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11.
Research on the development of metamemory has focused primarily on children's understanding of the variables that influence how likely a person is to remember something. But metamemory also involves an understanding of why people occasionally misremember things. In this study, 5- and 6-year-olds ( N  =   38) were asked to decide whether another child's mistakes in a memory game were due to false memories or guesses. Some of the fictitious child's mistakes were similar to material he had seen earlier and some were not. Six-year-olds, but not 5-year-olds, consistently attributed more similar than dissimilar mistakes to false memories. Understanding the link between similarity and false memories improves significantly between 5 and 6 years of age.  相似文献   
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Can young children visualize the solution to a difficult spatial problem? Forty‐eight 3‐year‐olds were tested in a spatial reasoning paradigm in which they were asked to predict the path of a ball moving through 1 of 3 intertwined tubes. One group of children was asked to visualize the ball rolling down the tube before they made their predictions, a second group was given identical instructions without being asked to use visual imagery, and a third group was given no instructions. Children in the visualization condition performed significantly better than those in the other conditions, suggesting that encouraging young children to use visual imagery may help them to reason through difficult problems.  相似文献   
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Stroke is the third major cause of death and foremost cause of disability worldwide. Cerebrovascular stroke remains largely a clinical diagnosis. The use of biomarkers in diagnosing stroke and assessing prognosis is an emerging and rapidly evolving field. The study aimed to investigate the predictive value of neurobiochemical marker of brain damage (neuron-specific enolase [NSE]) with respect to degree of disability at the time of admission and neurological worsening in acute ischemic stroke patients. We investigated 150 patients with cerebrovascular stroke who were admitted within 72 h of onset of stroke in the Department of Neurology at SAIMS. Venous blood samples were taken after admission and NSE was analyzed by solid enzyme linked immunosorbent assay using Analyzer and microplate reader from Biored: Code 680. In all patients, the neurological status was evaluated by a standardized neurological examination and the National Institutes of Health Stroke Scale on admission and on day 7. Serum NSE concentration was found to significantly correlate with both degree of disability and neurological worsening in acute ischemic stroke cases in the present study. The maximum serum NSE level within 72 h of admission was significantly higher in patients with greater degree of disability at the time of admission. Serum NSE levels were also found to be significantly elevated in patients with bad neurological outcome. Our study showed that serum NSE has high predictive value for determining severity and early neurobehavioral outcome after acute stroke.  相似文献   
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Jaswal VK 《Child development》2004,75(6):1871-1885
A label can convey nonobvious information about category membership. Three studies show that preschoolers (N=144) sometimes ignore or reject labels that conflict with appearance, particularly when they are uncertain that the speaker meant to use those labels. In Study 1, 4-year-olds were more reluctant than 3-year-olds to accept that, for example, a cat-like animal was a dog just on the basis of hearing it called a dog. In Studies 2 and 3, this reluctance was overcome when the speaker explicitly or implicitly indicated that use of the unexpected labels was intentional. These studies demonstrate that preschoolers do not treat labels as atheoretical features of objects; rather, they interpret them in light of their understanding of the labeler's communicative intent.  相似文献   
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Computer Assisted Learning (CAL) is increasingly being recognised as an effective means of teaching and learning. In Gynaecology, the anatomy and surgical steps in vaginal surgery such as vaginal hysterectomy are confusing due to limited access and restricted view of the operative field. The objective of this pilot project was to develop an interactive CAL program on CD–ROM, combining video, illustrations and three–dimensional images to enhance understanding of vaginal hysterectomy in terms of the anatomy and steps of the surgical procedure.
Macromedia Director was used to develop the program. With Director, it is possible to combine text, graphics, animation, video and sound to create interactive material for the web, presentations or CD–ROMS. The CD–ROM takes you through the individual steps of a vaginal hysterectomy combining video clips with voice–over, illustrations and text. The three-dimensional image was included to enhance understanding of the complex relationships between the uterus, bladder and rectum. There is an interactive self–assessment section with multiple–choice questions and an anatomy self–test. The CD–ROM has been evaluated as an educational tool by 12 undergraduate students and 16 trainees in Gynaecology. Most were satisfied with the program. A need for development of further similar educational software has been identified.
The CD–ROM has identified an innovative and useful approach to teaching operative surgery. The results from the evaluation have been positive in terms of the need for similar programs in future.  相似文献   
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Do children expect an expert in one domain to also be an expert in an unrelated domain? In Study 1, 32 three‐ and four‐year‐olds learned that one informant was an expert about dogs relative to another informant. When presented with pictures of new dogs or of artifacts, children who could remember which informant was the dog expert preferred her over the novice as an informant about the names of dogs, but they had no preference when the informants presented artifact labels. In Study 2, 32 children learned that one informant was incompetent about dogs whereas another was neutral. In this case, children preferred the neutral speaker over the incompetent one about both dogs and artifacts. Taken together, these results suggest that for children, expertise is not subject to a “halo effect,” but incompetence may be subject to a “pitchfork effect.”  相似文献   
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Microalbuminuria is an established cardiovascular risk indicator in diabetes, hypertension and the general population. There is lack of information on MAU in healthy obese Indian adults and an ongoing debate whether obese adults deserve targeted identification and clinical intervention for MAU and prediabetes. We aimed to screen the healthy obese, young (group I) and middle aged (group II) adults for prevalence of MAU and prediabetes and study its association with Framingham risk score. The study included 50 healthy obese young (20–30 years) and middle aged adults (31–50 years), attending the outpatient clinic of Dept. of Medicine for a duration of 2 months (July–August). The patients were screened for fasting blood sugar, lipid profile and MAU. Of the total patients 28 % had MAU, 32.14 % of which had prediabetes and 33.33 % had diabetes whereas 10 % were normoglycemic. The group I patients had 50 % cases of MAU and group II had 25 % patients with MAU. Group II 63.63 % pre-diabetics. The values of MAU obtained were correlated with age, gender, body mass index, systolic and diastolic blood pressure, FBS, waist to hip ratio using Pearson’s Coefficient (p < 0.05). The 10 year CVD risk calculated using FRS in subjects with MAU was higher as compared to those without MAU. Thus we conclude that Indian, young and middle aged obese adults to be at a risk of prediabetes, MAU and CV risk warranting their routine screening for better clinical outcomes.  相似文献   
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Identification of reliable biomarkers for detection and staging of cancer and monitoring the outcome of anticancer therapy has been considered to be of high importance. We aimed to estimate the levels of serum glycoproteins, protein bound-hexose, protein bound hexosamine, protein bound fucose, protein bound sialic acid and protein bound carbohydrate in 32 ovarian cancer patients and compared them with the levels that found in 25 normal subjects. As compared to the normal subjects, all the four fractions of glycoproteins level were significantly elevated in ovarian cancer patients (p < 0.05). Chemotherapy in these patients significantly decreased the levels of serum glycoproteins (p < 0.05). Thus, high levels of serum glycoproteins in ovarian cancer patients could be due to abnormal protein glycosylation indicating malignant transformation of the cells.  相似文献   
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