Trajectory-based real-time control of an electrical circuit against unknown faults     

Tushar Jain  Joseph J. Yamé  Dominique Sauter 《Journal of The Franklin Institute》2014

This paper presents a trajectory-based online control reconfiguration mechanism against unknown fault occurring in an electric circuit. First, we demonstrate the modeling of an electric circuit by taking the time-trajectory viewpoint, where no a priori input–output partition has been made. The uniqueness of this viewpoint lies in the fact that it deals only with variables that describe the system without any dedicated (external or internal -type) representation. Subsequently, we illustrate a novel real-time fault-tolerant control (FTC) strategy based on this trajectory standpoint, which does not require an explicit model-based fault diagnosis unit. Instead, the controller is reconfigured directly based on the trajectories generated by the system in real-time, and the given control specifications. In this way, we efficiently excrete the shortcomings that are often seen in model-based fault-tolerant systems. The proposed FTC method is effectively demonstrated on an RLC circuit.  相似文献   

C-Reactive Protein and Uric Acid Levels in Patients with Psoriasis     

Isha  Jain VK  Lal H 《Indian journal of clinical biochemistry : IJCB》2011,26(3):309-311

Serum CRP and uric acid levels were estimated in twenty-five patients with psoriasis (group III) before and after 12 weeks of treatment. Results were compared with a group of 25 normal subjects (group I) and a group of 25 patients of various skin diseases other than psoriatic lesion (group II). Mean value for CRP was found to be increased by more than 20 folds in patients with psoriasis, which was subsequently reduced to nearly 50% of the initial value after 12 weeks of treatment. These patients also showed hyperuricemia. Nearly 25% of these patients also exhibited arthritis. It is thus suggested that both CRP and uric acid levels should be monitored in patients with psoriasis.  相似文献   

Extra Pulmonary Tuberculosis: A Diagnostic Dilemma     

Jain A 《Indian journal of clinical biochemistry : IJCB》2011,26(3):269-273

Tuberculosis remains a major public health problem globally, with India being one of the high burden countries. The common causative agent is Mycobacterium tuberculosis but in developing countries M. bovis is reported as a potential human pathogen. Almost 20% of all reported cases of tuberculosis are of extra pulmonary form of disease. Diagnosis of extra pulmonary tuberculosis (EPTB) is not always possible with conventional methods, due to the long time required and the paucibacillary nature of samples; hence the need of rapid molecular methods. A prospective study was conducted on 300 patients of EPTB over a period of 5 years. These patients were suspected cases of tubercular meningitis, tubercular ascites and tubercular lymphadenitis. Samples analyzed were cerebrospinal fluid, ascitic fluid and lymph node fine needle aspirate. A two step PCR targeting hup B gene was used. Clinical response to anti tubercular therapy (ATT) was taken as positive (gold standard). PCR for hup B gene was positive in 147 samples out of 155 ATT responders. Of these 85.71% were infected with M. tuberculosis, 9.52% with M. bovis alone and 4.76% showed co infection with both M.tb and M. bovis. The sensitivity and specificity of PCR was 90.32 and 94.48% respectively.  相似文献   

Effect of Lecithin on <Emphasis Type="SmallCaps">d</Emphasis>-Galactosamine Induced Hepatotoxicity Through Mitochondrial Pathway Involving Bcl-2 and Bax     

P. Vasanth Raj  K. Nitesh  Jain Prateek  M. Neena Sankhe  J. Venkata Rao  C. Mallikarjuna Rao  N. Udupa 《Indian journal of clinical biochemistry : IJCB》2011,26(4):378-384

Twenty four Wistar strain albino rats were used for the investigations. Lecithin 50 and 100 mg/kg b wt was administered for 1 week by oral route. Liver damage was induced by intra peritoneal administration of 400 mg/kg b wt d-galactosamine on the last day. At the end of the study animals were sacrificed and liver enzyme levels, histopathology, mitochondrial integrity, expression of p53, Bax and Bcl-2 mRNA levels were studied. Increases in the liver enzyme levels by d-GalN were significantly inhibited by pretreatment with lecithin. Histopathological observation further confirmed the hepatoprotective effect of lecithin. In addition, the disruption of mitochondrial membrane, up regulation of Bax and down regulation of Bcl-2 mRNA levels in the liver of d-GalN intoxicated rats were effectively prevented by pretreatment with lecithin. The results of the present study validate our conviction that d-GalN causes hepatic damage via mitochondrial pathway involving Bax and Bcl-2.  相似文献   

Effect of immobilisation stress on lipid peroxidation and lipid profile in rabbits     

Hem Lata  G. K. Ahuja  A. P. S. Narang  Lily Walia 《Indian journal of clinical biochemistry : IJCB》2004,19(2):1-4

Stress is one of the basic factors in the aetiology of a number of diseases such as atherosclerosis, coronary heart disease, aging, liver disease etc. Hence this work was designed to study the effect of stress in the form of forced immobilisation stress on lipid peroxidation and lipid profile in rabbits. The study was conducted in 25 healthy rabbits of either sex. Rabbits were subjected to forced immobilisation for two hours everyday for consecutive seven days. Blood samples were collected on day 1, 3 and 7 after immobilisation period. Malondialdehyde (MDA), a marker of lipid peroxidation was estimated by TBA assay method. Lipid profile was analysed by multichannel autoanalyser. There was statistically significant increase in MDA, total cholesterol, LDL, VLDL and triglycerides with immobilisation. These findings indicate that stress in the form of forced immobilisation increases lipid peroxidation and alter lipid profile, which may be responsible for pathophysiology of various diseases.  相似文献   

Serum and tissue levels of zinc,copper, magnesium and retinol in prostatic neoplasms     

M. Jain  Kavita Sharma  V. P. Sharma 《Indian journal of clinical biochemistry : IJCB》1994,9(2):106-108

Zinc (Zn), copper (Cu), magnesium (Mg) and retinol levels were studied in serum and tissue of the patients with prostatic carcinoma (Ca), benign hyperplasia (BHP) and control subjects. Zinc and retinol levels were low in both serum and tissues of patients with carcinoma, while in BHP, both zinc and retinol level were decreased. Copper levels were high in serum and tissues of both BHP as well as carcinoma patients. Magnesium levels were elevated in both serum and tissues of cancerous patients. The results indicate that Zn, Cu, and Mg metabolism is disturbed in malignancy.  相似文献   

Augmented reflective learning and knowledge retention perceived among students in classrooms involving virtual laboratories     

Krishnashree Achuthan  Saneesh P. Francis  Shyam Diwakar 《Education and Information Technologies》2017,22(6):2825-2855

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Effect of yoga training on plasma lipid profile,R.B.C. membrane lipid peroxidation and Na+K+ ATPase activity in patients of essential hypertension     

B. Talukdar  S. Verma  S. C. Jain  M. Majumdar 《Indian journal of clinical biochemistry : IJCB》1996,11(2):129-133

We conducted a controlled study on effect of selected yoga practive in the control and management of 50 cases of essential hypertension and equal number of healthy (nonhypertensive) controls. Free radical cellular damage is considered to be the underlying common biological factor in essential hypertension. We, therefore, investigated lipid profile lipid peroxidation and Na⁺K⁺ ATPase activities of plasma membrane of subjects with essential hypertension. It was found that hypertensive subjects had an elevated lipid peroxidation and decreased Na⁺K⁺ ATPase activity in plasma membrane as compared to normotensive healthy controls, the specific yoga training protocol which was administered not only helped to decrease blood pressure but also retard the progression of ceellular damage due to free radicals.  相似文献   

Crossing a nonlinear resonance     

Sudhir R. Jain 《Resonance》2014,19(9):797-813

The idea of adiabatic invariance is presented in the context of simple classical mechanical models. The adiabatic invariant jumps across the separatrix — an attempt has been made to bring out the basic ideas underlying the Melnikov-Arnold integral. This becomes important as soon as a perturbation to a regular, stable system makes it dynamically unstable.  相似文献   

Education and sustainability: paradigms,policies, and practices in Asia,edited by Michelle Y. Merill,Patricia Burkhardt-Holm,Chew-Hung Chang,Md Saidul Islam,and Youngho Chang. Abingdon,Routledge (2018).     

Shyam Anand Singh  Andy Wi 《Environmental Education Research》2019,25(10):1584-1586

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