排序方式： 共有48条查询结果，搜索用时 15 毫秒
31.
M Maneesh H Jayalekshmi Sanjiba Dutta Amit Chakrabarti D M Vasudevan 《Indian journal of clinical biochemistry : IJCB》2005,20(2):62-67
The study was undertaken to evaluate the possible involvement of oxidative stress in the pathogenesis of ethanol induced testicular
atrophy in rats. Adult male rats were orally administered ethanol at a dose of 1.6 g/kg body weight/day for four weeks. Twenty-four
hours after the last treatment the rats were sacrificed using anesthetic ether. Testes were removed and weighed. Apoptosis
was studied by using the Feulgen reaction on 5 μ thin paraffin sections of testis. Testicular homogenate was prepared and
centrifuged. The supernatant was used for the estimation of extent of lipid peroxidation and antioxidant defense status. There
was significant reduction in body weight: and in testicular weight and diameter in ethanol treated rats. Extent of germ cell
apoptosis was significantly high in ethanol treated rats. Ethanol treated rats showed significantly high tissue TBARS level
and glutathione S-transferase activity; and low tissue ascorbic acid, reduced glutathione, superoxide dismutase, catalase,
glutathione peroxidase and glutathione reductase activities. Chronic ethanol administration resulted in high oxidative stress
in the testes either due to increased extent of lipid peroxidation or due to decreased antioxidant defenses, and thereby induces
germ cell apoptosis leading to testicular atrophy. 相似文献
32.
Pathogens, especially Gram-negative bacteria or bacterial endotoxin, along with other classical factors, may be involved in
inflammatory response within the aortic endothelium during the progression of cardiovascular disease. Studies have shown that
bacterial endotoxin activates various inflammatory processes in the body. Our study aims to establish a correlation between
endotoxemia and vascular expression of antioxidant enzymes. Swiss albino mice (4 weeks old) were fed a high fat diet for 24
weeks and then were administered Escherichia coli endotoxin intraperitonealy, for 4 weeks. Tissue antioxidant enzymes, serum
levels of IL-6 and TNF alpha were measured from the mice. We report that i.p. administration of endotoxin to hyperlipidemic
mice resulted in elevation of superoxide dismutase and catalase enzymes, which was paralleled by a systemic reduction of serum
cholesterol and LDL expression. Myeloperoxidase levels were also found to be elevated in aortic tissue, while an increase
was also observed in the serum cytokine levels. 相似文献
33.
Mohan J. Dutta 《传播与批判/文化研究》2020,17(2):228-235
ABSTRACT The essay explores the mobility of Whiteness in networks of Communication Studies that posture themselves as speaking from the Global South. Depoliticized languages of de-westernizing, internationalizing, and decolonizing are often articulated by elites in North-South networks pushing neoliberal governmentality, erasing claims to radical equality that emerge from within socialist struggles in the Global South. In resistance, a radical framework of knowledge from the Global South emerges from within subaltern struggles for hegemony, achieved through (a) delinking from the metropoles of the North and (b) explicitly crafting a socialist anticolonial politics that names and dismantles Whiteness as a capitalist project. 相似文献
34.
Kapil D. Lahiri Jayanta Dutta Himadri Datta Harendra N. Das 《Indian journal of clinical biochemistry : IJCB》2013,28(1):61-64
Total plasma homocysteine was analysed in 64 cases of retinal vein occlusion (RVO) of which 24 cases of central retinal vein occlusion (CRVO) and 40 cases of branch retinal vein occlusion (BRVO) and compared with 45 age and sex matched control. Homocysteine was significantly increased in RVO cases in respect to control (P < 0.001). Analysis also revealed that prevalence of rise of plasma homocysteine was more in cases of CRVO (OR = 13) than that of BRVO (OR = 5.03). 相似文献
35.
Joydeep Dutta Chaudhuri 《Anatomical sciences education》2022,15(5):910-927
It is universally recognized that cadaveric dissection is an essential part of anatomy training. However, it has been reported to induce mental distress in some students and impair their intrinsic motivation (IM) to study. One of the postulated reasons for this behavior is the lack of adequate information and preparation of students for cadaveric dissection. Therefore, it is hypothesized that providing relevant information prior to cadaveric dissection will ameliorate the mental distress, enhance the IM of students, and improve their academic performance. A cohort of occupational therapy students enrolled in an anatomy course were psychologically prepared for cadaveric dissection. Students were provided with a curated list of YouTube videos and peer-reviewed journal articles related to cadaveric dissection prior to the commencement of the anatomy course. All students were also required to attend an oral presentation immediately before commencing dissection. The control group included students who had not been provided with any resources in preparation for cadaveric dissection. Compared to the control group, students who had been prepared demonstrated better quality of cadaveric dissection, improved academic performance, reported less mental distress and greater IM. Moreover, students reported the oral presentation to be most relevant and journal articles to be least useful in their preparation. Therefore, this is an effective approach in the amelioration of mental distress and improvement of performance in anatomy students. Consequently, this study represents a paradigm shift in the pedagogy of anatomy, and could represent a vital element in the evolution of a revitalized anatomy curriculum. 相似文献
36.
Even though isoelectric focusing (IEF) is a very useful technique for sample concentration and
separation, it is challenging to extract separated samples for further processing. Moreover, the
continuous sample concentration and separation are not possible in the conventional IEF. To overcome
these challenges, free flow IEF (FFIEF) is introduced in which a flow field is applied in the
direction perpendicular to the applied electric field. In this study, a mathematical model is developed for FFIEF to understand
the roles of flow and
electric fields for
efficient design of microfluidic
chip for continuous separation of proteins from an initial well mixed solution. A finite volume based
numerical scheme is implemented to simulate two dimensional FFIEF in a microfluidic chip. Simulation results
indicate that a pH gradient forms as samples flow downstream and this pH profile agrees well with
experimental results validating our model. In addition, our simulation results predict the experimental behavior of
pI markers in a FFIEF microchip. This numerical model is used to predict the separation
behavior of two proteins
(serum albumin and cardiac troponin I) in a two-dimensional straight microchip. The effect of
electric field is
investigated for continuous separation of proteins. Moreover, a new channel design is presented to increase the separation
resolution by introducing cross-stream flow velocity. Numerical results indicate that the separation
resolution can be improved by three folds in this new design compare to the conventional straight
channel design. 相似文献
37.
Recent studies show that reduction in cross-sectional area can be used to improve the concentration factor in microscale bioseparations. Due to simplicity in fabrication process, a step reduction in cross-sectional area is generally implemented in microchip to increase the concentration factor. But the sudden change in cross-sectional area can introduce significant band dispersion and distortion. This paper reports a new fabrication technique to form a gradual reduction in cross-sectional area in polymethylmethacrylate (PMMA) microchannel for both anionic and cationic isotachophoresis (ITP). The fabrication technique is based on hot embossing and surface modification assisted bonding method. Both one-dimensional and two-dimensional gradual reduction in cross-sectional area microchannels were formed on PMMA with high fidelity using proposed techniques. ITP experiments were conducted to separate and preconcentrate fluorescent proteins in these microchips. Thousand fold and ten thousand fold increase in concentrations were obtained when 10 × and 100 × gradual reduction in cross-sectional area microchannels were used for ITP. 相似文献
38.
Kishore Dutta 《Resonance》2016,21(4):339-351
One of the highly striking yet poorly understood natural phenomena is the song of dunes. Some sand dunes in deserts are capable of emitting a loud persistent sound with a characteristic audible low-frequency (≈ 75—105 Hz), that can sometimes be heard up to 10 km away. Scientific in-vestigations suggest that the sustained low fre-quency sound of sand dunes that resembles a pure note from a musical instrument, is due to the synchronized motion of well-sorted dry sand grains when they spontaneously avalanche under gravity. This article describes the underlying mechanism for sustained sound emission in singing sand dunes in light of recent physical ex-periments. 相似文献
39.
Amartya Kumar Dutta 《Resonance》2006,11(4):56-74
In the first part of this series, we discussed the celestial sphere and Aryabhata’s principle of axial rotation; in this part
we shall discuss in detail the concept of sidereal day and then mention Aryabhata’s computations on the duration of sidereal
day. 相似文献
40.