Immunoisolated Transplantation of Purified Langerhans Islet Cells in Testis Cortex of Male Rats for Treatment of Streptozotocin Induced Diabetes Mellitus     

Ali Farhangi  Dariush Norouzian  Mohammad Reza Mehrabi  Mohsen Chiani  Zahra Saffari  Maryam Farahnak  Azim Akbarzadeh 《Indian journal of clinical biochemistry : IJCB》2014,29(4):406-417

The objective of this study is to induce experimental diabetes mellitus by streptozotocin in normal adult Wistar rats via comparison of changes in body weight, consumption of food, volume of water, urine and levels of glucose, insulin and C-peptide in serum, between normal and diabetic rats. Intra-venous injection of 60 mg/kg dose of streptozotocin in 250–300 g (75–90 days) adult Wistar rats makes pancreas swell and causes degeneration in Langerhans islet β-cells and induces experimental diabetes mellitus in 2–4 days. For a microscopic study of degeneration of Langerhans islet β-cells of diabetic rats, biopsy from pancreas tissue of diabetic and normal rats, staining and comparison between them, were done. In this process, after collagenase digestion of pancreas, islets were isolated, dissociated and identified by dithizone method and then with enzymatic procedure by DNase and trypsin, the islet cells changed into single cells and β-cells were identified by immune fluorescence method and then assayed by flow-cytometer. Donor tissue in each step of work was prepared from 38 adult male Wistar rats weighted 250–300 g (75–90 days). Transplantation was performed in rats after 2–4 weeks of diabetes induction. In this study, the levels of insulin, C-peptide and glucose in diabetic rats reached to normal range as compared to un-diabetic rats in 20 days after transplantation of islet cells. Transplantation was performed under the cortex of testis as immunoisolated place for islet cells transplantation.  相似文献   

Measurement and control of pressure driven flows in microfluidic devices using an optofluidic flow sensor     

Mohammad Sadegh Cheri  Hamidreza Shahraki  Jalal Sadeghi  Mohammadreza Salehi Moghaddam  Hamid Latifi 《Biomicrofluidics》2014,8(5)

Measurement and control of pressure-driven flow (PDF) has a great potential to enhance the performance of chemical and biological experiments in Lab on a Chip technology. In this paper, we present an optofluidic flow sensor for real-time measurement and control of PDF. The optofluidic flow sensor consists of an on-chip micro Venturi and two optical Fabry-Pérot (FP) interferometers. Flow rate was measured from the fringe shift of FP interferometers resulted from movement fluid in the on-chip micro Venturi. The experimental results show that the optofluidic flow sensor has a minimum detectable flow change of 5 nl/min that is suitable for real time monitoring and control of fluids in many chemical and biological experiments. A Finite Element Method is used to solve the three dimensional (3D) Navier–Stokes and continuity equations to validate the experimental results.  相似文献   

Feedback after good versus poor trials affects intrinsic motivation     

Badami R  VaezMousavi M  Wulf G  Namazizadeh M 《Research quarterly for exercise and sport》2011,82(2):360-364

  相似文献   

The Master’s Program in Computer-Mediated Computer Communications: A Comparative Study of Two Cohorts of Students     

Mohammad Issack Santally  Jerome Raverdy 《Educational technology research and development : ETR & D》2006,54(3):312-326

  相似文献   

Antagonistic interaction between <Emphasis Type="Italic">Trichoderma asperellum</Emphasis> and <Emphasis Type="Italic">Phytophthora capsici</Emphasis> in vitro     

Heng Jiang  Liang Zhang  Jing-ze Zhang  Mohammad Reza Ojaghian  Kevin D. Hyde 《Journal of Zhejiang University. Science. B》2016,17(4):271-281

Phytophthora capsici is a phytopathogen that causes a destructive pepper blight that is extremely difficult to control. Using a fungicide application against the disease is costly and relatively ineffective and there is also a huge environmental concern about the use of such chemicals. The genus Trichoderma has been known to have a potential biocontrol issue. In this paper we investigate the mechanism for causing the infection of T. asperellum against P. capsici. Trichoderma sp. (isolate CGMCC 6422) was developed to have a strong antagonistic action against hyphae of P. capsici through screening tests. The strain was identified as T. asperellum through using a combination of morphological characteristics and molecular data. T. asperellum was able to collapse the mycelium of the colonies of the pathogen through dual culture tests by breaking down the pathogenic hyphae into fragments. The scanning electron microscope showed that the hyphae of T. asperellum surrounded and penetrated the pathogens hyphae, resulting in hyphal collapse. The results show that seven days after inoculation, the hyphae of the pathogen were completely degraded in a dual culture. T. asperellum was also able to enter the P. capsici oospores through using oogonia and then developed hyphae and produced conidia, leading to the disintegration of the oogonia and oospores. Seven days after inoculation, an average 10.8% of the oospores were infected, but at this stage, the structures of oospores were still intact. Subsequently, the number of infected oospores increased and the oospores started to collapse. Forty-two days after inoculation, almost all the oospores were infected, with 9.3% of the structures of the oospores being intact and 90.7% of the oospores having collapsed.  相似文献   

Learning communities and fair trade in doctorates and development: report of a collaborative project     

Janinka Greenwood  Safayet Alam  Abu Nayeem Mohammad Salahuddin  Mollah Mohammed Haroon-Ar Rasheed 《Globalisation, Societies & Education》2016,14(1):49-67

This article reports the second stage of a study examining an academic partnership in which Bangladeshi doctoral students in a western university focus their research in the grounded context of Bangladesh and investigate the processes for change. After briefly outlining the previous published stage which examined the academic trade in higher education with developing countries, the article builds on the concept of fair academic trade to critically reflect on the development of a doctoral learning community, a publication project and three specific doctoral studies. The methodological approach is one of participatory action research, with focus on critical reflection on practice.  相似文献   

Learner satisfaction,engagement and performances in an online module: Implications for institutional e-learning policy     

Rajabalee  Yousra Banoor  Santally  Mohammad Issack 《Education and Information Technologies》2021,26(3):2623-2656

Education and Information Technologies - There has been debates related to online and blended learning from a perspective of learner experiences in terms of student satisfaction, engagement and...  相似文献   

Malaysian university students' attitudes to academic dishonesty and business ethics     

Zauwiyah Ahmad  Maimun Simun  Junaini Mohammad 《Asia Pacific Journal of Education》2008,28(2):149-160

Academic dishonesty is believed to have predictive ability for subsequent behaviours in the workplace. This study adds to the literature by investigating Malaysian business students' attitudes to academic dishonesty and their attitudes to ethics issues in business. This study also explores the association between these two constructs. The form of academic dishonesty being investigated here is related to assignments, quizzes, and examinations. Employing data collected from 153 business students from different academic years, this exploratory study concludes that business students may have found that some level of dishonesty is acceptable in some academic settings as well as in business settings. The study's outcomes highlight the possibility of using students' attitudes to academic dishonesty to explain their attitudes to ethics in business contexts. The findings of this study, to a certain extent, indicate that years spent in business education might contribute to such unfavourable attitudes. This exploratory study also draws attention to several issues related to the teaching of ethics within business education.  相似文献   

Current Developments in Research on the Teaching of Grammar     

Hossein Nassaji Sandra Fotos 《通化师范学院学报》2006,(4):35-40

There are a number of studies that have investigated the effects of textual enhancement on drawing the learner＇s attention to grammar, and the method has been described as the least explicit and the least intrusive method of focus on form （Doughty ＆ Varela, 1998）. It involves highlighting certain features of input that might go unnoticed under normal circumstances by typographically manipulating them through boldfacing, italicizing, underlining, or capitalizing. The assumption is that such manipulations enhance the perceptual saliency of the target structures, and this, hence, increases their chance of being notieed. A related technique is the provision of numerous instances of target linguistic forms in the input, called an inputflood （Trahey ＆ While, 1993）. Again, the assumption is that frequent exposure to target items enhances their saliency and hence results in noticing the forms （ Schmidt, 1990; Sharwood Smith, 1993）. Whereas studies by Doughty （1991） and Fotos （1994） reported positive results in terms of awareness of target structures and proficiency gains resulting from textually enhanced structures,  相似文献   

Effects of within-class ability grouping on social interaction,achievement, and motivation     

Mohammad?Saleh  Ard?W.?LazonderEmail author  Ton?De Jong 《Instructional Science》2005,33(2):105-119

This study examined how grouping arrangements affect students achievement, social interaction, and motivation. Students of high, average and low ability were randomly assigned to homogeneous or heterogeneous ability groups. All groups attended the same plant biology course. The main results indicate that low-ability students achieve more and are more motivated to learn in heterogeneous groups. Average-ability students perform better in homogeneous groups whereas high-ability students show equally strong learning outcomes in homogeneous and heterogeneous groups. Results on social interaction indicate that heterogeneous groups produce higher proportions of individual elaborations, whereas homogeneous groups use relatively more collaborative elaborations. In the discussion, these differences in social interaction are used to explain the differential effects of grouping arrangements on achievement scores. Practical implications are discussed and topics for further research are advanced.  相似文献