Using clinical guidelines to assess the potential value of laboratory medicine in clinical decision-making     

Allan J. Hicks  Zoe L. Carwardine  Mike J. Hallworth  Eric S. Kilpatrick 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(1)

IntroductionIt is often quoted that 70% of clinical decisions are based on laboratory results, but the evidence to substantiate this claim is lacking. Since clinical guidelines aim to document best-practice decision making for specific disease conditions, inclusion of any laboratory test means that the best available evidence is recommending clinicians use it. Cardiovascular disease (CVD) is the world’s most common cause of mortality, so this study reviewed all CVD guidelines published by five national/international authorities to determine what proportion of them recommended laboratory testing.Materials and methodsFive leading CVD guidelines were examined, namely the European Society of Cardiology (ESC), the UK National Institute for Health and Clinical Excellence (NICE), the American College of Cardiology (ACC), the Australian Heart Foundation (AHF) and the Cardiac Society of Australia and New Zealand (CSANZ).ResultsA total of 101 guidelines were reviewed. Of the 33 individual ESC guidelines relating to CVD, 24/33 made a direct reference to the use of clinical laboratory tests in either diagnosis or follow-up treatment. The same applied to 15/20 of NICE guidelines, 24/32 from the ACC and 15/16 from the AHF/CSANZ. Renal function and blood count testing were the most recommended (39 and 26 times), with lipid, troponin and natriuretic peptide measurement advocated 25, 19 and 19 times respectively.ConclusionsThis study has shown that laboratory testing is advocated by between 73% and 94% of individual CVD guideline recommendations from five national/international authorities. This provides an index to assess the potential value of laboratory medicine to healthcare.  相似文献   

We do language: English language variation in the secondary English classroom,by Anne H. Charity Hudley and Christine Mallinson     

Mike Metz 《Pedagogies: An International Journal》2014,9(3):275-277

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The importance of content and context     

Judith Breen  Mike Pedler  John Edmonstone 《Action Learning: Research and Practice》2014,11(2):233-234

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Development, Implementation, and Validation of a Computerized Test for Statewide Assessment     

James B. Olsen  Apryl Cox  Charles Price  Mike Strozeski  Idolina Vela 《Educational Measurement》1990,9(2):7-10

How does a testing component function in an integrated learning system? How can you customize computerized tests to meet local specifications? How are computerized tests implemented and evaluated? Is the pay-off of computerized testing justified?  相似文献   

The Guilt of Whistling-blowing: Conflicts in Action Research and Educational Ethnography     

Mike McNamee 《Journal of Philosophy of Education》2001,35(3):423-441

This chapter discusses the role conflict of the educational researcher who comes upon an unprofessional relationship between teacher and pupil. It is argued that the whistleblowing literature in related professions, with its focus on standard conditions and solutions framed as obligations, is inadequate. Reference is made to the idea of 'guilty knowledge': the feelings of guilt that attach when one comes to know of harm visited on innocent others, and has no unqualified sense of which way to act. Distinguishing moral from causal responsibility helps to show how blame need not necessarily attach to the guilt-ridden researcher, whichever option she chooses.  相似文献   

The musical field     

Professor Mike Savage 《Cultural Trends》2006,15(2-3):159-174

This article examines musical taste, as revealed by the Cultural Capital and Social Exclusion survey. It shows that musical taste is highly divided and contentious, with large numbers of people intensely disliking certain genres of music. It shows the existence of two distinctive musical taste communities, one linking taste for rock, electronic, urban, world and heavy metal music, and the other linking classical music and jazz. Tastes for specific musical works do not easily map onto musical genres, and are less closely correlated with each other. Using logistic regression, it is shown that age and ethnicity in particular, and gender, educational qualifications and occupational class, strongly condition taste for both musical genres and works.  相似文献   

Effective practice with e-learning     

Mike Johnson 《British journal of educational technology : journal of the Council for Educational Technology》2005,36(4):697-698

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Other Voices     

Mike Torbe 《English in Education》1981,15(1):54-56

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SOFTWARE REVIEW: The Student Edition of MINITAB Release 8     

Mike Fuller 《Teaching Statistics》1994,16(1):12-14

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Other Voices     

Mike Torbe 《English in Education》1979,13(3):70-72

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