排序方式： 共有55条查询结果，搜索用时 15 毫秒
31.
S. Ramesh Babu M. D. Sadhnani M. Swarna P. Padmavathi P. P. Reddy 《Indian journal of clinical biochemistry : IJCB》2004,19(1):45-49
Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often
associated with altered serum gonadotropins and testosterone. FSH, LH and testosterone levels were estimated in 96 infertile
men of whom 35 were azoospermic, 35 were oligozoospermic, 11 were with varicocele and 15 were with histopathological abnormalities
like hypospermatogenesis, spermatid arrest and sertoli-cell only syndrome. Results showed statistically significant (p<0.05),
increase in the mean FSH and LH levels in all the infertile males studied when compared with the fertile controls (n=35).
However, there is no significant difference in the mean levels of testosterone between the infertile and fertile men. 相似文献
32.
Sarita N. Chavan Umesh More Shruti Mulgund Vishal Saxena Alka N. Sontakke 《Indian journal of clinical biochemistry : IJCB》2007,22(2):101-105
Osteoporosis encompasses a wide spectrum of conditions associated with imbalance of osteoclastic and osteoblastic activities.
The increased activity of osteoclasts leads to increased free radical formation and hence lipid peroxidation. Present study
probes into the role of antioxidants as a palliative treatment for osteoporosis. It involved 50 healthy controls and 75 clinically
diagnosed osteoporosis patients. Both the groups underwent baseline assessment of biochemical markers viz. osteoblastic markers:
serum Alkaline phosphatase. Free or ionic calcium and Inorganic phosphorus, osteoclastic markers: serum Tartarate resistant
acid phosphatase and Malondialdehyde and the antioxidant status: serum Superoxide dismutase and Erythrocyte reduced glutathione.
The osteoporotic group was then divided into groups A (Vitamin E-Evinal 400 mg), B (Vitamin C-Celin 500 mg), C (Vitamin E+C-Evinal+Celin)
for antioxidant supplementation for a period of 90 days. The results reveal that there is significant fall in concentration
of serum MDA (p<0.001), TrACP (p<0.01). Improvement in antioxidant status is reflected by significant rise in concentration
of serum SOD (p<0.001) and erythrocyte GSH (p<0.001) after 90 days of antioxidant supplementation in osteoporosis. The findings
indicate that on the whole bone status improved with prolonged antioxidant vitamin supplementation, which can be used as a
palliative treatment for osteoporosis. The efficacy is not affected whether the vitamins are administered singly or conjointly. 相似文献
33.
H. Ravi Kumar K. S. Devaraju B. M. Prakash S. Sampath Kumar S. V. Suresh Babu N. Ramachandraswamy H. P. Puttaraju 《Indian journal of clinical biochemistry : IJCB》2009,24(3):275-279
To establish/develop an assay method for measuring Ornithine Aminotransferase (EC.2.6.1.13) activity using rat brain mitochondria
as a source of enzyme in presence and absence of Pyridoxal Phosphate (PLP). The modified method, with the improved sensitivity,
is adopted for the assay of ornithine amino transferase activity in rat brain mitochondria. The enzyme activity was measured
at 620 nm, the study showed that reaction was optimum at 37°C for 30 minutes. The assay is sensitive enough to detect activity
at the order of nanomoles pyrroline-5-carboxylate/mg protein/minute and can be compared as an alternative to the radio isotopic
method which is more cumbersome and aminobenzaldehyde method which is less sensitive. The Km & Vmax shows maximum activity in the presence of Pyridoxal Phosphate (Coenzyme) concentration at 0.05mM when compared with absence
of Pyridoxal Phosphate as higher the concentration of Pyridoxal Phosphate affects the affinity of the enzyme to substrate.
The OAT activity in different tissues of the rat was also studied and highest activity was found in liver and kidney. 相似文献
34.
Priya Gururajan Prema Gurumurthy Pradeep Nayar Sai Babu A. Sarasabharati Dolice Victor K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2009,24(3):229-233
CD40-CD40L interaction plays a significant role in the pathogenesis of atherosclerosis and coronary artery disease. The clinical
predictive value of Soluble CD40 Ligand (sCD40L) was evaluated in patients with Acute Coronary Syndrome (ACS) and Non-Cardiac
Chest Pain (NCCP). The levels of serum soluble CD 40 ligand were measured by ELISA in 485 patients admitted to emergency care
unit, of which 89 patients were diagnosed as NCCP. The levels of sCD40L were significantly increased in patients with ACS
when compared to controls and NCCP. Receiver Operator Characteristic (ROC) Curve analysis showed sCD40L to be a good discriminator
between patients with ischemic heart disease and patients without ischemic heart disease. The area under the curve was found
to be 0.940 with 95% CI (0.915 to 0.960) (P<0.0001). The cut off value from the ROC curve was 2.99 ng/ml, above which sCD40L
was considered to be positive. Combined assessment of sCD40L, Troponin I and CK-MB enhanced the risk prediction and early
classification of patients. sCD40L seems to be a promising biomarker for identification and risk stratification for patients
with acute coronary syndrome. 相似文献
35.
36.
P. G. Babu 《Resonance》1998,3(8):46-55
This article tries to outline what game theory is all about. Part II explores concepts such as repeated games, social norms
and common knowledge.
This paper is based in part on a lecture given at the Centre for Theoretical Studies, Indian Institute of Science, Bangalore
as part of a lecture series on ‘learning and evolution’. I am grateful to Vivek Borkar and Sanjay Jain for this opportunity.
I thank the editor-in-charge of the paper for valuable comments. This is an expository article; no originality, other than
that of the organization of material, is claimed. 相似文献
37.
Journal of Science Education and Technology - Virtual labs have proven to be very versatile and valuable for providing realistic experience for students in STE (Science, Technology, and... 相似文献
38.
>An investigation is reported which tests the applicability of two American instruments designed to assess tertiary students’ evaluations of teaching effectiveness with 111 Indian graduate students. The scales were found to have generally high internal consistency reliability coefficients, most of the items were seen to be appropriate, and every item was considered of importance by at least some of the students. In addition, all but the Workload/Difficulty items clearly differentiated between ‘good’ and ‘poor’ lecturers. Further analysis generally supported the convergent and discriminant validity of those scales hypothesised to measure similar or dissimilar components of effective teaching. However, this analysis did indicate more overlap between aspects of teaching skill and enthusiasm than evident in Western studies. Factor analysis confirmed this finding as a strong main factor of teaching effectiveness plus minor factors referring to specific aspects of teaching were obtained. 相似文献
39.
Dhananjay Andure Kiran Pote Vishal Khatri Nitin Amdare Ramchandra Padalkar Maryada Venkata Rami Reddy 《Indian journal of clinical biochemistry : IJCB》2016,31(4):423-430
Lymphatic filariasis is a mosquito borne parasitic infection and can severely affect the normal working ability of an individual. Currently there is no vaccine available to prevent this infection and the development of a potential vaccine could effectively support the on-going mass drug administration program by World Health Organization (WHO). Filarial parasites have complex mechanisms to modulate the host immune responses against them. The glutathione-S-transferases (GST) are the important enzymes effectively involved to counteract the oxidative free radicals produced by the host. In the present study, we have shown that the mastomys which are fully permissible rodents for Brugia malayi when immunized with Wuchereria bancrofti recombinant GST (rWbGST) could induce 65.5 % in situ cytotoxicity against B. malayi infective (L3) larvae. There was a balanced Th1/Th2 immune response in the vaccinated animals, characterized by higher levels of WbGST-specific IgG1 and IgG2a antibodies and pronounced IFN-γ, IL-10 and IL-4 cytokines production by the spleen cells. 相似文献
40.
Hitender Singh Batra Parduman Singh Babu Lal Somani Ashish Gupta Sangeetha Sampath Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2007,22(2):106-108
Serum ferroxidase and albumin levels were determined in 98 patients of tubercuiosis, of whom 49 were freshly diagnosed, sputum
positive (group-I) & 49 were completely treated patients (group-II). Forty nine age and sex matched healthy individuals were
taken as controls. Mean±SD of serum ferroxidase and albumin levels in controls, group-I and group-II was found to be 864.35±106.35
IU/L & 3.91±0.234 g/dL, 1603.76±222.65 IU/L & 3.24±0.518 g/dL and 1001.78±201.63 IU/L & 3.82±0.43 g/dL, respectively. Serum
ferroxidase in group I was significantly higher as compared to controls and group-II (p<0.01). The decreased levels of serum
albumin in group I, as compared to control and group-II was statistically significant (p<0.01). Serum ferroxidase: albumin
ratio (Ferroxidase in International Unit per gram of albumin) in group I (50.47±10.36 IU/g) was significantly higher than
controls (22.22±3.3 IU/g), (p<0.001) while in group II it was significantly lower (26.72±7.18 IU/g, p<0.001) than group-I
and close to control values. Serum ferroxidase: albumin ratio (IU/g) can therefore be incorporated as a surrogate marker to
assist in diagnosis and prognosis of pulmonary tuberculosis. 相似文献