Why are we not blinded by the star light?     

N Kumar 《Resonance》2000,5(7):56-59

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Immunobiology of trophoblast cells     

Chandana Das  V. Senthil Kumar  Sayantani Basak  Surabhi Gupta  Sunesh Kumar 《Indian journal of clinical biochemistry : IJCB》2000,15(1):60-62

A female patient who had two primary cancers was investigated. Biochemical analysis of patient's serum for different parameters indicated an alteration in the metabolic process. Prognostically, the patient has shown favourable clinical features.  相似文献   

Large scale development of learning materials: Critical issues     

Krishna Kumar Bhardwaj  Prabish Chandran  A. F. O'Neal  Andrew S. Gibbons 《Educational technology research and development : ETR & D》1998,46(2):101-110

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Diagnosis of gastrointestinal tuberculosis: Using cytomorphological,microbiological, immunological and molecular techniques — A study from Central India     

Pradyumna Kumar Mishra  A. Bhargava  R. P. Punde  N. Pathak  P. Desikan  A. Jain  S. Varshney  K. K. Maudar 《Indian journal of clinical biochemistry : IJCB》2010,25(2):158-163

The present study included three groups: (A) age and gender matched control (n=24) with no previous signs of M. tuberculosis complex (MTBC) infection, (B) patients (n=28) diagnosed with gastro-intestinal TB (GITB), (C) patients (n=50) with clinical and histo-pathological signs of GITB, but were culture and AFB negative. Real time assay performed using fluorescence resonance energy transfer hybridization probes showed a positivity index of 36 % in group C, i.e. 18 were found reactive from the total 50 cases studied. In addition, immune characterization of these 18 cases showed depleted CD₄⁺ count and increased levels of IFN-γ and TNF-α cytokines. No positive case was found in group A, while in group B, out of total 28 cases studied 27 were found positive. A combinatorial diagnostic approach for rapid detection and characterization of GITB might provide specific therapeutic strategies for prevention and treatment of the infection in future.  相似文献   

Cerebro-spinal and renal ochronosis: A rare case report     

Sunil Kumar Nanda  D. R. Suresh  A. Vamseedhar  K. Pratibha  B. Arjun 《Indian journal of clinical biochemistry : IJCB》2010,25(2):213-216

Alkaptonuria, a rare inborn error of tyrosine metabolism, characterized by the absence of homogentisic acid oxidase results in the accumulation of homogentisic acid in the body. Associated renal failure and cerebral infarction is rare and usually occurs in the later stages of the disease. We report a 55-year-old male who presented, initially with features of stroke and degenerative arthritis. He had pigmentation of sclerae, darkening of urine on long standing, abnormal renal profile, degenerative arthritis and cerebral infarction. Alkaptonuria was suspected and biochemical tests confirmed mild renal impairment, homogentisic acid in urine and homogentisic acid crystal was detected cytologically in urine sediment. Such a case of Alkaptonuric ochronosis with cerebrovascular and renal complications have been rarely reported in the previous literature.  相似文献   

A new perspective on in vitro assessment method for evaluating quantum dot toxicity by using microfluidics technology     

Sanjeev Kumar Mahto  Tae Hyun Yoon    Seog Woo Rhee 《Biomicrofluidics》2010,4(3)

In this study, we demonstrate a new perspective on in vitro assessment method for evaluating quantum dot (QD) toxicity by using microfluidics technology. A new biomimetic approach, based on the flow exposure condition, was applied in order to characterize the cytotoxic potential of QD. In addition, the outcomes obtained from the flow exposure condition were compared to those of the static exposure condition. An in vitro cell array system was established that used an integrated multicompartmented microfluidic device to develop a sensitive flow exposure condition. QDs modified with cetyltrimethyl ammonium bromide∕trioctylphosphine oxide were used for the cytotoxicity assessment. The results suggested noticeable differences in the number of detached and deformed cells and the viability percentages between two different exposure conditions. The intracellular production of reactive oxygen species and release of cadmium were found to be the possible causes of QD-induced cytotoxicity, irrespective of the types of exposure condition. In contrast to the static exposure, the flow exposure apparently avoided the gravitational settling of particles and probably assisted in the homogeneous distribution of nanoparticles in the culture medium during exposure time. Moreover, the flow exposure condition resembled in vivo physiological conditions very closely, and thus, the flow exposure condition can offer potential advantages for nanotoxicity research.  相似文献   

Managerial Network Impacts Firm Performance     

Debadutta Kumar Panda 《Performance Improvement Quarterly》2014,27(1):5-32

This study measures the impact of managerial networks on firm growth. A simple random technique was used to select 680 firms and a top manager from each firm. A structured pretested questionnaire was designed to collect information. The sample firms were further stratified into subgroups based on size of firms (small firms and large) and business sectors (manufacturing and service firms). Statistical tests and multivariate models were formulated for data analysis. The managerial networking intensity was found to be a positive and significant determinant of firm growth regardless of type of business and size. Managerial networking with buying firms or buyers, competitors, and government officials were found positive and statistical significant determinants of firm growth.  相似文献   

Navigating privacy tensions when responding to online aggression at postsecondary institutions     

Virginia L. Byrne  Juana Hollingsworth  Priya C. Kumar 《British journal of educational technology : journal of the Council for Educational Technology》2023,54(6):1636-1652

Postsecondary institutions have a legal responsibility to ensure that students have access to a safe learning environment. While institutions adopt policies and hire administrators to protect students from harm, many are underprepared to support students when these harmful incidents happen online. This is of increased concern now that online aggression is pervasive across universities worldwide. While faculty, administrators and students agree that online aggression is a significant issue and that institutions ought to provide prevention and response services, there is concern that these efforts might violate privacy norms. We used the theory of privacy as contextual integrity (CI) to explore the tensions that postsecondary students and staff perceive regarding student privacy when responding to incidents of online aggression. To do so, we conducted focus groups with undergraduate students and student affairs administrators from a Historically Black College and University (HBCU) in the Mid-Atlantic USA. Our analysis surfaced three considerations that inform students' and staff's decision to report an incident of online aggression: their closeness to the person making the post, their perception of the online post content as a real threat and their knowledge of an authority figure who could help resolve the situation. We used CI theory to explain how these considerations can inform institutional policy, practice and future research.

Practitioner notes

What is already known about this topic

• Online aggression is a pervasive issue at postsecondary institutions worldwide that can contribute to psychological, academic and developmental issues.
• Postsecondary students and staff are unsure of how to respond to incidents of online aggression.
• There is a gap in policies and procedures for responding to online aggression at postsecondary institutions.

What this paper adds

• A novel use of Nissenbaum's (2010) theory of contextual integrity to understand students' and staff's perceptions of privacy.
• Students' and staff's decisions to intervene or report an online aggression incident are determined by their relationship to the perpetrator, the severity of the social media post and their knowledge of who to tell on campus.
• Students and staff are reluctant to inform the police out of fear of violence against the perpetrator.

Implications for practice and/or policy

• Raise awareness about responding to online aggression incidents.
• Implement online bystander intervention training programs to increase awareness and self-efficacy to intervene in unclear situations.
• Develop clear policies regarding online aggression, as well as a trustworthy procedure for how to respond.

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Personalized and Adaptive Context-Aware Mobile Learning: Review,challenges and future directions     

Gumbheer  Chandra Prakash  Khedo  Kavi Kumar  Bungaleea  Anjali 《Education and Information Technologies》2022,27(6):7491-7517

Education and Information Technologies - Due to the outbreak of COVID 19, digital learning has become the most efficient learning and teaching technique adopted across the world. The pervasiveness...  相似文献   

Evolving strategies in whirlwind mode: The changing face of anatomy education during Covid-19 pandemic     

Sanjib Kumar Ghosh 《Anatomical sciences education》2022,15(6):1103-1119

The Covid-19 pandemic stipulated adoption of unfamiliar strategies for delivering anatomy education in online mode. The factors which determine education strategies are variable across geographical regions. It was perceived that an overview of education strategies around the globe would be useful for anatomists. Hence this narrative review was undertaken to collate observations from different geographical regions pertaining to education strategies adopted during the pandemic. Data relevant to the topic of study were extracted from 12 articles that were selected from an initial pool of 317 articles based on search criteria set for the review. Subtle differences in core education strategies implied that baseline response from anatomists was similar across regions. It was evident that online digital tools were key elements of education strategies adopted by educators for delivering online anatomy classes across the globe. Interestingly, a considerable gap in terms of number and variety of online tools used for anatomy education (those requiring commercial purchase) was noted between economically developed and developing regions. This may have an impact on learning outcome for students and may even lead to variations in anatomical knowledge by regions. It was observed that offline human dissection sessions were incorporated into online practical classes in one region as positive cases showed a declining trend. This positive development is worth emulating elsewhere based on cautious assessment of prevailing situation. From a broad perspective timely introduction of education strategies ensured delivery of anatomy education during the pandemic and gave an evolved outlook to the fabric of anatomy education.  相似文献