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71.
Kiran Dahiya A. D. Tiwari Vijay Shankar Simmi Kharb Rakesh Dhankhar 《Indian journal of clinical biochemistry : IJCB》2006,21(1):157-160
Phototherapy has been related to increased oxidative stress and lipid peroxidation. In the present study, thirty full term
jaundiced neonates with appropriate weight were analyzed before and after completion of phototherapy for malondialdehyde (MDA),
reduced glutathione (GSH), total thiols, vitamin C and superoxide dismutase (SOD) levels in hemolysate and albumin levels
in plasma. These parameters were analyzed in cord blood samples of 20 healthy neonates as control. It was observed that levels
of MDA were elevated significantly (p<0.001) in patients as compared to controls and that the levels increased significantly
after phototherapy (p<0.001). Levels of SOD were also found to be increased significantly as compared to controls and the
levels rose after phototherapy (p<0.001). On the other hand, the levels of non-enzymatic antioxidants such as GSH, total thiols
and vitamin C were significantly low (p<0.001) as compared to controls and the levels decreased significantly after phototherapy
(p<0.001). The plasma albumin levels also were found to be decreased significantly after phototherapy (p<0.01). Therefore,
phototherapy increases oxidative stress and should be used with care. 相似文献
72.
Rama D. Mittal Hemant K. Bid Parmeet K. Manchanda Rakesh Kapoor 《Indian journal of clinical biochemistry : IJCB》2008,23(2):106-116
Urolithiasis is a relevant clinical problem with a subsequent burden for health system. The aim of this review is to provide
recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for kidney stone disease
and to predict treatment response. Population case-control studies are useful both as an alternative and an adjunct as compared
to family studies. These involve either whole genome scanning or candidate gene approaches. While whole genome scanning is
likely to be widely used in future, at present, candidate gene studies are more feasible. When performing candidate gene case-control
studies factors such as study design, methods for recruitment of case and controls, selection of candidate genes, functional
significance of polymorphisms chosen for study and statistical analysis require close attention to ensure that only genuine
associations are detected. Some of the significant genes that play role in stone formation include calcitonin receptor gene
(CTR), vitamin D receptor (VDR), Urokinase, Interleukin, (IL-1β, IL-Ra), E-Cadherin, Androgen & oestrogen receptor gene, vascular
endothelial growth factor (VEGF) and Arginine p21. In our case-control study we studied CTR, VDR, Urokinase, IL-1β(−511 and
+3954), IL-Ra from north India and predict that VDR, IL-β (-511) and IL-1Ra gene may be used as a possible genetic marker
for earlier detection in patients who are at risk for calcium oxalate stone disease. Further, linkage disequilibrium and haplotype
structure of a certain candidate gene is important for association analysis. When a certain polymorphic allele has been found
to be associated with disease, it is further explained on basis of LD and haplotype structure by one or more other alleles.
Once it is determined which haplotype carries the risk allele, by means of molecular biological functional analyses, the variants
on that haplotype allele truly causing the effect can be determined. 相似文献
73.
74.
This paper deals with the analytical and experimental investigations of an open-loop pulse-width-modulated d.c. motor speed control system. The analysis is carried out by two different approaches, circuit approach and the lattice function approach. From the circuit approach, the relationship between the current-ripple-factor and the pulse width is obtained. The lattice function approach yields the relationship between pulse width and the speed variation. There is good correlation between the experimental and theoretical results. 相似文献
75.
Satish Verma 《The Journal of Agricultural Education and Extension》2013,19(4):255-258
Abstract The threats to traditional cultural landscapes and the concomitant demands from society for remedial landscape management represent a new challenge for agricultural education. The research described here examined the extent to which relevant landscape management skills and knowledge are transferred to would-be farmers (if at all) within the Austrian agricultural school system. A plurilateral approach was taken, involving a standardised text evaluation of curricula (as defined in legislative documents), examination of further vocational training programmes for teachers, and investigation of the actual teaching situation in selected schools. This combination of methods produced a comprehensive overview of the situation in agricultural schools and academies with regard to landscape management teaching. The teaching programmes prescribed by law and the actual programmes carried out by teachers were compared with a theoretical ‘best-case’ programme for teaching landscape management, and this revealed considerable shortcomings in current teaching. The research also identified potential constraints to the integration of landscape management elements within the agricultural school system. 相似文献
76.
77.
S. S. Verma 《Resonance》2001,6(10):57-67
Refrigeration applications at the domestic, commercial and industrial levels are becoming an integral part of the present
day living. The demand and supply of refrigeration systems is increasing day by day with the changing lifestyle. The existing
compressor-based refrigeration (i.e., mechanical refrigeration) system has reached the maximum level of innovation. For the
last few decades, there has not been any significant increase in the efficiency (i.e., coefficient of performance, COP) of
the system. Moreover, with the increasing awareness of environmental degradation, the production, use and disposal of ChloroFluoro
Carbons (CFCs) and HydroChloroFluoroCarbons (HCFCs) as refrigerants in mechanical refrigeration system has become a subject
of great concern. However, such systems are being developed using more ecofriendly refrigerants viz., air, CO2, NH3, etc. Besides, efforts are being directed to develop other types of refrigeration technologies e.g., magnetic refrigeration,
thermoelectric refrigeration (discussed in Part 1) and thermoacoustic refrigeration (discussed in Part 2), which will be moreecofriendly, cost effective, efficient, simple in design, convenient and reliable. 相似文献
78.
Commentary on Cross‐Cultural Perspectives on Positive Youth Development With Implications for Intervention Research
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There is a growing focus on youth positive development issues among researchers and practitioners around the world. In this special issue of Child Development, each of the international authors provides new perspectives and understanding about youth developmental assets in different cultural settings. The present commentary (a) examines some of the cross‐cultural themes that emerge from the four articles by international authors in this issue with implications for positive youth development (PYD) and (b) how intervention science can benefit by incorporating a PYD approach. As evident, youth involved in contexts that provide positive resources from significant others not only were less likely to exhibit negative outcomes, but also were more likely to show evidence of positive development. 相似文献
79.
80.