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Aiki Kaul Rishi Sethi Mithilesh K. Misra 《Indian journal of clinical biochemistry : IJCB》2009,24(1):49-51
A comparative study on the levels of erythrocyte adenosine deaminase and lipid peroxidation has been undertaken in post myocardial
infarction angina patients along with age and sex matched healthy individuals serving as control. Present findings show that
levels of adenosine deaminase is highly elevated in post myocardial infarction angina patients compared to healthy persons.
Malondialdehyde levels are also significantly increased in post myocardial infarction angina patients. The study shows that
adenosine deaminase has an important implication in ischemic myocardial syndrome. 相似文献
33.
Pratima Tripathi M. K. Misra Shivani Pandey 《Indian journal of clinical biochemistry : IJCB》2012,27(3):296-299
Oxidative stress conditions associated with atherosclerosis leads to oxidative modification of low-density lipoprotein (LDL). The body’s capabilities to inhibit LDL oxidation and to remove or neutralize the atherogenic oxidized LDL (ox-LDL) are limited. When the LDL cholesterol level increases in the blood, it leads to dangerous consequences like atherosclerosis, leading to myocardial infarction. The major effect of an antioxidant in the LDL environment is to prevent the formation of ox-LDL (during atherogenesis. Strategies to reduce LDL oxidation and prevent atherogenesis can involve the enrichment of arterial cells with potent antioxidants that can prevent oxidative damage to the arterial wall. The objective of this study is to evaluate the effect of l-arginine on serum lipid and cholesterol levels in the patients of acute myocardial infarction (AMI). The study consisted of 70 AMI patients and 60 healthy individuals (serving as control) age 55–65 years. Serum levels of total cholesterol, high density lipoprotein (HDL), LDL and Triglycerides were determined on day 1 and day 15 of l-arginine administration (oral dose 3 g/day). The total cholesterol/HDL and the LDL/HDL ratio were calculated and compared. As per the observations, l-arginine administration was found to improve the lipid profile of the subjects. Hence it could be used as an adjuvant therapy for AMI and as a preventive measure for the onset of the disease in the healthy elderly also. 相似文献
34.
Sarah Misra 《The International Journal of Art & Design Education》2019,38(3):691-699
Since the publication of the Dearing Report in 1997, the UK Government has consistently promoted social mobility and fairness as part of its rhetoric. Yet as Brooks and others have pointed out, compared with other groups of ‘non‐traditional’ students, student mothers and part‐time students with jobs have been given limited consideration, both in terms of policy intervention and research. Despite the drive for inclusivity in higher education institutions, students with mothering responsibilities who are also in employment, often need to overcome considerable challenges in order to complete the course requirements; challenges which often result in extensive emotional pain. Using methods of photo‐elicitation and blogging, The Plastic Ceiling Project aimed to create a platform for mothers that worked and studied to discuss this emotional pain, allowing participants to highlight and discuss commonalities within their experiences. Rather than aiming to ‘solve’ problems for participants, this methodology aimed to empower individuals by allowing them to create a shared reality together, co‐create knowledge and to give them a vehicle to discuss and resolve difficulties and challenges collectively. This article considers how an arts‐based approach to research may have contributed to achieving those aims. 相似文献
35.
Neeldhara Misra 《Resonance》2008,13(7):662-679
In this section of Resonance, we invite readers to pose questions likely to be raised in a classroom situation. We may suggest strategies for dealing
with them, or invite responses, or both. “Classroom” is equally a forum for raising broader issues and sharing personal experiences
and viewpoints on matters related to teaching and learning science. 相似文献
36.
Anand K. Pyati Basavaraj B. Devaranavadagi Sanjeev L. Sajjannar Shashikant V. Nikam Mohd. Shannawaz Satish Patil 《Indian journal of clinical biochemistry : IJCB》2016,31(4):439-445
The study aimed to investigate whether heart-type fatty acid binding protein (H-FABP) measurement provides additional diagnostic value to that of conventional cardiac markers in acute myocardial infarction (AMI) within first 6 h after the onset of symptoms. The study included 120 subjects: 60 AMI cases and 60 age and sex matched controls. The cases and controls were further divided into 2 subgroups depending on the time since onset of chest pain as (1) subjects within 3 h and (2) between 3 and 6 h of onset of chest pain. In all the cases and controls, serum H-FABP concentration was measured by Immunoturbidimetric method, serum Troponin I and myoglobin concentrations by Chemiluminescence immunoassay and serum CK-MB concentration by Immuno-inhibition method. The sensitivity, specificity, positive and negative predictive values of H-FABP were significantly greater than CK-MB and myoglobin but were lesser than Troponin I in patients with suspected AMI in both within 3 h and 3–6 h groups. Receiver operating characteristic curves demonstrated greatest diagnostic ability for Troponin I (AUC = 0.99, p < 0.001) followed by H-FABP (AUC = 0.906, p < 0.001) within 3 h and 3–6 h after the onset of chest pain. In conclusion, the diagnostic value of H-FABP is greater than CK-MB and myoglobin but slightly lesser than troponin I for the early diagnosis of AMI within first 6 h of chest pain. H-FABP can be used as an additional diagnostic tool for the early diagnosis of AMI along with troponin I. 相似文献
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Shailja Misra Bhattacharya K. Tyagi R. K. Chatterjee 《Indian journal of clinical biochemistry : IJCB》1997,12(1):35-39
Thyroid antibodies are commonly utilized in the assessment and diagnosis of autoimmune thyroid disorders. We compared the
measurements of antithyroglobulin and antithyroidperoxidase antibodies by enzyme immunoassay with that of the conventional
agglutination method. This fully automated enzyme immunoassay is more specific and cost effective than the agglutination method.
Further this is a very quantitative and rapid method producing results in two hours as compared to at least twenty=four hours
required by the conventional method. Antithyroidperoxidase antibodies determined by enzyme immunoassay are more specific and
sensitive in the diagnosis of Hashimoto's thyroiditis than the antithyroglobulin antibodies. 相似文献
38.
D. K. Srivastava S. Kumar A. P. Misra 《Indian journal of clinical biochemistry : IJCB》1992,7(1):19-21
A 24 week follow-up study on lipid change following maintenance haemodialysis (MHD) in 25 chronic renal failure (CRF) patients
revealed significantly raised serum Triacylglycerol (TAG) levels in these cases (P<0.001), while cholesterol and HDL-Cholesterol
did not show any significant change, the extent of increase was 10.5±3.6% after 12 weeks and 23.0±5.8% after 24 weeks. Corresponding
increase in CRF patients treated conservatively, without haemodialysis, were 3.1±1.2% and 7.2±2.7% at these intervals. Subsequent
oral administration of L-Carnitine (5mg/kg body weight twice a day) for three weeks brought about a significant reversal of
elevated serum TAG level in MDH group as well as in the conservatively treated group (P≤0.05).
It is concluded that the haemodialysis induced Hyper-Triacylglycerolemia of CRF patients is revertible by Carnitine replenishment.
Even the concomitant increase in conservatively treated group is revertible by carnitine administration. 相似文献
39.
Vivek K. Dwivedi Mahesh Chandra P. C. Misra M. K. Misra 《Indian journal of clinical biochemistry : IJCB》2005,20(1):21-25
Effect of administration of 600 mg. vitamin E each day, for six days, was observed on activity of some of the anti-oxidant
enzymes and levels of malondialdehyde (as an index of free radical mediated damage) in the platelets of patients reperfused
after myocardial infarction. It has been found that vitamin E administration significantly lowers the level of malondialdehyde
in the patients. Vitamin E administration increases the activities of anti oxidant enzymes (viz. superoxide dismutase, glutathione
reductase and catalase) tested both in the patients and healthy controls. Vitamin E administration causes general stimulation
of anti-oxidant enzyme activities both in healthy persons and the patients, however, lowering of lipid per-oxidation upon
administration of vitamin E is specific for patients. These findings exhibit beneficial role of vitamin E administration in
the management of the patients reperfused after myocardial infarction. 相似文献
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