Therapeutic radionuclides in nuclear medicine: current and future prospects     

Chai-Hong Yeong  Mu-hua Cheng  Kwan-Hoong Ng 《Journal of Zhejiang University. Science. B》2014,15(10):845-863

The potential use of radionuclides in therapy has been recognized for many decades. A number of radionuclides, such as iodine-131 (¹³¹I), phosphorous-32 (³²P), strontium-90 (⁹⁰Sr), and yttrium-90 (⁹⁰Y), have been used successfully for the treatment of many benign and malignant disorders. Recently, the rapid growth of this branch of nuclear medicine has been stimulated by the introduction of a number of new radionuclides and radiopharmaceuticals for the treatment of metastatic bone pain and neuroendocrine and other malignant or non-malignant tumours. Today, the field of radionuclide therapy is enjoying an exciting phase and is poised for greater growth and development in the coming years. For example, in Asia, the high prevalence of thyroid and liver diseases has prompted many novel developments and clinical trials using targeted radionuclide therapy. This paper reviews the characteristics and clinical applications of the commonly available therapeutic radionuclides, as well as the problems and issues involved in translating novel radionuclides into clinical therapies.  相似文献   

School‐to‐work transition services for students with disabilities in Malaysia: organisations' views on policy and practices     

Melissa Ng Lee Yen Abdullah  See Ching Mey  Tan Kok Eng  Rosly Othman  Ahmad Fairuz Omar 《Journal of Research in Special Educational Needs》2013,13(4):259-271

Transition services are required by law for students with disabilities in many developed countries. In Malaysia, however, there is still no specific legislation mandating that school‐to‐work transition planning and services be provided to students with disabilities. This study investigated the state of the transition services provided by educational organisations to students with disabilities in Malaysia. A mixed method research design, which utilises both quantitative and qualitative research techniques, was employed to obtain information from 23 government organisations and NGOs involved in the education and training of students with disabilities. This study found that the organisations surveyed were aware of the lack of transition support and call attention to the importance of instituting a national policy on school‐to‐work transition services and supported employment systems for students with disabilities. The legislative and educational implications for Malaysia are discussed.  相似文献   

Developing Singapore school leaders to handle complexity in times of uncertainty     

Pak Tee Ng 《Asia Pacific Education Review》2013,14(1):67-73

In times of uncertainty, university faculties have a duty to prepare school leaders to handle complexity, as the number of variables in the educational system and the interactivity of variables increase exponentially. The Leaders in Education Program (LEP) is a 6-month full-time program at the Singapore National Institute of Education (NIE, which is a part of Nanyang Technological University). The LEP aims to prepare especially selected vice-principals and ministry officers in Singapore for school leadership. The LEP is a collaborative effort between the NIE and the Ministry of Education, an example of a university–government partnership in program development. This article describes the efforts of the LEP in developing the ability of school leaders to deal with complexity. It also examines in detail one particular component of the LEP, the Creative Action Project, to illustrate how this is done in practice, and analyzes the views of participants on their learning through the project.  相似文献   

Three Levels of Goal Orientation in Learning     

Evelyn Ng  Carl Bereiter 《学习科学杂志》2013,22(3-4):243-271

Sixteen adult volunteers provided thinking-aloud protocols while undergoing a 10-hr individually administered course in BASIC (beginner's all-purpose symbolic instruction code) programming. Three levels of goals were identified as operative in the learning situation: task-completion goals, instructional goals, and personal knowledge-building goals. Although protocol statements indicating knowledge-building goals were infrequent, students exhibiting a relatively high proportion of them were distinctive in several ways. They did significantly better on a posttest. Their performance in goal cue selections differed from that of other participants in ways consistent with their orientation: They responded more often to learning goal cues than to task goal cues. They actively related new learning to prior knowledge and they posed and tried to solve problems and questions. Students oriented toward instructional goals tended to focus on what was explicitly taught. Students oriented toward task-completion goals tended to equate learning with successful completion of assigned tasks. Level of goal orientation and posttest performance were unrelated to level of education and prior computer experience but were positively related to previous experience of independent learning.  相似文献   

Kidney function change after transcatheter aortic valve replacement in patients with diabetes and/or hypertension     

Jiaqi FAN  Changjie YU  Kaida REN  Wanbing LIN  Stella NG  Zexin CHEN  Xinping LIN  Lihan WANG  Qifeng ZHU  Yuxin HE  Jubo JIANG  Xianbao LIU  Jian'an WANG 《Journal of Zhejiang University. Science. B》2021,22(3):241-247

Aortic stenosis(AS)is a progressive heart valve disease occurring predominantly in older patients.According to a survey in a western country,the prevalence of AS is nearly 6.4%in patients over 75 years old(Carabello and Paulus,2009).Transcatheter aortic valve replacement(TAVR)is an alternative method for AS patients.Previous studies have described how up to 66%of TAVR patients have concomitant baseline kidney dysfunction(Ferro et al.,2015;Gargiulo et al.,2015).The majority of patients can benefit from the TAVR procedure with the recovery of kidney function.  相似文献   

Self-schematic students in mathematics and their contrasting coping responses to mathematical challenges: a cluster analytic investigation     

Ng  Clarence 《Educational Studies in Mathematics》2021,107(2):315-338

Educational Studies in Mathematics - Mathematics self-schemas are students’ cognitive generalisations of their selves in learning mathematics (Ng in Educational Psychology, 34(6),...  相似文献   

Immigrant Chinese Mothers’ Socialization of Achievement in Children: A Strategic Adaptation to the Host Society          下载免费PDF全文

Florrie Fei‐Yin Ng  Irene Nga‐Lam Sze  Catherine S. Tamis‐LeMonda  Diane N. Ruble 《Child development》2017,88(3):979-995

Academic socialization by low‐income immigrant mothers from Mainland China was investigated in two studies. Immigrant Chinese mothers of first graders (n = 52; M_age = 38.69) in the United States (Study 1) and kindergartners (n = 86; M_age = 36.81) in Hong Kong (Study 2) tell stories that emphasized achieving the best grade through effort more than did African American (n = 39; M_age = 31.44) and native Hong Kong (n = 76; M_age = 36.64) mothers, respectively. The emphasis on achievement was associated with mothers' heightened discussion on discrimination (Study 1) and beliefs that education promotes upward mobility (Study 2), as well as children's expectations that a story protagonist would receive maternal criticism for being nonpersistent in learning (Study 2).  相似文献   

Quality assurance in the Singapore education system in an era of diversity and innovation     

Pak Tee Ng 《Educational Research for Policy and Practice》2007,6(3):235-247

This paper describes how Singapore attempts to balance the need for quality assurance and the need for educational diversity and innovation. The Singapore experience shows that this is a delicate balance. On the one hand, to promote diversity and innovation, the government attempts to decentralise its power to the schools. On the other hand, for quality assurance, the government sets up quality structures that reassert the centrality of government control. This paper examines the implications of such a strategy and the challenges that schools face in navigating a new paradigm of diversity and innovation while satisfying the requirements of quality assurance.  相似文献   

Self-regulated learning in Singaporean context: a congeneric approach of confirmatory factor analysis     

Betsy Ng  C.K. John Wang  W.C. Liu 《International Journal of Research & Method in Education》2017,40(1):91-107

The motivated strategies for learning questionnaire (MSLQ) is widely used as a self-report instrument to assess students’ motivation and self-regulation. This study utilized the MSLQ Junior High to examine the motivational beliefs and self-regulation of secondary school students (Grades 8 and 9) from Singapore. The instrument was slightly modified and administered to students (N?=?610) in mathematics and science classes. In the first sample, 314 students completed the MSLQ Junior High while a second sample of 296 students completed the revised MSLQ Junior High. Using a congeneric approach of confirmatory factor analysis (CFA), the five-factor measurement model was determined with the first sample. This measurement model was further supported using a second sample and its goodness-of-fit indices were compared with other CFA models. Statistical findings showed that the five-factor structure of the revised MSLQ Junior High had a good model fit. The present study contributes a novel methodological approach by investigating the parsimony confirmatory factor structure of the revised MSLQ Junior High in local academic contexts.  相似文献   

Auditing for Score Inflation Using Self-Monitoring Assessments: Findings From Three Pilot Studies     

Daniel Koretz  Jennifer L. Jennings  Hui Leng Ng  Carol Yu  David Braslow  Meredith Langi 《Educational Assessment》2016,21(4):231-247

Test-based accountability often produces score inflation. Most studies have evaluated inflation by comparing trends on a high-stakes test and a lower stakes audit test. However, Koretz and Beguin (2010) noted weaknesses of audit tests and suggested self-monitoring assessments (SMAs), which incorporate audit items into high-stakes tests. This article reports the first three trials of SMAs, evaluating whether SMAs can detect inflation that had already been documented. The studies were conducted with mathematics tests in three grades. Despite severe conservative biases, the audit component functioned as expected in many of the trials. The difference in performance between nonaudit and audit items was associated with factors that earlier research showed to be related to test preparation and score inflation, such as scoring just below the Proficient cut in the previous year and school poverty. However, a number of null findings underscore the need for additional research into the design of audit items.  相似文献