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11.
We extended an improved version of the discrete particle swarm optimization (DPSO) algorithm proposed by Liao et al.(2007) to solve the dynamic facility layout problem (DFLP). A computational study was performed with the existing heuristic algorithms, including the dynamic programming (DP), genetic algorithm (GA), simulated annealing (SA), hybrid ant system (HAS), hybrid simulated annealing (SA-EG), hybrid genetic algorithms (NLGA and CONGA). The proposed DPSO algorithm, SA, HAS, GA, DP, SA-EG, NLGA, and CONGA obtained the best solutions for 33, 24, 20, 10, 12, 20, 5, and 2 of the 48 problems from (Balakrishnan and Cheng, 2000), respectively. These results show that the DPSO is very effective in dealing with the DFLP. The extended DPSO also has very good computational efficiency when the problem size increases.  相似文献   
12.
Eye injuries from blunt forces and penetrating objects can cause morbidity, disability, and blindness. Most of these injuries are preventable not only by understanding the detail of injury, but also by portraying the role of the ball’s characteristics. Basketball can induce severe forms of injuries to the eye. This study was aimed at performing a numerical analysis through the fluid–structure interaction on ocular trauma. Balls with different diameters, elastic moduli, and pressures were shot to the eye. Injury in terms of the stresses and deformations in each component of the eye was computed at ~?0.72 mm deformation in the apex of the cornea. By increasing the diameter of the ball from 20 to 26 cm the stress in the eye components, excluding the aqueous body, vitreous body, and extraconal fat, increased. Stresses of 2.68 and 3.19 MPa were observed in the cornea under the ball diameters of 20 and 26 cm, respectively. Conversely, the elastic modulus and pressure of the ball in the defined range showed no considerable role on the stress in the eye components. The results revealed the importance of the ball size compared to the elastic modulus and pressure in the stress accumulation as a result of ocular trauma.  相似文献   
13.
Despite the significant role of oral presentation in the academic context, many university students evade opportunities for participation due to low self-efficacy. The present study has been conducted to compare oral presentation self-efficacy of English as a Foreign Language (EFL) learners with undergraduates and postgraduates of Non-EFL majors, and to investigate the relationship of this construct with their teaching and prior academic oral presentation experiences as two modes of Bandura’s [(1995). Exercise of personal and collective efficacy in changing societies. In A. Bandura (Ed.), Self-efficacy in changing societies (pp. 1–45). New York: Cambridge University Press] mastery experience. Extracting the oral presentation sub-skills from the literature, an oral presentation self-efficacy questionnaire with 38 five-Likert scale items was constructed. A two-way between-group ANOVA was run on the responses of a total 48 postgraduates (25 EFL and 23 Non-EFL) and 63 undergraduates (28 EFL and 35 Non-EFL) selected randomly from two of the universities in Iran. The results indicated no difference between EFL and Non-EFL students, whether at undergraduate or postgraduate level, in terms of their oral presentation self-efficacy. Spearman’s correlation coefficient, however, showed a strong positive correlation between the two modes of mastery experience and oral presentation self-efficacy (r?=?.44, n?=?111, P?r?=?.42, n?=?111, P?相似文献   
14.
A comprehensive numerical study was conducted to investigate heat transfer enhancement during the melting process in a 2D square cavity through dispersion of nanoparticles. A paraffin-based nanofluid containing various volume fractions of Cu was applied. The governing equations were solved on a non-uniform mesh using a pressure-based finite volume method with an enthalpy porosity technique to trace the solid-liquid interface. The effects of nanoparticle dispersion in a pure fluid and of some significant parameters, namely nanoparticle volume fraction, cavity size and hot wall temperature, on the fluid flow, heat transfer features and melting time were studied. The results are presented in terms of temperature and velocity profiles, streamlines, isotherms, moving interface position, solid fraction and dimensionless heat flux. The suspended nanoparticles caused an increase in thermal conductivity of nano-enhanced phase change material (NEPCM) compared to conventional PCM, resulting in heat transfer enhancement and a higher melting rate. In addition, the nanofluid heat transfer rate increased and the melting time decreased as the volume fraction of nanoparticles increased. The higher temperature difference between the melting temperature and the hot wall temperature expedited the melting process of NEPCM.  相似文献   
15.
Emulsion polymerization was used to synthesize poly butyl cyanoacrylate nanoparticles in presence of steric stabilizer dextran 70. Nanoparticles were characterized by particle size analysis, scanning electron microscopy and light microscopy. Polymerization factors affecting particle size and distribution such as dextran 70, polysorbate 80 (PS 80) and H+ concentration, polymerization time and temperature, and sonication were studied. Distinct concentrations of stabilizer were needed to produce proper nanoparticles. In this case, the appropriate value was 2 % of total volume. At pH 4 significant decrease in production efficiency demonstrated the substantial effect of H+ concentration on nanoparticles. Furthermore significant increases in particle size and distribution was observed at 50 °C compared to room temperature. 0.001 % (v/v) PS 80 represented notable influence on size and distribution. In addition, shaped nanoparticles were obtained by altering polymerization time from 5.5 h to 18 h. Finally, nanoparticle features were influenced by different factors. Appropriate manipulating of such factors can lead to obtaining desirable nanoparticles.  相似文献   
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17.
This study is aimed to investigate the nanoliposomal artemisinin preparation, and its implementation on breast cancer cells. Side effects have been one of the common challenges of drug usage, as well as cancer treatment. In order to reduce such effects, nanotechnology has been a great help. Nanoliposomes are provided through reverse phase evaporation. In this method, certain proportions of phosphatidylcholine, cholesterol and artemisinin were mixed together. Besides, the obtained formulation was pegylated by using polyethylene glycol 2000 in order to increase its stability and solubility. The mean diameter of non-pegylated and pegylated liposomal artemisinin was determined by Zeta sizer system. The percent of drug released from liposome was performed by dialysis. The encapsulation efficiency of both formulations was estimated by spectrophotometry method. As a result, encapsulation and drug release of nanoliposomal formulation were more than the pegylation of the same formulation. In addition, this study indicated that cytotoxicity effect of pegylated nanoliposomal artemisinin was more, in comparison with nanoliposomal artemisinin.  相似文献   
18.
It is clear that cancer is one of the most mortal diseases in the world and the most prevalent among women is breast cancer. As hydroxyurea (HU)—a drug which is used in chemotherapy—has many adverse effects in long-term despite of its therapeutic properties, we made use of nano drug delivery technology in order to reduce adverse effects and increase therapeutic index. Thus, liposomation is a novel way in drug delivery systems. In this study a mixture of phosphatidylcholine and cholesterol was mixed and HU was added to the resultant mixture. The mean diameter of the nanoliposomal HU measured with the Zeta Sizer device (equal to 402.5 nm) and its encapsulation efficiency was 70.8 %. Besides, using dialysis, the pattern of drug release from nanoliposomes has been studied and the results showed that the drug release of nanoliposomal drug within 28 h was equal to 25.85 %. This study showed that the cytotoxicity effect of nanoliposomal drug is more than that of the standard drug.  相似文献   
19.
Bug reports are an essential part of a software project's life cycle since resolving them improves the project's quality. When a new bug report is received, developers usually need to reproduce the bug and perform code review to locate the bug and assign it to be fixed. However, the huge number of bug reports and the increasing size of software projects make this process tedious and time-consuming. To solve this issue, bug localization techniques try to rank all the source files of a project with respect to how likely they are to contain a bug. This process reduces the search space of source files and helps developers to find relevant source files quicker. In this paper, we propose a multi-component bug localization approach that leverages different textual properties of bug reports and source files as well as the relations between previously fixed bug reports and a newly received one. Our approach uses information retrieval, textual matching, stack trace analysis, and multi-label classification to improve the performance of bug localization. We evaluate the performance of the proposed approach on three open source software projects (i.e., AspectJ, SWT, and ZXing) and the results show that it can rank appropriate source files for more than 52% of bugs by recommending only one source file and 78% by recommending ten files. It also improves the MRR and MAP values compared to several existing state-of-the-art bug localization approaches.  相似文献   
20.
Breast cancer is one of the most frequent cancer types within women population. Hydroxyurea (HU) is a chemotherapy compound for treatment of patients with cancer diagnosis, including breast cancer associated with several adverse effects. In this study, we applied nanotechnology to decreased drug side effects along with improvement of therapeutic index. Liposomation is widely used in modern pharmacological developments in order to enhance the effects of the drugs. To achieve this, in this study a mixture of phosphatidylcholine and cholesterol was made up and HU was added to the resultant mixture, was then pegylated using Polyethylene Glycol 2000 to increase resistance, applicability and solubility. The mean diameters of nanoliposomal and pegylated nanoliposomal HU were measured by Zeta sizer device and obtained about 402.5 and 338.2 nm. The efficiency of non-pegylated and pegylated liposomal HU was 70.8 and 64.2, respectively. Releasing HU in both formulations was estimated about 25.8 and 21.7 %. Also, this study investigated the cytotoxicity effect of nanoliposomal and pegylated nanoliposomal HU using MTT assay. Results of this investigation showed that the cytotoxic properties of pegylated HU was 3.6 % more than those non-pegylated form, while was 38.93 % more than ordinary from of HU. This study showed that the stability, releasing pattern and cytotoxicity of the pegylated nanoliposomal HU is better than that of nanoliposomal HU.  相似文献   
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