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81.
ABSTRACT

The psychosocial theory of Gerotranscendence, is proposing an alternative and positive view of aging and states that human development is a lifelong process. Applying the concept of Gerotranscendence into the older adults’ lives may have the potential to provide a more positive view of aging and a better care for a growing population. First; and to do this, we need to use a proper, valid and reliable measure. The purpose of this cross-sectional and methodological study was to assess the psychometric properties of the Persian version of the short-form Gerotranscendence scale (GS-S) in community-dwelling Iranian older adults. First the scale was translated to Persian, and culturally adapted. Then pre-testing and cognitive interviewing implemented in a sample consisted of 10; and stability of the scale in a sample of 30 older adults, respectively. Confirmatory factor analysis and internal consistency of the scale were done with 250 older adults. The three-factor structure was confirmed. The model showed a good fit, and all the indices were satisfactory (RMSEA = 0.063; NNFI = 0.093; CFI = 0.095; IFI = 0.096; GFI = 0.095; and χ2/df = 2). Cronbach’s alpha of the scale was 0.72 and coefficient omega was 0.82. Test-retest reliability (ICC) was 0.88, P < .001; and standard error of measurement was 1.16 (CI = %95). Minimal detectable change (MDC) was 3.2 and minimal important change (MIC) was 1.4. This study supports the use of the GS-S as a measure of life span development among the Iranian older adults.  相似文献   
82.
Chlorella vulgaris (CV) has been reported to have antioxidant and anticancer properties. We evaluated the effect of CV on apoptotic regulator protein expression in liver cancer-induced rats. Male Wistar rats (200∼250 g) were divided into eight groups: control group (normal diet), CDE group (choline deficient diet supplemented with ethionine in drinking water to induce hepatocarcinogenesis), CV groups with three different doses of CV (50, 150, and 300 mg/kg body weight), and CDE groups treated with different doses of CV (50, 150, and 300 mg/kg body weight). Rats were sacrificed at various weeks and liver tissues were embedded in paraffin blocks for immunohistochemistry studies. CV, at increasing doses, decreased the expression of anti-apoptotic protein, Bcl-2, but increased the expression of pro-apoptotic protein, caspase 8, in CDE rats, which was correlated with decreased hepatoctyes proliferation and increased apoptosis as determined by bromodeoxy-uridine (BrdU) labeling and terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling (TUNEL) assay, respectively. Our study shows that CV has definite chemopreventive effect by inducing apoptosis via decreasing the expression of Bcl-2 and increasing the expression of caspase 8 in hepatocarcinogenesis-induced rats. Project supported by Department of Biochemistry, Faculty of Medicine, UKM Medical Center, Universiti Kebangsaan Malaysia, and the Malaysian Ministry of Science and Technological Innovation (MOSTI)  相似文献   
83.
α-Thalassemia (α-thal) is considered as the most common inherited hemoglobin disorder worldwide. The present study describes the first observation of a combination of rare α-chain variants, and β-globin gene cluster deletion. A 21-year-old woman with thalassemia trait, marked microcytosis, mild anemia, and normal range of Hb F was referred to Amirkola genetic center in the North of Iran for routine molecular test of thalassemia in the context of carrier detection and prevention of thalassemia major birth. Nucleotide sequencing revealed a novel compound heterozygosity status for two non-deletional mutations on HBA2, Hb O Indonesia (α116(GH4)Glu → Lys), and Hb Matsue–Oki (α75 (EF4) Asp → Asn), together with heterozygosity for the sicilian (δβ)0-thal mutation. This finding highlights the necessity of deep molecular investigation of thalassemia in regions where thalassemia is abundant, and present highly heterogeneous population.  相似文献   
84.
85.
Eye injuries from blunt forces and penetrating objects can cause morbidity, disability, and blindness. Most of these injuries are preventable not only by understanding the detail of injury, but also by portraying the role of the ball’s characteristics. Basketball can induce severe forms of injuries to the eye. This study was aimed at performing a numerical analysis through the fluid–structure interaction on ocular trauma. Balls with different diameters, elastic moduli, and pressures were shot to the eye. Injury in terms of the stresses and deformations in each component of the eye was computed at ~?0.72 mm deformation in the apex of the cornea. By increasing the diameter of the ball from 20 to 26 cm the stress in the eye components, excluding the aqueous body, vitreous body, and extraconal fat, increased. Stresses of 2.68 and 3.19 MPa were observed in the cornea under the ball diameters of 20 and 26 cm, respectively. Conversely, the elastic modulus and pressure of the ball in the defined range showed no considerable role on the stress in the eye components. The results revealed the importance of the ball size compared to the elastic modulus and pressure in the stress accumulation as a result of ocular trauma.  相似文献   
86.
This article investigates the e-print depositing behavior of physicists and astronomers. Fifty-six PhD students and staff at the Department of Physics and Astronomy at the University College London were interviewed. A survey was also carried out (47.1% response rate). The study investigates the relation between variables such as research area, type of research (theoretical, experimental and so on), and the amount of reading on the patterns of e-print depositing. The findings showed that clear intradisciplinary differences exist among different subfields of physics and astronomy.  相似文献   
87.
In this work, the cruise control problem of high-speed trains’ movements is investigated. Both cases of a single high-speed train and multiple high-speed trains are under consideration. Different with most existing studies where the centralized control or the decentralized control methods are adopted based on a single point mass model of the train, in this paper, a distributed control mechanism is proposed by virtue of the graph theory, and the high-speed train’s model is built as a cascade of point masses connected by flexible couplers. For a single high-speed train, the neighboring cars interact through the coupling force with each other, which can be described by a connected topological graph by regarding each car as a node. Besides, the speed information communication among the cars is considered to be described by another directed topological graph. A distributed control strategy is then developed, with which all the cars of a train track a desired speed asymptotically and the neighboring cars keep a safety distance from each other. For the multiple high-speed trains running on a railway line, the in-train force interaction topology and the speed information communication topology of all the trains are more complex than those of a single train. A new cluster consensus technique is developed, by which a distributed control law is designed. Under the control law, the trains can track the desired speeds asymptotically, the headway distance between adjacent trains and the distance between the neighboring cars of a train can be kept in appropriate ranges. Finally, simulations are provided to illustrate the effectiveness of the obtained theoretical results.  相似文献   
88.
Flow cytometry has been employed as a method to study homogeneity of isolated islet subpopulations. After collagenase digestion of rat pancreas and elutriation of tissue fragments, islets were isolated and dissociated, and cells were analyzed and sorted according to their low forward angle light scattering properties by using automated flow cytometry. A standardized procedure was developed for the preparation of rat islet cell grafts for purification of islet cells. In this process, after collagenase digestion of pancreas, islets were isolated, dissociated, identification by dithizone method and then with enzymatic procedure by DNase and trypsin, the islet cells changed into single cells and beta cells were identified by immunofluorescence method and then assayed by flow cytometry. Methods have been developed for the preparation of suspension of viable rat pancreatic islet cells and their analysis and sorting in the fluorescence activated cell sorter (FACC IV, Becton Dickinson, Sunnyvale, Ca). Flow cytometry of these cells indicated that there were 91% of beta cells in cell suspension. Most of the exocrine particles were lost during digestion. Purified endocrine islet cell grafts were prepared by pure beta-cells, without endocrine non-beta cells. The purified aggregates were devoid of endocrine non-beta cells and damaged cells.  相似文献   
89.
This article examines the impact of subtractive schooling, including language use in education, on the identity of a group of ethnic minority students in Central Highlands of Vietnam. Drawing on semistructured interview data, a deeper look is taken into the ways in which these students identify themselves with their languages, cultures, and social relations. Findings reveal that the subtractive power of the school language and the institutional milieu profoundly influenced their identity construction by creating the conditions for (a) the devaluation of their language and cultural identity as a consequence of the invasion of their sociocultural territory by the dominant language and culture and (b) the segregation and disunity that affected their identity construction through social relations. Although subtractive schooling apparently facilitated students’ integration into the mainstream, its invisible power forced them not only to integrate but also to bear the full burden of constructing new identities to adjust to the school environment and the mainstream society.  相似文献   
90.
Let G be a weighted graph with adjacency matrixA=[aij]. An Euclidean graph associated with a molecule is defined by a weighted graph with adjacency matrix D=[dij], where for i≠j, dij is the Euclidean distance between the nuclei i andj. In this matrix dij can be taken as zero ifall the nuclei are equivalent. Otherwise, one may introduce different weights for different nuclei. Balasubramanian (1995) computed the Euclidean graphs and their automorphism groups for benzene, eclipsed and staggered forms of ethane and eclipsed and staggered forms of ferrocene. This paper describes a simple method, by means of which it is possible to calculate the automorphism group of weighted graphs. We apply this method to compute the symmetry of tetraammine platinum(Ⅱ) with C2v and C4v point groups.  相似文献   
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