Planar lens integrated capillary action microfluidic immunoassay device for the optical detection of troponin I     

Mazher-Iqbal Mohammed  Marc P. Y. Desmulliez 《Biomicrofluidics》2013,7(6)

Optical based analysis in microfluidic and lab-on-a-chip systems are currently considered the gold standard methodology for the determination of end point reactions for various chemical and biological reaction processes. Typically, assays are performed using bulky ancillary apparatus such as microscopes and complex optical excitation and detection systems. Such instrumentation negates many of the advantages offered by device miniaturisation, particularly with respect to overall portability. In this article, we present a CO₂ laser ablation technique for rapidly prototyping on-chip planar lenses, in conjunction with capillary action based autonomous microfluidics, to create a miniaturised and fully integrated optical biosensing platform. The presented self-aligned on-chip optical components offer an efficient means to direct excitation light within microfluidics and to directly couple light from a LED source. The device has been used in conjunction with a miniaturised and bespoke fluorescence detection platform to create a complete, palm sized system (≈60 × 80 × 60 mm) capable of performing fluoro-immunoassays. The system has been applied to the detection of cardiac Troponin I, one of the gold standard biomarkers for the diagnosis of acute myocardial infarction, achieving a lower detection limit of 0.08 ng/ml, which is at the threshold of clinically applicable concentrations. The portable nature of the complete system and the biomarker detection capabilities demonstrate the potential of the devised instrumentation for use as a medical diagnostics device at the point of care.  相似文献   

The Impact of Bombing Attacks on Civilians in Iraq     

Fuaad Mohammed Freh  Rudi Dallos  Man Cheung Chung 《International journal for the advancement of counseling》2013,35(4):273-285

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Two Plausible Indicators to Use with State Accountability Measures: An Analysis of NAEP Math Data     

David A. Walker  Shereeza F. Mohammed 《The Educational forum》2013,77(2):177-186

Using National Assessment of Educational Progress mathematics data, a predictive model indicated that states could be classified as “No Score Gain” or “Score Gain” states based on median household income and the percentage of students participating in free and reduced-price lunch. Implications associated with the findings suggested that these two indicators could be used in adjusting or customizing Adequate Yearly Progress targets in schools serving impoverished communities. The result would be that Adequate Yearly Progress targets would be more realistic, and schools and their stakeholders would realize continuous improvement if incremental increases in expected growth were monitored and maintained.  相似文献   

Reduction of the non-uniform illumination using nonlocal variational models for document image analysis     

Fatim Zahra Ait Bella  Mohammed El Rhabi  Abdelilah Hakim  Amine Laghrib 《Journal of The Franklin Institute》2018,355(16):8225-8244

In this paper, we investigate two new reflectance and illumination decomposition models based on a nonlocal partial differential equation (PDE) applied to text images. Taking into consideration the higher regularity level of the illumination compared to the reflectance, we propose a nonlocal PDE which deals with repetitive structures and textures that characterize the text image much better compared to the classical local PDEs. The aim of this approach is to use the repetitive features of the reflectance to efficiently extract it from the non-uniform illumination. This idea is motivated by extending the range of application of the nonlocal operators to such a problem. Numerical experiments on both grayscale and color text images show the performance and strength of the proposed nonlocal PDE.  相似文献   

What Did It Take to Scale Up and Sustain Udaan,a School-Based Adolescent Education Program in Jharkhand,India?     

Venkatraman Chandra-Mouli  Marina Plesons  Alka Barua  Aparajita Gogoi  Manju Katoch  Mohammed Ziauddin 《American journal of sexuality education》2018,13(2):147-169

Since 2006, Udaan—a school-based adolescent education program in Jharkhand, India—was the only at-scale state-run program in the country. To determine factors that contributed to Udaan's scale-up and longevity, this study drew information from programmatic reports and interviews with the Centre for Catalyzing Change staff. Key factors for Udaan's success included an enabling policy environment, a willing government that supported and operationalized the program, a knowledgeable and committed NGO partner, sustained funding, and a commitment to constant improvement through evaluation. Udaan provides an example of a well-designed, implemented, and evaluated school-based adolescent health program that has been operating at scale over a sustained period. Other programs in India and elsewhere can benefit from learning from Udaan's experience.  相似文献   

The impact of video modelling on improving social skills in children with autism          下载免费PDF全文

Mohammed Alzyoudi  AbedAlziz Sartawi  Osha Almuhiri 《British Journal of Special Education》2015,42(1):53-68

Children with autism often show a lack of the interactive social skills that would allow them to engage with others successfully. They therefore frequently need training to aid them in successful social interaction. Video modelling is a widely used instructional technique that has been applied to teach children with developmental disabilities such as autism, and has been shown to be effective in teaching a variety of skills. The aim of this study is to evaluate the impact of video modelling on social skills development in children with autism living in the United Arab Emirates. The research was carried out by Mohammed Alzyoudi, AbedAlziz Sartawi and Osha Almuhiri, all from the United Arab Emirates University. A sample of five boys with autism was chosen to participate in this study. The boys ranged in age between five and seven years. Each child was asked to watch a videotape which presented two individuals interacting in a role‐play setting. One person portrayed a therapist giving cues, while the second portrayed a child acting appropriately and demonstrating correct social behaviours. The boys were then asked to complete a social task and their performance was compared against baseline assessment measures. The results of this study indicate that this is an effective instruction method. Results are discussed and implications for further research and practice are provided.  相似文献   

Comments on Ibrahim Odeh's “The education of an industrial middle class in Arab-Islamic countries”     

Ovey N. Mohammed 《Interchange》1994,25(3):305-308

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Finite element analysis of dynamic stability of skeletal structures under periodic loading     

THANA Hemantha Kumar AMEEN Mohammed 《浙江大学学报(A卷英文版)》2007,8(2):245-256

INTRODUCTION Some structures fail geometrically before thestrength failure because of lack of stability and such afailure is known as instability failure or bucklingfailure. Determination of buckling load is importantin order to ensure the stability of a structure. If thestructure under consideration is subjected to a dy-namic load then this problem comes under the pur-view of dynamic stability problems. Examples areslender offshore structures subjected to periodic ex-citations and colum…  相似文献   

Parent-Infant Rough Play: Its Cultural Specificity     

Jaipaul L. Roopnarine  Mohammed Ahmeduzzaman  Ziarat Hossain  Nancy Beth Riegraf 《Early education and development》1992,3(4):298-311

The salience of father-infant rough play in some industrialized and nonindustrialized countries around the world was reviewed, and data were presented on the physical play interactions of 34Indianmothers and fathers with their year-old infants in the home. Our review of the parent-infant physical play literature failed to show that fathers had a uniformly greater propensity to engage in vigorous rough activity with infants than mothers did. The data from the observational study suggest that Indian parents are not vigorous play partners to infants. Mothers were more likely to engage in object-mediated play than were fathers. In total, the data reviewed do not support the contention that rough play is a major activity between fathers and infants across cultures. Rather, the data from parent-infant play in the nonindustrialized countries suggest that rough play may be culture specific, casting doubts about its biological underpinnings.  相似文献   

A comparative study of conventional and supercritical fluid extraction methods for the recovery of secondary metabolites from <Emphasis Type="Italic">Syzygium campanulatum</Emphasis> Korth     

Abdul Hakeem Memon  Mohammad Shahrul Ridzuan Hamil  Madeeha Laghari  Fahim Rithwan  Salman Zhari  Mohammed Ali Ahmed Saeed  Zhari Ismail  Amin Malik Shah Abdul Majid 《Journal of Zhejiang University. Science. B》2016,17(9):683-691

Syzygium campanulatum Korth is a plant, which is a rich source of secondary metabolites (especially flavanones, chalcone, and triterpenoids). In our present study, three conventional solvent extraction (CSE) techniques and supercritical fluid extraction (SFE) techniques were performed to achieve a maximum recovery of two flavanones, chalcone, and two triterpenoids from S. campanulatum leaves. Furthermore, a Box-Behnken design was constructed for the SFE technique using pressure, temperature, and particle size as independent variables, and yields of crude extract, individual and total secondary metabolites as the dependent variables. In the CSE procedure, twenty extracts were produced using ten different solvents and three techniques (maceration, soxhletion, and reflux). An enriched extract of five secondary metabolites was collected using n-hexane:methanol (1:1) soxhletion. Using food-grade ethanol as a modifier, the SFE methods produced a higher recovery (25.5%?84.9%) of selected secondary metabolites as compared to the CSE techniques (0.92%?66.00%).  相似文献