9.5, and 11.0% body weight were administered in a counterbalanced order, with a recovery period of 10 min between sprints. Peak power was greater and occurred earlier, with less work having been done before the attainment of peak power, when the data were corrected to account for the inertial and frictional characteristics of the ergometer. Corrected peak power was independent of resistive load (P > 0.05), whereas uncorrected peak power varied as a quadratic function of load (P < 0.001). For males and females, optimized peak power (971 +/- 122 and 668 +/- 37 W) was lower (P < 0.01) than either the highest (1074 +/- 111 and 754 +/- 56 W respectively) or the mean (1007 +/- 125 and 701 +/- 45 W respectively) of the five values for corrected peak power. Optimized and mean corrected peak power were highly correlated both in males (r = 0.97, P < 0.001) and females (r = 0.96, P < 0.001). The difference between optimized and mean corrected peak power was 37 +/- 30 W in males and 33 +/- 14 W in females, of which approximately 15 W was due to the correction for frictional losses. We conclude that corrected peak power is independent of resistive load in males and females.  相似文献   

Relationship between maximal oxygen uptake and oxygen uptake attained during treadmill middle-distance running     

James DV  Sandals LE  Draper SB  Wood DM 《Journal of sports sciences》2007,25(8):851-858

Traditionally, it has been assumed that during middle-distance running oxygen uptake (VO2) reaches its maximal value (VO2max) providing the event is of a sufficient duration; however, this assumption is largely based on observations in individuals with a relatively low VO2max. The aim of this study was to determine whether VO2max is related to the VO2 attained (i.e. VO2peak) during middle-distance running on a treadmill. Fifteen well-trained male runners (age 23.3 +/- 3.8 years, height 1.80 +/- 0.10 m, body mass 76.9 +/- 10.6 kg) volunteered to participate in the study. The participants undertook two 800-m trials to examine the reproducibility of the VO2 response. These two trials, together with a progressive test to determine VO2max, were completed in a randomized order. Oxygen uptake was determined throughout each test using 15-s Douglas bag collections. Following the application of a 30-s rolling average, the highest VO2 during the progressive test (i.e. VO2max) was compared with the highest VO2 during the 800-m trials (i.e. VO2peak) to examine the relationship between VO2max and the VO2 attained in the 800-m trials. For the 15 runners, VO2max was 58.9 +/- 7.1 ml x kg(-1) x min(-1). Two groups were formed using a median split based on VO2max. For the high and low VO2max groups, VO2max was 65.7 +/- 3.0 and 52.4 +/- 1.8 ml x kg(-1) x min(-1) respectively. The limits of agreement (95%) for test-retest reproducibility for the VO2 attained during the 800-m trials were +/- 3.5 ml x kg(-1) x min(-1) for a VO2peak of 50.6 ml x kg(-1) x min(-1) (the mean VO2peak for the low VO2max group) and +/- 2.3 ml x kg(-1) x min(-1) for a VO2peak of 59.0 ml x kg(-1) x min(-1) (the mean VO2peak for the high VO2max group), with a bias in VO2peak between the 800-m runs (i.e. the mean difference) of 1.2 ml x kg(-1) x min(-1). The VO2peak for the 800-m runs was 54.8 +/- 4.9 ml x kg(-1) x min(-1) for all 15 runners. For the high and low VO2max groups, VO2peak was 59.0 +/- 3.3 ml x kg(-1) x min(-1) (i.e. 90% VO2max) and 50.6 +/- 2.0 ml x kg(-1) x min(-1) (i.e. 97% VO2max) respectively. The negative relationship (-0.77) between VO2max and % VO2max attained for all 15 runners was significant (P = 0.001). These results demonstrate that (i) reproducibility is good and (ii) that VO2max is related to the %VO2max achieved, with participants with a higher VO2max achieving a lower %VO2max in an 800-m trial on a treadmill.  相似文献