Leveraging Blockchain Technology for Indian Healthcare system: An assessment using value-focused thinking approach     

Rashmi G. Shukla  Anuja Agarwal  Vidhu Shekhar 《The Journal of High Technology Management Research》2021,32(2):100415

Indian Healthcare system is a complex and distinguished structure due to variety of factors viz. population size it serves, presence of organized and unorganized services of healthcare, economic disparity and governance structure among others. Extant research emphasizes on the aspects like transparency, trust, disintermediation, non-repudiation, benchmarking of processes and practices, traceability and data integrity among others to stimulate the Indian Healthcare system for an improvised and more effective format. Blockchain Technology is recent innovation that offers many of these aforementioned aspects as a feature to the host systems. However, it is critical to understand and articulate the utility of Blockchain Technology specific to the Indian Healthcare system. Further, it is important to gauge the requirement elicitation of key stakeholders for Blockchain Technology adoption in Indian Healthcare system w.r.t any attribute prioritization/customization or design considerations (Consensus mechanism, type of blockchain, smart contracts etc.). There have been some research works on aspects of Blockchain applications in Indian Healthcare but lack a strong perspective of stakeholder requirements. We use Value-Focused Thinking framework based on discussions with the stakeholders to address the above mentioned research premise. We identify Fundamental Objectives and Strategic Objectives from the stakeholder interactions that contribute to the strategic goal. This is a niche work with a significant analytical contribution from the information systems perspective of Blockchain Technology adoption in the Indian Healthcare ecosystem given the light of premises from realms of human agents, behavioural and applications requirement from a stakeholder viewpoint.  相似文献   

Association of Interleukin-6 and Myeloperoxidase with Insulin Resistance in Impaired Fasting Glucose Subjects     

Ashish Agarwal  Anupama Hegde  Charu Yadav  Afzal Ahmad  Poornima Ajay Manjrekar  Rukmini Mysore Srikantiah 《Indian journal of clinical biochemistry : IJCB》2017,32(1):33-38

Impaired fasting glucose (IFG) is a high risk subclinical condition for the progression of type 2 diabetes mellitus and the hyperglycemia seen in this condition is because of the development of insulin resistance (IR). Obesity, inflammation, oxidative stress and many other factors have been implicated in development of IR in type 2 diabetes mellitus and its successive complications. Current study was aimed to ascertain the correlation of inflammation and oxidative stress markers [interleukin-6 (IL-6) and myeloperoxidase (MPO)] with IR in subjects with IFG. In this study, 80 subjects (40 IFG, 40 healthy controls) aged 25–45 years were selected based on their fasting plasma glucose (FPG) values and clinical history. Serum insulin, IL-6 and MPO were estimated by ELISA method and IR was calculated using Homeostatic Model Assessment Index 2 (HOMA 2) calculator. Pearson’s correlation coefficient and independent sample ‘t’ test were used for statistical analysis. IL-6 and MPO were found to be significantly elevated in IFG group and both correlates significantly with IR (r 0.413, r 0.645). Only MPO had significant correlation with FPG (r 0.388). In conclusion, the association of altered levels of IL-6 and MPO with IR are suggestive of a role of inflammation and oxidative stress in the initiation and progression of IR in individuals with IFG.  相似文献