Evaluation of the Role of Routine Laboratory Biomarkers in COVID-19 Patients: Perspective from a Tertiary Care Hospital in India     

Barnali Das  Seema Y. Bhatia  Poonam M. Pal 《Indian journal of clinical biochemistry : IJCB》2021,36(4):473

  相似文献   

Mediated subjectivities of the maternal: A critique of childbirth videos on YouTube     

Ranjana Das 《The Communication Review》2018,21(1):66-84

  相似文献   

Teaching chemistry through riddles     

Mala?Das SharmaEmail author 《Resonance》2004,9(7):74-76

  相似文献   

Diagnostic Role of Tumour Markers CEA, CA15-3, CA19-9 and CA125 in Lung Cancer     

Indranath Ghosh  Debojyoti Bhattacharjee  Anjan Kumar Das  Goutam Chakrabarti  Anindya Dasgupta  Subir Kumar Dey 《Indian journal of clinical biochemistry : IJCB》2013,28(1):24-29

The aim of this study was to assess the diagnostic yield of the tumour markers carcinoembryonic antigen, carbohydrate antigen 15-3, carbohydrate antigen 19-9 and carbohydrate antigen 125, in serum and bronchoalveolar lavage fluid in a group of patients with bronchogenic carcinoma. Serum and bronchoalveolar lavage fluid samples were collected in a group of 90 patients with benign or malignant pulmonary diseases. After appropriate processing, tumour markers were determined by enzyme immunoassay. The diagnostic yields (sensitivity, specificity and predictive values) in each environment (serum and bronchoalveolar lavage fluid) were obtained by using "Receivers operating characteristic" curve. Determined individually, carcinoembryonic antigen, carbohydrate antigen 19-9 and carbohydrate antigen 125, showed the greatest diagnostic accuracy in bronchoalveolar lavage fluid. Carbohydrate antigen 15-3 did so in serum. Carcinoembryonic antigen was the most relevant marker in bronchoalveolar lavage fluid. For the factors evaluated in this study, determination of carcinoembryonic antigen, carbohydrate antigen 19-9 and carbohydrate antigen 125 in bronchoalveolar lavage fluid were clinically more useful markers in comparison with serum, although the latter may also be helpful in certain situations. Although there is no specific tumour marker for lung cancer, the combination of several can be used to diagnose most patients with lung cancer and also to rule out false positive and negative cases.  相似文献   

Effect of insulin on serum lipids in relation to nutritional status in diabetics     

G. P. Das  B. Mandal  P. Ghosh  C. R. Maity 《Indian journal of clinical biochemistry : IJCB》1993,8(1):39-43

Serum levels of cholesterol, triglyceride, free fatty acid (FFA) and high density lipoprotein (HDL) cholesterol were studied in 10 undernourished and 10 better nourished diabetic patients at different periods of insulin treatment and in non-diabetic controls. Serum concentrations of cholesterol, triglyceride and FFA were significantly higher in untreated diabetic patients than in control but the elevated lipid levels gradually shifted towards normal on insulin treatment. The HDL cholesterol, on the other hand, was significantly lower in untreated diabetic subjects than those in controls and the HDL cholesterol also gradually modified on insulin therapy. However, the improvement of all the lipid parameters on insulin treatment was somewhat delayed in undernourished compared to those of better nourished diabetics. These results, therefore, suggest that malnutrition interferes with the serum lipid improvement in diabetics on insulin treatment and may make them more prone to develop vascular complications.  相似文献   

Impact of iodine deficiency on thyroid function in pregnant African women — A possible factor in the genesis of ‘small for dates’ babies     

Santosh C. Das  Uche P. Isichei  Aminu Z. Mohammed  Abraham A. Otokwula  Abiodun Emokpae 《Indian journal of clinical biochemistry : IJCB》2005,20(2):35-42

The effect of iodine deficiency (ID) on thyroid function in African women during pregnancy and postnatal period was examined, for which very limited information is available. Serum T₄, T₃, TSH, TBG, thyroxine binding capacity (TBK), free thyroxine index (FT₄I=T₄/TBK) and T₄/TBG were determined by ELISA technique in 32 pregnant women (resident of Plateau state, Nigeria- an ID zone) through pregnancy upto term delivery, and in 5 women up to 6 weeks post delivery. Urinary iodide level was measured at delivery to determine the degree of iodine deficiency. Results were matched with a non pregnant control comprising 44 subjects. 5555 birth weights (BW) of term babies in the region were analysed to determine the prevalence of ‘small for dates’ (SFD) babies in the population. Results show that the level of serum FT₄I was elevated very significantly at late gestation (P<.001) but the women were not hyperthyroid, suggesting a marked disturbance in binding of T₄ with TBG during pregnancy. Five women with SFD babies were found in ‘compensated hypothyroid state’ and showed a significant depression (p<.01) in serum T₄/TBG, T₄, FT₄I and T₃ levels to a low normal range, with a concurrent significant rise (p.<.001) in TSH level (above normal range) throughout pregnancy. Incidence of SFD babies was higher (p.<.001) in ID zone (Bassa 15.2%) compared to control zone (Jos 9.8%). It is concluded that a state of maternal ‘subclinical (compensated) hypothyroidism’ during pregnancy possibly plays an important role in the aetiopathogenesis of SFD babies in Africans. A normal reference range for thyroid parameters at various stages of pregnancy in healthy African women is established for the first time.  相似文献   

Ghanaian teachers: competencies perceived as important for inclusive education     

Ahmed Bawa Kuyini  Kofi Asiama Yeboah  Ajay Kumar Das  Awal Mohammed Alhassan  Boitumelo Mangope 《International Journal of Inclusive Education》2016,20(10):1009-1023

  相似文献   

Building Vocabulary Knowledge in Preschoolers Through Shared Book Reading and Gameplay     

Brenna Hassinger‐Das  Katherine Ridge  Amira Parker  Roberta Michnick Golinkoff  Kathy Hirsh‐Pasek  David K. Dickinson 《Mind, Brain, and Education》2016,10(2):71-80

This study moves beyond previous investigations to examine whether an educational intervention combining shared book reading with a vocabulary game increases children's vocabulary knowledge. Four‐year‐olds (N = 44) were randomly assigned to dyads in either an intervention (shared book reading plus vocabulary review game) or comparison condition (shared book reading, after‐reading vocabulary review, and game that did not teach vocabulary). After two 30‐min sessions, results demonstrated that the intervention condition outperformed the comparison condition on measures of receptive and expressive knowledge of taught vocabulary words. Children in the intervention group who scored the lowest at pretest on the receptive measure saw the most gains in taught word knowledge. Findings suggest that combining vocabulary gameplay with shared book reading improved children's learning of the vocabulary words in comparison to a comparison group.  相似文献   

And Baby Makes Four: Predictors of Attachment Security among Preschool-Age Firstborns during the Transition to Siblinghood     

Douglas M. Teti  Julie Wolfe Sakin  Elizabeth Kucera  Kathleen M. Corns  Rina Das Eiden 《Child development》1996,67(2):579-596

The present study examined preschool-age firstborns' adjustment to siblinghood, as indexed by security of firstborn-mother attachment, in a sample of 194 2-parent families. Security of firstborn attachment decreased significantly after a secondborn's birth, but the size of the decrease was smaller among firstborns under 24 months relative to 2–5-year-olds. Mothers' marital harmony and affective involvement with firstborns predicted firstborn security before and after the baby's birth, whereas mothers' psychiatric symptoms predicted firstborn security only after the birth. Post-hoc analyses of select subgroups revealed that mothers of firstborns with high security scores before the newborn's birth, regardless of whether scores remained high or dropped after the birth, showed higher levels of psychosocial and behavioral functioning than did mothers of firstborns with consistently low security scores at both time points. However, substantial drops in firstborn security after a secondborn's birth were associated with higher maternal psychiatric symptom scores both prior to and following the birth. Results suggest that quality of firstborn adjustment to siblinghood can be predicted from both structural and familial aspects of the firstborn environment.  相似文献   

Interaction ofLabeo rohita lectin (LRP) with mycobacterial surface oligosaccharide     

S. Mitra  H. R. Das 《Indian journal of clinical biochemistry : IJCB》2001,16(2):181-184

A C-type mannose specific lectin (LRP) isolated from plasma of fresh water fishLabeo rohita showed 500 times higher specificity towards cell surface oligosaccharide (LAM) ofMycobacterium tuberculosis (H37Rv). Using biotinylated LRP, binding between lectin and LAM was demonstrated by ELISA and it was observed that even 3ng of oligosaccharides might be detected using only 1μg of biotinylated lectin.  相似文献