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11.
Coconut oil has been used by the people of Kerala as a cooking medium for several decades. Due to its alleged hypercholesterolemic activity, general population in recent times is shifting to cooking oils rich in polyunsaturated fats, the most popular being sunflower oil. The effect of long-term consumption of sunflower oil on oxidative stress in humans is not well investigated. We studied oxidative stress among coronary artery disease (CAD) patients who were consuming coconut oil or sunflower oil as a part of their routine diet. Men, aged 35–70 years, with established CAD, who presented to the hospital for routine cardiac evaluations, were enrolled in this observational study. Group 1 and 2 consisted of 73 and 80 subjects consuming coconut oil and sunflower oil respectively for over a period of 2 years. Lipid profile and parameters for oxidative stress were evaluated among them. Conventional lipid parameters did not differ significantly between the two groups. Mean vitamin C concentration was significantly reduced for subjects on sunflower oil compared to those consuming coconut oil (P = 0.044). Malondialdehyde was higher for sunflower oil consumers compared to coconut oil consumers (P < 0.0001). Other parameters such as oxidized LDL, GSH, GPx and SOD were not found to be significantly different between the two groups. The results of the present study show that coconut oil did not induce hypercholesterolemia compared to sunflower oil. On the other hand, sunflower oil group had elevated oxidative stress compared to coconut oil group.  相似文献   
12.
Arsenic contamination of ground water has become a serious problem all over the world. Large number of people from Uttar Pradesh, Bihar and West Bengal of India are suffering due to consumption of arsenic contaminated drinking water. Study was carried out on 30 individuals residing in Ballia District, UP where the maximum concentration of arsenic was observed around 0.37 ppm in drinking water. Blood samples were collected from them to find out the problem related with arsenic. Cytogenetic study of the blood samples indicates that out of 30, two persons developed Klinefelter syndrome.  相似文献   
13.
The development of assessments that are fit to assess professional competence in higher vocational education requires a reconsideration of assessment methods, quality criteria and (self)evaluation. This article examines the self-evaluations of nine courses of a large higher vocational education institute. Per course, 4–11 teachers and 3–10 students participated. The purpose of this article is to critically examine the quality of assessment in higher vocational education, to identify critical factors influencing assessment quality and to study whether self-evaluation leads to concrete points for improvement. Results show that strong points are fitness for purpose, comparability and fairness. Weak points are reproducibility of decisions and development of self-regulated learning. Critical factors are the translation of competences into assessment criteria to be used in daily lessons and the involvement of the work field. The self-evaluations generated many points for improvement, but not all were translated into actions. Altogether, this article provides a rich picture of assessment quality in higher education and identifies quality aspects that need improvement, (partly) confirming other research on current assessment methods.  相似文献   
14.
This study investigated the effectiveness of an instructional program (schema-based instruction, SBI) designed to teach 7th graders how to comprehend and solve proportion problems involving ratios/rates, scale drawings, and percents. The SBI program emphasized the underlying mathematical structure of problems via schematic diagrams, focused on a 4-step procedure to support and monitor problem solving, and addressed the flexible use of alternative solution strategies based on the problem situation. Blocking by teacher at three middle schools, the authors randomly assigned the 21 classrooms to one of two conditions: SBI and control. Classroom teachers provided the instruction. Results of multilevel modeling used to test for treatment effects after accounting for pretests and other characteristics (gender, ethnicity) revealed the direct effects of SBI on mathematical problem solving at posttest. However, the improved problem solving skills were not maintained a month later when SBI was no longer in effect nor did the skills transfer to solving problems in new domain-level content.  相似文献   
15.
In this commentary, I summarize my own research with colleagues to affirm Dr. Gersten's call for considering design experiments prior to conducting intervention research. I describe how design experiments not only can inform teaching and the learning of innovative approaches, but also hold the promise of effectively bridging the research‐to‐practice gap to produce meaningful change in practice when innovative practices are fine‐tuned and validated by partnerships with teacher‐researchers.  相似文献   
16.
The purpose of this article is to describe a collaborative approach to planning in the content areas to include and allow students with learning disabilities access to the general education curriculum. Procedures for selecting and organizing content, determining activities, identifying accommodations and modifications necessary to enhance content learning, and assessing student performance are presented. In addition, a sample unit plan and a lesson plan are included to illustrate the outcomes of collaborative planning based on effective teaching practices.  相似文献   
17.
Jhamarkotra is located a distance of 25 kms from Udaipur city. It has richest deposits of phosphorite ore (Rock phosphate) in our country. The mine has been under operation for the last several years. However, the effect of environmental influence have not been investigated. In the present study water analysis from 8 points of delivery in mine area along with pathological and biochemical parameters is reported. The water is relatively hard and has significantly high content of fluoride and chloride. The miners were divided into four groups on the basis of their exposure in the mining area. The group were; a) non exposed, b) indirectly exposed, c) transiently exposed and d) directly exposed. These were compared with controls. The results indicate that serum uric acid, GPT, alkaline phosphatase level were elevated in directly exposed miners.  相似文献   
18.
Habitual consumption of moderate amounts of fish is associated with reduced mortality from coronary heart disease. However the beneficial effects of fish enriched diet seem contradictory, due to the susceptibility of the PUFAs in them to oxidation. It is also acclaimed that vegetarians in general, have a lower serum total cholesterol and LDL-cholesterol and a better antioxidant status. This contradiction was the basis for the study, where the validity of the above finding was tested in a general population consuming a vegetarian or predominantly fish diet as a regular dietary habit. The oxidant status and the lipid profile of 23 vegetarians and 22 fish eaters was studied by estimating the plasma lipid peroxides measured as malondialdehyde (MDA) and the lipid parameters viz. Total Cholesterol (TC), HDL-Cholesterol (HDL-C) and triglycerides (TG). Statistical analysis was carried out to compare the MDA values and the lipemic status between the two groups. MDA was also correlated with the various lipid indices among the study groups. None of the compared and correlated values was statistically significant, although certain altered trends were seen. From this study, it may be concluded that oxidant status and lipid profile does not vary significantly in the two groups, suggesting that neither a vegetarian diet nor a fish diet has a definite benefit over the other.  相似文献   
19.
Propionic acidemia (PA), an uncommon organic acidemia has varied clinical and metabolic presentation causing difficulty and delay in the diagnosis. We report a case of PA in an infant who presented with failure to thrive, acute encephalopathy due to severe hyperammonemia without acidosis and fungal sepsis. The biochemical basis of severe hyperammonemia is discussed.  相似文献   
20.
Previous research suggests that social–cognitive factors mediate the association between social–environmental risk and aggression in high‐risk samples, but less is known about the relation among these factors in suburban youth. The present study examined whether such an association occurred for suburban youth exposed to low levels of social rejection and community violence. Using data from 184 adolescents (mean age = 14.97 years, SD = .84) and their homeroom teachers, analyses with structural equation modeling revealed a significant relation between relatively mild levels of social–environmental risk and aggression. This association was partially mediated by negatively biased social–cognitive factors (i.e., general knowledge structures and social information processing). Findings suggest that even relatively low levels of social rejection and community violence exposure characterizing suburban youth (in contrast to urban youth) put them at an increased risk for problems with aggression.  相似文献   
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