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61.
Singh TD Barbhuiya MA Gupta S Shrivastav BR Jalaj V Agarwal N Tiwari PK 《Indian journal of clinical biochemistry : IJCB》2011,26(2):146-153
We have studied the expression of lactate dehydrogenase and its isoforms in gall bladder cancer, cholelithiasis and chronic
cholecystitis. Quantitative and qualitative assays of lactate dehydrogenase and its various isoforms were carried out in the
blood sera of patients and healthy controls along with parallel estimation of various liver function test enzymes. Statistical
analysis was done using the software Graph Pad Prism. Significantly high expression of lactate dehydrogenase along with alkaline
phosphatase and total bilirubin (P ≤ 0.05) was observed in all the three clinical conditions as compared to controls. LDH showed an increasing trend from stage
I to stage IV of GBC indicating a significant positive association with the disease progression. The levels of LDH 3 and 4
isoforms appeared significantly more elevated in GBC than cholelithiasis or chronic cholecystitis. We suggest that a careful
estimation of total LDH and its isoforms 3 and 4 alone or along with alkaline phosphatase and total bilirubin during different
clinical stages, like chronic cholecystitis, cholelithiasis and GBC, may prove to be a potentially useful biomarker in the
prognostic management of gall bladder diseases, specifically GBC. 相似文献
62.
This study investigates the acceptance and importance of digital library among female students of International Islamic University, Islamabad, Pakistan. The study also highlights the problems that are confronted by the female students in completing their research work after limited access to digital library in the female campus of the University.Survey was administered personally to collect data from 315 female students of eight faculties of the female campus of the university. The convenient sampling technique was used to collect data from the subjects of the study.The access to digital library is indispensable to the students to complete their research work. With limited access to the digital library the students were unable to meet their information needs from the Internet and the libraries of other universities. The quantity as well as quality of their research work were affected due the restriction of digital resources. Also the limited access affected adversely to improve insight of the respondents regarding technological developments in their respective area of research. The lack of informational literacy program, IT training workshops, IT literate staff and the electricity failure were the main hindrance to access digital library as well as Internet.This study was limited only to female students of the International Islamic University, Islamabad, Pakistan. 相似文献
63.
The use of digital media is on rise around the world and same phenomenon is emerging in Pakistan. The study was intended to explore the use of digital media and demand for digitized contents in higher education sector of Pakistan. The research questions were answered by a comprehensive literature review along with semi-structured in-depth interviews of 25 library experts. The findings conferred that the use of digital media in higher education is on rise and demand for digitized contents is growing increasingly. The findings of the study made a good case for the libraries to focus more on acquisition of information resources in digital formats as well as initiate digitization initiatives. 相似文献
64.
Narotam Sharma Veena Sharma Prem Raj Singh Shivani Sailwal Rajeev S. Kushwaha Rajesh K. Singh Satish C. Nautiyal Pankaj Mishra Tariq Masood R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):305-308
Genitourinary tuberculosis is a disease of the genitourinary system which includes the entire urinary tract and reproductive system. Genital tuberculosis is an important cause of female infertility, especially in developing nations like India. In the present study, a total of 257 clinical specimens comprising of endometrial biopsy (109), endometrial curetting (42), menstrual blood (8), semen (17), placenta (11) and urine (70) were collected from patients and subjected for PCR, Culture and AFB detection. The endometrial biopsy, endometrial curetting, menstrual blood, semen, placenta, urine showed 30.2, 45.2,12.5, 5.8, 27.2, 31.4 %, positivity rate for tuberculosis by PCR, 7.3, 9.5, 25.0, 0, 9, 8.5 % by culture and 1.8, 2.3, 0, 0, 0, 2.8 % respectively by AFB smear. Being a novel, rapid technique, PCR is the method of choice for rapid diagnosis and management of genitourinary tuberculosis shared with the other concerned tests. This study reveals that genital tuberculosis can occur in any age group, however, the majority of patients were from reproductive age (nearly 75 % of them were from 20–45 years of age) group. 相似文献
65.
Kanwal Ameen 《Learned Publishing》2017,30(2):133-142
This paper aims to investigate the practices of Pakistani academic researchers with respect to using, citing, and publishing their scholarly work. The quantitative survey method adopted to collect data from local researchers was based on an instrument developed and used by CIBER. Their notions and practices involved in deciding trust and quality of scholarly journals were obtained. The findings revealed that national and institutional policies have significantly influenced their decisions regarding the publishing outlets. The credibility of indexing services was found to be an important factor in choosing the journal for publishing research. ISI Web of Science Impact Factor was not considered as the top source for determining quality and trustworthiness. This study is the first of its kind that targets the top two universities of the country. A comparison of the findings with another international study shows that some of the behavioural traits are compatible with scholars from less‐developed countries like India and China, while others are more similar to the ones from highly developed countries like USA and UK. 相似文献
66.
Creativity is usually defined in terms of the production end of ideas or products, yet a neglected aspect of creativity, though no less vital, is the process by which creative products are critically evaluated, selected, altered or dismissed by the creator. Any attempt to promote creative thinking skills in schools needs to also address this aspect of critical thinking in creativity—failure to do so results not in usefully creative children, but merely indulgent ones. 相似文献
67.
Interchange - With frequent curriculum changes in South Africa since 1994, educational standards and learner performance has been progressing at a slow pace. The role of the principal’s... 相似文献
68.
Ranjana Singh Sumita Sharma Raj K. Singh Germaine Cornelissen 《Indian journal of clinical biochemistry : IJCB》2016,31(2):215-223
The circadian rhythm of human circulating lipid components was studied under nearnormal tropical conditions in 162 healthy volunteers (103 males and 59 females; 7 to 75 years of age). They followed a diurnal activity from about 06:00 to about 22:00 and nocturnal rest. These volunteers were divided into four groups: Group A (7–20 years), Group B (21–40 years), Group C (41–60 years) and Group D (61–75 years), comprising 42, 60, 35 and 25 participants, respectively. A marked circadian rhythm was demonstrated for each studied variable in each group by population-mean cosinor analysis (almost invariably p < 0.001). Furthermore, circadian rhythm characteristics were compared among the 4 groups by parameter tests and regressed as a function of age, separately for males and females. A second-order polynomial characterized the MESOR of HDL cholesterol, phospholipids and total lipids, as well as the 24-h amplitude of total cholesterol and phospholipids. The 24-h amplitude of total lipids decreased linearly with age. The 24-h acrophase of the oldest age group (Group D) was advanced in the case of total cholesterol, HDL cholesterol, and total lipids, whereas that of phospholipids was delayed. Mapping the circadian rhythm (an important component of the broader time structure or chronome, which includes a. o., trends with age and extra-circadian components) of lipid components is needed to explore their role in the aging process in health. 相似文献
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The use of digital media is on rise around the world and same phenomenon is emerging in Pakistan. The study was intended to explore the use of digital media and demand for digitized contents in higher education sector of Pakistan. The research questions were answered by a comprehensive literature review along with semi-structured in-depth interviews of 25 library experts. The findings conferred that the use of digital media in higher education is on rise and demand for digitized contents is growing increasingly. The findings of the study made a good case for the libraries to focus more on acquisition of information resources in digital formats as well as initiate digitization initiatives. 相似文献