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41.
Debye won the 1936 Nobel Prize in Chemistry for his contributions to molecular structure, dipole moment relationship and for
diffraction of X-rays and electrons. Electrochemists, however, remember him for the Debye-Hückel limiting law that describes
the behavior of strong electrolytes. In explaining the non-ideal behavior of strong electrolytes, his mathematical treatment
assumes that each ion is surrounded by an ionic cloud of oppositely charged ions, which retards the movement of ions in the
medium. The theory not only provides a method for calculation of activity coefficients, but has also helped, among other things,
in our understanding of diffusion in ionic media, change in the rate of ionic reactions upon addition of salts, and biochemical
reactions. 相似文献
42.
We present an electrokinetic framework for designing insulator constriction-based dielectrophoresis devices with enhanced ability to trap nanoscale biomolecules in physiological media of high conductivity, through coupling short-range dielectrophoresis forces with long-range electrothermal flow. While a 500-fold constriction enables field focusing sufficient to trap nanoscale biomolecules by dielectrophoresis, the extent of this high-field region is enhanced through coupling the constriction to an electrically floating sensor electrode at the constriction floor. However, the enhanced localized fields due to the constriction and enhanced current within saline media of high conductivity (1 S/m) cause a rise in temperature due to Joule heating, resulting in a hotspot region midway within the channel depth at the constriction center, with temperatures of ∼8°–10°K above the ambient. While the resulting vortices from electrothermal flow are directed away from the hotspot region to oppose dielectrophoretic trapping, they also cause a downward and inward flow towards the electrode edges at the constriction floor. This assists biomolecular trapping at the sensor electrode through enabling long-range fluid sampling as well as through localized stirring by fluid circulation in its vicinity. 相似文献
43.
Rashmi G. Shukla Anuja Agarwal Vidhu Shekhar 《The Journal of High Technology Management Research》2021,32(2):100415
Indian Healthcare system is a complex and distinguished structure due to variety of factors viz. population size it serves, presence of organized and unorganized services of healthcare, economic disparity and governance structure among others. Extant research emphasizes on the aspects like transparency, trust, disintermediation, non-repudiation, benchmarking of processes and practices, traceability and data integrity among others to stimulate the Indian Healthcare system for an improvised and more effective format. Blockchain Technology is recent innovation that offers many of these aforementioned aspects as a feature to the host systems. However, it is critical to understand and articulate the utility of Blockchain Technology specific to the Indian Healthcare system. Further, it is important to gauge the requirement elicitation of key stakeholders for Blockchain Technology adoption in Indian Healthcare system w.r.t any attribute prioritization/customization or design considerations (Consensus mechanism, type of blockchain, smart contracts etc.). There have been some research works on aspects of Blockchain applications in Indian Healthcare but lack a strong perspective of stakeholder requirements. We use Value-Focused Thinking framework based on discussions with the stakeholders to address the above mentioned research premise. We identify Fundamental Objectives and Strategic Objectives from the stakeholder interactions that contribute to the strategic goal. This is a niche work with a significant analytical contribution from the information systems perspective of Blockchain Technology adoption in the Indian Healthcare ecosystem given the light of premises from realms of human agents, behavioural and applications requirement from a stakeholder viewpoint. 相似文献
44.
A. K. Shukla 《Resonance》2006,11(7):42-50
The intensity of solar radiation in the Earth’s direction from the Sun is approximately 1353 kW/m2, a number also called the ‘solar constant’. Accordingly, it is estimated that Earth receives about 96 billion kilowatts from
the Sun each second. If this colossal and unlimited energy could be more fully utilized, our dependence on fast dwindling
fossil cache will be drastically reduced. Solar energy is available in various forms such as direct solar radiation, wind,
wave power, rain (in the form of hydropower), photosynthesis and ocean thermal gradients. Among these, the direct conversion
of sunlight into electricity is clean and attractive. This article highlights various routes to directly harness electricity
from sunlight.
An erratum to this article is available at . 相似文献
45.
Haseeb Akhtar Sharma Anita Shukla Prabhat Kumar 《Journal of Zhejiang University. Science. B》2005,6(8):736-742
Studies were conducted under pot conditions to determine the comparative efficacy of carbofuran at 1 mg a.i./kg soil, bavistin
at 1 mg a.i./kg soil, neem (Azadirachta indica) seed powder at 50 mg/kg soil, green mould (Trichoderma harzianum) at 50.0 ml/kg soil, rhizobacteria (Pseudomonas fluorescens) at 50.0 ml/kg soil against root-knot nematode,Meloidogyne incognita-wilt fungus,Fusarium oxysporum disease complex on green gram,Vigna radiata cv ML-1108. All the treatments significantly improved the growth of the plants as compared to untreated inoculated plants.
Analysis of data showed that carbofuran andA. indica seed powder increased plant growth and yield significantly more in comparison to bavistin andP. fluorescens. Carbofuran was highly effective against nematode, bavistin against fungus,A. indica seed powder against both the pathogens and both the bioagents were moderately effective against both the pathogens. 相似文献
46.
47.
Bhalla Kapil Shukla Rimi V. P. Gupta S. Pugazhenthi K. M. Prabhu 《Indian journal of clinical biochemistry : IJCB》1995,10(2):57-61
In the present study, 58 diabetic patients (type II) comprising uncomplicated (27) and complicated (31) cases along with 38 healthy matched controls were investigated for glycosylated hemoglobin (HbA1), glycosylated serum proteins (GSP) and serum lipid profile viz. triacylglycerol, total cholesterol, HDL-cholesterol (HDL-C), VLDL-C, LDL-C and their ratios. HbA1 and GSP were significantly elevated in diabetic group as a whole when compared with controls (p<0.01), but comparison of mean values of complicated and uncomplicated group revealed (though higher in complicated) that the difference between two groups was not statistically significant (p>0.05). Follow-up studies showed that while GSP levels reflect variations in blood glucose over a shorter period of 15 days, those of HbA1 do so for about 3 months. HbA1 correlated with fasting blood glucose (p<0.01), whereas GSP showed correlation with both fasting (p<0.01) and postprandial (p<0.05) blood glucose. Hypercholesterolemia and hypertriacylglycerolemia were observed (p<0.01) in both the groups. However no significant change was seen in HDL-C (p>0.05) even after accounting for sex in both the groups. Interestingly TC:HDL-C was elevated significantly (p<0.01) in the above groups. These findings seem to suggest that at the levels of hyperglycemia, hypercholesterolemia and hypertriacylglycerolemia observed, some patients are prone to develop complications earlier. 相似文献
48.
Shalini N. Maksane Sucheta P. Dandekar Akash Shukla Shobna Bhatia 《Indian journal of clinical biochemistry : IJCB》2016,31(1):108-116
The reference intervals (RIs) of serum aminotransferases and Gamma-glutamyl transferase (GGT) have been established many years ago. Recent RIs are not available. The prospective study was conducted to re-evaluate the RIs of liver enzymes and the effect of demographic and anthropometric variables on them in western Indian population. A total of 1059 blood donors comprised the study population. Anthropometry and serum liver enzymes levels were measured. Subjects were categorized into normal weight and overweight by using body mass index (BMI) and waist circumference (WC). For RI determination, non-parametric methodology recommended by IFCC/CLSI was adopted. Mann–Whitney test and Spearman’s rank correlation were used for statistical analysis. Upper limit of normal reference value of liver enzymes were lower in female compared to male. (ALT—23.55 F vs 36.00 M, GGT—34.58 F vs 36.20 M) When RI of liver enzymes were calculated according to body mass index, the upper limit of normal of ALT and GGT were higher in overweight group compared to normal weight group. (ALT—38.00 vs 27.00 IU/L and GGT—37.59 vs 35.26 IU/L). In both male and female, liver enzymes correlated significantly with age. WC and BMI were positively correlated with AST, ALT and GGT in both subgroups and the correlation was stronger in male. Demographic factors should be considered for making liver enzyme tests more clinically relevant. Gender based partitioning should be adopted for serum alanine aminotransferase (ALT) and GGT reference values for Western Indian population. 相似文献
49.
Arun Kumar Singh Sunita Tiwari Abhishek Gupta Kamla Kant Shukla Kumar Gaurav Chhabra Achileshwar Pandey Aditya Bhushan Pant 《Indian journal of clinical biochemistry : IJCB》2015,30(3):255-262
Metabolic syndrome (MetS) is a cluster of interrelated common clinical disorders. The role of resistin in insulin sensitivity and MetS is controversial till date. So, the aim of the present study was to investigate the relationship of plasma resistin levels with markers of the MetS in Indian subjects. In a case control study, total 528 subjects were selected for the study. 265 (194 male and 71 female) were cases (with MetS) and 263 (164 male and 99 female) were controls (without MetS). Required anthropometric measurements and calculations were carried out accordingly. All the Biochemical estimations were carried out according to standard protocol. Resistin level was measured by the standard protocol (By ELISA i.e. enzyme linked immunosorbent assay) as illustrated in the kit. Insulin level was also measured by the standard protocol as illustrated in the kit and insulin resistance was calculated by the standard procedures. Plasma resistin levels were significantly higher in cases compared with controls (male = 13.05 ± 4.31 vs. 7.04 ± 2.09 ng/ml; p ≤ 0.001 and female = 13.53 ± 4.14 vs. 7.42 ± 2.30 ng/ml; p ≤ 0.001). Plasma resistin levels were well correlated with waist circumference, glucose, triglycerides, waist/hip ratio, systolic and diastolic blood pressure, high density lipoprotein, total cholesterol, serum low density lipoprotein, serum very low density lipoprotein, insulin and insulin resistance. Plasma resistin levels were elevated in presence of the MetS and were associated with increased metabolic risk factors. 相似文献
50.