Electricity     

D. P. Sen Gupta 《Resonance》1997,2(9):38-47

The experiments of Michael Faraday and Joseph Henry in electromagnetic induction ushered in the era of electricity during the late nineteenth century. Human civilization has undergone a total change since then. This paper in two parts describes the basic principles of AC power generation, its transmission and distribution.  相似文献   

Acute and chronic toxicity studies on partially purified hypoglycemic preparation from water extract of bark ofFicus bengalensis     

S. Gupta  R. Shukla  K. M. Prabhu  S. Aggrawal  U. Rusia  P. S. Murthy 《Indian journal of clinical biochemistry : IJCB》2002,17(1):58-63

Acute and chronic toxicity studies were conducted to assess toxicity of a partially purified preparation from the water extract of the bark ofFicus bengalensis, which was demonstrated in our earlier studies to have significant hypoglycemic and hypocholesteroiemic effect on alloxan induced, mild and severe diabetes in rabbits. LD₅₀ of this preparation was found to be ∼1 gm/kg in rats when given orally. For chronic toxicity studies 3 doses of aqueous preparation were given to 3 groups of rats. First group received 5 times ED₅₀ (50 mg/kg), second group 10 times ED₅₀ (100 mg/kg) and the third group 15 times ED₅₀ (150 mg/kg) for 3 months. Fourth group which served as control was given water. After three months, blood was collected for studying biochemical and hematological parameters. Blood glucose, serum cholesterol, liver and kidney function tests, haemoglobin, total and differential leukocyte count were determined. Animals were sacrificed and histopathological examination of liver, heart and kidneys was carried out. Results of the study showed that partially purified preparation fromFicus bengalensis is not toxic by all the above mentioned parameters.  相似文献   

Serodiagnosis of tuberculosis using two ELISA systems     

Swati Banerjee  Sonika Gupta  Niraj Shende  Satish Kumar  Bhaskar C. Harinath 《Indian journal of clinical biochemistry : IJCB》2003,18(2):48-53

Serodiagnosis by ELISA has been widely explored over the years, in the diagnosis of tuberculosis. Two ELISA systems were evaluated for detection of mycobacterial antibodies in pulmonary and extra pulmonary tuberculosis. The two test assays explored were ERBA LISA (TB IgG) test (Anda Biologicals) which uses A60 antigen complex found in the cytosol of typical and atypical mycobacteria, and SEVA TB (IgG) ELISA, which uses a 31 kDa, glycoprotein antigen purified fromM. tb H₃₇Ra culture filtrate. Sera from 98 proven tuberculosis [pulmonary TB (48), tuberculous lymphadenopathy (30), tuberculous meningitis (15) & genitourinary TB (5)] were studied along with 32 healthy controls. The overall positivity obtained using ERBA LISA (TB IgG) test and SEVA TB (IgG) ELISA test was 72.9% and 91.6% in pulmonary tuberculosis, 43.3% and 76.6% in tuberculous lymphadenopathy respectively. The sensitivity of ERBA LISA test in tuberculous meningitis and genito-urinary TB was significantly low (26.6% & 40% respectively) compared to sensitivity obtained using SEVA TB ELISA (86.6% & 60% respectively) with overall specificity of 60% and 87.5%. Thus SEVA TB IgG ELISA test was found to be more sensitive than ERBA LISA in detecting IgG antibodies in tuberculous sera, in particular in extra pulmonary tuberculosis cases.  相似文献   

Metabolic Issues in Schizophrenic Patients Receiving Antipsychotic Treatment     

Aditi Gupta  Gora Dadheech  Dharamveer Yadav  Praveen Sharma  Shiv Gautam 《Indian journal of clinical biochemistry : IJCB》2014,29(2):196-201

Schizophrenia is a psychotic disorder with a complex pathophysiology and requires treatment that includes long term administration of antipsychotics that is said to be associated with metabolic syndrome. This study was designed to evaluate the impact of seven different antipsychotics prescribed to schizophrenic patients, on development of metabolic syndrome in the patients. A total of 210 patients with schizophrenia (30 patients in each drug therapy group) were recruited according to ICD-10 criteria and were assigned to receive the drug for 16 weeks. Measurement of anthropometric (body weight, waist circumference, blood pressure) and biochemical parameters (glucose, insulin, HOMA-IR, triglycerides, LDL, HDL) was done and the patients were subjected to ATP-III defined criteria for metabolic syndrome. Patients undergoing treatment with olanzapine were more prone to metabolic syndrome as the drug induces weight gain after 16 weeks of treatment. It also induces dyslipidemia (P < 0.001) and hyperglycemia (P < 0.01). Clozapine was found to be second most potent drug in inducing metabolic syndrome as the weight in clozapine treated patients increased after 16 weeks, along with a significant increase in glycemic (P < 0.001) and lipid parameters (P < 0.01). Aripriazole and amisulphride are comparatively safer drugs as their role in inducing metabolic abnormalities in schizophrenic patients was insignificant, although the impact of long term administration of these drugs needs to be explored. It is clear from the study that antipsychotic treatment induces metabolic syndrome so, it becomes important that the metabolic and cardiovascular risk factors should be surveillance regularly in schizophrenic patients undergoing antipsychotic treatment.  相似文献   

Learning Efficiency Versus Low IQ and/or Teachers’ Ratings as Predictors of Reading Ability of ‘Mentally Defective’ Children: a longitudinal study 1     

R. M. Gupta 《Educational studies》1985,11(2):109-118

The major thrust of this study was to test the hypothesis that some of the conventional assessment procedures are not necessarily valid indexes of learning efficiency of children whose tested abilities fall in the ‘mentally defective’ range. The sample of the longitudinal study consisted of 27 second year Junior children, of which six were English and twenty one Asian children. All these children were given the Coloured Progressive Matrices, Draw‐a‐Man test, Schonell Graded Word Recognition Test and the author designed Learning Efficiency Test Battery. The results quite clearly suggest that the information about these children's learning efficiency as measured by the Learning Efficiency Test Battery is more useful for predicting reading and definitely better for predicting changes in reading levels over a period of time than the conventinal type of assessment. It is concluded that the low IQ, should not be deemed as an index of poor learning ability.

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Heterogeneous middle-class and disparate educational advantage: parental investment in their children’s schooling in Dehradun,India     

Achala Gupta 《British Journal of Sociology of Education》2020,41(1):48-63

Abstract

The heterogeneity of the contemporary Indian middle-class has been discussed widely. However, the effect of its internal differences on the distribution of educational resources needs to be examined systematically. Drawing upon in-depth interviews with parents in 53 middle-class families in Dehradun, India, this paper explores three aspects of the home-school relationship: how socioeconomic transformations shape parents’ aspirations for their children’s future, educational decisions parents make to realise those aspirations, and mothers’ engagement in their children’s everyday schooling. The tripartite analysis reveals that despite sharing common educational goals and strategies with the population in general, middle-class families in India use their class privilege to gain valuable educational resources. The paper argues that the discrepancy in the mobilisation of accumulated resources in the heterogeneous middle-class results in disparate educational advantages across families. It critiques the binary construction of social classes when explaining the processes of social reproduction in contemporary Indian society.  相似文献   

Technology-supported learning environments in science classrooms in India     

Adit Gupta  Darrell Fisher 《Learning Environments Research》2012,15(2):195-216

The adoption of technology has created a major impact in the field of education at all levels. Technology-supported classroom learning environments, involving modern information and communication technologies, are also entering the Indian educational system in general and the schools in Jammu region (Jammu & Kashmir State, India) in particular. This study, which is the first of its kind in India, reports the use of a modified form of Technology-Rich Outcomes-Focused Learning Environment Inventory (TROFLEI) for assessing students?? perceptions of their learning environments in technology-supported science classrooms. Analysis of data from 705 students from 15 classes provided evidence for the reliability and validity of the questionnaire in Indian science classroom settings. The same data also were used for studying gender differences and associations between students?? perceptions of their technology-supported learning environments and three learner outcomes (attitude towards science, academic efficacy and academic achievement).  相似文献   

Immunobiology of trophoblast cells     

Chandana Das  V. Senthil Kumar  Sayantani Basak  Surabhi Gupta  Sunesh Kumar 《Indian journal of clinical biochemistry : IJCB》2000,15(1):60-62

A female patient who had two primary cancers was investigated. Biochemical analysis of patient's serum for different parameters indicated an alteration in the metabolic process. Prognostically, the patient has shown favourable clinical features.  相似文献   

Antitubercular activity of garlic (allium sativum) extract on combination with conventional antitubercular drugs in tubercular lymphadenitis     

R. L. Gupta  Sundeep Jain  V. Talwar  H. C. Gupta  P. S. Murthy 《Indian journal of clinical biochemistry : IJCB》1999,14(1):12-18

Based on our demonstration earlier that ethanol extract, water extract and a compound purified from garlic possessedin vitro antitubercular activity against drug resistant and susceptibleMycobacterium tuberculosis, we tried the effect of garlic extract in 30 patients of tubercular lymphadenitis. For ethical considerations, two groups of patients, 30 each, were given antitubercular therapy (ATT) consisting of isoniazid, rifampicin, ethambutol and pyrazinamide for 30 days. For the next 15 days (31 to 45 days) group 1 patients received 3–6 garlic pearls per day in addition to ATT while group 2 patients received ATT only. From 46th day onwards both the groups received ATT only for 6–8 months. Antitubercular activity of the serum samples collected on 45th day was assessed by its effect on the growth ofM. tuberculois. The serum of group 1 patients showed significantly much higher antitubercular activity than that of group 2 patients. Further, there was relief of dyspeptic symptoms caused by ATT therapy in patients of group 1 with garlic plus ATT therapy but no change in group 2 patients with ATT only. Liver function and hematological tests were normal in both the groups after 6 months of therapy. Garlic extracts or compounds have a good potential as antitubercular(s) drug if given as a supplement to ATT.  相似文献   

On training to facilitate re-engineering     

Kavita Gupta 《Performance Improvement》1995,34(5):28-32

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