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101.
Radical, breakthrough innovations create not only great industrial possibilities, but also great social uncertainties. When a breakthrough medical technology is discovered, the question arises as to whether to accept the possible risks involved, or to defer implementing the innovation until more data is available, and, specifically, until others have taken up the innovation and demonstrated both its efficacy, its relative safety and market acceptance. Specifically, when a firm discovers a new candidate substance for a first in its class drug, how to evaluate the potential risks becomes a key predicament for management. This paper focuses on the role of a firm's social networks and national innovation system context in influencing the social epistemology around potential breakthrough innovations. Through an examination of the processes of drug development related to the same candidate substance in a Japanese firm and an American firm, we suggest that, in addition to organizational capabilities at the corporate level, social capital, specifically formed under a certain innovation system, plays a key role in leading to the successful introduction of breakthrough innovations.  相似文献   
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Book reviews     
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In most existing art museum Web pages, the values of the museum dominate the values of the Web. Therefore, museum Web pages often electronically duplicate familiar museum products – floor plans, collection catalogues, event calendars – rather than transforming the idea of the museum by adapting the values of the Web.This paper will seek to show how art museums and technologists can come to understand each other and use their differences productively by:1. Orienting museum Web sites towards projects that can only be done on the Web and not on paper.2. Using the Web to overcome the many limitations to understanding imposed by the physical art museum.3. Using the interactive potentials of the Web to change the one-way flow of information from art museum to visitor to a two-way flow which also moves from visitor to museum.4. Infusing the orientation towards constant change into the art museum so that the Web helps the art museum to reinvent itself.  相似文献   
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Research on teaching and learning in condensed-course formats is varied and difficult to generalize. We analyze this research and identify factors that may account for the varied findings. Additionally, we present a mixed methodology study of 20 matched-pair courses (i.e., full and condensed formats) from 11 disciplines which examines student learning and student and faculty perception data. We find that faculty and students perceive condensed courses as more effective, but that student learning varies depending upon the measures used to assess it. We conclude by considering the implications of our study for teaching and assessment practices.  相似文献   
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OBJECTIVE: This study examined the relationship between reported exposure to child abuse and a history of parental substance abuse (alcohol and drugs) in a community sample in Ontario, Canada. METHOD: The sample consisted of 8472 respondents to the Ontario Mental Health Supplement (OHSUP), a comprehensive population survey of mental health. The association of self-reported retrospective childhood physical and sexual abuse and parental histories of drug or alcohol abuse was examined. RESULTS: Rates of physical and sexual abuse were significantly higher, with a more than twofold increased risk among those reporting parental substance abuse histories. The rates were not significantly different between type or severity of abuse. Successively increasing rates of abuse were found for those respondents who reported that their fathers, mothers or both parents had substance abuse problems; this risk was significantly elevated for both parents compared to father only with substance abuse problem. CONCLUSIONS: Parental substance abuse is associated with a more than twofold increase in the risk of exposure to both childhood physical and sexual abuse. While the mechanism for this association remains unclear, agencies involved in child protection or in treatment of parents with substance abuse problems must be cognizant of this relationship and focus on the development of interventions to serve these families.  相似文献   
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The present study was an attempt to help us reveal the characteristics and complexity of today’s first-time online students in a higher education setting. Data were collected from undergraduate and graduate students enrolled in fully online courses for the first time during spring semester in the 2016–2017 academic year at a Southern university in the United States. Primarily, path analysis was conducted to investigate the impacts of flexible thinking, mindsets, and self-efficacy on the 254 first-time online students’ online learning engagement. The results of the path analysis supported six out of the eight hypotheses and all standardized path coefficients have values between 0.14 and 0.31. In conclusion, growth mindset and learning self-efficacy appear to be important variables for first-time online students and have a positive relation to online engagement. The practical implications and future research are discussed.

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This article makes the argument that the present discourse on developmental appropriateness needs to be expanded. Four points are made: First, the present discourse assumes a consensus about child development that is more apparent than real; second, it is premised on a suspect notion of broad, universal stages; third, it ignores an important alternative perspective to the dominant individualist perspective on learning and development; and fourth, it ignores an important alternative perspective to the dominant view of the relationship between learning and development. Critiques are made and alternative perspectives presented.  相似文献   
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