Trial with an antiprogestin for the termination of early pregnancy and its biochemical effects     

R. K. Mittal  Archana Baghel  Anjali Chakraborty  R. Baveja 《Indian journal of clinical biochemistry : IJCB》1989,4(1):65-69

A clinical study was carried out on an antiprogestin, a synthetic steroid, 17 Hyroxy-11 β-(4-dimethyl amino-phenyl-1)—17 (Prop-1-ynyl-estra—4, 9, dien-3-one) for the termination of pregnancies in female subjects within 14 days of missed menstrual period and with positive urine pregnancy test (Gravindex Test). The compound was tested for its efficacy as an abortifacient and its acceptance by human subjects was assessed by measuring various biochemical parameters before and after introduction of the drug. The parameters measured in the subjects included, fasting blood sugar, blood urea, SGOT, SGPT, serum alkaline phosphatase, serum bilirubin, serum creatinine, serum proteins, A/G ratio and serum Na⁺, K⁺. Statistically insignificant variation was noted in all the parameters studied. This clearly shows that the drug is very well accepted by human subjects. 70% of the subjects tested in the pilot study aborted within 4 days of introduction of the drug. Overall, 90% of the subjects tested aborted as a result of introduction of the drug.  相似文献   

Markov Chain Monte Carlo     

Arnab Chakraborty 《Resonance》2002,7(5):66-75

We describe the mathematics behind the Markov Chain Monte Carlo method of simulation.  相似文献   

Hereditary methaemoglobinaemia due to Cytochrome b-5 reductase deficiency—A case report     

U. K. Saha  I. Chakraborty  S. Ghosh  P. Banerjee  A. K. Chakrabarti 《Indian journal of clinical biochemistry : IJCB》1997,12(2):146-147

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Dissipation of pencycuron in rice plant     

Pal R  Chakrabarti K  Chakraborty A  Chowdhury A 《Journal of Zhejiang University. Science. B》2005,6(8):756-758

INTRODUCTION Pencycuron [1-(4-chlorobenzyl)-1-cyclopentyl- 3-phenylurea], a relatively new non-systemic protec-tive fungicide for controlling sheath blight (Rhizoc-tonia solani) of rice (Sylvanie and Cornis, 1989; Tomlin, 1997), is expected to be used widely in ag-ricultural production particularly in Asia. However, information on the dissipation pattern of pencycuron in rice plant is lacking. Little information on the en-vironmental fate of pencycuron has been published although there …  相似文献   

Evaluation of a rime-based reading program with Shuswap and Heiltsuk First Nations prereaders     

Walton  Partrick D.  Bowden  Michael E.  Kurtz  Shelly L.  Angus  Mary 《Reading and writing》2001,14(3-4):229-264

The utility of teaching reading using rime-based readingstrategies with prereaders was examined. Two experiments are presentedthat studied the effects of a rime-based reading program with FirstNations prereaders; one experiment with Shuswap kindergartners andthe other with Heiltsuk Grade 1 children. Rhyming, phoneme identity,letter-sound knowledge, phonological working memory, First Nationslanguage speaking ability, and reading were measured. In the Shuswapgroup, the reading program increased the abilities that werespecifically taught, rhyming, initial phoneme identity, letter-sounds,and word reading by rime-analogy, compared to the control group.Children also developed abilities that were not specifically taught,final phoneme identity and reading by letter recoding, and could use therime-analogy strategy to read words with unfamiliar rime endings.Phonological working memory remained unchanged. The Heiltsuk childrengained in reading compared to a Grade 1 comparison group. Pretestletter-sound knowledge and rhyming were related to later reading butphoneme identity and First Nations language ability were not. Progressin phonological awareness and word reading can be enhanced in prereadersby adding experience with rime-based strategies to the readingprogram.  相似文献   

Advocating for controversial issues: The effect of activism on compliance‐gaining strategy likelihood of use     

Kenzie A. Cameron  Shelly Campo  Dominique Brossard 《Communication Studies》2013,64(3):265-281

Previous research has demonstrated that compliance‐gaining strategies can he arrayed on an unidimensional continuum, anchored by positive, pro‐social strategies and negative, antisocial strategies (Hunter & Boster, 1987; Rolojf & Barnicott, 1978, 1979). Individual differences, including argumentativeness and verbal aggression (Boster & Levine, 1988), have been shown to affect one's ethical threshold. This ethical threshold is consistent with a Guttman simplex and determines both how many, as well as how antisocial, compliance‐gaining strategies individuals may consider using. Activists, who are highly involved and committed to their cause and who tend to be less verbally aggressive and more argumentative than the general public (Campo, 1999), are likely to have a lower threshold and to use more strategies. This study examines to what extent activism predicts one's ethical threshold, when controlling for the known effects of argumentativeness, verbal aggressiveness, and sex. Participants (N = 454) at two separate universities completed a repeated measures questionnaire that asked them to indicate their likelihood of use of 25 separate compliance‐gaining strategies. Based on respondents’ likelihood of use of these 25 strategies, the data were consistent with a Guttman simplex. A multiple regression model was tested, and indicated that one's ethical threshold is directly predicted by level of activism and verbal aggressiveness. Sex and argumentativeness were not found to be significant predictors in this revised model. In addition, activists used more strategies than non‐activists. Implications for advancing research related to activism and compliance‐gaining strategy selection are discussed.  相似文献   

Preface to Special Topic: Microfluidics in Cancer Research     

Suman Chakraborty 《Biomicrofluidics》2013,7(1)

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A closer look at the Mulliken-Barker test     

Kaushik Basu  Suchandra Chakraborty  Chandan Saha 《Resonance》2013,18(9):845-848

Qualitative analysis of unknown organic compounds is an essential part of the core curriculum for BSc and MSc students in chemistry. The functional group detection is a significant component of qualitative analysis. The present work describes the reason for the failure of Mulliken-Barker test for nitro compounds having carboxylic acid functionality and suggests a possible remedy.  相似文献   

THE GROWTH AND RESOURCES OF TRAINING SCHOOLS     

J. Shelly Meyer 《Religious education (Chicago, Ill.)》2013,108(5):550-555

Teachers are thought to be the backbone of any high school. Data indicating how students perceive their teachers was gathered from a questionnaire completed by 355 recent Yeshiva high-school graduates. Results show that Yeshiva High School teachers are thought of as open minded and tolerant (51.9%), caring (73.2%), and interested in developing the teacher/student relationship (77.2%). The 66% of Yeshiva students who viewed teachers as positive role models stood in sharp contrast to the 2.4% of the general high-school population reported in the literature who viewed teachers as positive role models.  相似文献   

Study of oxidative stress in obsessive compulsive disorder in response to treatment with Fluoxetine     

Sutirtha Chakraborty  Anindya Dasgupta  Harendra Nath Das  Om Prakash Singh  Asok Kumar Mandal  Nikhiles Mandal 《Indian journal of clinical biochemistry : IJCB》2009,24(2):194-197

Oxidative stress has been found to play important role in several neuropsychiatric diseases including Obsessive Compulsive Disorder. A longitudinal case control study was conducted to evaluate the oxidative stress in 30 newly diagnosed obsessive compulsive disorder patients and same number of control patients. Serum thiobarbituric acid reacting substances, plasma ascorbate were assessed to evaluate oxidative stress and Yale Brown obsessive compulsive scale for disease severity before and after treatment with Fluoxetine at the average dosage of 40 mg/day. Improvement in Yale Brown obsessive compulsive scale score by about 43% after 12 weeks treatment was associated with significantly decreased thiobarbituric acid reacting substances and increased plasma ascorbate values (p < 0.05). The newly diagnosed obsessive compulsive disorder patients had higher serum thiobarbituric acid reacting substances as well as a lower plasma ascorbate levels than the control population. Thus, the present study suggested a significant role of oxidative stress in obsessive compulsive disorder and showed that a successful treatment with Fluoxetine not only improves the clinical scenario but also reduces the oxidative stress that may further improve the prognosis of the disease.  相似文献