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31.
Pradeep Venkatesh Garg Satpal Lalit Verma Tewari Hem Kumar Sheena Garg 《Indian journal of clinical biochemistry : IJCB》2001,16(1):9-14
Antioxidants are a small group of substances that protect living cells from the destructive consequences of powerful oxidizing
intermediates that can be formed from oxygen. Situations in which pro-oxidant mechanisms within the body are more active than
the antioxidant mechanisms (oxidative stress) predispose and contribute to the pathogenesis of several ailments in various
organs of the body. In the eye, pro-oxidant factors have been blamed for the causation of diseases such as age related macular
degeneration and senile cataract. The role of pro-oxidants in the genesis of certain diseases is well established however,
the effectivity of antioxidants provided to the body by dietary supplementation is inconclusive. In this article we provide
a review on the basic concepts of antioxidant-pro-oxidant interaction in relation to its effects on the eye. 相似文献
32.
Sweta T. Kothari Ranjana A. Deshmukh 《Indian journal of clinical biochemistry : IJCB》2006,21(1):15-26
Cytokines, viral load and opportunistic infections play an important role in HIV-disease progression. Hundred children vertically
infected with HIV were enrolled to determine mRNA levels of TNF-α, IL-10, IL-4 and IFN-γ. These levels were estimated by amplifying
cytokine mRNA from peripheral blood mononuclear cells. Severity of HIV was staged by the reduction in CD4
+ T cells and the onset of opportunistic infections. IL-10 mRNA levels were observed to increase with the severity. Despite
the rising IL-10 mRNA levels, TNF-α mRNA levels increased with severity of HIV and decrease in CD4
+ T cell counts. IL-4 mRNA levels increased with the reduction in CD4
+ T cell numbers. Depleting mRNA levels of IFN-γ contributed to the worsening of HIV disease. Increase in TNF-α and IL-4 levels
appended to the disease severity by upregulation of the viral replication. Increased IL-10 levels and decreased IFN-γ levels
predisposed the children to HIV associated opportunistic infections, which in return contributed to cytokine disarray. 相似文献
33.
Satisfaction is a condition that contributes to the development of intrinsic motivation and a continuing motivation to learn. Research that helps to identify the factors that contribute to learning satisfaction is useful for educators. This paper introduces the Cognitive-Motivational Model of Decision Satisfaction, a model that extends Kruglanski's work on closure and builds on Keller's work on the motivational aspects of instruction and learning. Focusing on decision-making activities in a learning context, this model recognizes the importance of information-processing in judgmental tasks and specifies confidence as a major contributing factor to learning satisfaction. Some potential applications to both classroom and computer-based learning environments are suggested. 相似文献
34.
V. G. Justin S.D Tarey T. Venkatesh 《Indian journal of clinical biochemistry : IJCB》1999,14(2):249-251
Routine investigations of a 70 year old male led to provisional diagnosis of anemia. However further investigations suggested
the possibilities of carcinoma of stomach associated with pernicious anemia, multiple myeloma and megaloblastic anemia. Finally
serum protein electrophoresis supported by the clinical suspicion confirmed multiple myeloma. 相似文献
35.
This article is the second part of our review of the important role that symmetry plays in atomic and subatomic physics. We
will concentrate on the discrete symmetries — parity, charge conjugation, and time reversal — that have played a significant
part in the development of the ‘standard model’ of particle physics during the latter part of the 20th century. The importance
of experimental tests of these symmetries, in both atomic and particle physics, and their sensitivity to new phenomena is
also discussed. To conclude, we describe how ‘symmetry breaking’ in the standard model leads to the generation of mass via
the Higgs mechanism and how the search for evidence of this symmetry violation is one of the principal goals of the Large
Hadron Collider, which began operating at CERN, Switzerland in 2009. 相似文献
36.
This feature presents research undertaken by Archana Deshmukh for her MA dissertation at the University of Brighton. She worked closely with Tom Roper, the Clinical Librarian at Brighton and Sussex University Hospitals NHS Trust, in a project to explore the feasibility of applying quantitative measures to evaluate the Clinical Librarian service. The investigation used an innovative participatory approach and the findings showed that although an exclusively quantitative approach to evaluation is not feasible, using a mixed methods approach is a way forward. Agreed outputs and outcomes could be embedded in a marketing plan, and the resulting framework could provide evidence to demonstrate overall impact. Archana graduated in July 2014, gaining a Distinction in the MA in Information Studies, and she is currently looking for work in the health information sector. 相似文献
37.
38.
One atom thick graphene is derived from graphite and is a new material; however, graphite has been a part of human history
for centuries. In this article we discuss why it generates so much excitement in a wide variety of scientific disciplines.
We emphasize its electronic and mechanical properties with an eye towards applications that may impact our lives sooner, rather
than later. We also review methods to make this wonder material, including the famous ‘scotch-tape’ technique that led to
the Nobel-Prize winning research. 相似文献
39.
P.?Chaitanya?DasEmail author G.?Srinivasa?Murthy C.?P.?GoplalaKrishnan P.?C.?Deshmukh 《Resonance》2004,9(6):74-85
A clear comprehension of the Newtonian notion of force remains elusive to many students due to lack of experience with observations
in a noninertial frame of reference. In this article is described a software that can be easily run on a desktop computer
and which acquaints the student user with the Newtonian notion of force. Fundamental principles of causality and determinism
in Newtonian mechanics are elucidated. 相似文献
40.
Herman S. Dsouza Geraldine Menezes T Venkatesh M.Sc. Ph.D. FACBI. FINASS 《Indian journal of clinical biochemistry : IJCB》2002,17(1):9-11
It is well known that lead exposure in the early period of pre pregnancy and antenatal life leads to serious health complications. In this case report, a five month old child who was suffering from encephalopathy was finally confirmed a victim of lead exposure, the source being the environment and the family. We report this case with complete clinical investigation including blood lead analysis. This case report highlights the various ways in which lead may accumulate in the body. It is also aimed at increasing awareness regarding the pathogenesis and clinical manifestations of lead toxicity. The literature survey done reveals that this is the youngest age at which lead toxicity has been documented in India. 相似文献