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31.
Leonardo Martín Pérez Francesc Codony Daniela López Leyton Mariana Fittipaldi Bárbara Adrados Jordi Morató 《Journal of Zhejiang University. Science. B》2010,11(1):27-29
Helicobacter pylori are ubiquitous Gram-negative bacteria with a high estimated level of infection in the world populations, but a majority of
the infected persons are asymptomatic. This pathogen has been classified by the World Health Organization as a class I carcinogen
and recognized as the causal agent of most peptic ulcers and chronic gastritis that might lead to stomach cancer. Although
not all the transmission pathways of these bacteria into humans have been properly identified, enough data have suggested
that the oral-oral or fecal-oral ones are the main infection routes. Helicobacter pylori have been detected in non-treated water and in drinking water, which suggested that water might be an important infection
source. As childhood is the critical period of infection, the aim of the present work was to examine the presence of Helicobacter pylori in soil samples from public playing areas of Spanish parks. 相似文献
32.
Intermittent hypoxia exposure in a hypobaric chamber and erythropoietin abuse interpretation 总被引：1，自引：0，他引：1
Abellan R Ventura R Remacha AF Rodríguez FA Pascual JA Segura J 《Journal of sports sciences》2007,25(11):1241-1250
The aim of this study was to assess the effect of intermittent hypoxia exposure on direct and indirect methods used to evaluate recombinant human erythropoietin (rhEPO) misuse. Sixteen male triathletes were randomly assigned to either the intermittent hypoxia exposure group (experimental group) or the control normoxic group (control group). The members of the experimental group were exposed to simulated altitude (from 4000 to 5500 m) in a hypobaric chamber for 3 h per day, 5 days a week, for 4 weeks. Blood and urine samples were collected before and after the first and the final exposures, and again 2 weeks after the final exposure. While serum EPO significantly increased after the first [from a mean 8.3 IU x l(-1) (s = 3.2) to 16.6 IU x l(-1) (s = 4.7)] and final exposures [from 4.6 IU x l(-1) (s = 1.4) to 24.8 IU x l(-1) (s = 9.3)], haemoglobin, percentage of reticulocytes, and soluble transferrin receptor were not elevated. Second-generation ON/OFF models (indirect rhEPO misuse detection) were insensitive to intermittent hypoxia exposure. The distribution of the urinary EPO isoelectric profiles (direct rhEPO misuse detection) was altered after intermittent hypoxia exposure with a slight shift towards more basic isoforms. However, those shifts never resulted in misinterpretation of results. The intermittent hypoxia exposure protocol studied did not produce any false-positive result for indirect or direct detection of rhEPO misuse in spite of the changes in EPO serum concentrations and urinary EPO isoelectric profiles, respectively. 相似文献
33.
Jordi Díaz-Gibson Mireia Civís Annabel Fontanet Susana López Miquel-Àngel Prats 《Cultura y Educación》2013,25(3):640-670
AbstractToday, educational change and innovation are a clear priority in educational centres across the world. This article analyses the strengths and opportunities presented by the process of educational innovation taking place in Catalonia from the perspective of school head teachers, employing a quanti-qualitative methodology using 227 surveys and 29 semi-structured interviews. The results locate the innovation process in a phase characterized by efforts aimed at updating existing practice, resistance to change generated by the system itself, and a lack of systematic reflection on current practice. Two strengths of the process reported relate to its scale and transversality across the whole territory on the one hand, and the importance that collaboration between teachers and schools is having in order to facilitate innovation. Other aspects highlighted are: the need to invest more planning in innovation processes; the need for the Deparment of Education to reflect on its own role within the process; and, finally, the need to develop the role of technologies as facilitators of innovation and communication. 相似文献
34.
The analysis of social networks has remained a crucial and yet understudied aspect of the efforts to measure Triple Helix linkages. The Triple Helix model aims to explain, among other aspects of knowledge-based societies, “the current research system in its social context” (Etzkowitz and Leydesdorff 2000:109). This paper develops a novel approach to study the research system from the perspective of the individual, through the analysis of the relationships among researchers, and between them and other social actors. We develop a new set of techniques and show how they can be applied to the study of a specific case (a group of academics within a university department). We analyse their informal social networks and show how a relationship exists between the characteristics of an individual’s network of social links and his or her research output. 相似文献
35.
Like other cultural industries, the theatrical film industry is subject to the ‘blockbuster effect’, where popular products often dominate their competition by orders of magnitude over relatively short-run time horizons. This paper investigates this particular feature of the industry and the implication for overall market size. Using simple regression analysis, a positive relationship between (product-level) market concentration and market size is established using weekly box office revenue data from the US motion picture industry. This empirical evidence supports a simple theoretical model of heterogeneous consumers who selectively participate in the market. 相似文献
36.
This special issue is devoted to the outcomes of the 48th International Conference of Education, “Inclusive Education: The Way of the Future” (Geneva, 25–28 November 2008). In addition to presenting the conclusions and recommendations from the conference, this introduction tackles a wide range of questions in the field of inclusive education on which there are still controversy and debate. The issue draws together a selection of articles that analyze these open debates at a deeper level. Special emphasis is placed on several issues: Should inclusive education be a comprehensive approach or follow a policy of piecemeal social engineering? How can educational systems pursue equity and quality simultaneously? What is the role of government, and of decentralization and autonomy? What teaching methods are needed, and what changes in teacher education, development and motivation? Finally, what are the roles of communities, social attitudes, and behaviours? 相似文献
37.
Early childhood education is a developmental period in which early symptoms of attention deficit hyperactivity disorder (ADHD) can be observed. This work examines the educational background of 206 children, from the ages of three to five years (109 of them with an ADHD diagnosis and 97 without a clinical diagnosis), by analysing 306 reports from their teachers. The aim of this study is to discover if these educational reports reflect differences in academic performance and behaviour between both groups. The 123 educational goals analysed in the reports have been classified into 15 categories. A nonparametric analysis (Chi square) was performed on each variable to compare ADHD/control groups. Our results claim that ADHD children show more difficulties in different curricular and behavioural aspects like attention, self-regulation, independence, motivation, basic learning, social relationships, motor skills and communication. These reports are useful in identifying children who are at risk of developing the disorder and in establishing intervention goals that decrease negative effects in children’s development. 相似文献
38.
Ángel Borrego Jordi Ardanuy Cristóbal Urbano 《The Journal of Academic Librarianship》2018,44(5):663-670
Academic libraries are increasingly called upon to demonstrate their value to their home institutions. Research collaboration with faculty resulting in the co-authorship of scholarly output is one possible way to demonstrate the alignment of the library with the institutional mission. Involvement in research also improves librarians' skills in offering research support services. This study explores the contribution of librarians to scholarly journals in fields other than Library and Information Science (LIS) as well as their collaboration practices with researchers in those fields. Results show an increasing number of papers published by library-affiliated authors in non-LIS journals between 2006 and 2015. The papers fall broadly into four areas: articles on topics related to LIS published in non-LIS journals; higher education and information literacy; systematic reviews and meta-analysis; and research collaboration in the faculty's areas of expertise. The study is limited by the difficulty in properly retrieving the scholarly output of librarians from bibliographic databases and the difficulty in ascertaining their contributions to published articles. 相似文献
39.
Weinberg Charles B. Otten Cord Orbach Barak McKenzie Jordi Gil Ricard Chisholm Darlene C. Basuroy Suman 《Journal of Cultural Economics》2021,45(2):239-262
The recent rise of digital technology in the delivery of entertainment casts doubt among industry stakeholders on whether movie theaters will continue to be the primary channel of the release of motion pictures. Despite the growth of competing outlets due to the spread of digitalization, we argue that the movie theater industry may benefit from digital technologies as well. Enhancing the cinemagoing experience, better matching of the cinemagoing experience to consumer preferences, and improving capacity utilization are crucial if movie theaters are to continue having a pivotal role in the distribution of filmed entertainment. In particular, our data analysis demonstrates that the use of new digital technologies and “big data” may be one way to turn the current threats into future opportunities for movie exhibitors. Therefore, managerial strategies that aim to raise the value proposition of theaters by enhancing the cinemagoing experience, and that boost adaptability to rapidly changing consumer preferences about how and when they view filmed entertainment, ought to be studied and implemented.
相似文献40.
Francesc Codony Bárbara Adrados Leonardo Martín Pérez Mariana Fittipaldi Jordi Morató 《Journal of Zhejiang University. Science. B》2009,10(12):867-869
The Catabacteriaceae is a new bacterial family with a unique member: Catabacter hongkongensis is a strictly anaerobic, non-sporulating, Gram-positive coccobacillus that is phylogenetically related to some clostridial
clusters. Little is known of its epidemiology and environmental distribution, but the inclusion of its 16S rRNA gene sequence
in GenBank has allowed it to be detected qualitatively. As a first approach for prospective surveys, a real-time polymerase
chain reaction (PCR) procedure to identify C. hongkongensis has been developed. The presence of Catabacteriaceae in 29 water bodies subjected to possible human or animal impact has
been investigated. Four of them were positive. The results confirm that highly polluted water can contain C. hongkongensis. 相似文献