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Filippo Abbondanza Philip S. Dale Carol A. Wang Marianna E. Hayiou-Thomas Umar Toseeb Tanner S. Koomar Karen G. Wigg Yu Feng Kaitlyn M. Price Elizabeth N. Kerr Sharon L. Guger Maureen W. Lovett Lisa J. Strug Elsje van Bergen Conor V. Dolan J. Bruce Tomblin Kristina Moll Gerd Schulte-Körne Nina Neuhoff Andreas Warnke Simon E. Fisher Cathy L. Barr Jacob J. Michaelson Dorret I. Boomsma Margaret J. Snowling Charles Hulme Andrew J. O. Whitehouse Craig E. Pennell Dianne F. Newbury John Stein Joel B. Talcott Dorothy V. M. Bishop Silvia Paracchini 《Child development》2023,94(4):970-984
Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta-analysis (Ncases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions. 相似文献
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Recent simulations by Chen and Dorfman [Electrophoresis 35, 405–411 (2014)]
suggested that “tilting” the electric field with respect to the lattice vectors of a hexagonal post
array would lead to a substantial improvement in electrophoretic DNA separations therein. We
constructed such an array where the electric field is applied at an angle equidistant between the
two lattice vectors. This tilted array leads to (i) baseline resolution of 20 kbp DNA and λ DNA
(48.5 kbp) in a 4 mm channel and (ii) measurable separation resolutions for electric fields up to
50 V/cm, both of which are improvements over untilted post arrays of the same post density. The
predicted time required to reach a resolution of unity is approximately 5 min, independent of
electric field. The separations are more reproducible at higher fields. 相似文献
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Joel West 《Research Policy》2003,32(7):1259-1285
Computer platforms provide an integrated architecture of hardware and software standards as a basis for developing complementary assets. The most successful platforms were owned by proprietary sponsors that controlled platform evolution and appropriated associated rewards.Responding to the Internet and open source systems, three traditional vendors of proprietary platforms experimented with hybrid strategies which attempted to combine the advantages of open source software while retaining control and differentiation. Such hybrid standards strategies reflect the competing imperatives for adoption and appropriability, and suggest the conditions under which such strategies may be preferable to either the purely open or purely proprietary alternatives. 相似文献
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Joel Windle 《The Australian Educational Researcher》2011,38(3):311-327
This paper explores some of the processes through which an educational policy agenda can be generated in the media sphere. It casts light on the roles of journalists and various types of expert in these processes as they pertain to critical literacy. I argue for the usefulness of cross-field performance as a concept which helps to illuminate the special place of individuals who position themselves across journalistic, academic and political fields. The analysis is supported by examination of patterns in newspaper reporting and academic publication, which suggests that contestation of critical literacy serves as a staging device for a team of policy entrepreneurs, whose performances work to discredit and exclude other players. 相似文献
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Despite the impact of genetics on daily life, biology undergraduates understand some key genetics concepts poorly. One concept requiring attention is dominance, which many students understand as a fixed property of an allele or trait and regularly conflate with frequency in a population or selective advantage. We present the Dominance Concept Inventory (DCI), an instrument to gather data on selected alternative conceptions about dominance. During development of the 16-item test, we used expert surveys (n = 12), student interviews (n = 42), and field tests (n = 1763) from introductory and advanced biology undergraduates at public and private, majority- and minority-serving, 2- and 4-yr institutions in the United States. In the final field test across all subject populations (n = 709), item difficulty ranged from 0.08 to 0.84 (0.51 ± 0.049 SEM), while item discrimination ranged from 0.11 to 0.82 (0.50 ± 0.048 SEM). Internal reliability (Cronbach''s alpha) was 0.77, while test–retest reliability values were 0.74 (product moment correlation) and 0.77 (intraclass correlation). The prevalence of alternative conceptions in the field tests shows that introductory and advanced students retain confusion about dominance after instruction. All measures support the DCI as a useful instrument for measuring undergraduate biology student understanding and alternative conceptions about dominance. 相似文献
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