Validation of two accelerometers to determine mechanical loading of physical activities in children     

Ursina Meyer  Dominique Ernst  Silvia Schott  Claudia Riera  Jan Hattendorf  Jacqueline Romkes 《Journal of sports sciences》2015,33(16):1702-1709

The purpose of this study was to assess the validity of accelerometers using force plates (i.e., ground reaction force (GRF)) during the performance of different tasks of daily physical activity in children. Thirteen children (10.1 (range 5.4–15.7) years, 3 girls) wore two accelerometers (ActiGraph GT3X+ (ACT), GENEA (GEN)) at the hip that provide raw acceleration signals at 100 Hz. Participants completed different tasks (walking, jogging, running, landings from boxes of different height, rope skipping, dancing) on a force plate. GRF was collected for one step per trial (10 trials) for ambulatory movements and for all landings (10 trials), rope skips and dance procedures. Accelerometer outputs as peak loading (g) per activity were averaged. ANOVA, correlation analyses and Bland–Altman plots were computed to determine validity of accelerometers using GRF. There was a main effect of task with increasing acceleration values in tasks with increasing locomotion speed and landing height (P < 0.001). Data from ACT and GEN correlated with GRF (r = 0.90 and 0.89, respectively) and between each other (r = 0.98), but both accelerometers consistently overestimated GRF. The new generation of accelerometer models that allow raw signal detection are reasonably accurate to measure impact loading of bone in children, although they systematically overestimate GRF.  相似文献   

Language and reading impairments are associated with increased prevalence of non-right-handedness     

Filippo Abbondanza  Philip S. Dale  Carol A. Wang  Marianna E. Hayiou-Thomas  Umar Toseeb  Tanner S. Koomar  Karen G. Wigg  Yu Feng  Kaitlyn M. Price  Elizabeth N. Kerr  Sharon L. Guger  Maureen W. Lovett  Lisa J. Strug  Elsje van Bergen  Conor V. Dolan  J. Bruce Tomblin  Kristina Moll  Gerd Schulte-Körne  Nina Neuhoff  Andreas Warnke  Simon E. Fisher  Cathy L. Barr  Jacob J. Michaelson  Dorret I. Boomsma  Margaret J. Snowling  Charles Hulme  Andrew J. O. Whitehouse  Craig E. Pennell  Dianne F. Newbury  John Stein  Joel B. Talcott  Dorothy V. M. Bishop  Silvia Paracchini 《Child development》2023,94(4):970-984

Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta-analysis (N_cases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.  相似文献   

A deep vein thrombosis caused by 20209C>T mutation in homozygosis of the prothrombin gene in a Caucasian patient     

Silvia Izquierdo álvarez  Eva Barrio Ollero  Francisco Miguel Llinares Sanjuan  Fabiola Lorente Martínez  María Teresa Calvo Martín 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(1):159-166

Introduction:

Additional nucleotide substitutions in the 3′-untranslated region of prothrombin gene could explain some thrombotic events and also adverse pregnancy outcomes. We describe the first case of a homozygous 20209C>T mutation as the cause of deep vein thrombosis in a Spanish patient.

Case and methods:

The 56-year-old male patient with a partial tear of the Achilles tendon developed calf (tibial) deep vein thrombosis after immobilization and was treated with an anticoagulant. To determine if the deep vein thrombosis was of genetic origin, a peripheral blood DNA sample was analysed for the presence of the three most frequent mutations associated with thrombotic events: factor V Leiden (1691G>A), prothrombin (20210G>A) and methylene tetrahydrofolate reductase (677C>T). The presence or absence of the normal allele of prothrombin could not be determined using the PTH-FV-MTHFR StripAssay (Vienna Lab).

Results:

Comprehensive analysis showed that the patient had a variant interfering with the polymerase chain reaction product, we sequenced the entire prothrombin gene and found that the patient had a homozygous C>T mutation at position 20209; this interfered with the polymerase chain reaction product, which needs a C at this position to be able to bind to the wild-type probe present in the test strip.

Conclusion:

The homozygous 20209C>T mutation and the presence of the mutation 677C>T in heterozygosity explained the patient’s deep vein thrombosis because the combination of mutations would increase the risk of thrombosis. Suitable genetic counselling should be provided to the patient and first-degree relatives as it important to detect prothrombin gene variants that could increase risk for thrombotic events.  相似文献   

Book reviews     

Czesŀaw Kupisiewicz  J. A. Majasan  Silvia Mercedes Guruni  Abdul Quadir Yousuf 《Prospects》1975,5(4):533-545

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比较图书馆学:一门理论学科     

西尔维娅·西姆索娃  肖力 《大学图书馆学报》1990,(1):51-57

<正> 十九世纪中叶,爱德华·爱德华兹以翔实的欧洲各国的图书馆调查资料为素材,写成了《英国公共图书馆立法概论》一文,于是,他在无意间首次涉足比较图书馆学研究领域,只是他自己当时浑然不觉。从那时起至本世纪中叶,即爱德华兹发表论文后整整一百年,英语词汇中才出现了“比较图书馆学”一词。1966年,比较图书馆学才作为必修课程被纳入有关图书馆学正式课表中。自此,我一直从事本课程的教学。因此在撰写本论文时,我将以一个最早、并长期从事比较图书馆学教育工作的教师,而不是一个从事实验工作的图书馆员的观点来看待并阐述问题。在我们专业领域里,不少刊物发表了对图书馆学定义的论文。多数作者都提出其各自的定义。定义种类繁多,相互矛盾,观点相左(所有关于比较图书馆学定义的讨论文章可见新  相似文献   

Innovators and imitators: Organizational reference groups and adoption of organizational routines   总被引：3，自引：0，他引：3  

Silvia Massini  Arie Y. Lewin  Henrich R. Greve   《Research Policy》2005,34(10):1550-1569

Firms vary greatly in their rates of creating and adopting technological and organizational innovations, in part because of their choice of reference group. We argue that the selection of a reference group is a crucial and neglected source of firm heterogeneity. Comparisons to the average of other firms in a population cause most firms to adopt innovations once they are widely accepted. A distinctive feature of the minority of innovating firms that create innovations or adopt them early is that they compare themselves with, compete with, and try to differ from other innovating firms, whereas the majority of firms compare themselves with, and conform to, a broader group of firms. We elaborate this argument based on the behavioral theory of the firm and institutional theory, and test it on a two-period survey on adoptions of innovative organizational forms in Europe and the US. The analysis shows the predicted differences in the adoption patterns of innovating and imitating firms.  相似文献   

Socio-cultural variation in reading comprehension development among fifth graders in Peru     

Silvia Morales Silva  Ludo Verhoeven  Jan van Leeuwe 《Reading and writing》2011,24(8):951-969

In this study, the socio-cultural variation in reading comprehension development was examined in 331 fifth graders from schools in Lima, Peru. Reading comprehension was measured using an adaptation of the PIRLS Reading Literacy test. The fifth graders?? reading comprehension results, measured over the course of fifth grade, were related to the development of word decoding, vocabulary, and motivation for reading. Children??s development in these domains was related to their gender, intellectual maturity, home literacy climate, and socio-economic status. Structural Equation Modelling showed that the development of reading comprehension was influenced by the children??s ability to decode words, their vocabulary, and reading motivation. Furthermore, gender and intellectual maturity as well as children??s home literacy climate and socio-economic status appeared to substantially predict reading comprehension development, directly or indirectly. More than half of the variance in reading comprehension by the end of the fifth grade could be explained based on these predictor variables.  相似文献   

Evaluating the reflexive practices in a learning experience     

Andreina Bruno  Laura Galuppo  Silvia Gilardi 《European Journal of Psychology of Education - EJPE》2011,26(4):527-543

Reflexivity is a primary requirement for professional work. Our aim was to describe a methodology suitable for detecting the development of reflexive practice through the analysis of 59 Master’s degree students’ journals. We explore the use and changes of reflexive practice in relation to the settings and activities of the course using analysis of the mental language: We analyse how the reflexive practice is characterized, how it evolves through time and how it can be promoted. Data analysis shows that reflexivity is not monodimensional but multidimensional. Reflexive practice increases during the course: The different dimensions vary over time according to different organizational and educational conditions. This methodology allows us to formulate new hypotheses about which elements of the setting and process are effective in supporting participants’ reflexive practice.  相似文献   

Scaling up comprehensive sexuality education in Nigeria: from national policy to nationwide application     

Silvia Huaynoca  Venkatraman Chandra-Mouli  Nuhu Yaqub Jr.  Donna Marie Denno 《Sex education》2014,14(2):191-209

Nigeria is one of few countries that reports having translated national policies on school-based comprehensive sexuality education (CSE) into near-nationwide implementation. We analysed data using the World Health Organization-ExpandNet framework, which provides a systematic structure for planning and managing the scaling up of health innovations. We examined how Nigeria's nationwide programme was designed and executed. Since 2002, Nigeria has developed a well thought through strategy to scale up CSE. Crucial attributes that facilitated the scaling up included technical consensus about the innovation and clarity about its components, dissection of a complex intervention into manageable components for implementation by organisations with complementary expertise, strong political leadership and championship in concert with advocacy and technical support from non-governmental organisations, proactive and energetic involvement of community stakeholders, effective programme management, and improvements to the information management system to ensure on-track implementation and mid-course corrections to keep stakeholders, including funders, informed and engaged. Challenges included programmatic values, competing priorities for available human resources and a lack of predictable funding for sustaining a rapid scale-up effort. Despite some weaknesses, implementation has largely proceeded according to plan. The lessons learned from Nigeria's experience can and should be used in other settings to achieve wide-scale coverage.  相似文献   

Searching for blood in Chinese lacquerware     

Silvia Miklin-Kniefacz  Martina Griesser  Walther Parson  Václav Pitthard  Sabine Stanek 《文物保护研究》2014,59(5):S252-S253

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