Search result diversification on attributed networks via nonnegative matrix factorization     

Zaiqiao Meng  Hong Shen  Huimin Huang  Wei Liu  Jing Wang  Arun Kumar Sangaiah 《Information processing & management》2018,54(6):1277-1291

Search result diversification is an effective way to tackle query ambiguity and enhance result novelty. In the context of large information networks, diversifying search result is also critical for further design of applications such as link prediction and citation recommendation. In previous work, this problem has mainly been tackled in a way of implicit query intent. To further enhance the performance on attributed networks, we propose a novel search result diversification approach via nonnegative matrix factorization. Our approach encodes latent query intents as well as nodes as representation vectors by a novel nonnegative matrix factorization model, and the diversity of the results accounts for the query relevance and the novelty w.r.t. these vectors. To learn the representation vectors of nodes, we derive the multiplicative updating rules to train the nonnegative matrix factorization model. We perform a comprehensive evaluation on our approach with various baselines. The results show the effectiveness of our proposed solution, and verify that attributes do help improve diversification performance.  相似文献   

Development and validation of Mobile Learning Acceptance Measure     

Sujeet Kumar Sharma  Mohamed Sarrab  Hafedh Al-Shihi 《Interactive Learning Environments》2017,25(7):847-858

The growth of Smartphone usage, increased acceptance of electronic learning (E-learning), the availability of high reliability mobile networks and need for flexibility in learning have resulted in the growth of mobile learning (M-learning). This has led to a tremendous interest in the acceptance behaviors related to M-learning users among the information systems researchers. Despite a large amount of significant research in the field of M-learning, the measurement of user acceptance of M-learning has not received attention. This research study intends to develop and validate a survey that measures users’ acceptance of M-learning. A total sample of 806 university and higher college students from different institutes in Oman participated in this study. This research study was conducted in two stages. The first stage using a sample size of 388 students initiated a generic questionnaire, and examined factorial validity and reliability. The second stage that was conducted using different sample of 418 students employed confirmatory factor analysis to establish factorial validity and measurement invariance. A correlated six-factor model (Flexibility, Suitability, Enjoyment, Efficiency, Economic and Social) was fit using maximum likelihood estimation. The internal consistency and item reliability of Mobile Learning Acceptance Measure was found to be at acceptable level for both samples.  相似文献   

Investigation of structures similarity of organic substances     

Ajay Kumar 《Resonance》2011,16(1):61-64

According to similarity property principle, structurally similar molecules tend to have similar properties. Similar molecules exhibit similar biological activities. However, there is no hard and fast rule that the compounds with similar chemical structure will have similar functions. There are several compounds of similar chemical structure with significantly different biological actions and activities. Structure similarity of natural products can be investigated using Tanimoto coefficient and Euclidean distance measurements. To do this, the molecules are decomposed into smaller fragments, and a dictionary, of the fragments are prepared. Using the dictionary, 2D fingerprints are formed. With the fingerprints Tanimoto coefficient and Euclidean distance are quantitated.  相似文献   

The impact of supplier bargaining power on the advertising costs of movie sequels     

Judy Ma  Dongling Huang  M. V. Shyam Kumar  Andrei Strijnev 《Journal of Cultural Economics》2015,39(1):43-64

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Stress,Oxidative Injury and Disease     

Kaushal K. Srivastava  Ratan Kumar 《Indian journal of clinical biochemistry : IJCB》2015,30(1):3-10

The living system on earth is largely using oxygen for burning metabolic fuel for energy. The toxicity of oxygen is largely due to the formation of free radicals in living systems. Stress is also responsible for the generation of free radicals. The evidence for the involvement of free radicals and oxidative injury in producing metabolic disturbance, maladjustment and many diseases has been accumulating since long. It is largely believed that the root cause of many chronic diseases is stress induced free radicals and resultant oxidative injury.  相似文献   

Aggravation of Inflammation by Smokeless Tobacco in Comparison of Smoked Tobacco     

Shailendra Dwivedi  Apul Goel  Sanjay Khattri  Praveen Sharma  Kamlesh Kumar Pant 《Indian journal of clinical biochemistry : IJCB》2015,30(1):117-119

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Antidyslipidemic Effect of Ocimum sanctum Leaf Extract in Streptozotocin Induced Diabetic Rats     

Ishrat Husain  Ramesh Chander  Jitendra Kumar Saxena  Abbas Ali Mahdi  Farzana Mahdi 《Indian journal of clinical biochemistry : IJCB》2015,30(1):72-77

The antidyslipidemic activity of Ocimum sanctum leaf extract was studied in streptozotocin induced diabetic rats. In this model, there was significant increase in plasma markers of diabetic-dyslipidemia following diminution of lipid metabolizing enzymes. Oral administration of leaf extract (500 mg/kg b.w.p.o.) for 15 days resulted in significant decrease in diabetogenic and dyslipidemia parameters; namely blood glucose, glycosylated hemoglobin, lipid peroxide, free fatty acids, small dense low density lipoprotein, lipid and protein components of plasma lipoproteins, adipose and liver. The regulation of lipids was accompanied by stimulation of postheparin lipolytic activity, reactivation of lecithin cholesterol acyl transferase and hepatic lipoprotein lipase enzymes. The results of the present study demonstrated antidyslipidemic and antioxidant activities in leaf extract of O. sanctum which could be used in prevention of diabetic-dyslipidemia and related complications.  相似文献   

Comparative Study of Serum Amylase and Lipase in Acute Pancreatitis Patients     

HS Batra  Ashwini Kumar  TK Saha  Pratibha Misra  Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2015,30(2):230-233

To establish utility of single enzymatic marker for the diagnosis of acute pancreatitis. This is a cohort study. Tertiary care centre proven cases of acute pancreatitis (n = 50) admitted in surgery ward between December 2011 and May 2013 were included in the study. Serum amylase and lipase were performed along with many analytes. All relevant data including serum lab values and imaging were collected. All 50 patients included in the study had raised serum lipase, 42 patients had both amylase and lipase raised, 8 patients had amylase normal but lipase raised. In smaller hospitals where limited lab and radiological facilities are available, estimation of serum lipase will be a better choice over serum amylase in diagnosis of acute pancreatitis.  相似文献   

Purification and Characterization of an Endoinulinase from Xanthomonas campestris pv. phaseoli KM 24 Mutant     

Kameshnee Naidoo  Ajit Kumar  Vikas Sharma  Kugen Permaul  Suren Singh 《Food Technology and Biotechnology》2015,53(2):146-153

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Demonstration of a new biosensing concept for immunodiagnostic applications based on change in surface conductance of antibodies after biomolecular interactions     

Vashist SK  Kaur I  Bajpai RP  Bharadwaj LM  Tewari R  Raiteri R 《Journal of Zhejiang University. Science. B》2006,7(9):683-685

We report an important observation that the surface conductivity of antibody layer immobilized on polylysine-coated glass substrate decreases upon the formation of complex with their specific antigens. This change in conductivity has been observed for both monoclonal and polyclonal antibodies. The conductance of monoclonal mouse IgG immobilized on polylysine-coated glass substrate changed from 1.02×10⁻⁸ Ω⁻¹ to 1.41×10⁻¹¹ Ω⁻¹ at 10 V when complex is formed due to the specific biomolecular interactions with rabbit anti-mouse IgG F(ab′)₂. Similar behavior was observed when the same set up was tested in two clinical assays: (1) anti-Leishmania antigen polyclonal antibodies taken from Kala Azar positive patient serum interacting with Leishmania promastigote antigen, and (2) anti-p21 polyclonal antibodies interacting with p21 antigen. The proposed concept can represent a new immunodiagnostic technique and may have wide ranging applications in biosensors and nanobiotechnology too.  相似文献