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The purpose of this study was to determine the effects of short-term normoxic and hypoxic exercise on plasma endothelin-1 and nitric oxide levels, and the relationship of arterial compliance and pulmonary artery pressure to endothelin-1. Seven endurance-trained males completed two incremental and two steady-state exercise tests performed at ventilatory threshold in normoxia and hypoxia (fraction of inspired oxygen = 0.14). Plasma endothelin-1was measured throughout steady-state tests. Arterial compliance using applanation tonometry, plasma nitric oxide and pulmonary artery pressure using Doppler echocardiography were measured before and after exercise. Small arterial compliance and pulmonary artery pressure significantly increased following exercise. There were no main effects of condition or time for plasma endothelin-1and nitric oxide levels. There were no significant relationships between plasma endothelin-1 and arterial compliance or pulmonary artery pressure. In conclusion, mechanisms other than the endothelial system may play a role in the exercise-induced changes in small artery compliance in this study population. Moderate hypoxia and a 30-minute steady-state exercise have limited effects on plasma endothelin-1 in endurance-trained males.  相似文献   
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Recommender systems play an important role in reducing the negative impact of information overload on those websites where users have the possibility of voting for their preferences on items. The most normal technique for dealing with the recommendation mechanism is to use collaborative filtering, in which it is essential to discover the most similar users to whom you desire to make recommendations. The hypothesis of this paper is that the results obtained by applying traditional similarities measures can be improved by taking contextual information, drawn from the entire body of users, and using it to calculate the singularity which exists, for each item, in the votes cast by each pair of users that you wish to compare. As such, the greater the measure of singularity result between the votes cast by two given users, the greater the impact this will have on the similarity. The results, tested on the Movielens, Netflix and FilmAffinity databases, corroborate the excellent behaviour of the singularity measure proposed.  相似文献   
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The painting Proas Iluminadas (Illuminated Bows) by Benito Quinquela Martín is studied by Raman spectroscopy in order to analyse the technique and the pigments employed by the artist: ultramarine blue, carbon black, cadmium-sulphure based compounds for the hue of yellow, orange and red; also zinc white, barium yellow, massicot yellow and viridian were observed. The importance of using different excitation laser lines in the analysis of mixtures of pigments is highlighted. The Raman mapping analysis of cross section samples shows the way the artist composed the ground layer: a lead white stratum over a calcite one. It also allows distinguishing between a mixture of components and strata superposition, both presenting the same appearance under an optical microscope. This paper provides information about the materials and techniques used in a period of Argentine art not studied before from this point of view.  相似文献   
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Nowadays, some virtual museums include 3D room scenes to show the models of its pieces, just like in real museums. Nevertheless, the generation and maintenance of this kind of scenes is generally difficult and should be done by an expert. For example, any change such as including a new piece or modifying the position of an existing fragment usually requires a different design and the creation of a new scene. In this paper we present a case study on the development of a web-based application to automatize this process. To this end, a database to store both graphic and non-graphic information about the pieces, and some 3D rooms to show them has been created. The designed scenes only contain some pieces of furniture to exhibit the fragments, which will be subsequently included. Thus, when a room is loaded in the web page, its associated pieces are obtained through a query in the database and its models are dynamically included in the original scene. Therefore, the position changes or the inclusion of new pieces are not performed in the 3D model, but in the database. Our application makes the transmission of the knowledge to the general public easier because any new discovered piece can be included in a existing museum effortlessly.  相似文献   
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Solihull's development of delegated budgets began in 1981. The experiences of schools and Centre led to the acceptance by Council in 1987 of a scheme for general implementation. The detailed scheme is included in an Appendix to the article, together with examples of vital financial management systems. In his article, the Director of Education explores the effects of delegation of the budget, and with it, the decision‐making process. The school heads’ role gains the natural extension of facility to implement management decisions, but what of the role of the Centre?  相似文献   
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Abstract

Rural landholders are undergoing extended economic hardship, manifested in a range of social and ecological problems that limit the capacity of local areas to recover to economic levels necessary to sustain settlement. The uncertain influence of climate on production represents just one of the range of risk factors that landholders must face. Survival depends on the capacity of landholders to respond strategically to the stress which these risk factors generate. Our research indicates landholders’ capacity to modify land‐management practices, are dictated by their underlying personality traits and by presence or absence of other psychiatric morbidity. Where stresses exist, the capacity of people to respond actively to a planned problem solution diminishes. The psychological profiles of people tend to fall into three groups ‐ those who can generally cope; those who can usually cope but undergo dysfunctional episodes under acute stresses, and those who generally cannot cope.

In the grazing lands of central western Queensland, our findings suggest a predominant personality profile consistent with an ability to cope with isolation and the other particular challenges that characterise this way of life. There are two important implications in these results. The first relates to land stewardship and has significant lessons for government intervention in terms of rural policy and approaches to extension. In particular, there are lessons pertinent to the success of Landcare and associated community based initiatives. The second relates to the broad area of rural health as highlighted by the alarming rates of suicide found in rural Australia. In previous decades, those with personality styles less well‐suited to this industry, found employment in nearby rural towns. This option has declined as government policy has favoured the withdrawal of services and resources, hastening depopulation of rural areas. The resultant weakening of the social fabric of rural society is a cause of tension and stress with serious health implications. Previous approaches to rural sociology have not emphasised individual personality traits in seeking to understand the complexity of the human‐environment relationships which determine land use. Nor has personality been invoked is assessing the potential of landholders to adopt ecologically sustainable practices. Further research is planned to consolidate our findings through comparative investigations in other branches of rural industry. JAgr Educ Ext (2001, 7, 3, pp 167–178)  相似文献   
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