Studies on naturally dyed silk for painting exposed to museum display     

Boyoung Lee  Hyo seon Ryu 《文物保护研究》2014,59(5):S81-S84

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A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation     

Hyunjae Lee  Woohyun Park  Hyunryul Ryu  Noo Li Jeon 《Biomicrofluidics》2014,8(5)

Understanding the mechanism behind cancer metastasis is a major challenge in cancer biology. Several in vitro models have been developed to mimic a cancer microenvironment by engineering cancer–endothelial cell (EC) and cancer-stromal cell interactions. It has been challenging to realistically mimic angiogenesis, intravasation, and extravasation using macro-scale approaches but recent progress in microfluidics technology has begun to yield promising results. We present a metastasis chip that produce microvessels, where EC and stromal cells can be patterned in close proximity to tumor cells. The vessels are formed following a natural morphogenic process and have smooth boundaries with proper cell-cell junctions. The engineered microvessels are perfusable and have well-defined openings toward inlet and outlet channels. The ability to introduce cancer cells into different locations bordering to the microvessel wall allowed generation and maintenance of appropriate spatial gradients of growth factors and attractants. Cancer angiogenesis and its inhibition by anti-vascular endothelial growth factor (bevacizumab) treatment were successfully reproduced in the metastasis chip. Cancer intravasation and its modulation by treatment of tumor necrosis factor-α were also modeled. Compared to other models, the unique design of the metastasis chip that engineers a clear EC-cancer interface allows precise imaging and quantification of angiogenic response as well as tumor cell trans-endothelial migration. The metastasis chip presented here has potential applications in the investigation of fundamental cancer biology as well as in drug screening.  相似文献   

Parameter selection of pocket extraction algorithm using interaction interface     

KIM Chong-Min WON Chung-In RYU Joonghyun CHO Cheol-Hyung BHAK Jonghwa KIM Deok-Soo 《浙江大学学报(A卷英文版)》2006,7(9):1492-1499

INTRODUCTION Being the bio era, a significant research effort has been devoted to the study of proteins since they are related to the critical body functions. There have been many studies on proteins, with the voluminous related data being currently available in various pub- lic repositories including the Protein Data Bank (PDB) (CATH, 2006; DALI, 2006; MSD, 2006; RCSB PDB, 2006; SCOP Database, 2006). Given the atomic complexes of proteins, ana- lyzing interactions between them…  相似文献   

Correction     

Stephanie Allen  Clif Mims  Stephanie Roberts  Beaumie Kim  Jeeheon Ryu 《TechTrends》2004,48(2):75

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Revitalising Traditional Street Markets in Rural Korea: Design Thinking and Sense‐Making Methodology     

Hyun‐Kyung Lee 《The International Journal of Art & Design Education》2019,38(1):256-269

This article reports on an academic–industrial cooperation between students at the Ulsan National Institute of Science and Technology and a local foundation working to revitalise the Eonyang traditional market in Ulsan, South Korea. Students majoring in disciplines ranging from natural and applied sciences to business administration were introduced to design thinking, the double diamond model, and sense‐making as frameworks for generating creative outcomes. Those outcomes included media, signage and packaging, a display stand, an accessory for hikers, an artistic reinterpretation of the traditional store shutter, the design for a guesthouse and new packaging for locally produced products. Students presented their ideas at a public exhibition as team projects that involved 3D printing, CAD, Web‐design, graphic design and motion‐picture editing tools. The study reveals that students learn more effectively when pedagogy emphasises active learning and on‐site observation through design‐based integrated education. Its qualitative research involved interviews in which students experienced how design thinking methodology can transform a local economy. The methods reveal a new educational model centred upon creative and applied learning.  相似文献   

Fostering innovation through collaborative action research on the creation of shared instructional products by university science instructors     

Brenda M. Capobianco  David Eichinger  Sanjay Rebello  Minjung Ryu  Jeff Radloff 《Educational Action Research》2020,28(4):646-667

ABSTRACT

The purpose of this study is to profile four university science instructors who utilized action research as a means of learning how to develop and integrate a novel curriculum innovation – engineering design – in their science courses. Data included curriculum maps, lesson plans, notes from group meetings, and instructor reflections. Data analysis included document review and content analysis. Findings from this study suggest that action research effectively enabled the instructors to 1) establish shared ownership of the project goal – to improve preservice teachers’ learning of science through engineering design; 2) continuously test, revise, and recalibrate their shared instructional products; and 3) leverage multiple sources of innovation. Knowledge generated and used by the instructors represented different kinds of knowledge and distributed expertise resulting in products that were more useful and of higher quality than products created by individuals working alone. Consequently, this resulted in increased use of the products and increased instructor commitment to improve them over time. By simultaneously engaging in research and consequently taking specific action to inform their practice, science instructors in this study successfully created shared instructional products that both guided and enhanced their classroom teaching.  相似文献   

Robust ${\mathcal{H}}_{\infty }$ filtering of discrete-time nonhomogeneous Markovian jump systems with dual-layer operation modes     

Sung Hyun Kim 《Journal of The Franklin Institute》2019,356(1):697-717

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Development and validation of a mathematics anxiety scale for students     

Ho Kyoung Ko  Hyun Sook Yi 《Asia Pacific Education Review》2011,12(4):509-521

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What Does the No Child Left Behind Act Mean to Early Childhood Teacher Educators?: A Call for a Collective Professional Rejoinder     

Eunsook Hyun 《Early Childhood Education Journal》2003,31(2):119-125

This article is a call to become more critically aware of the new law commonly referred to as No Child Left Behind Act, which was put into effect in 2002 in the United States. The article is also an invitation to early childhood educators worldwide to engage in a dialogue that raises several questions: (a) How does such legislation affect early childhood educators and teacher preparation programs?; (b) How might teacher educators react and respond to the new law as they continuously practice informed decision-making about teacher preparation that is socially responsible? In view of these questions, it is a hope that we can see the initiation of nationwide dialogue regarding the issue of the No Child Left Behind Act. Primarily, how does the new law affect teacher educators and teachers? It is inevitable for us to be united and politically informed to prevent further scrutiny of questionable politically and economically driven educational practices in the United States, not to mention “test-heavy” evidence-based education reform.  相似文献   

The development and implementation of a web-based formative peer assessment system for enhancing students’ metacognitive awareness and performance in ill-structured tasks     

Minjeong Kim  Jeeheon Ryu 《Educational technology research and development : ETR & D》2013,61(4):549-561

An assessment was conducted of a web-based formative peer assessment system (WFPAS) emphasizing learners’ metacognitive awareness for their performance in ill-structured tasks. Results indicate that the WFPAS group achieved significantly higher scores for metacognitive awareness and performance in ill-structured tasks than the traditional peer assessment group and that a traditional peer assessment group achieved higher scores for metacognitive awareness than a self-assessment group. In addition, the WFPAS group showed significantly higher scores in motivation than the traditional peer assessment group. Results are explained from the perspective of peer interaction and scaffolding. The potential challenges and implications of the WFPAS are discussed.  相似文献